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Dietary supplement

Complete Essentials Concentrate Ingredients & Drug Interactions

by Complete H2O Minerals

Complete Essentials Concentrate label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Complete Essentials Concentrate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Complete Essentials Concentrate is a dietary supplement by Complete H2O Minerals with 9 active ingredients. Its ingredients are commonly taken for preventing or treating copper deficiency, supporting red blood cell formation, bone and connective tissue health.Based on those ingredients, 521 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Selenium, Vanadium, Chromium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Complete Essentials Concentrate by Complete H2O Minerals

Ask about any prescription or over-the-counter medication and we check it for interactions with Complete Essentials Concentrate by Complete H2O Minerals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Complete Essentials Concentrate by Complete H2O Minerals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 9 of its 9 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Complete Essentials Concentrate delivers 9 active mineral ingredients: copper, manganese, chromium, boron, selenium, cobalt, vanadium, molybdenum, and indium. Each plays a potential nutritional role — copper helps with deficiency; manganese supports deficiency correction; chromium may assist with blood sugar control; boron supports bone and vaginal health; selenium protects against deficiency; and vanadium and molybdenum address deficiency states where they occur.

The product is a liquid, making it easy to mix into water or beverages. The inactive ingredients are purified water and mineral chloride compounds (the salt forms of the minerals themselves), which serve as the delivery vehicle for the active elements.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support immune system and body systems.
  • We looked for evidence on: Cardiovascular disease (CVD), Hypothyroidism, Iron deficiency anemia, General wellness, Nutritional supplementation, Trace mineral deficiency — and 1 related terms.
  • The closest evidence on file: Selenium is rated "Possibly Ineffective" for Cardiovascular disease (CVD) (Natural Medicines).
  • Also on file: Copper is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD).
  • Also on file: Selenium is rated "Insufficient Reliable Evidence To Rate" for Hypothyroidism.

Evidence for these minerals varies widely. Copper is likely effective for copper deficiency but possibly ineffective for Alzheimer's disease.

Manganese is effective for manganese deficiency; evidence for allergic rhinitis, osteoporosis, and other conditions is insufficient. Chromium is likely effective for chromium deficiency and possibly effective for type 2 diabetes, though possibly ineffective for prediabetes and several other conditions.

Boron is likely effective for boron deficiency and possibly effective for vaginal yeast infections and radiation skin damage. Selenium is likely effective for selenium deficiency and possibly effective for Kashin-Beck disease and pre-eclampsia, but possibly ineffective for high cholesterol.

Vanadium is likely effective for vanadium deficiency; evidence for diabetes and athletic performance is insufficient. Molybdenum is likely effective for molybdenum deficiency; evidence for acne, anemia, and other conditions is insufficient.

Indium is listed as effective only for cancer diagnosis (imaging), not as a nutritional supplement. Cobalt has no effectiveness ratings in our data.

The evidence, ingredient by ingredient Copper Manganese Chromium Boron Selenium Cobalt Vanadium Molybdenum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 9 of the 9 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 9 of 9.
  • General safety write-ups exist for 9 of 9.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients are generally well tolerated at normal dietary and supplement doses. Copper is safe in food and standard supplements but excess can be toxic; pregnancy requires staying within recommended amounts.

Manganese is safe in normal dietary amounts, though high-dose supplements carry risk of Parkinson-like neurological symptoms; manganese intoxication is rare but serious and can cause liver damage. Chromium is usually well tolerated at typical supplement doses; gastrointestinal irritation, headaches, and mood changes occur most commonly, and rare cases of kidney and liver damage have been reported.

Boron is safe below 20 mg daily; chronic high doses can cause skin problems and hair loss, and acute poisoning in children causes severe nausea and vomiting. Selenium is safe below 400 mcg daily; excess causes hair loss, nail changes, nausea, fatigue, and in severe cases multi-organ failure.

Cobalt long-term or in high doses may cause heart damage, hearing loss, and vision loss and is generally not recommended. Vanadium is well tolerated below 1.8 mg daily; higher doses cause gastrointestinal upset and can damage kidneys with long-term use.

Molybdenum is safe at food levels; one case report of high supplemental doses caused seizures and psychosis. Indium lacks reliable safety data and is not an essential nutrient.

Side effects, ingredient by ingredient Copper Manganese Chromium Boron Selenium Cobalt Vanadium Molybdenum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 9 matched ingredients can interact with medications — Manganese, Vanadium, Copper, Chromium, Selenium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 521 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check these medication types with your pharmacist: penicillamine (Moderate severity — separate doses by 2 hours), antidiabetes drugs and insulin (Moderate — increased low blood sugar risk), blood thinners and antiplatelet drugs (Moderate — increased bleeding risk), tetracycline and quinolone antibiotics (Moderate — reduced antibiotic absorption), levothyroxine thyroid hormone (Moderate — reduced absorption), antipsychotic drugs (Moderate — increased toxicity risk), barbiturate sedatives (Moderate — prolonged sedation), immunosuppressants (Moderate — reduced effectiveness), warfarin (Moderate — possible interference), and NSAIDs, aspirin, niacin, or oral contraceptives (Minor — various effects on mineral levels). If none of your medications appear in that list, no interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're deficient in one or more of these minerals, this product may help fill that gap — especially copper, manganese, chromium, boron, selenium, vanadium, or molybdenum. However, if you take prescription medications — particularly penicillamine, antibiotics, diabetes drugs, thyroid hormone, blood thinners, antipsychotics, sedatives, or immunosuppressants — you need to check your exact medications with the tool below before starting.

Talk to your pharmacist before adding this to your routine, especially if you're pregnant, breastfeeding, or have liver or kidney concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 9 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Complete Essentials Concentrate, straight from the product label.

Brand Complete H2O Minerals
Barcode (UPC) 188671000878
Net contents 32 Ounce(s); 1 Quart(s); 946 mL
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 252103
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Complete Essentials Concentrate by Complete H2O Minerals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 mL
Maximum serving Sizes:
15 mL
Servings per container
64
UPC/BARCODE
188671000878
IngredientAmount% DV
Copper172 mcg15%
Manganese115 mcg1%
Chromium115 mg45%
Boron12 mcg1%
Selenium115 mcg45%
Cobalt14 mcg50%
Vanadium12 mcg120%
Molybdenum23 mcg25%
Indium46 mcg--

Other ingredients: purified Water, Boron Chloride, Chromium Chloride, Cobalt Chloride, Selenium Chloride, Indium Chloride, Copper Chloride, Manganese Chloride, Molybdenum Chloride, Vanadium Chloride

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

This special blend of very important minerals will offer support to many of the Body's systems, including the immune system. Our Complete Essentials mineral water is a unique blend of 10 essential trace minerals in combination with our Calcium-Magnesium mineral water, and our Potassium-Zinc mineral water gives you a well balanced mineral supplement.

Formulation

With our special breakdown process all of our minerals have a very high absorption rate not just in the bloodstream but all the ways down the inter cellular part of the cells.

In processing, FDA & GMP guidelines are observed and strictly followed.

Complete H2O minerals contain no fillers or artificial ingredients.

Suggested/Recommended/Usage/Directions

Mixing instructions: Mix with 8 to 10 ounces of juice or water.

Recommended Dosage: Adults: 1 Tbsp. 15 ml Children: 1 Tsp. 5 ml or as recommended by a healthcare professional.

General Statements

Quality products for a quality life!

FDA Statement of Identity

Dietary Supplement

Storage

For best results, store in a cool, dark place and use within six months.

Precautions

Note: Do not use if tamper seal is broken or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Complete Essentials Concentrate by Complete H2O Minerals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Complete Essentials Concentrate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Complete Essentials Concentrate by Complete H2O Minerals

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size15 mL Dosage formLiquid Servings per container64 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Copper

Interacts with
31 drugs
172 mcg per serving

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...

Copper monograph & interactions

Manganese

Interacts with
83 drugs
115 mcg per serving

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get...

Manganese monograph & interactions

Chromium

Interacts with
178 drugs
115 mg per serving

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...

Chromium monograph & interactions

Boron

No known
interactions
12 mcg per serving

Boron is a trace mineral found in many plant foods and sold as a supplement, mainly promoted for bone, joint, and hormone health. The human evidence f...

Boron monograph & interactions

Selenium

Interacts with
321 drugs
115 mcg per serving

Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who...

