No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Kre-Alkalyn pH-Correct Creatine Ingredients & Drug Interactions

by All American EFX

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Kre-Alkalyn pH-Correct Creatine is a dietary supplement by All American EFX with 1 active ingredient. Its ingredients are commonly taken for improving high-intensity exercise performance, building muscle strength and size, sports and athletic training.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Kre-Alkalyn pH-Correct Creatine by All American EFX

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Kre-Alkalyn pH-Correct Creatine, a form of creatine designed to be less acidic than standard creatine monohydrate. Creatine is a compound your muscles use to produce energy during intense exercise and strength work.

The capsules also contain two inactive ingredients — maltodextrin and magnesium stearate — which are fillers and binders that help form and stabilize the supplement.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle strength and athletic performance.
  • We looked for evidence on: Athletic performance, Muscle strength, Physical performance, Muscle breakdown, Postoperative recovery, Sarcopenia.
  • The strongest evidence on file: Creatine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Creatine is rated "Possibly Effective" for Muscle strength, Sarcopenia.
  • Also on file: Creatine is rated "Insufficient Reliable Evidence To Rate" for Muscle breakdown, Physical performance, Postoperative recovery.

The evidence supports creatine for a few specific uses. It's possibly effective for muscle strength, athletic performance, sarcopenia (age-related muscle loss), and cerebral creatine deficiency syndromes — rare genetic disorders affecting the brain's ability to use creatine.

For Huntington disease and osteopenia (low bone density), the research suggests it's possibly ineffective. The data we hold doesn't establish effectiveness for any other uses you might have in mind.

The evidence, ingredient by ingredient Creatine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Creatine is generally well tolerated in healthy adults, but if you have kidney problems, you should be cautious and talk with your doctor before starting. The most common side effects from oral creatine are dehydration, diarrhea, stomach upset, muscle cramps, and water retention — usually mild and temporary.

Rarely, case reports have raised concerns about kidney inflammation and muscle breakdown, though these are uncommon. Some people — especially those who are immobilized — may experience water retention or swelling.

During pregnancy, the safety data advises against use. For nursing mothers, there isn't enough safety information, so it's best to avoid it as well.

If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Creatine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient we checked. That doesn't mean interactions can't occur, only that we have no monograph data showing them.

If you take any medications, ask your doctor or pharmacist before starting this product.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Kre-Alkalyn is worth considering if you're focused on building muscle strength or improving athletic performance and want creatine's evidence-backed support. If you have kidney disease or are pregnant or breastfeeding, skip this one.

Before you start, talk it over with your doctor or pharmacist — especially if you have any kidney concerns or take prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kre-Alkalyn pH-Correct Creatine, straight from the product label.

Brand All American EFX
Barcode (UPC) 737190001196
Net contents 160 Count Bottle
Market status On market
Date entered into DSLD Oct 26, 2011
DSLD ID 625
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kre-Alkalyn pH-Correct Creatine by All American EFX, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
80
UPC/BARCODE
737190001196
IngredientAmount% DV
Kre-Alkalyn pH-Correct Creatine1.5 Gram(s)50%

Other ingredients: Maltodextrin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

(C)2008 All American EFX(R) All Rights Reserved

Get Noticed(TM)

Kre-Alkalyn(R) EFX is the only creatine monohydrate product in the world with a pH above 12 because its molecules are synthesized with "buffering" agents using a patented manufacturing process. As a results, it passes intact to the bloodstream and reaches muscle cells at full strength.

Kre-Alkalyn(R) EFX's patents also cover all pH levels from 7-14. Therefore, the pH of all other creatine products must be pH 6.9 or less - meaning they will all lose potency in liquids.

pH-Controlled pHCD(TM) Delivery

THE FLEX WHEELER NATURAL FREAK(TM) SIGNATURE EDITION

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Storage

Keep tightly closed in a cool, dry place away from children.

General Statements

Brian Andrews (President): We are committed to supporting the needs of athletes who passionately want to achieve greatness without sacrificing their health, freedom, or integrity to do it. That's the way of the Natural Freak(TM). And the product you are now holding is one of the best tools available today to help you make your goals a reality!

EFX

EU Plant #1000135313 * In God We Trust * AA8263-160

Flex Wheeler Bodybuilding Legend

Flex Wheeler (Bodybuilding Legend): More than any other question, I'm asked what supplements I personally use and recommend. My answer is the same every time: Kre-Alkalyn(R) EFX creatine - the multi-patented, award-wining creatine by All American EFX. In fact, I believe in the technology behind this product so much, I've put my name on it. You don't have to load or cycle it. And there's no bloating or side-effects. You just get incredible pumps and amazing strength during every workout. All American EFX and I are on a mission to provide you with the very finest drug-free options available on the market today. Now you have a choice...won't you join us?

