Major interaction on record — check this product against your medications before combining. Based on 8 of 11 ingredients. Check your meds →
Dietary supplement

HydroBCAA + Essentials Blackberry Lemonade Ingredients & Drug Interactions

by PS ProSupps

HydroBCAA + Essentials Blackberry Lemonade label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking HydroBCAA + Essentials Blackberry Lemonade against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

HydroBCAA + Essentials Blackberry Lemonade is a dietary supplement by PS ProSupps with 11 active ingredients. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 625 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are L-Tryptophan, Sodium, Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against HydroBCAA + Essentials Blackberry Lemonade by PS ProSupps

Ask about any prescription or over-the-counter medication and we check it for interactions with HydroBCAA + Essentials Blackberry Lemonade by PS ProSupps — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of HydroBCAA + Essentials Blackberry Lemonade by PS ProSupps

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 5 of its 11 active ingredients.
  • “2:1:1 BCAA Matrix” is a proprietary blend — the label gives one combined amount (7 Gram(s)) without saying how much of each component you get.
  • “Full-Spectrum EAA Matrix” is a proprietary blend — the label gives one combined amount (3 Gram(s)) without saying how much of each component you get.

This powder contains 11 active ingredients: the branched-chain amino acids L-leucine, L-isoleucine, and L-valine; the essential amino acids L-methionine, L-phenylalanine, L-histidine, L-threonine, L-tryptophan, and L-lysine; plus potassium and sodium for electrolyte support. These amino acids help your body build and repair muscle, and the electrolytes help maintain fluid balance and nerve function.

The product also contains inactive ingredients such as citric acid, natural flavors, sucralose, fruit juice, and vegetable juice.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Cystic fibrosis — rated "Likely Effective" (Sodium) (Natural Medicines).
  • On file: Neural tube birth defects — rated "Possibly Effective" (Methionine) (Natural Medicines).
  • On file: Herpes labialis (cold sores) — rated "Possibly Effective" (Lysine) (Natural Medicines).
  • On file: Cholera — rated "Possibly Effective" (Histidine) (Natural Medicines).
  • On file: Vitiligo — rated "Possibly Effective" (Phenylalanine) (Natural Medicines).

We hold effectiveness data for most of the amino acids in this product, but the evidence is mixed. L-methionine appears possibly effective for neural tube birth defects during pregnancy, though supplement safety in pregnancy is not well established.

L-phenylalanine is possibly effective for vitiligo but possibly ineffective for ADHD. L-histidine may be possibly effective for cholera.

L-threonine and L-tryptophan are both rated possibly ineffective for the conditions studied. L-lysine is possibly effective for cold sores.

For the remaining amino acids and electrolytes, we either hold insufficient evidence or no effectiveness ratings in our data.

The evidence, ingredient by ingredient Potassium Sodium Methionine Phenylalanine Histidine Threonine L-tryptophan Lysine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 8 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 8 of 8.
  • General safety write-ups exist for 8 of 8.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-methionine is generally well tolerated at food amounts but high-dose supplements should be used with medical guidance. Common side effects can include dizziness, drowsiness, and vomiting.

L-phenylalanine is generally tolerated but should not be used by people with PKU (phenylketonuria); common side effects include anxiety, constipation, headache, heartburn, insomnia, and nausea. L-tryptophan may cause belching, diarrhea, drowsiness, dry mouth, headache, lightheadedness, nausea, and stomach pain — it has a history of contamination issues, though the affected product was recalled decades ago.

L-lysine is generally well tolerated but may cause abdominal pain and diarrhea at higher amounts. Potassium and sodium are generally safe from food, but supplements can raise blood levels dangerously in people with kidney disease or on certain medications.

For pregnancy and breastfeeding, L-methionine and L-histidine are rated Likely Safe; L-phenylalanine is rated Unsafe during pregnancy; L-tryptophan is rated Possibly Unsafe during pregnancy; and L-lysine, L-threonine, and potassium have insufficient data. Talk with your doctor or pharmacist about whether this product is appropriate for you if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Potassium Sodium Methionine Phenylalanine Histidine Threonine L-tryptophan Lysine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 6 of the 8 matched ingredients can interact with medications — Lysine, L-tryptophan, Phenylalanine, Potassium, Threonine, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: lithium; Parkinson's medications.
  • For scale: 625 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist or doctor before taking this if you use levodopa for Parkinson's disease (Major risk from L-phenylalanine), or CNS depressants like sedatives or strong pain relievers (Major risk from L-tryptophan). Also verify use if you take blood pressure medications including ACE inhibitors, ARBs, or general blood pressure drugs; potassium-sparing diuretics; serotonergic antidepressants or migraine drugs; muscle relaxers like baclofen; lithium; corticosteroids; or older antidepressants called MAOIs (Moderate risks from various ingredients).

