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Dietary supplement

Iodine+ Ingredients & Drug Interactions

by Codeage

Liquid Category: Mineral
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Iodine+ is a dietary supplement by Codeage with 1 active ingredient. Its ingredients are commonly taken for preventing iodine deficiency, supporting thyroid hormone production, general energy and metabolism support.Based on those ingredients, 7 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Iodine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Iodine+ by Codeage

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Codeage Iodine+ is a single-ingredient liquid supplement containing iodine. The product also includes distilled water, glycerin, and citric acid as inactive ingredients (the excipients that make up the liquid base).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports healthy thyroid function.
  • We looked for evidence on: Iodine deficiency, Hyperthyroidism, Thyroid cancer, Thyroid storm, Hypothyroidism, Goiter — and 1 related terms.
  • The strongest evidence on file: Iodine is rated "Likely Effective" for Iodine deficiency (Natural Medicines).
  • Also on file: Iodine is rated "Possibly Effective" for Thyroid storm.
  • Also on file: Iodine is rated "Insufficient Reliable Evidence To Rate" for Thyroid cancer, Hyperthyroidism.

Iodine is likely effective for preventing thyroid problems from radiation exposure and for correcting iodine deficiency. It may also help with oral sores (oral mucositis) and gum disease (periodontitis), though the evidence for those uses is less firm.

The dose and form of this product matter for how well it works — talk with your doctor or pharmacist about whether this particular supplement is right for your situation.

The evidence, ingredient by ingredient Iodine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Iodine in normal dietary amounts is well tolerated. High doses, though, can cause thyroid problems — including both overactive and underactive thyroid — along with nausea, diarrhea, headache, metallic taste, and rarely skin reactions or allergic responses.

In pregnancy, you do need iodine, but only the amount your doctor recommends; avoid high-dose products. Some iodine passes into breast milk, so follow your doctor's guidance while breastfeeding.

If you've ever had a bad reaction to iodine-containing drugs or foods (beyond a shellfish allergy), let your healthcare provider know before taking this.

Side effects, ingredient by ingredient Iodine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Iodine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 7 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Codeage Iodine+, check with your doctor or pharmacist if you take lithium, any antithyroid drug (like propylthiouracil or methimazole), or amiodarone for heart rhythm. All three have Moderate interactions with iodine and require thyroid-function monitoring if combined.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Codeage Iodine+ is useful if you're iodine-deficient or need it for radiation protection — but only at the dose your doctor advises. If you take lithium, antithyroid drugs, or amiodarone, check with your doctor or pharmacist first; thyroid monitoring may be needed.

Pregnancy and breastfeeding are no-go without medical OK, and high doses can cause thyroid damage, so this isn't a supplement to adjust on your own.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Iodine+, straight from the product label.

Brand Codeage
Barcode (UPC) 853919008427
Net contents 2 Fluid Ounce(s); 59.2 mL
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 298387
Product type Mineral
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Iodine+ by Codeage, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s)
Maximum serving Sizes:
1 Drop(s)
Servings per container
1200
UPC/BARCODE
853919008427
IngredientAmount% DV
Iodine250 mcg167%

Other ingredients: distilled Water, Glycerin, Citric Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Contains high-purity iodine sourced from the earth in the USA.

Minerals

Formulation

Organic, Non-GMO, vegan, gluten free, yeast free, and soy free.

Organic, Non-GMO, vegan, gluten free, yeast free, and soy free.

Organic, Non-GMO, vegan, gluten free, yeast free, and soy free. Contains no artificial coloring.

Supports healthy thyroid function

Certified Organic by MOSA

Precautions

CAUTION: As with any dietary supplement, consult your healthcare practitioner before using this product, especially if you are pregnant, nursing, or are otherwise under medical supervision.

Not intended for those under the age of 18. Keep out of reach of children and pets.

Keep out of reach of children and pets.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

USDA Organic

Suggested/Recommended/Usage/Directions

Suggested use: Take 1 drop, immediately follow with purified water and swallow. Use once daily or as directed by your healthcare provider.

General Statements

Questions? Codeage.com

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Iodine+ by Codeage label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Iodine+ by Codeage

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Servings per container1200 Amounts shown are per serving.

