No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Somaplex 1 Bismuth Ingredients & Drug Interactions

by Nestmann

Somaplex 1 Bismuth label
See full label image
Liquid Category: Non-nutrient/non-botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Somaplex 1 Bismuth against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Somaplex 1 Bismuth is a dietary supplement by Nestmann with 1 active ingredient. Its ingredients are commonly taken for upset stomach and indigestion, diarrhea, wound and skin protection (topical).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Somaplex 1 Bismuth by Nestmann

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bismuth nitrate. It's included in formulations historically used for digestive support, though the evidence for its effectiveness is limited.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Bismuth Nitrate product and its label doesn't state a use — see Bismuth Nitrate's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The data we hold shows insufficient reliable evidence to rate bismuth nitrate for Helicobacter pylori (a stomach bacterium). We don't have effectiveness information for other uses you may be considering.

The evidence, ingredient by ingredient Bismuth Nitrate

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bismuth nitrate is not a standard supplement and carries toxicity risks — the facts advise it should only be used under professional guidance. Short-term use may cause loss of appetite or headache.

Chronic use raises more serious concerns: it can stain your gums black, cause a "bismuth line" on the gums, lead to bad breath, or in rare cases trigger bismuth encephalopathy (a serious brain condition marked by confusion, restlessness, and seizures). Bismuth nitrate may also cause methemoglobinemia, a blood condition that can bring on shortness of breath, skin discoloration, dizziness, and in severe cases dysrhythmias or coma.

The safety data advises against use during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Bismuth Nitrate

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check. That said, because bismuth nitrate can affect your blood and nervous system, tell your pharmacist or doctor you're using it before starting any new medications.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This is a specialized ingredient that should only be taken under a doctor's or pharmacist's supervision — not a self-treat supplement. If you're considering it for stomach issues, talk with your healthcare provider first about whether it's right for you and how long you can safely use it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Somaplex 1 Bismuth, straight from the product label.

Brand Nestmann
Net contents 1 fl. Oz.; 29.5 mL
Market status On market
Date entered into DSLD Sep 25, 2013
DSLD ID 25461
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Children (All)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Somaplex 1 Bismuth by Nestmann, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
22.5 mL
Maximum serving Sizes:
45 mL
Servings per container
65
IngredientAmount% DV
Bismuth Nitrate0.044 mg--

Other ingredients: Water, ethyl alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Adults take 15 drops on the tongue or rub into inner elbow two times daily. Children receive 1/2 or less of the adult amount.

Precautions

Tamper Evident: Use this product only if tamper evident ring has not been broken away from base of cap.

General Statements

3093

IONIZED TRACE ELEMENTS

1

>>NESTMANN<<

Made in Germany Nestmann Pharma Zapfendorf/Bamberg

FDA Statement of Identity

SUPPLEMENT

Seals/Symbols

MPI

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Somaplex 1 Bismuth by Nestmann label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Somaplex 1 Bismuth label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Somaplex 1 Bismuth by Nestmann

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size22.5 mL Dosage formLiquid Servings per container65 Amounts shown are per serving.

Bismuth Nitrate

No known
interactions
0.044 mg per serving

Bismuth nitrate is a bismuth-based chemical compound that was historically used for stomach complaints and as a mild topical antiseptic, but it is not...

Bismuth Nitrate monograph & interactions

Other (inactive) ingredients: Water, Ethyl alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Somaplex 1 Bismuth by Nestmann Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Somaplex 1 Bismuth. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Somaplex 1 Bismuth, from the product label.

Nestmann

See all Nestmann products
Name
Marco Pharma Int'l
City
Roseburg
State
OR
ZipCode
97470
Pharmacist Counseling Corner

Somaplex 1 Bismuth by Nestmann: Common Questions

Does Somaplex 1 Bismuth by Nestmann interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Somaplex 1 Bismuth. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Somaplex 1 Bismuth contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is bismuth nitrate used for?
Historically it's been used to support digestive health, but the evidence for it is insufficient to rate. If you're thinking of taking it for a specific condition, talk with your doctor first.
Can I take this while pregnant or breastfeeding?
No. The safety data advises against use during pregnancy, and safety while breastfeeding is unknown — so avoid it in both cases. Talk with your doctor about safe alternatives.
What are the side effects?
Short-term use may cause loss of appetite or headache. Long-term use can stain your gums, cause bad breath, and rarely trigger a serious brain condition called bismuth encephalopathy. It may also cause methemoglobinemia, a blood disorder with symptoms like shortness of breath and dizziness — in severe cases, it can be life-threatening.
Is this safe to use on my own?
No — the facts say it should only be used under professional guidance because it can pose toxicity risks. Your doctor or pharmacist needs to supervise your use.
How long can I safely take this?
The data doesn't specify a safe duration, but chronic use carries serious risks including brain and blood damage. This is another reason to use it only under professional supervision.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Somaplex 1 Bismuth is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Somaplex 1 Bismuth label
Go deeper

The Full Monographs Behind Somaplex 1 Bismuth’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bismuth Nitrate

Bismuth nitrate is a bismuth-based chemical compound that was historically used for stomach complaints and as a mild topical antiseptic, but it is not a common modern dietary supplement and...

Read the full Bismuth Nitrate monograph →
Sources

Sources & How We Checked

Somaplex 1 Bismuth's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bismuth Nitrate 6 references
  1. - Jaeger A, Kopferschmitt J, Sauder Ph, Flesch F, Tournoud C. Diagnosis in clinical toxicology. In: Bolt HM, de Wolff FA, Henderson PT (eds) Medical Toxicology. Archives of Toxicology (Supplement). Berlin/Heidelberg, Germany: Springer-Verlag; 1992:29-39. PubMed
  2. Bismuth nitrate; MSDS No. B3396 [Online]; Mallenckrodt Baker: Phillipsburg, NJ, December 8, 1996. https://hazard.com/msds/mf/baker/baker/files/b3396.htm (accessed December 27, 2019).
  3. Saberi-Firoozi M, Massarrat S, Zare S, et al. Effect of triple therapy or amoxycillin plus omeprazole or amoxycillin plus tinidazole plus omeprazole on duodenal ulcer healing, eradication of Helicobacter pylori, and prevention of ulcer relapse over a 1-ye
  4. Von Bose MJ, Zaudig M. Encephalopathy resembling Creutzfeldt-Jakob disease following oral, prescribed doses of bismuth nitrate. Br J Psychiatry. 1991;158:278-80. PubMed
  5. Lewis RJ Sr. Hazardous Chemicals Desk Reference. 6th Edition. Hoboken, NJ: Wiley; 2008.
  6. Raafat BM, Samir WA, Khader MH. Met-Hemoglobin concentration reduction and methemoglobin reductase enhancement after applying of alpha-tocopherol and selenium combination as a radio protector against ionizing radiation exposure. Wulfenia J. 2012;19(10):37

See these in context on the Bismuth Nitrate monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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