Minor caution applies to 5-HT4 agonists used for GI conditions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

This amino acid and electrolyte powder may help with muscle support during workouts, but the ingredient list means you need to check your medications carefully — especially if you take blood pressure drugs, potassium-sparing diuretics, antidepressants, anti-anxiety medications, or Parkinson's disease medication. The potassium and sodium content also matters if you have kidney disease.

Talk with your doctor or pharmacist before starting this product to make sure it fits your personal health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about HydroBCAA + Essentials Blackberry Lemonade, straight from the product label.

Brand PS ProSupps
Barcode (UPC) 818253026353
Net contents 13.75 Ounce(s); 390 Gram(s)
Market status On market
Date entered into DSLD Jul 18, 2023
DSLD ID 295385
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for HydroBCAA + Essentials Blackberry Lemonade by PS ProSupps, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
13 Gram(s)
Maximum serving Sizes:
13 Gram(s)
Servings per container
30
UPC/BARCODE
818253026353
IngredientAmount% DV
Calories0 Calorie(s)--
L-Leucine3.5 Gram(s)--
L-Isoleucine1.75 Gram(s)--
L-Methionine0 NP--
L-Phenylalanine0 NP--
L-Valine1.75 Gram(s)--
L-Histidine0 NP--
L-Threonine0 NP--
L-Tryptophan0 NP--
Added Sugars0 Gram(s)--
Total Sugars0 Gram(s)--
L-Lysine0 NP--
Potassium100 mg2%
Total Carbohydrate0 Gram(s)--
Sodium50 mg2%
2:1:1 BCAA Matrix7 Gram(s)--
Full-Spectrum EAA Matrix3 Gram(s)--

Other ingredients: Citric Acid, Natural Flavors, Silicon Dioxide, Calcium Silicate, Sucralose, Fruit juice, Vegetable Juice

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

There's a better you waiting to get out and if you're willing to put in the work, ProSupps is uniquely qualified to unleash your full potential. Having climbed to the top of the fitness mountain ourselves, we can show you how to get here through elite supplementation, education, and inspiration. We're here for your relentless pursuit of greatness, but nobody is going to do it for you. You have to Earn It.

Customer service contact info: phone: 1-888-575-7301 Email: [email protected]

USA, Int'l

Contents sold by weight, not volume, some settling may occur.

Formulation

Gluten free

Manufactured in a cGMP facility Plant based

0% Juice.

Seals/Symbols

Good Manufacturing Practice cGMP Certified Made In The USA with foreign & domestic ingredients

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Warning: This product is intended for healthy adults, 18 years of age or older.

Do not use if you're pregnant or nursing.

If you experience any adverse reaction, discontinue use. Do not use if safety seal is broken or missing.

Keep out of the reach of children.

Warning for California Residents: Consuming this product can expose you to lead which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to: www.P65Warnings.ca.gov

Formula

Full-spectrum BCAAS & EAAS 7 g BCAAs 10 g EAAs 150 mg Electrolytes Blackberry Lemonade Natural flavors

Essentials for performance HydroBCAA + Essentials is formulated with 150mg of Electrolytes and 10g of EAAs, 7g of which are BCAAs in a 2:1:1 ratio for optimal recovery and muscular development while rehydrating your body. Essential Amino Acids (EAAs) Essential Amino Acids are essential because the body is unable to produce them on its own and must be consumed. EAAs are critical for cellular energy & repair and muscle preservation. HydroBCAA + Essentials includes Essential Amino Acids and Branched Chain Amino Acids to maximize muscle protein synthesis. Branched Chain Amino Acids (BCAAs) Branched Chain Amino Acids (L-Leucine, L-Isoleucine & L-Valine) are the most critical of the essential amino acids and necessary to stimulate protein synthesis, prevent muscle breakdown, and maintain critical glycogen stores. HydroBCAA + Essentials is built to deliver 7g of BCAAs to the body fast and effectively.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Mix 1 scoop of HydroBCAA + Essentials with 8 - 10 oz. of cold water. HydroBCAA + Essentials can be used prior to training, during training, and after training for maximum efficacy.

