Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

InflammaForce Ingredients & Drug Interactions

by Energetix

InflammaForce label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking InflammaForce against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

InflammaForce is a dietary supplement by Energetix with 3 active ingredients. Its ingredients are commonly taken for inflammation and swelling, sinus and respiratory congestion, pain after surgery or injury.Based on those ingredients, 1,011 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Indian Frankincense, Serrapeptase. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against InflammaForce by Energetix

Ask about any prescription or over-the-counter medication and we check it for interactions with InflammaForce by Energetix — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of InflammaForce by Energetix

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

InflammaForce contains 3 active ingredients. Serrapeptase is an enzyme with fibrin-breaking properties.

Pancreatin 8X is a pancreatic enzyme blend that supports digestion. Indian frankincense (Boswellia serrata) is a plant resin traditionally used for inflammation and joint support.

The capsules also contain vegetarian capsule material, rice starch, and silica as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Inflammation and joint pain support.
  • We looked for evidence on: Asthma, Back pain, Exercise-induced muscle soreness, Inflammatory bowel disease (IBD), Knee pain, Osteoarthritis — and 4 related terms.
  • The strongest evidence on file: Boswellia Serrata is rated "Possibly Effective" for Osteoarthritis (Natural Medicines).
  • Also on file: Boswellia Serrata is rated "Insufficient Reliable Evidence To Rate" for Asthma, Exercise-induced muscle soreness, Postoperative pain, Rheumatoid arthritis (RA), and more.
  • Also on file: Serrapeptase is rated "Insufficient Reliable Evidence To Rate" for Asthma.

For serrapeptase, the evidence we hold rates it insufficient to be reliable for chronic bronchitis, asthma, atherosclerosis, back pain, and osteoporosis. For Indian frankincense, the data we hold rates it possibly effective for osteoarthritis, but insufficient reliable evidence for hay fever, Alzheimer disease, asthma, and cluster headache.

We hold no effectiveness data for pancreatin 8X.

The evidence, ingredient by ingredient Serrapeptase Boswellia Serrata

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Serrapeptase is generally well tolerated in the short term, though long-term safety isn't well studied. The most common side effects are stomach pain, nausea, and upset stomach — though studies show these occur at the same rate as placebo.

A rare serious effect is bullous pemphigoid (a blistering skin condition). Indian frankincense is also generally well tolerated short-term, but quality and dose vary widely between products.

Common side effects include abdominal pain, diarrhea, headache, heartburn, nausea, and itching; dizziness and vertigo have also been reported in some clinical trials. Rarely, large amounts may cause bezoar formation (an intestinal mass).

For pregnancy, the safety data advises against serrapeptase — not enough data to know it's safe. The same applies to Indian frankincense while breastfeeding.

Indian frankincense is rated likely safe in pregnancy, but serrapeptase is not, so talk with your doctor before taking this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Serrapeptase Boswellia Serrata

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Boswellia Serrata, Serrapeptase.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 1,012 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you're on blood thinners or antiplatelet drugs (such as warfarin, aspirin, or clopidogrel), since serrapeptase may raise bleeding risk. Also flag any medications your liver metabolizes heavily — including many antidepressants, heart and blood pressure drugs, certain antihistamines, and immunosuppressants — because Indian frankincense may raise their levels.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

InflammaForce may be worth considering if you're looking for enzyme and herbal support for inflammation, but the interactions are serious — especially if you take blood thinners or medications broken down by liver enzymes. Before you start, have your doctor or pharmacist review your exact medications against this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about InflammaForce, straight from the product label.

Brand Energetix
Barcode (UPC) 364578131611
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 22826
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for InflammaForce by Energetix, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
364578131611
IngredientAmount% DV
Serrapeptase10 mg--
Pancreatin 8X200 mg--
Indian Frankincense424 mg--

Other ingredients: Vegetarian Capsules, Rice Starch, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Tamper-proof. Do not use if safety seal is broken or missing.

Keep out of reach of children.

Storage

Store in cool, dry place out of direct sunlight.

General Statements

LOT T8315 MFD MAY 2012 {recycle} Please recycle.

