No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Hyaluronic Acid Ingredients & Drug Interactions

by Roex

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Hyaluronic Acid is a dietary supplement by Roex with 1 active ingredient. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Hyaluronic Acid by Roex

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: hyaluronic acid, a naturally occurring substance your body uses to keep skin and connective tissue hydrated. The capsule also contains vegetable cellulose, microcrystalline cellulose, magnesium stearate, and silica as inactive ingredients — these are the binders and capsule material that hold everything together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: maintain healthy joints and skin hydration.
  • We looked for evidence on: Osteoarthritis, Aging skin, Dry eye, Wound healing, Joint flexibility, Skin moisture barrier.
  • The strongest evidence on file: Hyaluronic Acid is rated "Possibly Effective" for Dry eye (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Osteoarthritis, Wound healing.

Hyaluronic acid is possibly effective for dry eye and venous leg ulcers (slow-healing wounds on the lower leg). For aging skin, hay fever, and sexual dysfunction, the evidence we have isn't strong enough to rate it either way — there's simply not enough reliable research.

If you're considering it for any of those uses, talk it over with your doctor about what the science actually supports right now.

The evidence, ingredient by ingredient Hyaluronic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pregnancy and lactation data aren't on file for this ingredient. Because the safety information is limited, the facts advise against taking oral supplements unless your doctor says it's okay.

If you're pregnant or nursing and considering this product, talk with your doctor or pharmacist about whether it's right for you.

Side effects, ingredient by ingredient Hyaluronic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That doesn't mean none exist — just that none have been formally reported.

If you take medications regularly, check them against the tool on this page or ask your pharmacist.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Hyaluronic Acid by Roex may help with dry eye or leg ulcers based on the evidence we have, though it's not proven for aging skin or other uses. It's generally well tolerated, but long-term safety isn't fully known, and there's not enough data to recommend it in pregnancy or lactation without medical approval.

No interactions with medications are documented for this ingredient. Run it by your own doctor or pharmacist before starting, especially if you're pregnant, nursing, or taking regular medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hyaluronic Acid, straight from the product label.

Brand Roex
Barcode (UPC) 645245360603
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jan 25, 2020
DSLD ID 211484
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hyaluronic Acid by Roex, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
645245360603
IngredientAmount% DV
Hyaluronic Acid50 mg--

Other ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Helps maintain healthy joints and enhances movement and flexibility

Helps maintain healthy joints Helps hydrate skin Supports eye health

Precautions

Warning: Consult your physician prior to use if you are pregnant, nursing, have a medical condition or are taking medications.

Keep out of the reach of children.

Do not use if clear safety seal around bottle neck is broken or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store at room temperature, in a dry place.

General Statements

Nature's Moisturizer

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults, take 1 capsule twice a day 20 minutes before eating, as a dietary supplement or as directed by your doctor.

See for yourself

Hyaluronic Acid by Roex label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Hyaluronic Acid by Roex

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Hyaluronic Acid

No known
interactions
50 mg per serving Form: Glucuronic Acid

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

Hyaluronic Acid monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hyaluronic Acid by Roex Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Hyaluronic Acid. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Hyaluronic Acid, from the product label.

Roex

See all Roex products
Name
BIN Science LLC
Street Address
8310 South Valley Highway, St. 300
City
Englewood
State
CO
ZipCode
80112
Phone Number
800-645-0010
Web Address
www.roex.com
Pharmacist Counseling Corner

Hyaluronic Acid by Roex: Common Questions

Does Hyaluronic Acid by Roex interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Hyaluronic Acid. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Hyaluronic Acid contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does hyaluronic acid actually do?
It's a compound your body naturally makes to keep skin and tissues hydrated. The evidence shows it's possibly effective for dry eye and venous leg ulcers — those slow-healing wounds on the lower leg. For aging skin and hay fever, we don't have enough research to say whether it works.
Is it safe to take long-term?
Hyaluronic acid is generally well tolerated when taken by mouth, but the long-term safety of taking it as a supplement hasn't been fully studied. The product facts advise against taking oral supplements unless your doctor recommends it.
Can I take this while pregnant or breastfeeding?
There isn't enough safety data on this ingredient during pregnancy or lactation. The facts advise against oral supplements unless your doctor clears it. Talk with your doctor or pharmacist about your individual situation.
What side effects might I notice?
Taken by mouth, hyaluronic acid appears to cause few problems in most people. When applied to skin, it's occasionally caused redness, itching, eczema, or infection in open wounds. Eye drops with it have rarely caused eye pain.
Will this help my wrinkles?
The evidence for hyaluronic acid and aging skin isn't strong enough for us to rate it either way. There simply hasn't been enough reliable research. If you're curious about it for that purpose, ask your doctor what the current science actually shows.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hyaluronic Acid is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hyaluronic Acid label
Go deeper

The Full Monographs Behind Hyaluronic Acid’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Hyaluronic Acid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring