Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Ionic Iodine from Potassium Iodide 225 mcg Ingredients & Drug Interactions

by Trace Minerals Research

Ionic Iodine from Potassium Iodide 225 mcg label
See full label image
Liquid Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ionic Iodine from Potassium Iodide 225 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ionic Iodine from Potassium Iodide 225 mcg is a dietary supplement by Trace Minerals Research with 2 active ingredients. Its ingredients are commonly taken for preventing iodine deficiency, supporting thyroid hormone production, general energy and metabolism support.Based on those ingredients, 7 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Iodine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Ionic Iodine from Potassium Iodide 225 mcg by Trace Minerals Research

Ask about any prescription or over-the-counter medication and we check it for interactions with Ionic Iodine from Potassium Iodide 225 mcg by Trace Minerals Research — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Ionic Iodine from Potassium Iodide 225 mcg by Trace Minerals Research

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid supplement provides 2 active ingredients: iodine at 225 mcg per serving and Ionic Trace Minerals. Iodine is an essential mineral your body needs for thyroid function and metabolism.

The remaining ingredients—purified water, potassium benzoate, potassium sorbate, and citric acid—are inactive components that preserve and stabilize the product.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: iodine supplementation for thyroid function.
  • We looked for evidence on: Iodine deficiency, Infant development, Radiation exposure, Hypothyroidism, Goiter, Thyroid hormone synthesis.
  • The strongest evidence on file: Iodine is rated "Likely Effective" for Radiation exposure (Natural Medicines).
  • Also on file: Iodine is rated "Likely Effective" for Iodine deficiency.
  • Also on file: Iodine is rated "Insufficient Reliable Evidence To Rate" for Infant development.

Iodine is likely effective for protecting the thyroid after radiation exposure and for correcting iodine deficiency. The evidence is possibly effective for oral mucositis (mouth sores) and periodontitis (gum disease), though the data is less established for those uses.

The evidence, ingredient by ingredient Iodine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Iodine is well tolerated in normal dietary amounts, but high doses can cause thyroid problems—hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid)—and other side effects including nausea, metallic taste, headache, diarrhea, and goiter (enlarged thyroid). Rarely, some people experience allergic reactions such as hives, fever, or swelling.

During pregnancy, adequate iodine matters for your baby's development, but use only the amount your doctor advises and avoid high-dose products. Some iodine passes into breast milk, so follow your doctor's guidance if you're nursing.

If you have a personal or family history of thyroid disease, talk with your doctor or pharmacist before starting this supplement.

Side effects, ingredient by ingredient Iodine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Iodine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 7 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take lithium (a mood stabilizer), any antithyroid drugs such as propylthiouracil or methimazole, or amiodarone (a heart medication). These Moderate interactions can affect thyroid function and may require monitoring of your thyroid blood tests.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This iodine supplement is appropriate for people with documented iodine deficiency or those needing radiation protection under medical supervision. If you take lithium, antithyroid medications, or amiodarone, you need to check with your doctor or pharmacist before using it—the interactions could affect your thyroid function.

Even without those medications, discuss it with your healthcare provider first, especially if you have thyroid disease or are pregnant or nursing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ionic Iodine from Potassium Iodide 225 mcg, straight from the product label.

Brand Trace Minerals Research
Barcode (UPC) 878941003073
Net contents 2 fl. Oz.; 59 mL
Market status On market
Date entered into DSLD Feb 23, 2016
DSLD ID 57057
Product type Mineral
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ionic Iodine from Potassium Iodide 225 mcg by Trace Minerals Research, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.2 mL
Maximum serving Sizes:
0.2 mL
Servings per container
320
UPC/BARCODE
878941003073
IngredientAmount% DV
Iodine225 mcg--
Ionic Trace Minerals100 mg--

Other ingredients: purified Water, Potassium Benzoate, Potassium Sorbate, Citric Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

AMERICA'S #1 TRACE MINERAL BRAND

Iodine is an important mineral that is used in the body in several different ways.* It may help support the following: healthy thyroid function, ATP production, hormone production, central nervous system function, immune function, and skin health.*

FEEL THE DIFFERENCE GUARANTEED OR YOUR MONEY BACK

Brand IP Statement(s)

liquimins

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

CONTAINS NO GENETICALLY MODIFIED INGREDIENTS NON-GMO

cGMP

Certified Vegan AVA American Vegetarian Association

Formulation

NON-GMO

CERTIFIED VEGAN.

Allergen Info: contains no known allergens.

GLUTEN FREE.

Storage

Do not refrigerate.

Suggested/Recommended/Usage/Directions

Suggested Use: Shake well. Using the metered dropper, take 3 drops daily with juice or food to mask the concentrated mineral flavor.

The metered dropper allows for personalized dosing, if needed.

Precautions

Keep out of reach of children.

Formula

Ionic Iodine is a rich, concentrated liquid dietary supplement that provides 225 mcg of iodine from potassium iodide per serving, plus over 72 naturally-occurring ionic trace minerals.

