Insane Veinz Strawberry Lemonade Ingredients & Drug Interactions
by Insane Labz
What is this page for?
First and foremost: checking Insane Veinz Strawberry Lemonade against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Insane Veinz Strawberry Lemonade is a dietary supplement by Insane Labz with 6 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 1,167 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beet Root Extract, Russian Tarragon Herb Extract, Agmatine Sulfate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Insane Veinz Strawberry Lemonade by Insane Labz
Ask about any prescription or over-the-counter medication and we check it for interactions with Insane Veinz Strawberry Lemonade by Insane Labz — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Insane Veinz Strawberry Lemonade by Insane Labz
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
This powder contains 6 active ingredients. Sodium is an electrolyte essential in small amounts but a concern at high doses — this product supplies it as a mineral.
Betaine anhydrous is an amino acid compound studied mainly for a rare metabolic disorder called homocystinuria. Agmatine sulfate is a naturally occurring compound derived from the amino acid arginine.
Beet root extract comes from the beetroot plant and is used for athletic performance and muscle recovery. Russian tarragon herb extract is made from the tarragon plant.
The product also lists chloride and an "Insane Veinz Blend" whose individual components aren't specified on the label. Inactive ingredients include citric acid, natural and artificial flavoring, silica, sucralose, calcium silicate, and FD&C Red #40 (a food dye).
Does it work?
Moderate evidence
The evidence for this product's purpose is mixed and mostly limited. Sodium is rated Likely Effective for cystic fibrosis and Possibly Effective for kidney damage caused by the antibiotic amphotericin B, but has Insufficient Reliable Evidence for bipolar disorder and congestive heart failure.
Betaine anhydrous is rated Effective for homocystinuria (a rare genetic disorder) and Possibly Effective for high homocysteine levels, but Insufficient Reliable Evidence for fatty liver disease, colorectal health, depression, or reflux. Agmatine sulfate has Insufficient Reliable Evidence for every condition listed in the data — alcohol use disorder, Alzheimer disease, anxiety, athletic performance, autism, and bipolar disorder.
Beet root extract is Possibly Effective for athletic performance and exercise-induced muscle soreness, but Possibly Ineffective for COPD and Insufficient Reliable Evidence for cholesterol and brain function. Russian tarragon has Insufficient Reliable Evidence for nausea after surgery.
Overall, the evidence for this product as marketed is not established in the data we hold.
How safe is it?
Well-documented data
Most ingredients are generally well tolerated in typical amounts, with some cautions. Sodium is well tolerated at normal dietary levels but high intake is linked to high blood pressure, heart strain, and kidney damage — avoid sodium supplements or very high intake without medical advice.
Betaine anhydrous commonly causes body odor, nausea, diarrhea, and GI upset; rare serious effects include brain swelling. Agmatine sulfate appears well tolerated short-term, though long-term human safety is not well studied; common effects include diarrhea, indigestion, and nausea.
Beet root extract is generally well tolerated and causes mainly red or black stools (harmless coloring); rare serious effects from large amounts include low blood calcium and kidney damage. Russian tarragon is lacking thorough safety evaluation; there's theoretical concern about long-term estragole (a natural component) raising cancer risk in animals, though this hasn't been shown in humans.
For pregnancy: sodium is rated Likely Safe but Possibly Unsafe (conflicting data); agmatine and tarragon are rated Possibly Unsafe to Likely Unsafe and should be avoided. Betaine anhydrous and beet extract have no pregnancy data on file.
For breastfeeding: agmatine and tarragon data advise against use; betaine anhydrous safety is not well established; sodium and beet extract have no breastfeeding data on file. Talk with your doctor or pharmacist about your individual situation before using this product during pregnancy or while breastfeeding.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your pharmacist or doctor if you take any of these: lithium (psychiatric medication — sodium can change its levels dangerously); antihypertensive drugs (blood pressure medications — sodium and agmatine may reduce effectiveness or lower pressure too much); antidiabetes drugs (blood sugar medications — agmatine may lower blood sugar too far); anticoagulant or antiplatelet drugs like warfarin, aspirin, clopidogrel, or heparin (blood thinners — tarragon may increase bleeding risk); CNS depressants like benzodiazepines, barbiturates, antihistamines, or tricyclic antidepressants (tarragon may increase sedation); monoamine oxidase inhibitors or MAOIs (antidepressants — tarragon may increase their effects); corticosteroids; didanosine; sodium phosphates; or tolvaptan. No interactions are documented in our data for chloride.
The bottom line
Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product combines ingredients with a mix of weak to unknown effectiveness for general health and performance. If you take lithium, blood pressure medications, blood sugar drugs, blood thinners, sedating drugs, or certain antidepressants, you'll need to discuss this product with your doctor or pharmacist before starting — the sodium and herbal components carry documented interactions.
Pregnant or breastfeeding? Check with your doctor or pharmacist first, as several ingredients lack safety data or are rated possibly unsafe in these settings.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Insane Veinz Strawberry Lemonade, straight from the product label.
| Brand | Insane Labz |
|---|---|
| Barcode (UPC) | 051497274702 |
| Net contents | 7.7 Ounce(s); 218 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2023 |
| DSLD ID | 298664 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Insane Veinz Strawberry Lemonade by Insane Labz, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Sodium | 100 mg | 4% |
| Betaine Anhydrous | 0 NP | -- |
| Agmatine Sulfate | 1250 mg | -- |
| Chloride | 100 mg | 3% |
| Beet Root Extract | 0 NP | -- |
| Insane Veinz Blend | 2290 mg | -- |
| Russian Tarragon Herb Extract | 0 NP | -- |
Other ingredients: Citric Acid, Natural and Artificial flavoring, Silica, Sucralose, Calcium Silicate, FD&C Red #40
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions for use: As a dietary supplement for adults, mix 1 scoop in 8-1 oz. of water and consume 30 minutes before activity/workout. Do not exceed 2 scoops within a 24 hour period. Advanced athletes should mix 2 scoops in 10-12 oz of water and consume 30 minutes before workout.
Precautions
Warning: Do not take Insane Veinz in excess of its recommended dosage.
Insane Veinz is not intended for use by persons under the age of 18.
Consult your physician prior to use if you have a medical condition, including but not limited to, heart, liver, kidney, or thyroid disease, psychiatric or epileptic disorders, difficulty urinating, diabetes, high blood pressure, cardiac arrhythmia, recurrent headaches, enlarged prostate or glaucoma. If you are a competitive athlete and/or or subject to drug testing, consult with your sanctioning body prior to use to ensure compliance. Discontinue use immediately if you experience any adverse reactions.
Keep out of reach of children
Seals/Symbols
Made in the USA Certified cGMP
General Statements
Summer series
Approved by mad chemist
Formula
Strawberry Lemonade Natural & artificial flavoring
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Insane Veinz Strawberry Lemonade by Insane Labz label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Insane Veinz Strawberry Lemonade by Insane Labz
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size4.3 Gram(s) Dosage formPowder Servings per container35 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsChloride
Insane Veinz Blend
Other (inactive) ingredients: Citric Acid, Natural and Artificial flavoring, Silica, Sucralose, Calcium Silicate, FD&C Red #40. These complete the product’s ingredient list but are not active constituents.
Insane Veinz Strawberry Lemonade by Insane Labz Drug Interactions
HelloPharmacist Interaction Report
Insane Veinz Strawberry Lemonade by Insane Labz contains several ingredients with documented interactions: sodium, agmatine sulfate, beet root extract, and Russian tarragon herb extract.
The most serious interaction is sodium's effect on lithium levels — high sodium intake can reduce lithium concentrations and effectiveness, while lowering sodium can raise levels to toxic ranges. This is a Moderate severity interaction that requires careful monitoring.
Read the full breakdown — every affected drug type, severity by severity
Sodium also interacts Moderately with antihypertensive drugs (blood pressure medications), corticosteroids, didanosine, sodium phosphates, tolvaptan, and other sodium-containing drugs — chiefly by raising the risk of high blood sodium levels or reducing medication effectiveness. Agmatine sulfate presents Moderate theoretical risks with antihypertensive drugs and antidiabetes drugs (blood sugar medications) by potentially lowering blood pressure or blood sugar too far.
Beet root extract can Moderately affect how your body processes certain medications through the CYP3A4 enzyme pathway, and may Minor-level affect blood pressure and another enzyme pathway (CYP1A2). Russian tarragon herb extract carries Moderate interactions with CNS depressants (sedating drugs), blood thinners and antiplatelet drugs, and monoamine oxidase inhibitors (a class of antidepressants).
We could not check chloride for interactions — we hold no data on it. Altogether, these interactions span 1,168 individual medications.
Check your exact medications with the search tool on this page before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Insane Veinz Strawberry Lemonade?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Insane Veinz Strawberry Lemonade interact with 1,167 drugs. Click any drug to see the details.
4 of the 6 ingredients in Insane Veinz Strawberry Lemonade interact with drugs. Each result below shows which ingredient is responsible. Beet Root Extract Russian Tarragon Herb Extract Agmatine Sulfate Sodium
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Russian Tarragon Herb ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Evidence from in vitro research suggests that tarragon extract inhibits platelet aggregation and adhesion.
Read the full Russian Tarragon Herb Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Russian Tarragon Herb ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Evidence from in vitro research suggests that tarragon extract inhibits platelet aggregation and adhesion.
Read the full Russian Tarragon Herb Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Agmatine SulfateAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Agmatine Sulfate + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Insane Veinz Strawberry Lemonade — through 3 ingredients. Tap an ingredient for the detail:
Agmatine SulfateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Agmatine Sulfate + Acebutolol interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acebutolol interactionBeet Root ExtractAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet Root Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Russian Tarragon Herb ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Evidence from in vitro research suggests that tarragon extract inhibits platelet aggregation and adhesion.
Read the full Russian Tarragon Herb Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Russian Tarragon Herb ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg.
Read the full Russian Tarragon Herb Extract + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Insane Veinz Strawberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Russian Tarragon Herb ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Evidence from in vitro research suggests that tarragon extract inhibits platelet aggregation and adhesion.
Read the full Russian Tarragon Herb Extract + Acetaminophen, Aspirin interactionBeet Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Insane Veinz Strawberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract + Acetaminophen, Aspirin, Caffeine interactionRussian Tarragon Herb ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Evidence from in vitro research suggests that tarragon extract inhibits platelet aggregation and adhesion.
Read the full Russian Tarragon Herb Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Insane Veinz Strawberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionRussian Tarragon Herb ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg.
Read the full Russian Tarragon Herb Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Insane Veinz Strawberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Russian Tarragon Herb ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg.
Read the full Russian Tarragon Herb Extract + Acetaminophen, Butalbital, Codeine interactionBeet Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Insane Veinz Strawberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Russian Tarragon Herb ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg.
Read the full Russian Tarragon Herb Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionBeet Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Insane Veinz Strawberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionRussian Tarragon Herb ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg.
Read the full Russian Tarragon Herb Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Insane Veinz Strawberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Russian Tarragon Herb ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg.
Read the full Russian Tarragon Herb Extract + Acetaminophen, Caffeine, Codeine interactionBeet Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Insane Veinz Strawberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Russian Tarragon Herb ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg.
Read the full Russian Tarragon Herb Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionBeet Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Insane Veinz Strawberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionRussian Tarragon Herb ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg.
Read the full Russian Tarragon Herb Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Insane Veinz Strawberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionRussian Tarragon Herb ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg.
Read the full Russian Tarragon Herb Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Insane Veinz Strawberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Beet Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Insane Veinz Strawberry Lemonade with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Beet Root Extract
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.
Antihypertensive Drugs
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.
Russian Tarragon Herb Extract
Anticoagulant/Antiplatelet Drugs
Evidence from in vitro research suggests that tarragon extract inhibits platelet aggregation and adhesion. Theoretically, tarragon might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
Cns Depressants
Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg. Theoretically, concomitant use of tarragon with CNS depressants, including antihistamines, barbiturates, benzodiazepines, and tricyclic antidepressants, may increase sedative and other adverse effects.
Monoamine Oxidase Inhibitors (Maois)
In vitro research suggests that tarragon extract inhibits monoamine oxidase (MAO)-A and MAO-B enzymes. Theoretically, concomitant use with MAOIs might increase the effects and adverse effects associated with MAOIs.
Agmatine Sulfate
Antidiabetes Drugs
Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggest that agmatine has mild hypoglycemic effects.
Antihypertensive Drugs
Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that agmatine can modestly decrease heart rate and blood pressure.
Sodium
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Brand information
Manufacturer and brand details for Insane Veinz Strawberry Lemonade, from the product label.
Insane Labz
See all Insane Labz products- Name
- Insane Labz
- Street Address
- 675 East Highway 43
- City
- Harrison
- State
- AR
- ZipCode
- 72601
Insane Veinz Strawberry Lemonade by Insane Labz: Common Questions
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The Full Monographs Behind Insane Veinz Strawberry Lemonade’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sodium
Interacts with 205 drugsSodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...
Read the full Sodium monograph → Herb & supplement monographBetaine Anhydrous
Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and as a prescription medicine for a rare gen...
Read the full Betaine Anhydrous monograph → Herb & supplement monographAgmatine
Interacts with 258 drugsAgmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most of its claimed benefits is limited and...
Read the full Agmatine monograph → Herb & supplement monographBeet
Interacts with 861 drugsBeet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...
Read the full Beet monograph → Herb & supplement monographTarragon
Interacts with 359 drugsTarragon is a flavorful culinary herb that has been used in traditional medicine for digestion, sleep, and other complaints, but solid human evidence for any health benefit is lacking. Amoun...
Read the full Tarragon monograph →Sources & How We Checked
Insane Veinz Strawberry Lemonade's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 75 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sodium 38 references
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- Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
- Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
- Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
- Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
- Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
- Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
- Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
- Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
- D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
- Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
- Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
- Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
- Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
- Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
- Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
- Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
- O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
- Poggio R, Gutierrez L, Matta MG, Elorriaga N, Irazola V, Rubinstein A. Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies. Public Health Nutr. 2015;18(4):695-704. PubMed
- Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
- Mahtani KR, Heneghan C, Onakpoya I, et al. Reduced Salt Intake for Heart Failure: A Systematic Review. JAMA Intern Med. 2018 Dec 1;178(12):1693-1700. PubMed
- Yancy CW. Sodium Restriction in Heart Failure: Too Much Uncertainty-Do the Trials. JAMA Intern Med. 2018 Dec 1;178(12):1700-1701. PubMed
- He FJ, Campbell NRC, Ma Y, MacGregor GA, Cogswell ME, Cook NR. Errors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health. Int J Epidemiol. 2018;47(6):1784-1795. PubMed
- Murthy K, Ondrey GJ, Malkani N, et al. THE EFFECTS OF HYPONATREMIA ON BONE DENSITY AND FRACTURES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Endocr Pract. 2019;25(4):366-378. PubMed
- Messerli FH, Hofstetter L, Syrogiannouli L, et al. Sodium intake, life expectancy, and all-cause mortality. Eur Heart J 2021;42(21):2103-2112. PubMed
- Graudal NA, Hubeck-Graudal T, Jurgens G. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride. Cochrane Database Syst Rev 2020;12(12):CD004022. PubMed
- Giatti S, Santos RB, Aielo AN, et al. Association of sodium with obstructive sleep apnea. The ELSA-Brasil study. Ann Am Thorac Soc 2021;18(3):502-510. PubMed
- Nan X, Lu H, Wu J, et al. The interactive association between sodium intake, alcohol consumption and hypertension among elderly in northern China: a cross-sectional study. BMC Geriatr 2021;21(1):135. PubMed
- Kyozuka H, Fukusda T, Murata T, et al. Impact of preconception sodium intake on hypertensive disorders of pregnancy: The Japan Environment and Children's study. Pregnancy Hypertens 2021;23:66-72. PubMed
- Zhao L, Ogden CL, Yang Q, et al. Association of usual sodium intake with obesity among US children and adolescents, NHANES 2009-2016. Obesity (Silver Spring) 2021;29(3):587-594. PubMed
- Ma Y, He FJ, Sun Q, et al. 24-Hour urinary sodium and potassium excretion and cardiovascular risk. N Engl J Med 2022;386(3):252-263. PubMed
- Liu J, Yang X, Zhang P, et al. Association of urinary sodium excretion and left ventricular hypertrophy in people with type 2 diabetes mellitus: A cross-sectional study. Front Endocrinol (Lausanne) 2021;12:728493. PubMed
- Filippini T, Malavolti M, Whelton PK, Vinceti M. Sodium intake and risk of hypertension: A systematic review and dose-response meta-analysis of observational cohort studies. Curr Hypertens Rep 2022;24(5):133-144. PubMed
- Wang DD, Li Y, Nguyen XT, et al. Dietary sodium and potassium intake and risk of non-fatal cardiovascular diseases: The million veteran program. Nutrients 2022;14(5):1121. PubMed
- Kwak JH, Park CH, Eun CS, et al. The associations of dietary intake of high sodium and low zinc with gastric cancer mortality: A prospective cohort study in Korea. Nutr Cancer 2022;74(10):3501-3508. PubMed
- George S, Maiti R, Mishra BR, Jena M, Mohapatra D. Effect of regulated add-on sodium chloride intake on stabilization of serum lithium concentration in bipolar disorder: A randomized controlled trial. Bipolar Disord 2023;25(1):66-75. PubMed
- Zhou TL, Schütten MTJ, Kroon AA, et al. Urinary Sodium Excretion and Salt Intake Are Not Associated With Blood Pressure Variability in a White General Population. J Am Heart Assoc 2023;12(1):e026578. PubMed
Betaine Anhydrous 11 references
- Cystadane (betaine anhydrous for oral solution) Package insert. Orphan Medical, Inc. Minnetonka, MN. November 2005.
