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Dietary supplement

Ionic Cobalt Ingredients & Drug Interactions

by Good State

Ionic Cobalt label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ionic Cobalt against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ionic Cobalt is a dietary supplement by Good State with 2 active ingredients. Its ingredients are commonly taken for anemia (historically), part of vitamin b12 nutrition, general 'energy' tonics (unproven).Based on those ingredients, 257 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fulvic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Ionic Cobalt by Good State

Ask about any prescription or over-the-counter medication and we check it for interactions with Ionic Cobalt by Good State — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Ionic Cobalt by Good State

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Ionic Cobalt contains 2 active ingredients: cobalt and fulvic acid. Cobalt is a mineral your body uses as part of vitamin B12, though inorganic cobalt supplements (like this one) have no established benefit.

Fulvic acid is an organic compound derived from soil and decomposed plant matter. The product also contains water and sorbic acid as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: healthy red blood cells and energy.
  • We looked for evidence on: Fatigue, anemia, vitamin B12 deficiency, nerve health.
  • The closest evidence on file: Fulvic Acid is rated "Insufficient Reliable Evidence To Rate" for Fatigue (Natural Medicines).

The evidence we hold doesn't establish that this product works for any condition. Fulvic acid has been studied for respiratory tract infections, lead toxicity, eczema, fatigue, and hay fever, but the data isn't strong enough to rate it effective for any of those uses.

No effectiveness data exists for cobalt as a supplement.

The evidence, ingredient by ingredient Cobalt Fulvic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 1 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cobalt is generally well tolerated in small amounts for up to 90 days, but the safety data advises against it. Taking cobalt long-term or in high doses may cause serious problems including heart muscle disease, hearing loss, and vision loss — even reversible blindness and deafness have been reported in rare cases.

People on a low-protein diet, those with a thiamine deficiency, or those with low thyroid function appear to be at higher risk. Fulvic acid appears to be tolerated in the short term, though high-quality safety data in humans is limited; a small number of trial participants experienced headache, diarrhea, or sore throat.

One rare serious adverse effect called Kashin-Beck bone disease has been reported. The safety data advises against cobalt during pregnancy because of toxicity concerns and lack of safety data, and advises against it while breastfeeding — rely on vitamin B12 instead.

There isn't enough safety information for fulvic acid during pregnancy or while breastfeeding; talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Cobalt Fulvic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Fulvic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 257 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check with your doctor or pharmacist if you use blood thinners (anticoagulants or antiplatelet drugs), immunosuppressants, or thyroid hormone therapy. Fulvic acid may reduce how well blood thinners work and interfere with thyroid and immune medication, all at Moderate severity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Inorganic cobalt supplements have no proven benefit and carry a real risk of serious harm with long-term use or higher doses, so they're generally not recommended. Fulvic acid's effectiveness for any condition isn't established in our data, and it can interfere with blood thinners, immunosuppressants, and thyroid medications.

If you take any of those drugs — or if you're pregnant or breastfeeding — talk with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ionic Cobalt, straight from the product label.

Brand Good State
Barcode (UPC) 857515003046
Net contents 8 fl. Oz.; 240 mL
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 229159
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ionic Cobalt by Good State, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.25 mL
Maximum serving Sizes:
2.5 mL
Servings per container
96
UPC/BARCODE
857515003046
IngredientAmount% DV
Cobalt500 mcg--
Fulvic Acid2 mg--

Other ingredients: double reverse osmosis Water, Ionic Cobalt, Sorbic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Cobalt can be beneficial for healthy red blood cells, nerves, nerve protection, digestive, energy, hormones, blood circulation, growth rate and more.

Good State ionic minerals have been known for their high bioavailability rate while others can be extremely low. Mineral can be described in Picometer, Nanometer, or Angstorm in size.

General Statements

~Good State update~ Ionic Man (#147) & Ionic Woman (#146) now available

Note - Cobalt benefits and/or deficiency symptoms are generic for the mineral. No product claims are being made or implied. Research is ongoing.