General

r-M12Y15

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ionic Iodine from Potassium Iodide 225 mcg by Trace Minerals Research label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ionic Iodine from Potassium Iodide 225 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ionic Iodine from Potassium Iodide 225 mcg by Trace Minerals Research

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.2 mL Dosage formLiquid Servings per container320 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Iodine

Interacts with
7 drugs
225 mcg per serving Form: Potassium Iodide

Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements...

Iodine monograph & interactions

Ionic Trace Minerals

100 mg per serving

Other (inactive) ingredients: Purified Water, Potassium Benzoate, Potassium Sorbate, Citric Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ionic Iodine from Potassium Iodide 225 mcg by Trace Minerals Research Drug Interactions

Want to check YOUR meds against Ionic Iodine from Potassium Iodide 225 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
7Drugs
7 Moderate

Ingredients driving the most interactions

Iodine 7

Individual Drug Interactions

The ingredients in Ionic Iodine from Potassium Iodide 225 mcg interact with 7 drugs. Click any drug to see the details.

1 of the 2 ingredients in Ionic Iodine from Potassium Iodide 225 mcg interact with drugs. Each result below shows which ingredient is responsible. Iodine

Each ingredient & the kinds of drugs it affects

For each ingredient in Ionic Iodine from Potassium Iodide 225 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Iodine3 drug types · 7 drugs

Amiodarone (Cordarone)

Combining iodine with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with iodine might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.

Likelihood Probable Evidence D
Antithyroid Drugs

Iodine might alter the effects of antithyroid drugs.
Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking iodine while using antithyroid drugs could alter the effects of the antithyroid drugs.

Likelihood Probable Evidence D
Lithium

Combining iodine with lithium might have additive hypothyroid effects.
Lithium can inhibit thyroid function. Several case reports suggest that concomitant use of lithium and potassium iodide can reduce thyroid function in otherwise healthy adults. Monitor thyroid function.

Likelihood Probable Evidence D
Iodine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ionic Iodine from Potassium Iodide 225 mcg, from the product label.

Trace Minerals Research

See all Trace Minerals Research products
Name
Trace Minerals Research
Street Address
P.O. Box 429
City
Roy
State
Utah
ZipCode
84067
Phone Number
801.731.6051
Web Address
www.traceminerals.com
Pharmacist Counseling Corner

Ionic Iodine from Potassium Iodide 225 mcg by Trace Minerals Research: Common Questions

Does Ionic Iodine from Potassium Iodide 225 mcg by Trace Minerals Research interact with any medications?
Yes. Based on its ingredients, Ionic Iodine from Potassium Iodide 225 mcg has a known interaction with 7 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ionic Iodine from Potassium Iodide 225 mcg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
How much iodine do I actually need?
Most healthy adults need 150 mcg of iodine daily. This product provides 225 mcg per serving, which is above the daily requirement. Use it only under your doctor's guidance, especially since the safety notes emphasize following medical advice on dose.
Can I take this if I'm pregnant or breastfeeding?
The data shows iodine is likely safe in pregnancy when used appropriately and possibly unsafe when overused. Because adequate iodine is important for your baby but excess can be harmful, take only the amount your doctor specifically advises. Talk with your doctor or pharmacist before starting any supplement while pregnant or nursing.
What are the most common side effects?
The most common side effects from oral iodine are abdominal upset, diarrhea, nausea, headache, and metallic taste. Rarely, people develop allergic reactions like hives or swelling. If you notice any new symptoms, talk to your pharmacist or doctor.
What's the difference between an iodine allergy and iodine sensitivity?
Many people labeled "iodine allergic" are actually reacting to seafood proteins or radiocontrast dye, not iodine itself. However, some people can be genuinely hypersensitive to iodine when taken by mouth, with symptoms like hives, swelling, or fever. If you've had a bad reaction to iodine-containing products before, tell your doctor or pharmacist.
Why does this product have lithium interactions if I don't take lithium?
The interactions listed apply only to you if you take those specific medications. If you don't take lithium, antithyroid drugs, or amiodarone, those interactions won't affect you. Still, check your full medication list using the tool on this page to be sure.
Is this supplement safe for long-term use?
Iodine is well tolerated at normal dietary doses, but high doses taken over a long time can cause thyroid problems and acneform skin lesions. This product is above the standard daily requirement, so discuss with your doctor whether it's right for your situation and how long to take it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ionic Iodine from Potassium Iodide 225 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ionic Iodine from Potassium Iodide 225 mcg label
Go deeper

The Full Monographs Behind Ionic Iodine from Potassium Iodide 225 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Iodine

Interacts with 7 drugs

Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements help when you are truly deficient, but...

