No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Hydrolyzed Collagen Peptides Ingredients & Drug Interactions

by Natures Craft

Powder Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

Hydrolyzed Collagen Peptides is a dietary supplement by Natures Craft with 2 active ingredients. Its ingredients are commonly taken for skin health and wrinkles, joint pain and osteoarthritis, bone health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Hydrolyzed Collagen Peptides by Natures Craft

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Natures Craft Hydrolyzed Collagen Peptides is a single-ingredient product: Collagen Peptide Complex. Collagen peptides are short chains of amino acids — the building blocks of protein — created by breaking down collagen from animal sources.

You're getting a concentrated protein source designed to support skin, joints, and connective tissue.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Collagen Peptides's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Supplement diet with additional protein.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Muscle strength, Sarcopenia, Protein sufficiency — and 2 related terms.
  • The closest evidence on file: Collagen Peptides is rated "Possibly Ineffective" for Muscle strength (Natural Medicines).
  • Also on file: Collagen Peptides is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Exercise-induced muscle soreness, Sarcopenia, Exercise-induced muscle damage.

The evidence for collagen peptides is mixed. For aging skin and dry skin, the data rates them as possibly effective, meaning there's some promising research but it's not conclusive.

For muscle strength, the evidence suggests they're possibly ineffective. For acne and athletic performance, we don't have enough reliable evidence to rate them either way.

The evidence, ingredient by ingredient Collagen Peptides

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Collagen peptides are generally well tolerated as a dietary protein. Orally, they may cause nausea, an upset stomach (dyspepsia), diarrhea, or flatulence, but these side effects are rare.

The product hasn't been well studied in pregnancy, so check with your doctor before using it if you're pregnant. Little safety data exists during breastfeeding either, so caution is advised if you're nursing.

Side effects, ingredient by ingredient Collagen Peptides

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient we checked. You're clear to use the search tool on this page if you want to verify your specific medications, or ask your pharmacist.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

This is a straightforward protein supplement with no known drug interactions. It may help aging or dry skin, though the evidence isn't rock-solid.

If you're pregnant or breastfeeding, talk to your doctor first. For muscle strength, the data doesn't support it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hydrolyzed Collagen Peptides, straight from the product label.

Brand Natures Craft
Net contents 1 Pound(s); 454 Gram(s)
Market status On market
Date entered into DSLD Oct 22, 2021
DSLD ID 256367
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hydrolyzed Collagen Peptides by Natures Craft, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10 Gram(s)
Maximum serving Sizes:
10 Gram(s)
Servings per container
45
IngredientAmount% DV
Calories35 Calorie(s)--
Protein9 Gram(s)--
Collagen Peptide Complex10 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: 1 serving daily to supplement the diet with additional protein or as directed by a healthcare professional. Mix with water or beverage of your choice. Do not use this product as a meal replacement or exceed suggested use without the supervision of a healthcare professional.

General Statements

Typical amino acid profile per serving L-Alanine 8.8% L-Arginine 8.2% L-Aspartic acid 4.9% L-Glutamic acid 10.9% L-Glycine 20.8% L-Histidine (EAA***) 0.8% L-Hydroxylysine 0.5% L-Hydroxyproline 13.1% L-Isoleucine (BCAA**/***) 1.3% L-Leucine (BCAA**/***) 2.7% L-Lysine (EAA***) 3.1% L-Methionine (EAA***) 0.7% L-Phenylalanine (EAA***) 1.6% L-Proline 14.7% L-Serine 3.2% L-Threonine (EAA***) 2.0% L-Tyrosine 0.2% L-Valine (BCAA**/***) 2.4% **Branch chain amino acids ***Essential amino acids

Nature at its finest

Please recycle.

Formulation

This "Typical amino acid profile" represents the average ratio of amino acids naturally-occurring in this product. These numbers can slightly fluctuate from batch to batch as with all natural protein sources. Collagen is not a complete protein.

Non-GMO formula

Advanced protein powder Supports hair, skin & nail growth

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

This product is intended to supplement the diet with additional protein and should not be used as a meal replacement.

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Good Manufacturing Practice Sourced from a GMP Certified Facility Quality Assured

Formulated in the U.S.A.

See for yourself

Hydrolyzed Collagen Peptides by Natures Craft label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Hydrolyzed Collagen Peptides by Natures Craft

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size10 Gram(s) Dosage formPowder Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

9 Gram(s) per serving

Collagen Peptide Complex

No known
interactions
10 Gram(s) per serving Form: Hydrolyzed Collagen Type I & III

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is...

Collagen Peptide Complex monograph & interactions
Interaction report

Hydrolyzed Collagen Peptides by Natures Craft Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Hydrolyzed Collagen Peptides. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Hydrolyzed Collagen Peptides, from the product label.

Natures Craft

See all Natures Craft products
Name
Nature's Craft
City
Monsey
State
NY
ZipCode
10952
Phone Number
408-599-3841
Web Address
shopnaturescraft.com
Pharmacist Counseling Corner

Hydrolyzed Collagen Peptides by Natures Craft: Common Questions

Does Hydrolyzed Collagen Peptides by Natures Craft interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Hydrolyzed Collagen Peptides. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Hydrolyzed Collagen Peptides contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will collagen peptides interact with my medications?
No interactions are documented in our data for collagen peptides. That said, it's always smart to run your exact medications through the search tool on this page or ask your pharmacist to be certain.
Can I take this if I'm pregnant?
Collagen peptides haven't been well studied in pregnancy. There isn't enough data to say it's safe or unsafe, so check with your doctor before starting it.
Is it safe to use while breastfeeding?
Little safety data exists for collagen peptides during breastfeeding, so caution is advised. Talk to your doctor or pharmacist before using it.
What side effects might I get?
Nausea, upset stomach, diarrhea, and flatulence are possible, but they're rare. Collagen peptides are generally well tolerated overall.
Does this actually work for wrinkles and aging skin?
The evidence says possibly effective — there's some research backing it, but it's not definitive. For dry skin, the rating is the same. Your results may vary.
Will it help me build muscle or improve athletic performance?
For muscle strength, the evidence suggests it's possibly ineffective. For athletic performance, we don't have enough reliable evidence to say either way.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hydrolyzed Collagen Peptides is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hydrolyzed Collagen Peptides label
Go deeper

The Full Monographs Behind Hydrolyzed Collagen Peptides’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Hydrolyzed Collagen Peptides's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Collagen Peptides 2 references
  1. Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
  2. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed

See these in context on the Collagen Peptides monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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