Storage

Store in a cool, dry place. Protect from heat, light, and moisture.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

HydroBCAA + Essentials Blackberry Lemonade by PS ProSupps label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

HydroBCAA + Essentials Blackberry Lemonade label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in HydroBCAA + Essentials Blackberry Lemonade by PS ProSupps

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size13 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Potassium

Interacts with
62 drugs
100 mg per serving Form: Potassium Chloride

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Sodium

Interacts with
205 drugs
50 mg per serving Form: Sodium Citrate

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

2:1:1 BCAA Matrix

7 Gram(s) per serving
  • › L-Leucine
  • › L-Isoleucine
  • › L-Valine

Full-Spectrum EAA Matrix

3 Gram(s) per serving

Other (inactive) ingredients: Citric Acid, Natural Flavors, Silicon Dioxide, Calcium Silicate, Sucralose, Fruit juice, Vegetable Juice. These complete the product’s ingredient list but are not active constituents.

Interaction report

HydroBCAA + Essentials Blackberry Lemonade by PS ProSupps Drug Interactions

Want to check YOUR meds against HydroBCAA + Essentials Blackberry Lemonade?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
625Drugs
256 Major 369 Moderate

Ingredients driving the most interactions

L-Tryptophan 394
Sodium 205
Potassium 62
L-Phenylalanine 16
L-Threonine 3

Individual Drug Interactions

The ingredients in HydroBCAA + Essentials Blackberry Lemonade interact with 625 drugs. Click any drug to see the details.

6 of the 11 ingredients in HydroBCAA + Essentials Blackberry Lemonade interact with drugs. Each result below shows which ingredient is responsible. L-Tryptophan Sodium Potassium L-Phenylalanine L-Threonine L-Lysine

Each ingredient & the kinds of drugs it affects

For each ingredient in HydroBCAA + Essentials Blackberry Lemonade with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Tryptophan2 drug types · 394 drugs

Cns Depressants

Theoretically, concomitant use of L-tryptophan with CNS depressants might cause additive sedative effects.
Clinical research shows that L-tryptophan can cause fatigue and drowsiness.

Likelihood Probable Evidence B
Serotonergic Drugs

Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
L-tryptophan is a precursor to serotonin. Theoretically, combining serotonergic drugs with L-tryptophan might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.

Likelihood Possible Evidence D
L-Tryptophan full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions

L-Phenylalanine3 drug types · 16 drugs

Levodopa

Phenylalanine, especially in high doses, can reduce the effectiveness of levodopa.
Phenylalanine competes with levodopa for carrier-mediated transport into the brain. The resulting reduction in levels of levodopa in the brain can exacerbate tremor, rigidity, and the "on-off" phenomenon in patients with Parkinson disease.

Likelihood Probable Evidence B
Baclofen

Concomitant intake of phenylalanine may reduce the intestinal absorption of baclofen.
Phenylalanine and baclofen share the same intestinal carrier for absorption; phenylalanine competitively inhibits the absorption of baclofen, reducing its plasma levels.

Likelihood Possible Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use of L-phenylalanine and non-selective MAOIs might increase the risk of hypertensive crisis.
L-phenylalanine is metabolized to tyrosine. Some evidence suggests that L-phenylalanine, given with the non-selective MAOI pargyline, might prevent the elimination of tyramine, increasing the risk of hypertensive crisis. However, this was not reported in a small number of patients when using L-phenylalanine with the partially selective MAO-B inhibitor, selegiline.

Likelihood Possible Evidence D
L-Phenylalanine full monograph & interactions

L-Threonine1 drug type · 3 drugs

Nmda Antagonists

Theoretically, threonine might decrease the effects of NMDA antagonists.
Threonine increases central nervous system (CNS) glycine levels. Glycine seems to bind a site on NMDA receptors and enhance the activity of the receptors.

Likelihood Likely Evidence B
L-Threonine full monograph & interactions

L-Lysine1 drug type · 1 drug

5-Ht4 Agonists

Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.

Likelihood Unlikely Evidence D
L-Lysine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for HydroBCAA + Essentials Blackberry Lemonade, from the product label.

PS ProSupps

See all PS ProSupps products
Name
ProSupps USA, LLC.
Street Address
5757 Main Street, Suite 205
City
Frisco
State
Texas
ZipCode
75034
Phone Number
1-888-575-7301
Web Address
ProSupps.com
Pharmacist Counseling Corner