For the serious sport and physique athlete who desires a drug-free alternative

Here's What Makes Kre-Alkalyn(R) EFX Creatine A Category Of One: Kre-Alkalyn(R) EFX is manufactured within the pH-Correct Zone of pH 12 - 14 Kre-Alkalyn(R) EFX's patent strategically protects the "Creatine-Potency Zone" of pH 7 - pH 14 All other creatine based products exist inside the degradation zone of pH 0 - 6.9. Without critical pH protection (pH above 7.0) creatine loses potency

INCREASE YOUR: *Lean muscle mass* *Training Intensity* *Real-World Strength*

Jeff Golini (Chief Formulator): All American EFX and I are dedicated to advancing the science of drug-free phsique and performance enhancement technology. In short, multi-patented Kre-Alkalyn(R) EFX represents one of the greatest examples of our work together.

NATURAL FREAK. Pure. Potent. Drug-Free: For a "natural" there is no greater compliment than to be officially recognized as a "Natural Freak(TM)". Are you one? Log on to our site to see if you qualify.

No Loading * No Bloating * No Cycling

Special 160 Count Bottle

THE ALL AMERICAN EFX PROMISE TO YOU - OUR VALUED CUSTOMER

The world's only patented, 100% stable creatine

U.S Patent #6,399,661

Uncompromising Standards:

Why a protective pH of 12-14 is so important:

Seals/Symbols

BRD Drug-Free Seal: We know your reputation and career are on the line and that's why we go the extra mile. Every batch is independently tested for drugs and other banned substances. CERTIFIED DRUG-FREE

Buchi Seal of Purity: We take what you put into your body very seriously. When you see this logo on our products, you'll know without a doubt it's everything we claim.

Suggested/Recommended/Usage/Directions

SUGGESTED USE: As a dietary supplement take 2 capsules daily. 1 pre-workout and 1 post-workout.

See for yourself

Kre-Alkalyn pH-Correct Creatine by All American EFX label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Kre-Alkalyn pH-Correct Creatine by All American EFX

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container80 Amounts shown are per serving.

Kre-Alkalyn pH-Correct Creatine

No known
interactions
1.5 Gram(s) per serving

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...

Kre-Alkalyn pH-Correct Creatine monograph & interactions

Other (inactive) ingredients: Maltodextrin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kre-Alkalyn pH-Correct Creatine by All American EFX Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Kre-Alkalyn pH-Correct Creatine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Kre-Alkalyn pH-Correct Creatine, from the product label.

All American EFX

See all All American EFX products
Name
All American EFX
Pharmacist Counseling Corner

Kre-Alkalyn pH-Correct Creatine by All American EFX: Common Questions

Does Kre-Alkalyn pH-Correct Creatine by All American EFX interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Kre-Alkalyn pH-Correct Creatine. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Kre-Alkalyn pH-Correct Creatine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Kre-Alkalyn, and how is it different from regular creatine?
Kre-Alkalyn is a pH-corrected form of creatine — meaning it's been buffered to be less acidic than standard creatine monohydrate. The idea is that a less acidic form may be easier on your stomach and more stable in your body, though both forms work similarly for muscle strength and athletic performance.
Will this help me build muscle?
Creatine is possibly effective for muscle strength and athletic performance. It works by helping your muscles produce energy during intense exercise, so it's most useful if you're doing resistance training or high-intensity work. It doesn't build muscle on its own — you still need the training and the right nutrition.
What are the most common side effects?
The most common ones are dehydration, diarrhea, stomach upset, muscle cramps, and water retention. These tend to be mild and temporary. Serious side effects are rare, but if you have kidney problems, talk with your doctor first.
Is it safe if I'm pregnant or breastfeeding?
No — the safety data advises against it during pregnancy. For breastfeeding, there isn't enough safety information, so you should avoid it as well. Talk with your doctor or pharmacist if you're in either situation and thinking about creatine.
Can I take this if I have kidney disease?
You should be cautious and talk with your doctor first. While creatine is generally well tolerated, those with kidney issues need to be careful because creatine is processed through the kidneys. Your doctor can advise whether it's safe for your situation.
How much water should I drink while taking creatine?
The product facts we hold don't give a specific amount, but staying well hydrated is important since dehydration is a common side effect. Ask your doctor or pharmacist for personalized advice on how much water is right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Kre-Alkalyn pH-Correct Creatine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kre-Alkalyn pH-Correct Creatine label
Go deeper

