No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Indigo Ingredients & Drug Interactions

by Hawaii Pharm

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Indigo is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for colds and flu-like illness, sore throat, fever.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Indigo by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Indigo Leaf Extract, Dry — a concentrated form of indigo from the Isatis plant. It's a liquid formulation, so you're getting the extract suspended in alcohol, water, and glycerin.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Isatis's overall clinical evidence instead.

Moderate

Some clinical evidence supports Isatis for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Psoriasis — rated "Possibly Effective" (Natural Medicines).

Indigo Leaf Extract has possibly effective evidence for psoriasis — the strongest rating in the data we hold. For respiratory tract infections, prostate cancer, ulcerative colitis, hepatitis, and aging skin, the evidence isn't established enough to rate.

That doesn't mean it doesn't work; it means human studies are either limited or missing for those uses.

The evidence, ingredient by ingredient Isatis

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The main caution is that human safety data for indigo are limited, and traditional use has mostly been short-term. If you're pregnant, the safety data advise against it — talk with your doctor or pharmacist for personalized advice.

The same goes for breastfeeding: there isn't enough reliable data to know either way, so that's a conversation to have with your own healthcare provider. We hold no adverse effect reports in our data.

Side effects, ingredient by ingredient Isatis

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient we could check. That said, always let your doctor or pharmacist know you're taking this product so they can review it against your full medication list.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and some safety-information gaps remain.

If you're considering indigo for psoriasis, it may be worth exploring — the evidence leans possibly effective. If you're pregnant, breastfeeding, or have other health conditions, check with your doctor or pharmacist before starting.

No interactions are documented with the medications we could check, but your healthcare provider can confirm it fits your full picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Indigo, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253628879
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 301720
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Indigo by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
840253628879
IngredientAmount% DV
Indigo Leaf Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Organic Alcohol Based USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR-code to get 15% discount on your next purchase. Limited time deal.

Formula

Isatis tinctoria

Organic Alcohol Based

Formulation

Only natural ingredients Purity is laboratory tested and verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Not tested on animals

Organic Alcohol Based

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

See for yourself

Indigo by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Indigo by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Indigo Leaf Extract, Dry

No known
interactions
983 mg per serving Form: Isatis tinctoria Leaf Extract, Dry

Isatis is a plant long used in traditional Chinese medicine, mainly for sore throats, fevers, and colds. Modern evidence in people is very limited, so...

Indigo Leaf Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Indigo by Hawaii Pharm Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Indigo. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Indigo, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St. Ste. 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-854-2924
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Indigo by Hawaii Pharm: Common Questions

Does Indigo by Hawaii Pharm interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Indigo. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Indigo contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does indigo actually work for psoriasis?
The evidence rates it as possibly effective for psoriasis, which is the strongest rating we have for this product. That means some support exists, but more research would help. Your results may vary, and it's worth talking with your doctor about whether to try it alongside other treatments.
Can I take this if I'm pregnant?
The safety data advise against it during pregnancy. There isn't enough reliable information to say it's safe, so talk with your doctor or pharmacist before taking it if you're pregnant or planning to become pregnant.
What about breastfeeding?
There's no reliable safety data for breastfeeding, so the recommendation is to avoid it while nursing. Speak with your pharmacist or doctor if you're breastfeeding and interested in trying indigo.
Are there any side effects I should know about?
We hold no adverse effects data in our records for indigo. That said, human safety information is limited overall, so if you notice anything unusual after starting, let your doctor know.
Does the alcohol content matter in the liquid form?
This product is made with alcohol as a preservative and carrier for the extract. If you need to avoid alcohol for any reason — pregnancy, breastfeeding, certain medications, or personal choice — let your pharmacist know so you can explore other options.
Can I use this for other skin conditions besides psoriasis?
The data we hold only establish possibly effective evidence for psoriasis. For other skin concerns like aging skin, the evidence isn't rated — meaning it's not established enough to say whether it works. Your doctor can help you decide if it's worth trying for your specific condition.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Indigo is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Indigo label
Go deeper

The Full Monographs Behind Indigo’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Indigo's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Isatis 3 references
  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source
  3. About Herbs, Botanicals & Other Products — Memorial Sloan Kettering Cancer Center Source

See these in context on the Isatis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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