Interactions on record — worth a quick check against your medications. Based on 4 of 8 ingredients. Check your meds →
Dietary supplement

Pro-Series Build Peach Mango Ingredients & Drug Interactions

by Jacked Factory

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Pro-Series Build Peach Mango is a dietary supplement by Jacked Factory with 8 active ingredients. Its ingredients are commonly taken for fatigue and low energy, athletic performance and stamina, respiratory and lung support.Based on those ingredients, 662 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi, Lion's Mane, Shiitake. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Pro-Series Build Peach Mango by Jacked Factory

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 8 active ingredients.
  • “Peak02” is listed as a grouped ingredient — the label gives one combined amount (2,000 mg) without saying how much of each component you get.

Pro-Series Build Peach Mango is a powder with 8 active ingredients designed to support athletic performance and muscle building. The active ingredients are cordyceps, lion's mane mushroom, shiitake mushroom, hydroxyisocaproic acid (HICA), reishi mushroom, Peak02 (a mushroom blend), Turkey Tail mushroom, and elevATP.

The product also contains several inactive ingredients—citric acid, malic acid, natural flavors, calcium silicate, silicon dioxide, sucralose, and beta carotene—which are fillers, acids, and colorants that give the powder its taste, texture, and shelf stability.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: optimize athletic performance strength endurance recovery.
  • We looked for evidence on: Athletic performance, Fatigue, Muscle strength, Exercise capacity, Post-workout recovery.
  • The closest evidence on file: Cordyceps is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Cordyceps is rated "Insufficient Reliable Evidence To Rate" for Fatigue.
  • Also on file: Reishi Mushroom is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Chronic fatigue syndrome (CFS), Cancer-related fatigue.

The evidence supporting these ingredients is limited. Cordyceps is rated possibly ineffective for athletic performance, the main use for this product, and insufficient evidence exists for sexual function, heart rhythm, asthma, lung cancer, and COPD.

Lion's mane, shiitake, reishi, and the other ingredients in this formula don't have established effectiveness ratings in our data for athletic performance or muscle building. While these mushrooms have been studied for other purposes—lion's mane for cognition, reishi for blood pressure and cholesterol, shiitake for cancer—the evidence doesn't support their use for those goals either.

If you're considering this product specifically for workout support, the data we hold shows the ingredients lack proven benefit for that purpose.

The evidence, ingredient by ingredient Cordyceps Lion's Mane Mushroom Shiitake Mushroom Reishi Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cordyceps and reishi are generally well tolerated short-term, though long-term safety data is limited. Lion's mane is generally well tolerated as a food, but long-term supplement safety hasn't been well studied.

Shiitake is generally safe as a cooked food, but concentrated supplements carry more risk—raw shiitake can cause shiitake dermatitis (a distinctive skin rash) and rarely intestinal blockage; contact with the mushroom can trigger allergic reactions including asthma and, in workers, hypersensitivity pneumonitis with breathing problems and chest pain. Common side effects reported across the mushroom ingredients include gastrointestinal upset (nausea, diarrhea, constipation, abdominal discomfort, bloating), dry mouth, dizziness, and rash.

A rare case of liver inflammation (hepatitis) has been reported with cordyceps, though it's unclear whether cordyceps or a contaminant was responsible. Reishi can cause itching, and all are best avoided in pregnancy and while breastfeeding because safety data is insufficient.

Side effects, ingredient by ingredient Cordyceps Lion's Mane Mushroom Shiitake Mushroom Reishi Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Cordyceps, Shiitake Mushroom, Reishi Mushroom, Lion's Mane Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 662 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take blood thinners or antiplatelet drugs (like warfarin or aspirin), check first with your pharmacist or doctor—cordyceps and lion's mane may increase bleeding risk. If you're on immunosuppressants (including cyclosporine), diabetes medications, antihypertensive drugs (blood pressure drugs), or drugs metabolized by your liver's CYP2D6 enzyme, talk it over before adding this product.

Use the medication checker on this page to search your specific prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Pro-Series Build Peach Mango is a mushroom-based powder marketed for athletic performance, but the evidence that cordyceps or the other ingredients actually improve workout results is weak or absent in our data. More importantly, if you take blood thinners, diabetes medications, immunosuppressants, or blood pressure drugs, the mushroom ingredients here have documented Moderate interactions that could affect how those medications work.

Before starting this product, check your exact medications with your doctor or pharmacist—don't rely on this product alone to guide that decision.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pro-Series Build Peach Mango, straight from the product label.

