L-Ergothioneine Ingredients & Drug Interactions
by Absonutrix
What is this page for?
First and foremost: checking L-Ergothioneine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Ergothioneine is a dietary supplement by Absonutrix with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, healthy aging and longevity, cellular protection.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of L-Ergothioneine by Absonutrix
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This liquid contains 2 active ingredients. L-Ergothioneine is an amino acid compound with antioxidant properties.
Oyster Mushroom Extract adds a mushroom-derived ingredient, though we don't have detailed information on its specific role in this formula. The product also contains inactive ingredients — water, ethanol, potassium sorbate, stevia, and peppermint oil — that serve as preservatives, sweeteners, and flavoring.
Does it work?
Couldn't assess
The evidence for L-Ergothioneine is limited. For coronary heart disease and joint pain, we don't yet have enough reliable evidence to rate how well it works.
If you're considering this supplement for either of those conditions, talk with your doctor or pharmacist about whether the current science supports trying it.
How safe is it?
Some data gaps
L-Ergothioneine appears well tolerated in foods and short-term studies, but long-term safety when taken as a supplement hasn't been firmly established. If you're pregnant, the safety data on supplement doses isn't sufficient — it's best to avoid it.
If you're breastfeeding, safety hasn't been studied, so supplemental use is not recommended. Talk to your pharmacist or doctor before starting if either applies to you.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. That said, run your medications through the search tool on this page — it's always smart to verify before you start anything new.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.
This product may interest you if you're exploring L-Ergothioneine for heart or joint health, but the evidence is still developing. Pregnant or nursing women should skip it.
If you have questions about whether it fits your health routine, your pharmacist can help you sort it out.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Ergothioneine, straight from the product label.
| Brand | Absonutrix |
|---|---|
| Barcode (UPC) | 685167904790 |
| Net contents | 4 Fluid Ounce(s); 118 mL |
| Market status | On market |
| Date entered into DSLD | Jan 23, 2025 |
| DSLD ID | 322360 |
| Product type | Amino Acid/protein |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Ergothioneine by Absonutrix, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Ergothioneine | 0 NP | -- |
| L-Ergothioneine | 590 mg | -- |
| Oyster Mushroom Extract | 0 NP | -- |
Other ingredients: Water, Distilled, Ethanol, Potassium Sorbate, Stevia, Peppermint Oil
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: shake well before use. Take 12 drops once daily. Hold in mouth for 15 seconds and then swallow. If supplement flavour is too strong, add it into a preferred drink like water or juice and consume.
Precautions
Caution: for adults only. Keep out of reach of children.
Consult a physician if you are pregnant/nursing, taking any medications, or have a medical condition.
In the unlikely event that you do experience any side effects or allergies, stop use immediately and promptly seek medical attention.
Keep out of the reach of children.
Do not use if safety seal is damaged or missing.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Highest quality ingredients Powerful formula Made in USA
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Made in USA
General Statements
Please recycle
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Ergothioneine by Absonutrix label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Ergothioneine by Absonutrix
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.59 mL Dosage formLiquid Servings per container200 Amounts shown are per serving.
L-Ergothioneine
No knowninteractions
Ergothioneine is a naturally occurring amino acid–like compound (an antioxidant) found mostly in mushrooms and made by certain fungi and bacteria. Ear...
L-Ergothioneine monograph & interactions- › L-Ergothioneine
- › Oyster Mushroom Extract
Other (inactive) ingredients: Water, Distilled, Ethanol, Potassium Sorbate, Stevia, Peppermint Oil. These complete the product’s ingredient list but are not active constituents.
L-Ergothioneine by Absonutrix Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in L-Ergothioneine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for L-Ergothioneine, from the product label.
Absonutrix
See all Absonutrix products- Name
- Absonutrix
- Street Address
- 8905 West Market Street
- City
- Colfax
- State
- NC
- ZipCode
- 27235
- Phone Number
- 1-855-368-8749
- Web Address
- www.absonutrix.com
L-Ergothioneine by Absonutrix: Common Questions
Does L-Ergothioneine by Absonutrix interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is L-Ergothioneine proven to work for heart health or joint pain?
Can I take this if I'm pregnant or breastfeeding?
What are the side effects?
What is L-Ergothioneine?
Does this have any fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Ergothioneine is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Ergothioneine’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
L-Ergothioneine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 2 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Ergothioneine 2 references
- Benson KF, Ager DM, Landes B, Aruoma OI, Jensen GS. Improvement of joint range of motion (ROM) and reduction of chronic pain after consumption of an ergothioneine-containing nutritional supplement. Prev Med. 2012;54 Suppl:S83-9. PubMed
- Smith E, Ottosson F, Hellstrand S, et al. Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease. Heart 2019. pii: heartjnl-2019-315485. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC