No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Somaplex 2 Cobalt Ingredients & Drug Interactions

by Nestmann

Somaplex 2 Cobalt label
See full label image
Liquid Category: Mineral
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Somaplex 2 Cobalt against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Somaplex 2 Cobalt is a dietary supplement by Nestmann with 1 active ingredient. Its ingredients are commonly taken for anemia (historically), part of vitamin b12 nutrition, general 'energy' tonics (unproven).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Somaplex 2 Cobalt by Nestmann

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: cobaltous sulfate, an inorganic form of cobalt. The liquid formulation also includes water and ethyl alcohol as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Cobalt product and its label doesn't state a use — see Cobalt's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for cobaltous sulfate in our system, so we cannot tell you whether this product is shown to work for any condition.

The evidence, ingredient by ingredient Cobalt

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cobalt appears to be tolerated reasonably well when taken orally in small amounts for short periods (up to 90 days). However, inorganic cobalt supplements have no proven benefit and carry serious safety concerns.

Long-term or high-dose oral use has been linked to cardiomyopathy (a weakening of the heart muscle), hearing loss, and vision loss — effects that are rare but can be permanent. Your risk may be higher if you eat a low-protein diet, are deficient in thiamine (vitamin B1), or have an underactive thyroid.

Allergic skin reactions to cobalt-containing products can also occur in some people. The safety data advises against taking cobalt supplements during pregnancy or while breastfeeding because of toxicity concerns and insufficient safety data.

Side effects, ingredient by ingredient Cobalt

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Run your exact medications through the search tool on this page to be sure.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Inorganic cobalt supplements like this one are not recommended — they offer no proven benefit and carry real risks of heart, hearing, and vision problems over time. If you're concerned about cobalt intake or have a specific reason you're considering this product, talk with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Somaplex 2 Cobalt, straight from the product label.

Brand Nestmann
Net contents 1 fl. Oz.; 29.5 mL
Market status On market
Date entered into DSLD Sep 25, 2013
DSLD ID 25468
Product type Mineral
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Children (All)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Somaplex 2 Cobalt by Nestmann, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.3 mL
Maximum serving Sizes:
0.6 mL
Servings per container
49
IngredientAmount% DV
Cobaltous Sulfate0.059 mg--

Other ingredients: Water, ethyl alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Adults take 20 drops on the tongue or in 1 oz. water two times daily. Children receive 1/2 or less of the adult amount.

Precautions

Tamper Evident: Use this product only if tamper evident ring has not been broken away from base of cap.

General Statements

4893

IONIZED TRACE ELEMENTS

2

>>NESTMANN<<

Made in Germany Nestmann Pharma Zapfendorf/Bamberg

FDA Statement of Identity

SUPPLEMENT

Seals/Symbols

MPI

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Somaplex 2 Cobalt by Nestmann label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Somaplex 2 Cobalt label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Somaplex 2 Cobalt by Nestmann

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.3 mL Dosage formLiquid Servings per container49 Amounts shown are per serving.

Cobaltous Sulfate

No known
interactions
0.059 mg per serving

Cobalt is a trace element that the body only needs as part of vitamin B12 (cobalamin); there is no proven reason to take inorganic cobalt supplements,...

Cobaltous Sulfate monograph & interactions

Other (inactive) ingredients: Water, Ethyl alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Somaplex 2 Cobalt by Nestmann Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Somaplex 2 Cobalt. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Somaplex 2 Cobalt, from the product label.