Iodine

Interacts with
7 drugs
250 mcg per serving Form: Nascent Iodine

Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements...

Iodine monograph & interactions

Other (inactive) ingredients: Distilled Water, Glycerin, Citric Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Iodine+ by Codeage Drug Interactions

Want to check YOUR meds against Iodine+?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
7Drugs
7 Moderate

Ingredients driving the most interactions

Iodine 7

Each ingredient & the kinds of drugs it affects

For each ingredient in Iodine+ with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Iodine3 drug types · 7 drugs

Amiodarone (Cordarone)

Combining iodine with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with iodine might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.

Likelihood Probable Evidence D
Antithyroid Drugs

Iodine might alter the effects of antithyroid drugs.
Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking iodine while using antithyroid drugs could alter the effects of the antithyroid drugs.

Likelihood Probable Evidence D
Lithium

Combining iodine with lithium might have additive hypothyroid effects.
Lithium can inhibit thyroid function. Several case reports suggest that concomitant use of lithium and potassium iodide can reduce thyroid function in otherwise healthy adults. Monitor thyroid function.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Iodine+, from the product label.

Codeage

See all Codeage products
Name
Codeage LLC
Street Address
5628 Washington Blvd
City
Los Angeles
State
CA
ZipCode
90016
Web Address
www.codeage.com
Pharmacist Counseling Corner

Iodine+ by Codeage: Common Questions

Does Iodine+ by Codeage interact with any medications?
Yes. Based on its ingredients, Iodine+ has a known interaction with 7 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Iodine+ contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this work for iodine deficiency?
Yes — iodine is likely effective for correcting iodine deficiency. The dose matters, though, so make sure you're using the amount your doctor or pharmacist recommends for your situation.
Can I take this if I'm pregnant?
You do need iodine in pregnancy, but the data shows you should use only the amount your doctor advises and avoid high-dose products. Talk with your doctor about whether this supplement is the right choice for you at the dose it provides.
What are the most common side effects?
At normal doses, iodine is usually well tolerated. Higher amounts can cause nausea, diarrhea, headache, metallic taste, and thyroid problems. Rarely, people have allergic reactions like swelling or hives.
Can I use this while breastfeeding?
Some iodine is needed for your baby, but excess can pass into breast milk. Follow your doctor's guidance on how much to take while nursing.
What is this supplement used for besides iodine deficiency?
Iodine may help with oral sores and gum disease, though the evidence for those uses is less established. It's also likely effective for preventing thyroid damage from radiation exposure.
Is this safe for someone with a shellfish allergy?
Shellfish allergy is usually a reaction to seafood proteins, not iodine itself. However, some people can be sensitive to iodine when taken by mouth. If you've had a bad reaction to iodine-containing medications or supplements before, mention it to your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Iodine+ label
Sources