The Full Monographs Behind Kre-Alkalyn pH-Correct Creatine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Kre-Alkalyn pH-Correct Creatine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 86 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Creatine 86 references
  1. Koshy KM, Griswold E, Schneeberger EE. Interstitial nephritis in a patient taking creatine. N Engl J Med 1999;340:814-5. PubMed
  2. Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
  3. Greenhaff P. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;352:233-4. PubMed
  4. Vandenberghe K, Goris M, Van Hecke P, et al. Long-term creatine intake is beneficial to muscle performance during resistance training (abstract). J Appl Physiol 1997;83:2055-63. PubMed
  5. Hultman E, Soderlund K, Timmons JA, et al. Muscle creatine loading in men. J Appl Physiol 1996;81:232-7. PubMed
  6. Pritchard NR, Kalra PA. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;351:1252-3. PubMed
  7. Poortmans JR, Auquier H, Renaut V, et al. Effect of short-term creatine supplementation on renal responses in men (abstract). Eur J Appl Physiol Occup Physiol 1997;76:566-7. PubMed
  8. Poortmans JR, Francaux M. Long-term oral creatine supplementation does not impair renal function in healthy athletes. Med Sci Sports Exerc 1999;31:1108-10. PubMed
  9. Mihic S, MacDonald JR, McKenzie S, Tarnopolsky MA. Acute creatine loading increases fat-free mass, but does not affect blood pressure, plasma creatinine, or CK activity in men and women. Med Sci Sports Exerc 2000;32:291-6. PubMed
  10. Rawson ES, Wehnert ML, Clarkson PM. Effects of 30 days of creatine ingestion in older men. Eur J Appl Physiol Occup Physiol 1999;80:139-44. PubMed
  11. Earnest CP, Almada AL, Mitchell TL. High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women. Clin Sci (Colch) 1996;91:113-8. PubMed
  12. Juhn MS. Oral creatine supplementation. Separating fact from hype. Phys Sportsmed 1999;27:47-50,53-54,56,61,89. PubMed
  13. Juhn MS, O'Kane JW, Vinci DM. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am Diet Assoc 1999;99:593-5.
  14. Green AL, Hultman E, Macdonald IA, et al. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am J Physiol 1996;271:E821-6. PubMed
  15. Balsom PD, Soderlund K, Sjodin B, Ekblom B. Skeletal muscle metabolism during short duration high-intensity exercise: influence of creatine supplementation. Acta Physiol Scand 1995;154:303-10. PubMed
  16. Snow RJ, McKenna MJ, Selig SE, et al. Effect of creatine supplementation on sprint exercise performance and muscle metabolism. (abstract) J Appl Physiol 1998;84:1667-73. PubMed
  17. McNaughton LR, Dalton B, Tarr J. The effects of creatine supplementation on high-intensity exercise performance in elite performers. (abstract) Eur J Appl Physiol Occup Physiol 1998;78:236-40. PubMed
  18. Groeneveld GJ, Veldink JH, van der Tweel I, et al. A randomized sequential trial of creatine in amyotrophic lateral sclerosis. Ann Neurol 2003;53:437-45. . PubMed
  19. Robinson SJ. Acute quadriceps compartment syndrome and rhabdomyolysis in a weight lifter using high-dose creatine supplementation. J Am Board Fam Pract 2000;13:134-7. PubMed
  20. Kammer RT. Lone atrial fibrillation associated with creatine monohydrate supplementation. Pharmacotherapy 2005;25:762-4. PubMed
  21. Gualano B, Ugrinowitsch C, Novaes RB, et al. Effects of creatine supplementation on renal function: a randomized, double-blind, placebo-controlled clinical trial. Eur J Appl Physiol 2008;103:33-40. PubMed
  22. Pfeffer, G., Majamaa, K., Turnbull, D. M., Thorburn, D., and Chinnery, P. F. Treatment for mitochondrial disorders. Cochrane Database.Syst.Rev. 2012;4:CD004426. PubMed
  23. Boos, C. J., White, S. H., Bland, S. A., and McAllister, P. D. Dietary supplements and military operations: caution is advised. J R.Army Med Corps 2010;156(1):41-43. PubMed
  24. Kreider, R. B. Dietary supplements and the promotion of muscle growth with resistance exercise. Sports Med 1999;27(2):97-110. PubMed