Read the full Iodine monograph →
Sources

Sources & How We Checked

Ionic Iodine from Potassium Iodide 225 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Iodine 26 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
  3. Ghent WR, Eskin BA, Low DA, Hill LP. Iodine replacement in fibrocystic disease of the breast. Can J Surg 1993;36:453-60.
  4. Potassium iodide for nuclear exposure. Pharmacist's Letter/Prescriber's Letter 2001;17(12):171214.
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cabezas C, Bustamante B, Holgado W, Begue RE. Treatment of cutaneous sporotrichosis with one daily dose of potassium iodide. Pediatr Infect Dis J 1996;15:352-4. PubMed
  7. Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
  8. Yarrington CD, Pearce EN. Dietary iodine in pregnancy and postpartum. Clin Obstet Gynecol 2011;54:459-70. PubMed
  9. Goel, S., Mandhani, A., Srivastava, A., Kapoor, R., Gogoi, S., Kumar, A., and Bhandari, M. Is povidone iodine an alternative to silver nitrate for renal pelvic instillation sclerotherapy in chyluria? BJU.Int 2004;94(7):1082-1085. PubMed
  10. Teng, W., Shan, Z., Teng, X., Guan, H., Li, Y., Teng, D., Jin, Y., Yu, X., Fan, C., Chong, W., Yang, F., Dai, H., Yu, Y., Li, J., Chen, Y., Zhao, D., Shi, X., Hu, F., Mao, J., Gu, X., Yang, R., Tong, Y., Wang, W., Gao, T., and Li, C. Effect of iodine int
  11. Crawford, B. A., Cowell, C. T., Emder, P. J., Learoyd, D. L., Chua, E. L., Sinn, J., and Jack, M. M. Iodine toxicity from soy milk and seaweed ingestion is associated with serious thyroid dysfunction. Med J Aust. 10-4-2010;193(7):413-415. PubMed
  12. Ohkuma, M. Molluscum contagiosum treated with iodine solution and salicylic acid plaster. Int J Dermatol. 1990;29(6):443-445. PubMed
  13. Connelly KJ, Boston BA, Pearce EN, Sesser D, Snyder D, Braverman LE, Pino S, LaFranchi SH. Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion. J Pediatr. 2012 Oct;161(4):760-2. PubMed
  14. Kasahara T, Narumi S, Okasora K, Takaya R, Tamai H, Hasegawa T. Delayed onset congenital hypothyroidism in a patient with DUOX2 mutations and maternal iodine excess. Am J Med Genet A. 2013 Jan;161A(1):214-7.
  15. Murcia M, Rebagliato M, Iñiguez C, Lopez-Espinosa MJ, Estarlich M, Plaza B, Barona-Vilar C, Espada M, Vioque J, Ballester F. Effect of iodine supplementation during pregnancy on infant neurodevelopment at 1 year of age. Am J Epidemiol. 2011 Apr 1;173(7):8 PubMed
  16. Sang Z, Wang PP, Yao Z, Shen J, Halfyard B, Tan L, Zhao N, Wu Y, Gao S, Tan J, Liu J, Chen Z, Zhang W. Exploration of the safe upper level of iodine intake in euthyroid Chinese adults: a randomized double-blind trial. Am J Clin Nutr. 2012 Feb;95(2):367-73 PubMed
  17. Speeckaert MM, Speeckaert R, Wierckx K, Delanghe JR, Kaufman JM. Value and pitfalls in iodine fortification and supplementation in the 21st century. Br J Nutr. 2011 Oct;106(7):964-73. PubMed
  18. Yun SE, Kang Y, Bae EJ, Hwang K, Jang HN, Cho HS, Chang SH, Park DJ. Iodine-induced thyrotoxic hypokalemic paralysis after ingestion of Salicornia herbace. Ren Fail. 2014 Apr;36(3):461-3.
  19. Iodine Hypersensitivity. Pharmacist's Letter/Prescriber's Letter 2011; 27(5):270504.
  20. Hammel JA, Selby JC. Pustular eruption in a patient with cancer treated with complementary and alternative medicine. JAMA Dermatology 2017 October; E1. doi: 10.1001/jamadermatol.2017.3749. [Epub ahead of print] PubMed
  21. Gil GS, Smith BW, Guerra JR, Williams WT. Acute Delirium in a Hypothyroid Patient Precipitated by Iodine Supplements Use. Am J Ther. 2018;25(6):e717-e718. PubMed
  22. Hamby T, Kunnel N, Dallas JS, Wilson DP. Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism. J Pediatr Endocrinol Metab. 2018;31(9):1061-1064. PubMed
  23. Censi S, Watutantrige-Fernando S, Groccia G, et al. The Effects of Iodine Supplementation in Pregnancy on Iodine Status, Thyroglobulin Levels and Thyroid Function Parameters: Results from a Randomized Controlled Clinical Trial in a Mild-to-Moderate Iodine
  24. Rovner MS, Wolf BJ, Rubin M, et al. Instillation of 5% Povidone-Iodine Ophthalmic Drops Decreases the Respiratory Rate in Children Undergoing Strabismus Surgery: A Randomized Controlled Trial. J Pediatr Ophthalmol Strabismus. 2019;56(6):378-382. PubMed
  25. Guenezan J, Garcia M, Strasters D, et al. Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2021;147(4):400-401. PubMed
  26. Li F, Wan S, Zhang L, et al. A Meta-Analysis of the Effect of Iodine Excess on the Intellectual Development of Children in Areas with High Iodine Levels in their Drinking Water. Biol Trace Elem Res 2022;200(4):1580-1590. PubMed

See these in context on the Iodine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team