Sources & How We Checked

Iodine+'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Iodine 26 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
  3. Ghent WR, Eskin BA, Low DA, Hill LP. Iodine replacement in fibrocystic disease of the breast. Can J Surg 1993;36:453-60.
  4. Potassium iodide for nuclear exposure. Pharmacist's Letter/Prescriber's Letter 2001;17(12):171214.
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cabezas C, Bustamante B, Holgado W, Begue RE. Treatment of cutaneous sporotrichosis with one daily dose of potassium iodide. Pediatr Infect Dis J 1996;15:352-4. PubMed
  7. Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
  8. Yarrington CD, Pearce EN. Dietary iodine in pregnancy and postpartum. Clin Obstet Gynecol 2011;54:459-70. PubMed
  9. Goel, S., Mandhani, A., Srivastava, A., Kapoor, R., Gogoi, S., Kumar, A., and Bhandari, M. Is povidone iodine an alternative to silver nitrate for renal pelvic instillation sclerotherapy in chyluria? BJU.Int 2004;94(7):1082-1085. PubMed
  10. Teng, W., Shan, Z., Teng, X., Guan, H., Li, Y., Teng, D., Jin, Y., Yu, X., Fan, C., Chong, W., Yang, F., Dai, H., Yu, Y., Li, J., Chen, Y., Zhao, D., Shi, X., Hu, F., Mao, J., Gu, X., Yang, R., Tong, Y., Wang, W., Gao, T., and Li, C. Effect of iodine int
  11. Crawford, B. A., Cowell, C. T., Emder, P. J., Learoyd, D. L., Chua, E. L., Sinn, J., and Jack, M. M. Iodine toxicity from soy milk and seaweed ingestion is associated with serious thyroid dysfunction. Med J Aust. 10-4-2010;193(7):413-415. PubMed
  12. Ohkuma, M. Molluscum contagiosum treated with iodine solution and salicylic acid plaster. Int J Dermatol. 1990;29(6):443-445. PubMed
  13. Connelly KJ, Boston BA, Pearce EN, Sesser D, Snyder D, Braverman LE, Pino S, LaFranchi SH. Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion. J Pediatr. 2012 Oct;161(4):760-2. PubMed
  14. Kasahara T, Narumi S, Okasora K, Takaya R, Tamai H, Hasegawa T. Delayed onset congenital hypothyroidism in a patient with DUOX2 mutations and maternal iodine excess. Am J Med Genet A. 2013 Jan;161A(1):214-7.
  15. Murcia M, Rebagliato M, Iñiguez C, Lopez-Espinosa MJ, Estarlich M, Plaza B, Barona-Vilar C, Espada M, Vioque J, Ballester F. Effect of iodine supplementation during pregnancy on infant neurodevelopment at 1 year of age. Am J Epidemiol. 2011 Apr 1;173(7):8 PubMed
  16. Sang Z, Wang PP, Yao Z, Shen J, Halfyard B, Tan L, Zhao N, Wu Y, Gao S, Tan J, Liu J, Chen Z, Zhang W. Exploration of the safe upper level of iodine intake in euthyroid Chinese adults: a randomized double-blind trial. Am J Clin Nutr. 2012 Feb;95(2):367-73 PubMed
  17. Speeckaert MM, Speeckaert R, Wierckx K, Delanghe JR, Kaufman JM. Value and pitfalls in iodine fortification and supplementation in the 21st century. Br J Nutr. 2011 Oct;106(7):964-73. PubMed
  18. Yun SE, Kang Y, Bae EJ, Hwang K, Jang HN, Cho HS, Chang SH, Park DJ. Iodine-induced thyrotoxic hypokalemic paralysis after ingestion of Salicornia herbace. Ren Fail. 2014 Apr;36(3):461-3.
  19. Iodine Hypersensitivity. Pharmacist's Letter/Prescriber's Letter 2011; 27(5):270504.
  20. Hammel JA, Selby JC. Pustular eruption in a patient with cancer treated with complementary and alternative medicine. JAMA Dermatology 2017 October; E1. doi: 10.1001/jamadermatol.2017.3749. [Epub ahead of print] PubMed
  21. Gil GS, Smith BW, Guerra JR, Williams WT. Acute Delirium in a Hypothyroid Patient Precipitated by Iodine Supplements Use. Am J Ther. 2018;25(6):e717-e718. PubMed
  22. Hamby T, Kunnel N, Dallas JS, Wilson DP. Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism. J Pediatr Endocrinol Metab. 2018;31(9):1061-1064. PubMed
  23. Censi S, Watutantrige-Fernando S, Groccia G, et al. The Effects of Iodine Supplementation in Pregnancy on Iodine Status, Thyroglobulin Levels and Thyroid Function Parameters: Results from a Randomized Controlled Clinical Trial in a Mild-to-Moderate Iodine
  24. Rovner MS, Wolf BJ, Rubin M, et al. Instillation of 5% Povidone-Iodine Ophthalmic Drops Decreases the Respiratory Rate in Children Undergoing Strabismus Surgery: A Randomized Controlled Trial. J Pediatr Ophthalmol Strabismus. 2019;56(6):378-382. PubMed
  25. Guenezan J, Garcia M, Strasters D, et al. Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2021;147(4):400-401. PubMed
  26. Li F, Wan S, Zhang L, et al. A Meta-Analysis of the Effect of Iodine Excess on the Intellectual Development of Children in Areas with High Iodine Levels in their Drinking Water. Biol Trace Elem Res 2022;200(4):1580-1590. PubMed

See these in context on the Iodine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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