- Abdelmalek MF, Angulo P, Jorgensen RA, et al. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 2001;96:2711-7.. PubMed
- Schwab U, Torronen A, Toppinen L, et al. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr 2002;76:961-7. PubMed
- McGregor DO, Dellow WJ, Robson RA, et al. Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure. Kidney Int 2002;61:1040-6. PubMed
- Olthof MR, van Vliet T, Verhoef P, et al. Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans. PloS Med 2005;2:e135. PubMed
- Knopman, D. and Patterson, M. An open-label, 24-week pilot study of the methyl donor betaine in Alzheimer disease patients. Alzheimer Dis.Assoc.Disord. 2001;15(3):162-165. PubMed
- Moat, S. J., Madhavan, A., Taylor, S. Y., Payne, N., Allen, R. H., Stabler, S. P., Goodfellow, J., McDowell, I. F., Lewis, M. J., and Lang, D. High- but not low-dose folic acid improves endothelial function in coronary artery disease. Eur J Clin Invest 2 PubMed
- Abdelmalek, M. F., Sanderson, S. O., Angulo, P., Soldevila-Pico, C., Liu, C., Peter, J., Keach, J., Cave, M., Chen, T., McClain, C. J., and Lindor, K. D. Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial. Hepa PubMed
- Ashtary-Larky D, Bagheri R, Ghanavati M, et al. Effects of betaine supplementation on cardiovascular markers: a systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2021 Mar 25:1-18. PubMed
- Zawieja EE, Zawieja B, Chmurzynska A. Betaine supplementation moderately increases total cholesterol levels: a systematic review and meta-analysis. J Diet Suppl. 2021;18(1):105-117. PubMed
- Imbard A, Toumazi A, Magréault S, et al. Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial. Orphanet J Rare Dis 2022;17(1):417. PubMed
Agmatine 3 references
- Piletz JE, Aricioglu F, Cheng JT, et al. Agmatine: clinical applications after 100 years in translation. Drug Discov Today 2013;18(17-18):880-93. PubMed
- Keynan O, Mirovsky Y, Dekel S, Gilad VH, Gilad GM. Safety and efficacy of dietary agmatine sulfate in lumbar disc-associated radiculopathy. An open-label, dose-escalating study followed by a randomized, double-blind, placebo-controlled trial. Pain Med 201 PubMed
- Shopsin B. The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study. Acta Neuropsychiatr 2013;25(2):113-8. PubMed
Beet 14 references
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
- Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
- Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
- Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
- Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
- Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
- Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
- Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
- Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
- Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
- Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed
Tarragon 9 references
- Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
- Yazdanparast, R. and Shahriyary, L. Comparative effects of Artemisia dracunculus, Satureja hortensis and Origanum majorana on inhibition of blood platelet adhesion, aggregation and secretion. Vascul.Pharmacol 2008;48(1):32-37. PubMed
- Sayyah, M., Nadjafnia, L., and Kamalinejad, M. Anticonvulsant activity and chemical composition of Artemisia dracunculus L. essential oil. J Ethnopharmacol. 2004;94(2-3):283-287. PubMed
- Vasil'ev, E. D., Il'nitskaia, S. I., Nikitenko, E. V., and Kaledin, V. I. [Age- and sex-related differences in sensitivity to hepatotoxic action of estragole in mice]. Ross.Fiziol.Zh.Im I.M.Sechenova 2005;91(9):1066-1070.
- Shahriyary, L. and Yazdanparast, R. Inhibition of blood platelet adhesion, aggregation and secretion by Artemisia dracunculus leaves extracts. J Ethnopharmacol. 11-1-2007;114(2):194-198. PubMed
- Drinkwater, N. R., Miller, E. C., Miller, J. A., and Pitot, H. C. Hepatocarcinogenicity of estragole (1-allyl-4-methoxybenzene) and 1'-hydroxyestragole in the mouse and mutagenicity of 1'-acetoxyestragole in bacteria. J Natl.Cancer Inst. 1976;57(6):1323-
- Kaledin, V. I., Pakharukova, M. Y., Pivovarova, E. N., Kropachev, K. Y., Baginskaya, N. V., Vasilieva, E. D., Ilnitskaya, S. I., Nikitenko, E. V., Kobzev, V. F., and Merkulova, T. I. Correlation between hepatocarcinogenic effect of estragole and its infl
- de Pradier E. A trial of a mixture of three essential oils in the treatment of postoperative nausea and vomiting. International Journal of Aromatherapy 2006;16(1):15-20. DOI
- Aydin T, Akincioglu H, Gumustas M, Gulcin I, Kazaz C, Cakir A. Human monoamine oxidase (hMAO) A and hMAO B inhibitors from Artemisia dracunculus L. herniarin and skimmin: human mononamine oxidase A and B inhibitors from A. dracunculus L. Z Naturforsch C J
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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