Brand Jacked Factory
Barcode (UPC) X002LJJ6S1
Net contents 13.1 Ounce(s); 372 Gram(s)
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 261412
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pro-Series Build Peach Mango by Jacked Factory, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6.2 Gram(s)
Maximum serving Sizes:
12.4 Gram(s)
Servings per container
60
UPC/BARCODE
X002LJJ6S1
IngredientAmount% DV
King Trumpet0 NP--
Cordyceps0 NP--
Lion's Mane0 NP--
Calories10 Calorie(s)--
Shiitake0 NP--
Hydroxyisocaproic Acid750 mg--
Reishi0 NP--
Total Carbohydrates2 Gram(s)1%
Peak022000 mg--
Turkey Tail0 NP--
elevATP150 mg--

Other ingredients: Citric Acid, Malic Acid, Natural Flavors, Calcium Silicate, Silicon Dioxide, Sucralose, Beta Carotene

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Pro-Series Build is an elite muscle-building formula designed to optimize your athletic performance, strength, endurance, and recovery.

These ingredients have been shown in clinical research to significantly improve strength, power, endurance, blood flow, and oxygen uptake in as little as one week.

Pro-Series Build allows you to break limits in the trenches and perform at peak capacity every single training session. Best of all, Pro-Series Build is a stimulant-free formula that you can stack with your favorite pre-workout, intra-workout, and post-workout supplements for even greater results.

Best of all, Pro-Series Build is a stimulant-free formula that you can stack with your favorite pre-workout, intra-workout, and post-workout supplements for even greater results.

Lean muscle builder Optimize athletic performance Rapid ATP booster Increase strength Elite muscle-building formula

Formula

Featuring clinical doses of PeakO2, ElevATP, and Hydroxy-Isocaproic Acid (HICA), Pro-Series Build is revolutionizing performance supplementation for athletes, bodybuilders, and gym-goers alike.

150 mg ElevATP 750 mg Hydroxy-Isocaproic acid 2000 mg PeakO2

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, mix 1-2 scoops with 8-10 oz of water 30-40 minutes before your workout. Do not exceed 2 scoops in a 24 hour period. 1 Scoop I 2 Scoops - 8-10 oz water - 30-40 mins

Precautions

Warning: Consult your physician prior to using this product if you are pregnant, nursing, under 18 years of age, taking medication or have a medical condition.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, under 18 years of age, taking medication or have a medical condition.

Immediately discontinue use and contact your physician if any adverse reactions occur.

Keep out of reach of children.

Storage

Store in a cool, dry place away from excessive heat.

General Statements

Get connected Facebook @JackedFactory Instagram @Jacked_Factory

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

ElevATP is a registered trademark material of Futureceuticals PeakO2 is protected by patents pending owned by Disruptive Nutrition, LLC and under exclusive global distribution by Compound Solutions, Inc.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Pro-Series Build Peach Mango by Jacked Factory label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pro-Series Build Peach Mango by Jacked Factory

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size6.2 Gram(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Hydroxyisocaproic Acid

750 mg per serving

Peak02

2000 mg per serving

ElevATP

150 mg per serving Form: Ancient Peat, Apple Extract

Other (inactive) ingredients: Citric Acid, Malic Acid, Natural Flavors, Calcium Silicate, Silicon Dioxide, Sucralose, Beta Carotene. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pro-Series Build Peach Mango by Jacked Factory Drug Interactions

Want to check YOUR meds against Pro-Series Build Peach Mango?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
662Drugs
654 Moderate 8 Minor

Ingredients driving the most interactions

Reishi 375
Shiitake 312
Cordyceps 249

Each ingredient & the kinds of drugs it affects

For each ingredient in Pro-Series Build Peach Mango with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Reishi3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D

Lion's Mane3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D

Shiitake2 drug types · 312 drugs

Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
In vitro studies suggest that the shiitake mushroom extract AHCC might induce the CYP2D6 enzyme. This effect has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking shiitake mushroom might decrease the effects of immunosuppressive therapy.
In vitro evidence suggests that shiitake mushroom extracts stimulate immune function.

Likelihood Possible Evidence D

Cordyceps3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Pro-Series Build Peach Mango, from the product label.

