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Dietary supplement

Hydrangea Root 335 mg Ingredients & Drug Interactions

by Dr. Clark Research Association Dr. Clark Zentrum

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Hydrangea Root 335 mg is a dietary supplement by Dr. Clark Research Association Dr. Clark Zentrum with 1 active ingredient. Its ingredients are commonly taken for kidney and bladder stones, urinary tract complaints, enlarged prostate symptoms.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hydrangea. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Hydrangea Root 335 mg by Dr. Clark Research Association Dr. Clark Zentrum

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: hydrangea root at 335 mg per capsule. Hydrangea is a plant whose root is used in traditional herbal practice.

The capsule itself is made from gelatin.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hydrangea product and its label doesn't state a use — see Hydrangea's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't hold effectiveness ratings for hydrangea in our data, so the evidence for what it may do isn't established here.

The evidence, ingredient by ingredient Hydrangea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Human safety data for hydrangea are limited, and large or prolonged doses may cause unwanted effects. The product may cause gastroenteritis (stomach and intestinal upset), dizziness, or a feeling of tightness in the chest.

The safety data advises against use during pregnancy and while breastfeeding due to insufficient information.

Side effects, ingredient by ingredient Hydrangea

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hydrangea.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium for mood disorders, check with your pharmacist or doctor before using this product — hydrangea may increase lithium levels in your body and require a dose adjustment.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Hydrangea Root is a single-ingredient herbal supplement with very limited human safety data. If you take lithium, you'll want to check with your pharmacist or doctor before starting — this product may affect how your body handles that medication.

Talk with your pharmacist, especially if you're pregnant, breastfeeding, or taking any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hydrangea Root 335 mg, straight from the product label.

Brand Dr. Clark Research Association Dr. Clark Zentrum
Barcode (UPC) 7640116929470
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 223514
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hydrangea Root 335 mg by Dr. Clark Research Association Dr. Clark Zentrum, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
7640116929470
IngredientAmount% DV
Hydrangea335 mg--

Other ingredients: Hydrangea, Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement/Food Supplement

Suggested/Recommended/Usage/Directions

Adults and children 12 or more years of age: 1 capsule daily before a meal or as directed.

Precautions

Store out of reach of young children.

Dietary supplements/food supplements should not be used as a substitute for a varied diet. Do not exceed the stated recommended daily dose.

Storage

Store in a dry, cool place.

Formulation

Made in the USA.

General Statements

Nominal weight: 44 g % DV = % Daily Value

See for yourself

Hydrangea Root 335 mg by Dr. Clark Research Association Dr. Clark Zentrum label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Hydrangea Root 335 mg by Dr. Clark Research Association Dr. Clark Zentrum

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Hydrangea

Interacts with
1 drug
335 mg per serving

Hydrangea root has a long history in folk medicine, mainly for urinary and kidney stone complaints, but there is very little modern human research to...

Hydrangea monograph & interactions

Other (inactive) ingredients: Hydrangea, Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hydrangea Root 335 mg by Dr. Clark Research Association Dr. Clark Zentrum Drug Interactions

Want to check YOUR meds against Hydrangea Root 335 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Hydrangea Root 335 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Hydrangea1 drug type · 1 drug

Lithium

Hydrangea is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, hydrangea might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Hydrangea Root 335 mg, from the product label.

Dr. Clark Research Association Dr. Clark Zentrum

See all Dr. Clark Research Association Dr. Clark Zentrum products
Name
Dr. Clark Zentrum Limited
Street Address
152 Naxxar Road #7, SGN 9030
City
San Gwann
State
Malta
Web Address
www.drclark.com
Pharmacist Counseling Corner

Hydrangea Root 335 mg by Dr. Clark Research Association Dr. Clark Zentrum: Common Questions

Does Hydrangea Root 335 mg by Dr. Clark Research Association Dr. Clark Zentrum interact with any medications?
Yes. Based on its ingredients, Hydrangea Root 335 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hydrangea Root 335 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is hydrangea root used for?
Hydrangea root is used in traditional herbal practice, but we don't have established effectiveness ratings in our data for specific conditions it may address.
Can I take this while pregnant?
No — the safety data advises against use during pregnancy. Talk with your doctor or pharmacist for personalized advice about what's safe for you.
Can I take this while breastfeeding?
No — there is no reliable safety data, so it's best to avoid use while breastfeeding. Check with your doctor or pharmacist for safer alternatives.
What side effects might I experience?
Hydrangea may cause stomach and intestinal upset, dizziness, or a feeling of tightness in the chest. Human safety data are limited, so effects from large or prolonged doses aren't well known.
Is this safe for long-term use?
Human safety data are limited, and large or prolonged doses may cause unwanted effects. Talk with your pharmacist about how long it's safe for you to take this.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hydrangea Root 335 mg label
Go deeper

The Full Monographs Behind Hydrangea Root 335 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Hydrangea Root 335 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hydrangea 1 reference
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

See these in context on the Hydrangea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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