Selenium monograph & interactions

Cobalt

No known
interactions
14 mcg per serving

Cobalt is a trace element that the body only needs as part of vitamin B12 (cobalamin); there is no proven reason to take inorganic cobalt supplements,...

Cobalt monograph & interactions

Vanadium

Interacts with
208 drugs
12 mcg per serving

Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athle...

Vanadium monograph & interactions

Molybdenum

No known
interactions
23 mcg per serving

Molybdenum is an essential trace mineral your body needs in tiny amounts to help certain enzymes work. Most people get enough from a normal diet, so s...

Molybdenum monograph & interactions

Indium

No known
interactions
46 mcg per serving

Indium is a metallic chemical element sometimes sold as a liquid 'trace mineral' supplement with bold anti-aging and energy claims, but it is not a re...

Indium monograph & interactions

Other (inactive) ingredients: Purified Water, Boron Chloride, Chromium Chloride, Cobalt Chloride, Selenium Chloride, Indium Chloride, Copper Chloride, Manganese Chloride, Molybdenum Chloride, Vanadium Chloride. These complete the product’s ingredient list but are not active constituents.

Interaction report

Complete Essentials Concentrate by Complete H2O Minerals Drug Interactions

Want to check YOUR meds against Complete Essentials Concentrate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
521Drugs
458 Moderate 63 Minor

Ingredients driving the most interactions

Selenium 321
Vanadium 208
Chromium 178
Manganese 83
Copper 31

Individual Drug Interactions

The ingredients in Complete Essentials Concentrate interact with 521 drugs. Click any drug to see the details.

5 of the 9 ingredients in Complete Essentials Concentrate interact with drugs. Each result below shows which ingredient is responsible. Selenium Vanadium Chromium Manganese Copper

Each ingredient & the kinds of drugs it affects

For each ingredient in Complete Essentials Concentrate with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Selenium6 drug types · 321 drugs

Anticoagulant/Antiplatelet Drugs

Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that taking selenium 10 mcg/kg/day can increase bleeding times by increasing prostacyclin production, which inhibits platelet activity. Other clinical research suggests that taking selenium 75 mcg daily, in combination with ascorbic acid 600 mg, alpha-tocopherol 300 mg, and beta-carotene 27 mg, reduces platelet aggregation.

Likelihood Possible Evidence D
Barbiturates

Theoretically, selenium might prolong the sedating effects of barbiturates.
Laboratory research suggests that selenium can inhibit the hepatic metabolism of barbiturates. Selenium seems to prolong the sedative effect of pentobarbital in animal models.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
In vitro research and preliminary clinical evidence suggests that selenium may stimulate the immune system.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, selenium might interfere with warfarin activity.
Animal research suggests that selenium can increase warfarin activity. Selenium might interact with warfarin by displacing it from albumin binding sites, reducing its metabolism in the liver, or by decreasing production of vitamin K-dependent clotting factors. Selenium can also prolong bleeding times in humans by increasing prostacyclin production, which inhibits platelet activity.

Likelihood Possible Evidence D
Contraceptive Drugs

Contraceptive drugs might increase levels of selenium, although the clinical significance of this effect is unclear.
Some research suggests that oral contraceptives increase serum selenium levels in women taking oral contraceptives; however, other research shows no change in selenium levels. It is suggested that an increase could be due to increased carrier proteins, indicating a redistribution of selenium rather than a change in total body selenium.

Likelihood Possible Evidence B
Niacin

Selenium might reduce the beneficial effects of niacin on high-density lipoprotein (HDL) levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as selenium, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Selenium full monograph & interactions

Vanadium2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that the sodium orthovanadate form of vanadium prolongs clotting time, likely through inhibition of thrombin and factor Xa.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
A few very small clinical studies in patients with type 2 diabetes show that the vanadyl sulfate form of vanadium increases insulin sensitivity and might lower blood glucose levels.