  25. Juhn, M. S., O'Kane, J. W., and Vinci, D. M. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am.Diet.Assoc 1999;99(5):593-595.
  26. Volek, J. S., Duncan, N. D., Mazzetti, S. A., Putukian, M., Gomez, A. L., and Kraemer, W. J. No effect of heavy resistance training and creatine supplementation on blood lipids. Int J Sport Nutr.Exerc.Metab 2000;10(2):144-156. PubMed
  27. Robinson, T. M., Sewell, D. A., Casey, A., Steenge, G., and Greenhaff, P. L. Dietary creatine supplementation does not affect some haematological indices, or indices of muscle damage and hepatic and renal function. Br.J Sports Med 2000;34(4):284-288. PubMed
  28. Tarnopolsky, M. A. Potential benefits of creatine monohydrate supplementation in the elderly. Curr.Opin.Clin Nutr.Metab Care 2000;3(6):497-502. PubMed
  29. Tarnopolsky, M. A. and MacLennan, D. P. Creatine monohydrate supplementation enhances high-intensity exercise performance in males and females. Int J Sport Nutr.Exerc.Metab 2000;10(4):452-463. PubMed
  30. Arciero, P. J., Hannibal, N. S., III, Nindl, B. C., Gentile, C. L., Hamed, J., and Vukovich, M. D. Comparison of creatine ingestion and resistance training on energy expenditure and limb blood flow. Metabolism 2001;50(12):1429-1434. PubMed
  31. Chrusch, M. J., Chilibeck, P. D., Chad, K. E., Davison, K. S., and Burke, D. G. Creatine supplementation combined with resistance training in older men. Med Sci.Sports Exerc. 2001;33(12):2111-2117. PubMed
  32. Cox, G., Mujika, I., Tumilty, D., and Burke, L. Acute creatine supplementation and performance during a field test simulating match play in elite female soccer players. Int J Sport Nutr.Exerc.Metab 2002;12(1):33-46. PubMed
  33. Kilduff, L. P., Vidakovic, P., Cooney, G., Twycross-Lewis, R., Amuna, P., Parker, M., Paul, L., and Pitsiladis, Y. P. Effects of creatine on isometric bench-press performance in resistance-trained humans. Med Sci.Sports Exerc. 2002;34(7):1176-1183. PubMed
  34. Brose, A., Parise, G., and Tarnopolsky, M. A. Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults. J Gerontol A Biol.Sci.Med Sci. 2003;58(1):11-19. PubMed
  35. Volek, J. S., Ratamess, N. A., Rubin, M. R., Gomez, A. L., French, D. N., McGuigan, M. M., Scheett, T. P., Sharman, M. J., Hakkinen, K., and Kraemer, W. J. The effects of creatine supplementation on muscular performance and body composition responses to
  36. Tyler, T. F., Nicholas, S. J., Hershman, E. B., Glace, B. W., Mullaney, M. J., and McHugh, M. P. The effect of creatine supplementation on strength recovery after anterior cruciate ligament (ACL) reconstruction: a randomized, placebo-controlled, double-b DOI
  37. Groeneveld, G. J., Beijer, C., Veldink, J. H., Kalmijn, S., Wokke, J. H., and van den Berg, L. H. Few adverse effects of long-term creatine supplementation in a placebo-controlled trial. Int J Sports Med 2005;26(4):307-313. PubMed
  38. Astorino, T. A., Marrocco, A. C., Gross, S. M., Johnson, D. L., Brazil, C. M., Icenhower, M. E., and Kneessi, R. J. Is running performance enhanced with creatine serum ingestion? J Strength.Cond.Res 2005;19(4):730-734. PubMed
  39. Cramer, J. T., Stout, J. R., Culbertson, J. Y., and Egan, A. D. Effects of creatine supplementation and three days of resistance training on muscle strength, power output, and neuromuscular function. J Strength.Cond.Res 2007;21(3):668-677. PubMed
  40. Young, P., De, Jonghe P., Stogbauer, F., and Butterfass-Bahloul, T. Treatment for Charcot-Marie-Tooth disease. Cochrane.Database.Syst.Rev. 2008;(1):CD006052. PubMed
  41. Ostojic, S. M. and Ahmetovic, Z. Gastrointestinal distress after creatine supplementation in athletes: are side effects dose dependent? Res.Sports Med. 2008;16(1):15-22. PubMed
  42. Whitt, K. N., Ward, S. C., Deniz, K., Liu, L., Odin, J. A., and Qin, L. Cholestatic liver injury associated with whey protein and creatine supplements. Semin.Liver Dis. 2008;28(2):226-231. PubMed
  43. Koenig CA, Benardot D Cody M Thompson WR. Comparison of creatine monohydrate and carbohydrate supplementation on repeated jump height performance. J Strength Cond Res. 2008;22(4):1081-1086. PubMed