Nestmann

See all Nestmann products
Name
Marco Pharma Int'l
City
Roseburg
State
OR
ZipCode
97470
Pharmacist Counseling Corner

Somaplex 2 Cobalt by Nestmann: Common Questions

Does Somaplex 2 Cobalt by Nestmann interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Somaplex 2 Cobalt. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Somaplex 2 Cobalt contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does cobaltous sulfate actually work for anything?
We don't hold effectiveness data for cobaltous sulfate in our system. That said, the safety information is clear: inorganic cobalt supplements have no proven benefit, which is one reason they're generally not recommended.
Is it safe to take this long-term?
The data shows cobalt is tolerated reasonably well in small amounts for short periods (up to 90 days), but long-term or high-dose use carries real risks — cardiomyopathy, hearing loss, and vision loss have been reported, though they're rare. Your risk may be higher if you have a low-protein diet, are thiamine-deficient, or have hypothyroidism. This is another reason inorganic cobalt supplements aren't recommended.
Can I take this while pregnant or breastfeeding?
No. The safety data advises against cobalt supplements during pregnancy because of toxicity concerns and a lack of safety data. While breastfeeding, avoid cobalt supplements and rely on vitamin B12 for any cobalt your body needs.
Are there any side effects I should watch for?
In the short term, cobalt is generally well tolerated in small amounts. Over time or at higher doses, watch for hearing problems, vision changes, or signs of a weakening heart — though these are rare. If you have skin sensitivity, cobalt-containing products can trigger allergic reactions.
What's the difference between cobalt and vitamin B12?
Cobalt is an element; vitamin B12 is a compound that contains cobalt. Your body gets cobalt naturally when you consume B12 from food or supplements. Inorganic cobalt supplements like this one don't offer the same benefit as B12 and come with toxicity risks that B12 does not.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Somaplex 2 Cobalt is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Somaplex 2 Cobalt label
Go deeper

The Full Monographs Behind Somaplex 2 Cobalt’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cobalt

Cobalt is a trace element that the body only needs as part of vitamin B12 (cobalamin); there is no proven reason to take inorganic cobalt supplements, and doing so can be harmful. If you nee...

Read the full Cobalt monograph →
Sources

Sources & How We Checked

Somaplex 2 Cobalt's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cobalt 11 references
  1. Packer M. Cobalt cardiomyopathy: a critical reappraisal in light of a recent resurgence. Circ Heart Fail 2016;9(12). pii: e003604. PubMed
  2. Adams TN, Butt YM, Batra K, Glazer CS. Cobalt related interstitial lung disease. Respir Med 2017;129:91-7. PubMed
  3. Lim CA, Khan J, Chelva E, Khan R, Unsworth-Smith T. The effect of cobalt on the human eye. Doc Ophthalmol 2015;130(1):43-8. PubMed
  4. Guarneri F, Guarneri C, Cannavò SP. Nail-art and cobalt allergy. Contact Dermatitis 2010;62(5):320-1. PubMed
  5. Fowler JF Jr. Cobalt. Dermatitis 2016;27(1):3-8.
  6. Zajdel NJ, Smith WA, Taintor AR, Jacob SE, Olasz EB. Chemical tattoo treatment leading to systemic cobalt hypersensitivity. Skinmed 2017;15(3):221-2.
  7. Bregnbak D, Opstrup MS, Jellesen MS, Johansen JD, Thyssen JP. Allergic contact dermatitis caused by cobalt in leather - clinical cases. Contact Dermatitis 2017;76(6):366-8. PubMed
  8. Simonsen AB, Friis UF, Johansen JD, Zachariae C, Sloth JJ, Thyssen JP. Occupational allergic contact dermatitis caused by cobalt in machine oil. Contact Dermatitis 2019;80(1):59-61. PubMed
  9. Paustenbach DJ, Galbraith DA, Finley BL. Interpreting cobalt blood concentrations in hip implant patients. Clin Toxicol (Phila) 2014;52(2):98-112. PubMed
  10. Zywiel MG, Cherian JJ, Banerjee S, et al. Systemic cobalt toxicity from total hip arthroplasties: review of a rare condition Part 2. measurement, risk factors, and step-wise approach to treatment. Bone Joint J 2016;98-B(1):14-20. PubMed
  11. Catalani S, Rizzetti MC, Padovani A, Apostoli P. Neurotoxicity of cobalt. Hum Exp Toxicol 2012;31(5):421-37. PubMed

See these in context on the Cobalt monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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