Likelihood Probable Evidence B
Vanadium full monograph & interactions

Chromium5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
Chromium full monograph & interactions

Manganese3 drug types · 83 drugs

Antipsychotic Drugs

Theoretically, the risk for manganese toxicity might increase when taken with antipsychotic drugs.
Hallucinations and behavioral changes have been reported in a patient with liver disease who was taking haloperidol and manganese. Researchers speculate that taking manganese along with haloperidol, phenothiazine-derivatives, or other antipsychotic medications might increase the risk of manganese toxicity in some patients.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, manganese might reduce the absorption of quinolone antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced quinolone absorption have been reported between quinolones and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, manganese might reduce the absorption of tetracycline antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced tetracycline absorption have been reported between tetracyclines and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Manganese full monograph & interactions

Copper2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
Copper full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Complete Essentials Concentrate, from the product label.

Complete H2O Minerals

See all Complete H2O Minerals products
Name
Complete H2O Minerals
Phone Number
1.877.646.3725
Web Address
www.completeh2ominerals.com
Pharmacist Counseling Corner

Complete Essentials Concentrate by Complete H2O Minerals: Common Questions

Does Complete Essentials Concentrate by Complete H2O Minerals interact with any medications?
Yes. Based on its ingredients, Complete Essentials Concentrate has a known interaction with 521 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Complete Essentials Concentrate contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe if I'm pregnant or breastfeeding?
It depends on the ingredient. Copper and selenium are possibly unsafe in pregnancy at high doses; boron, cobalt, and vanadium should be avoided in pregnancy. For manganese, chromium, and molybdenum, small food amounts are fine, but extra supplements should be avoided unless your doctor advises. Indium has no safety data and should be avoided. For breastfeeding, boron and vanadium should be avoided; cobalt and indium lack safety data. Talk with your doctor or pharmacist for personalized guidance.
Can this help with Alzheimer's disease?
No — the copper in this product is possibly ineffective for Alzheimer's disease according to available evidence, so this product is not a suitable choice for that purpose.
What are the most common side effects?
At normal doses, most people tolerate these minerals well. The most common effects — seen rarely — include gastrointestinal upset (nausea, diarrhea, indigestion), headaches, skin rash, and mood changes from chromium or vanadium. Higher doses increase the risk of more serious effects like nerve damage from manganese or hair and nail changes from selenium.
What is cobalt or indium for in this product?
Cobalt has no proven nutritional benefit from inorganic supplements and is not recommended. Indium is not an essential nutrient and is used clinically only for cancer imaging — it has no established benefit as an oral supplement and lacks reliable safety data. Neither belongs in a nutritional product.
Does this work for diabetes or blood sugar control?
Chromium is possibly effective for type 2 diabetes, and vanadium is possibly effective for blood sugar control, but evidence is limited. Boron, selenium, and several other ingredients have insufficient evidence. This should not replace your diabetes medication — always talk to your doctor before adding any supplement to your diabetes routine.
What happens if I take too much?
Excess minerals can be toxic. Manganese and selenium at high levels cause neurological and organ damage. Boron, vanadium, molybdenum, and cobalt can also cause serious harm at high doses. Stick to the product's directions and do not exceed recommended amounts without medical guidance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Complete Essentials Concentrate label
Go deeper

The Full Monographs Behind Complete Essentials Concentrate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Copper

Interacts with 31 drugs

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes work. Most people get enough copper from fo...

Read the full Copper monograph → Herb & supplement monograph

Manganese

Interacts with 83 drugs

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get enough from a normal diet. Supplements m...

Read the full Manganese monograph → Herb & supplement monograph

Chromium

Interacts with 178 drugs

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...

Read the full Chromium monograph → Herb & supplement monograph

Boron

Boron is a trace mineral found in many plant foods and sold as a supplement, mainly promoted for bone, joint, and hormone health. The human evidence for most of these uses is limited or prel...

Read the full Boron monograph → Herb & supplement monograph

Selenium

Interacts with 321 drugs

Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who eat a varied diet get enough, and supple...

Read the full Selenium monograph → Herb & supplement monograph

Cobalt

Cobalt is a trace element that the body only needs as part of vitamin B12 (cobalamin); there is no proven reason to take inorganic cobalt supplements, and doing so can be harmful. If you nee...

Read the full Cobalt monograph → Herb & supplement monograph

Vanadium

Interacts with 208 drugs

Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athletic performance are not well proven, and...

Read the full Vanadium monograph → Herb & supplement monograph

Molybdenum

Molybdenum is an essential trace mineral your body needs in tiny amounts to help certain enzymes work. Most people get enough from a normal diet, so supplements are rarely needed unless a do...