  44. Gordon, P. H., Cheung, Y. K., Levin, B., Andrews, H., Doorish, C., Macarthur, R. B., Montes, J., Bednarz, K., Florence, J., Rowin, J., Boylan, K., Mozaffar, T., Tandan, R., Mitsumoto, H., Kelvin, E. A., Chapin, J., Bedlack, R., Rivner, M., McCluskey, L.
  45. Bender, A., Samtleben, W., Elstner, M., and Klopstock, T. Long-term creatine supplementation is safe in aged patients with Parkinson disease. Nutr.Res. 2008;28(3):172-178. PubMed
  46. Parness, J. You're "hot" from pumping iron? Anesth.Analg. 2009;108(3):711-713. PubMed
  47. Gualano, B., Ferreira, D. C., Sapienza, M. T., Seguro, A. C., and Lancha, A. H., Jr. Effect of short-term high-dose creatine supplementation on measured GFR in a young man with a single kidney. Am.J.Kidney Dis. 2010;55(3):e7-e9. PubMed
  48. Saidi, H. and Mani, M. Severe metabolic acidosis secondary to coadministration of creatine and metformin, a case report. Am.J.Emerg.Med. 2010;28(3):388-6. PubMed
  49. Gualano, B., de, Salles Painelli, V, Roschel, H., Lugaresi, R., Dorea, E., Artioli, G. G., Lima, F. R., da Silva, M. E., Cunha, M. R., Seguro, A. C., Shimizu, M. H., Otaduy, M. C., Sapienza, M. T., da Costa, Leite C., Bonfa, E., and Lancha Junior, A. H.
  50. Neves, M., Jr., Gualano, B., Roschel, H., Lima, F. R., Lucia, de Sa-Pinto, Seguro, A. C., Shimizu, M. H., Sapienza, M. T., Fuller, R., Lancha, A. H., Jr., and Bonfa, E. Effect of creatine supplementation on measured glomerular filtration rate in postmeno
  51. Gufford, B. T., Sriraghavan, K., Miller, N. J., Miller, D. W., Gu, X., Vennerstrom, J. L., and Robinson, D. H. Physicochemical characterization of creatine N-methylguanidinium salts. J.Diet.Suppl 2010;7(3):240-252.
  52. Lugaresi, R., Leme, M., de, Salles Painelli, V, Murai, I. H., Roschel, H., Sapienza, M. T., Lancha Junior, A. H., and Gualano, B. Does long-term creatine supplementation impair kidney function in resistance-trained individuals consuming a high-protein di
  53. Poortmans, J. R. and Francaux, M. Renal dysfunction accompanying oral creatine supplements. Lancet 7-18-1998;352(9123):234. PubMed
  54. Maganaris, C. N. and Maughan, R. J. Creatine supplementation enhances maximum voluntary isometric force and endurance capacity in resistance trained men. Acta Physiol Scand. 1998;163(3):279-287. PubMed
  55. Vandebuerie, F., Vanden Eynde, B., Vandenberghe, K., and Hespel, P. Effect of creatine loading on endurance capacity and sprint power in cyclists. Int J Sports Med 1998;19(7):490-495. PubMed
  56. Juhn, M. S. and Tarnopolsky, M. Oral creatine supplementation and athletic performance: a critical review. Clin J Sport Med 1998;8(4):286-297. PubMed
  57. Vandenberghe K, Van Hecke P, Van Leemputte M, and et al. Inhibition of muscle phosphocreatine resynthesis by caffeine after creatine loading. Med Sci Sports Exerc 1997;29(5 Supplement):249.
  58. Ziegenfuss T, Lowery LM, and Lemon PW. Acute fluid volume changes in men during three days of creatine supplementation. J Exerc Physiol Online 1998;1(3): .
  59. Kuehl K, Goldberg L, and Elliot D. Renal insufficiency after creatine supplementation in a college football athlete. Med Sci Sports Exerc 1998;30(5 Suppl ):S235. DOI
  60. Balsom PD, Ekblom B, Soderlund K, and et al. Creatine supplementation and dynamic high-intensity intermittent excercise. Scand J Med Sci Sports 1993;3:143-149.
  61. Kirksey KB, Warren BJ, Stone MH, and et al. The effects of six weeks of creatine monohydrate supplementation in male and female track athletes. Med Sci Sports Exerc 1997;29(5 Suppl):S145.
  62. Kreider R, Ransom J, Rasmussen C, and et al. Creatine supplementation during pre-season football does not affect markers of renal function. 83rd Annual Experimental Biology Meeting 1999;
  63. Rasmussen C, Kreider R, Ransom J, and et al. Creatine supplementation during pre-season football training does not affect fluid or electrolyte status. 46th Annual American College of Sports Medicine Annual Meeting 1999; DOI
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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