100% satisfaction guaranteed

FBA USA

Natural 500 ppm

Give your body what it needs!

Ionic minerals Completely absorbable Nano ionic supplements

Professional grade

X000E02MUX

Health Solution

Formulation

Contains no sugars, soy, GMO, dairy, fish, gluten, starch, artificial flavors, colors, preservatives, or animal by-products and is hypoallergenic.

Suitable for vegetarians.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommended Dosage: Adults: 2.5ml (1/2 cap) daily in water or juice as maintenance once per day. Children under 12 use 1/2 adult dose. Use more if needed or as recommended by your health care professional.

Precautions

Do not use if tamper evident seal is broken or missing.

Caution: Keep out of reach of children.

Always speak with your physician before using any dietary supplement.

Storage

For freshness, keep refrigerated after opening or in cool dark place.

Seals/Symbols

Made in USA GMP Good Manufacturing Practices

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ionic Cobalt by Good State label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ionic Cobalt label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ionic Cobalt by Good State

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1.25 mL Dosage formLiquid Servings per container96 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Cobalt

No known
interactions
500 mcg per serving

Cobalt is a trace element that the body only needs as part of vitamin B12 (cobalamin); there is no proven reason to take inorganic cobalt supplements,...

Cobalt monograph & interactions

Fulvic Acid

Interacts with
257 drugs
2 mg per serving

Fulvic acid is a natural compound formed when plants and microbes break down in soil, and it is sold as a supplement for energy, gut, and overall well...

Fulvic Acid monograph & interactions

Other (inactive) ingredients: Double reverse osmosis Water, Ionic Cobalt, Sorbic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ionic Cobalt by Good State Drug Interactions

Want to check YOUR meds against Ionic Cobalt?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
257Drugs
257 Moderate

Ingredients driving the most interactions

Fulvic Acid 257

Individual Drug Interactions

The ingredients in Ionic Cobalt interact with 257 drugs. Click any drug to see the details.

1 of the 2 ingredients in Ionic Cobalt interact with drugs. Each result below shows which ingredient is responsible. Fulvic Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in Ionic Cobalt with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Fulvic Acid3 drug types · 257 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
In vitro evidence shows that fulvic acid, formed from the oxidation and polymerization of protocatechuic acid, can shorten prothrombin time in human plasma, increasing the risk of clot formation.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Animal research shows that fulvic acid stimulates immune function.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, taking fulvic acid with thyroid hormone therapy might interfere with the ability to normalize thyroid function.
Animal research shows that fulvic acid increases the plasma level of thyroid-stimulating hormone (TSH) and decreases the thyroxine (T4):triiodothyronine (T3) ratio.

Likelihood Possible Evidence D
Fulvic Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ionic Cobalt, from the product label.

Good State

Name
GoodState, Inc.
Street Address
435 W Pennsylvania Ave
City
Fort Washington
State
PA
ZipCode
19034
Phone Number
1-866-227-6097
Web Address
www.GoodState.com
Pharmacist Counseling Corner

Ionic Cobalt by Good State: Common Questions

Does Ionic Cobalt by Good State interact with any medications?
Yes. Based on its ingredients, Ionic Cobalt has a known interaction with 257 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ionic Cobalt contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is fulvic acid and what does it do?
Fulvic acid is an organic compound from decomposed plant matter in soil. Our data shows insufficient evidence that it works for respiratory infections, lead toxicity, eczema, fatigue, or hay fever, so we can't say it's effective for any established use.
Is cobalt safe to take long-term?
No. Inorganic cobalt supplements have no proven benefit and can cause serious toxicity. Long-term use or high doses may cause heart muscle disease, hearing loss, and vision loss — even permanent blindness has been reported. The safety data advises against cobalt supplements.
Can I take this while pregnant or breastfeeding?
No. The cobalt in this product should be avoided during pregnancy and breastfeeding due to toxicity concerns and lack of safety data. There also isn't enough safety information for fulvic acid in pregnancy or while breastfeeding. Talk with your doctor or pharmacist for personalized advice.
What side effects might I get from this product?
Cobalt in small doses seems well tolerated for up to 90 days, but long-term or higher doses can cause serious effects like heart problems, hearing loss, and vision loss. Fulvic acid may cause headache, diarrhea, or sore throat in some people, and rarely Kashin-Beck bone disease.
Can I take this if I'm on a blood thinner?
No — talk with your doctor or pharmacist first. Fulvic acid may reduce how well blood thinners work and increase your clot risk. This is a Moderate severity interaction, so your prescriber needs to know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ionic Cobalt label
Go deeper