Read the full Molybdenum monograph → Herb & supplement monograph

Indium

Indium is a metallic chemical element sometimes sold as a liquid 'trace mineral' supplement with bold anti-aging and energy claims, but it is not a recognized essential nutrient and there is...

Read the full Indium monograph →
Sources

Sources & How We Checked

Complete Essentials Concentrate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 166 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Copper 11 references
  1. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  2. Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. DOI
  3. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  4. Kozak SF, Inderlied CB, Hsu HY, et al. The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. Diag Microbiol Infect Dis 1998;30:83-7. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50.
  7. Babic Z, Tariba B, Kovacic J, Pizent A, Varnai VM, Macan J. Relevance of serum copper elevation induced by oral contraceptives: a meta-analysis. Contraception. 2013 Jun;87(6):790-800. PubMed
  8. Qui Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: a meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res 2017;177(1):53-63.
  9. Walker-Smith PK, Keith DJ, Kennedy CT, Sansom JE. Allergic contact dermatitis caused by copper. Contact Dermatitis 2016;75(3):186-7. PubMed
  10. Gallentine A. Third-degree burn on the neuropathic lower extremity in a patient with diabetes while wearing a copper-containing compression sock: a case report. Wound Manag Prev 2021;67(12):26-29. DOI
  11. Chung KJ, Chin YM, Wong MS, Sanmugam A, Singaravel S, Nah SA. Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial. J Pediatr Surg 2022;57(2):261-265. PubMed

See these in context on the Copper monograph →

Manganese 21 references
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Chromium 53 references
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Boron 6 references
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Selenium 36 references
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Cobalt 11 references
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Vanadium 15 references
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See these in context on the Vanadium monograph →

Molybdenum 8 references
  1. Chan S, Gerson B, Subramaniam S. The role of copper, molybdenum, selenium, and zinc in nutrition and health. Clin Lab Med 1998;18:673-85. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Rajagopalan KV. Molybdenum: an essential trace element in human nutrition. Annu Rev Nutr 1988;8:401-27. PubMed
  4. Selden AI, Berg NP, Soderbergh A, Bergstrom BE. Occupational molybdenum exposure and a gouty electrician. Occup Med (Lond) 2005;55:145-8. PubMed
  5. Al-Saleh E, Nandakumaran M, Al-Shammari M, Al-Harouny A. Maternal-fetal status of copper, iron, molybdenum, selenium and zinc in patients with gestational diabetes. J Matern Fetal Neonatal Med 2004;16:15-21. PubMed
  6. Koster R, Vieluf D, Kiehn M, et al. Nickel and molybdenum contact allergies in patients with coronary in-stent restenosis. Lancet 2000;356:1895-7. PubMed
  7. Vyskocil A, Viau C. Assessment of molybdenum toxicity in humans. J Appl Toxicol 1999;19:185-92. DOI
  8. Momcilovic, B. A case report of acute human molybdenum toxicity from a dietary molybdenum supplement--a new member of the "Lucor metallicum" family. Arh.Hig.Rada Toksikol. 1999;50(3):289-297. DOI

See these in context on the Molybdenum monograph →

Indium 5 references
  1. Miyaki K, Hosoda K, Hirata M, et al. Biological monitoring of indium by means of graphite furnace atomic absorption spectrophotometry in workers exposed to particles of indium compounds. J Occup Health 2003;45:228-30. PubMed
  2. Indium. Material Safety Data Sheet. Science Lab, October 2005.
  3. Indium In-111 pentetreotide injection (OctreoScan) Package Insert. Curium US LLC, Maryland Heights, MO. 2018. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=93d8f3b2-1216-41dc-a63d-0e812b33891d. Accessed April 25, 2020.
  4. Tsao YC, Fan HY, Luo JJ. Case reports of indium lung disease in Taiwan. J Formos Med Assoc. 2021 Feb;120(2):893-8. PubMed
  5. Yang J, Zhang W, Feng J. Low serum indium levels induce expression disorders of some inflammatory factors. Int Arch Occup Environ Health. 2021 Jan;94(1):23-30. PubMed

See these in context on the Indium monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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