HydroBCAA + Essentials Blackberry Lemonade by PS ProSupps: Common Questions

Does HydroBCAA + Essentials Blackberry Lemonade by PS ProSupps interact with any medications?
Yes. Based on its ingredients, HydroBCAA + Essentials Blackberry Lemonade has a known interaction with 625 medications, including 256 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
HydroBCAA + Essentials Blackberry Lemonade contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
It depends on which ingredient concerns you. L-methionine and L-histidine are rated Likely Safe; L-phenylalanine is rated Unsafe in pregnancy; and L-tryptophan is rated Possibly Unsafe in pregnancy. Other amino acids have insufficient data. Talk with your doctor or pharmacist for personalized advice before using this product during pregnancy or while breastfeeding.
What side effects might I notice from L-tryptophan?
Common side effects include drowsiness, diarrhea, dry mouth, headache, lightheadedness, nausea, and stomach pain. It may also cause belching and flatulence. Serious effects are rare but have been associated with a contamination issue from decades ago.
Is this product safe for people with high blood pressure or kidney disease?
The potassium and sodium in this product interact with blood pressure medications and can build to dangerous levels in people with kidney disease. Talk with your doctor or pharmacist about whether this is right for you if you have either condition.
What does L-phenylalanine do, and who should avoid it?
L-phenylalanine is an amino acid your body uses for protein and neurotransmitters. It should be avoided by people with PKU (phenylketonuria), and it can interfere with levodopa, a medication for Parkinson's disease. People taking older antidepressants called MAOIs should also be cautious.
Does this powder actually help build muscle?
This product contains branched-chain amino acids and essential amino acids your body uses to build and repair muscle, especially around workouts. However, we do not hold specific effectiveness ratings for muscle gain or athletic performance in our data.
What are the inactive ingredients?
The inactive ingredients are citric acid, natural flavors, silicon dioxide, calcium silicate, sucralose, fruit juice, and vegetable juice — these are fillers and flavor agents rather than active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if HydroBCAA + Essentials Blackberry Lemonade is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

HydroBCAA + Essentials Blackberry Lemonade label
Go deeper

The Full Monographs Behind HydroBCAA + Essentials Blackberry Lemonade’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Methionine

Methionine is an essential amino acid that your body needs for protein building and many basic chemical reactions. Most people get enough from a normal diet, and supplements are generally no...

Read the full Methionine monograph → Herb & supplement monograph

Phenylalanine

Interacts with 16 drugs

Phenylalanine is an essential amino acid the body uses to make brain chemicals like dopamine and norepinephrine. Some people take it for mood, vitiligo, or pain, but the evidence is mostly l...

Read the full Phenylalanine monograph → Herb & supplement monograph

Histidine

Histidine is an essential amino acid your body needs to build proteins and to make compounds like histamine and carnosine. Most people get enough from a normal diet, and good-quality researc...

Read the full Histidine monograph → Herb & supplement monograph

Threonine

Interacts with 3 drugs

Threonine is an essential amino acid your body needs but cannot make, so you must get it from food or supplements. Most people get plenty from a normal diet, and high-quality evidence for ta...

Read the full Threonine monograph → Herb & supplement monograph

L-tryptophan

Interacts with 394 drugs

L-tryptophan is an essential amino acid the body uses to make serotonin and melatonin, and people take it to support sleep and mood. The evidence for supplement use is limited and mixed, and...

Read the full L-tryptophan monograph → Herb & supplement monograph

Lysine

Interacts with 1 drug

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to try to prevent or shorten cold sores, but...

Read the full Lysine monograph →
Sources

Sources & How We Checked

HydroBCAA + Essentials Blackberry Lemonade's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 117 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Methionine 12 references
  1. La Vecchia C, Negri E, Franceschi S, Decarli A. Case-control study on influence of methionine, nitrite, and salt on gastric carcinogenesis in northern Italy. Nutr Cancer 1997;27:65-8. PubMed
  2. Btaiche IF, Khalidi N. Parenteral nutrition-associated liver complications in children. Pharmacotherapy 2002;22:188-211.. PubMed
  3. Cottington EM, LaMantia C, Stabler SP, et al. Adverse event associated with methionine loading test: a case report. Arterioscler Thromb Vasc Biol 2002;22:1046-50.. PubMed
  4. Anon. Should methionine be added to paracetamol formulations? Drug Ther Perspect 1997;10:11-3. DOI
  5. Smulders, Y. M., Rakic, M., Slaats, E. H., Treskes, M., Sijbrands, E. J., Odekerken, D. A., Stehouwer, C. D., and Silberbusch, J. Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and c
  6. McAuley, D. F., Hanratty, C. G., McGurk, C., Nugent, A. G., and Johnston, G. D. Effect of methionine supplementation on endothelial function, plasma homocysteine, and lipid peroxidation. J.Toxicol.Clin.Toxicol. 1999;37(4):435-440. PubMed
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Phenylalanine 23 references
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Histidine 3 references
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Threonine 4 references
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L-tryptophan 18 references
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Lysine 7 references
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See these in context on the Lysine monograph →

Potassium 12 references
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Sodium 38 references
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See these in context on the Sodium monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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