NUTRITIONAL

FDA Statement of Identity

Dietary Supplement

Formula

Enzyme Formulation with Serrapeptase and Boswellia

Formulation

Does Not Contain: Dairy or Dairy Derivatives, Stabilizers, Oils, Fats, Corn, Gluten, Maltodextrin, Salt, Alcohol, Coloring, Egg, Yeast, MSG, Irradiated Ingredients, Added Flavoring or Preservatives.

Suggested/Recommended/Usage/Directions

As a dietary supplement take 2 capsules three times daily or as directed by your healthcare professional.

General

r09-11

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

InflammaForce by Energetix label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

InflammaForce label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in InflammaForce by Energetix

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Serrapeptase

Interacts with
122 drugs
10 mg per serving

Serrapeptase is an enzyme marketed to reduce inflammation, swelling, pain, and mucus, but the human evidence is limited and mostly low quality. If you...

Serrapeptase monograph & interactions

Pancreatin 8X

200 mg per serving

Indian Frankincense

Interacts with
952 drugs
424 mg per serving Form: Boswellic Acid

Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoart...

Indian Frankincense monograph & interactions

Other (inactive) ingredients: Vegetarian Capsules, Rice Starch, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

InflammaForce by Energetix Drug Interactions

Want to check YOUR meds against InflammaForce?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,011Drugs
1,011 Moderate

Ingredients driving the most interactions

Indian Frankincense 952
Serrapeptase 122

Individual Drug Interactions

The ingredients in InflammaForce interact with 1,011 drugs. Click any drug to see the details.

2 of the 3 ingredients in InflammaForce interact with drugs. Each result below shows which ingredient is responsible. Indian Frankincense Serrapeptase

Each ingredient & the kinds of drugs it affects

For each ingredient in InflammaForce with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Indian Frankincense6 drug types · 952 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2C19 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C19 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2C9 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C9 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2D6 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP3A4 enzymes. Other in vitro research shows that Boswellia serrata extract inhibits CYP3A4 enzymes at most concentrations, although it may modestly induce enzyme activity at low concentrations.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.
Some in vitro research suggests that Boswellia serrata extracts might inhibit mediators of autoimmune disorders such as leukotrienes and reduce production of antibodies and cell-mediated immunity. However, other in vitro research suggests that, when coupled with calcium ions, boswellic acids containing the keto group have immunostimulant properties within specific cell signaling pathways.

Likelihood Possible Evidence D
Indian Frankincense full monograph & interactions

Serrapeptase1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking serrapeptase with drugs that have antiplatelet or anticoagulant effects might increase the risk of bruising and bleeding.
In vitro research shows that serrapeptase has fibrinolytic activity.

Likelihood Possible Evidence D
Serrapeptase full monograph & interactions
The maker

Brand information

Manufacturer and brand details for InflammaForce, from the product label.

Energetix

See all Energetix products
Name
Energetix
Street Address
209 W. Deerfield Lane
City
Dahlonega
State
GA
ZipCode
30533
Phone Number
800.990.7085
Web Address
www.goenergetix.com
Pharmacist Counseling Corner

InflammaForce by Energetix: Common Questions

Does InflammaForce by Energetix interact with any medications?
Yes. Based on its ingredients, InflammaForce has a known interaction with 1,011 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
InflammaForce contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take InflammaForce if I'm pregnant or breastfeeding?
Not enough safety data exists for serrapeptase in pregnancy, so the safety data advises against it — talk with your doctor for personalized advice. Indian frankincense is rated likely safe in pregnancy, but there isn't enough data for breastfeeding, so you'd want to confirm with your pharmacist or doctor if you're nursing.
What are the most common side effects?
Serrapeptase may cause stomach pain, nausea, and upset stomach, though studies show these happen at the same rate as placebo. Indian frankincense can cause abdominal pain, diarrhea, headache, heartburn, nausea, and itching.
Is there evidence this actually works?
For serrapeptase, we hold insufficient reliable evidence for most conditions listed — chronic bronchitis, asthma, back pain, and others. Indian frankincense is possibly effective for osteoarthritis, but for other uses like hay fever and asthma, the evidence we hold is insufficient. We have no effectiveness data for pancreatin 8X.
Why does this product interact with so many medications?
Indian frankincense inhibits several liver enzymes (CYP2D6, CYP2C19, CYP1A2, CYP2C9, and CYP3A4) that break down a huge range of drugs — everything from antidepressants to heart medications. When those enzymes slow down, drug levels can rise and side effects increase. Serrapeptase adds bleeding risk with anticoagulants.
Can I take this long-term?
Both serrapeptase and Indian frankincense are generally well tolerated short-term, but long-term safety for serrapeptase isn't well studied, and quality varies widely between frankincense products. Talk with your doctor before using it long-term.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