The Full Monographs Behind Ionic Cobalt’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cobalt

Cobalt is a trace element that the body only needs as part of vitamin B12 (cobalamin); there is no proven reason to take inorganic cobalt supplements, and doing so can be harmful. If you nee...

Read the full Cobalt monograph → Herb & supplement monograph

Fulvic Acid

Interacts with 257 drugs

Fulvic acid is a natural compound formed when plants and microbes break down in soil, and it is sold as a supplement for energy, gut, and overall wellness. Human research is very limited, so...

Read the full Fulvic Acid monograph →
Sources

Sources & How We Checked

Ionic Cobalt's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cobalt 11 references
  1. Packer M. Cobalt cardiomyopathy: a critical reappraisal in light of a recent resurgence. Circ Heart Fail 2016;9(12). pii: e003604. PubMed
  2. Adams TN, Butt YM, Batra K, Glazer CS. Cobalt related interstitial lung disease. Respir Med 2017;129:91-7. PubMed
  3. Lim CA, Khan J, Chelva E, Khan R, Unsworth-Smith T. The effect of cobalt on the human eye. Doc Ophthalmol 2015;130(1):43-8. PubMed
  4. Guarneri F, Guarneri C, Cannavò SP. Nail-art and cobalt allergy. Contact Dermatitis 2010;62(5):320-1. PubMed
  5. Fowler JF Jr. Cobalt. Dermatitis 2016;27(1):3-8.
  6. Zajdel NJ, Smith WA, Taintor AR, Jacob SE, Olasz EB. Chemical tattoo treatment leading to systemic cobalt hypersensitivity. Skinmed 2017;15(3):221-2.
  7. Bregnbak D, Opstrup MS, Jellesen MS, Johansen JD, Thyssen JP. Allergic contact dermatitis caused by cobalt in leather - clinical cases. Contact Dermatitis 2017;76(6):366-8. PubMed
  8. Simonsen AB, Friis UF, Johansen JD, Zachariae C, Sloth JJ, Thyssen JP. Occupational allergic contact dermatitis caused by cobalt in machine oil. Contact Dermatitis 2019;80(1):59-61. PubMed
  9. Paustenbach DJ, Galbraith DA, Finley BL. Interpreting cobalt blood concentrations in hip implant patients. Clin Toxicol (Phila) 2014;52(2):98-112. PubMed
  10. Zywiel MG, Cherian JJ, Banerjee S, et al. Systemic cobalt toxicity from total hip arthroplasties: review of a rare condition Part 2. measurement, risk factors, and step-wise approach to treatment. Bone Joint J 2016;98-B(1):14-20. PubMed
  11. Catalani S, Rizzetti MC, Padovani A, Apostoli P. Neurotoxicity of cobalt. Hum Exp Toxicol 2012;31(5):421-37. PubMed

See these in context on the Cobalt monograph →

Fulvic Acid 3 references
  1. Lu, FJ. Arsenic as a promoter in the effect of humic substances on plasma prothrombin time in vitro. Thromb Res 6-15-1990;58(6):537-541. PubMed
  2. Vucskits, AV, Hullar, I, Bersenyi, A, Andrasofszky, E, Kulcsar, M, Szabo, J. Effect of fulvic and humic acids on performance, immune response and thyroid function in rats. J Anim Physiol Anim Nutr (Berl) 2010;94(6):721-728. PubMed
  3. Gandy JJ, Meeding JP, Snyman JR, et al. Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid. Clin Pharmacol. 2012;4:7-11. PubMed

See these in context on the Fulvic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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