InflammaForce label
Go deeper

The Full Monographs Behind InflammaForce’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Serrapeptase

Interacts with 122 drugs

Serrapeptase is an enzyme marketed to reduce inflammation, swelling, pain, and mucus, but the human evidence is limited and mostly low quality. If you want to try it, choose an enteric-coate...

Read the full Serrapeptase monograph → Herb & supplement monograph

Boswellia Serrata

Interacts with 952 drugs

Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoarthritis symptoms, but the overall evidenc...

Read the full Boswellia Serrata monograph →
Sources

Sources & How We Checked

InflammaForce's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Serrapeptase 2 references
  1. Tachibana M, Mizukoshi O, Harada Y, et al. A multi-centre, double-blind study of serrapeptase versus placebo in post-antrotomy buccal swelling. Pharmatherapeutica 1984;3:526-30..
  2. Mazzone A, Catalani M, Costanzo M, et al. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo. J Int Med Res 1990;18:379-88.. PubMed

See these in context on the Serrapeptase monograph →

Boswellia Serrata 16 references
  1. Gupta I, Gupta V, Parihar A, et al. Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur J Med Res 1998;3:511-4.
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Kimmatkar N, Thawani V, Hingorani L, et al. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine 2003;10:3-7. PubMed
  4. Liu JJ, Nilsson A, Oredsson S, et al. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 2002;23:2087-93. PubMed
  5. Wildfeuer A, Neu IS, Safayhi H, et al. Effects of boswellic acids extracted from a herbal medicine on the biosynthesis of leukotrienes and the course of experimental autoimmune encephalomyelitis. Arzneimittelforschung 1998;48:668-74.
  6. Gupta I, Parihar A, Malhotra P, et al. Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta Med 2001;67:391-5. PubMed
  7. Sengupta K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin. Arthritis Res Ther 2008;10:R85.
  8. Sengupta K, Krishnaraju AV, Vishal AA, et al. Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. Int J Med Sci 2010;7:366-77.
  9. Ernst E. Frankincense: systematic review. BMJ 2008;337:a2813. PubMed
  10. Kirste S, Treier M, Wehrle SJ, et al. Boswellia serratea extract acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. Cancer 2011;117:3788-95.
  11. Frank A, Unger M. Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction. J Chromatogr A 2006;111 PubMed
  12. Altmann A, Poeckel D, Fischer L, et al. Coupling of boswellic acid-incuded Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes. Br J Pharmacol 2004;141:223-32.
  13. El Fortia, M., Badi, H., Elalem, Kh, Kadiki, O., and Topov, Y. Olibanum bezoar: complication of a traditional popular medicine. East Mediterr.Health J 2006;12(6):927-929.
  14. Meshkat S, Mahmoodi Baram S, Rajaei S, et al. Boswellia serrata extract shows cognitive benefits in a double-blind, randomized, placebo-controlled pilot clinical trial in individuals who suffered traumatic brain injury. Brain Inj 2022;36(4):553-559. PubMed
  15. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  16. Valente IVB, Garcia D, Abbott A, et al. The anti-proliferative effects of a frankincense extract in a window of opportunity phase ia clinical trial for patients with breast cancer. Breast Cancer Res Treat 2024;204(3):521-530. PubMed

See these in context on the Boswellia Serrata monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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