Jacked Factory

See all Jacked Factory products
Name
Jacked Factory
City
St. John's
ZipCode
A1A 5A1
Phone Number
1-877-250-5237
Web Address
Jackedfactory.com
Pharmacist Counseling Corner

Pro-Series Build Peach Mango by Jacked Factory: Common Questions

Does Pro-Series Build Peach Mango by Jacked Factory interact with any medications?
Yes. Based on its ingredients, Pro-Series Build Peach Mango has a known interaction with 662 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pro-Series Build Peach Mango contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
The safety data for cordyceps, lion's mane, shiitake, and reishi in pregnancy and breastfeeding is not sufficient to know either way. The facts advise avoiding them during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you in those situations.
Will this actually help me build muscle or improve my workouts?
Cordyceps, the ingredient most likely linked to athletic performance, is rated possibly ineffective in our data. The other mushroom ingredients don't have established effectiveness ratings for muscle building or athletic performance either. The evidence supporting this product's claims is not strong.
What are the most common side effects I might notice?
Gastrointestinal upset is most common—nausea, diarrhea, constipation, abdominal discomfort, and bloating. You might also experience dizziness, dry mouth, itching, or rash. Taking cordyceps with food can help reduce some GI symptoms. These side effects tend to be uncommon, though the mushroom ingredients haven't been studied long-term.
Is this product safe to use long-term?
Long-term safety data is limited for all the mushroom ingredients in this formula. Cordyceps and reishi are noted as generally well tolerated short-term, but long-term use hasn't been well studied. If you're thinking about using this for weeks or months, ask your doctor or pharmacist whether it's appropriate for your situation.
Why can't you check King Trumpet, Turkey Tail, and some other ingredients?
We don't hold monographs or interaction data for King Trumpet, Turkey Tail, Hydroxyisocaproic Acid, or elevATP, so we can't tell you whether they interact with medications. Peak02 is a branded blend, and we've covered its component mushrooms separately. That's why checking your specific medications with a pharmacist is so important.
What is cordyceps supposed to do?
Cordyceps is marketed for athletic performance, sexual function, and respiratory health, but our data rates it possibly ineffective for athletic performance and insufficient evidence for the others. It's generally well tolerated when used up to a year, though digestive upset, dry mouth, and throat discomfort can occur.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pro-Series Build Peach Mango is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pro-Series Build Peach Mango label
Sources

Sources & How We Checked

Pro-Series Build Peach Mango's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 104 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
  2. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
  3. Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
  4. Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
  5. Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
  6. Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
  7. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
  8. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
  9. Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
  10. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
  11. Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
  12. Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
  13. Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
  14. Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.

See these in context on the Cordyceps monograph →

Lion's Mane Mushroom 6 references
  1. Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
  2. Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
  4. Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
  5. Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
  6. Tian B, Liu R, Xu T, et al. Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide-treated mice. J Sci Food Agric 2023;103(6):3050-3064.

See these in context on the Lion's Mane Mushroom monograph →

Shiitake Mushroom 67 references
  1. Hitosugi M, Kitamura O, Takatsu A, Yoshino Y. Autopsy case of duodenal obstruction from impacted mushroom. J Gastroenterol 1998;33:562-5. PubMed
  2. Hanada K, Hashimoto I. Flagellate mushroom (Shiitake) dermatitis and photosensitivity. Dermatol 1998;197:255-7. PubMed
  3. Levy AM, Kita H, Phillips SF, et al. Eosinophilia and gastrointestinal symptoms after ingestion of shiitake mushrooms. J Allergy Clin Immunol 1998;101:613-20. PubMed
  4. Murakami M, Kawabe K, Hosoi Y, et al. Decreased pulmonary perfusion in hypersensitivity pneumonitis caused by Shiitake mushroom spores. J Intern Med 1997;241:85-8. PubMed
  5. Matsui S, Nakazawa T, Umegae Y, Mori M. Hypersensitivity pneumonitis induced by Shiitake mushroom spores. Intern Med 1992;31:1204-6.
  6. Nakamura T. Shiitake (Lentinus edodes) dermatitis. Contact Dermatitis 1992;27:65-70.
  7. Ueda A, Obama K, Aoyama K, et al. Allergic contact dermatitis in shiitake (Lentinus edodes (Berk) Sing) growers. Contact Dermatitis 1992;26:228-33.
  8. Burikhanov, R. B., Wakame, K., Igarashi, Y., Wang, S., and Matsuzaki, S. Suppressive effect of active hexose correlated compound (AHCC) on thymic apoptosis induced by dexamethasone in the rat. Endocr.Regul. 2000;34(4):181-188.
  9. Gao, Y., Zhang, D., Sun, B., Fujii, H., Kosuna, K., and Yin, Z. Active hexose correlated compound enhances tumor surveillance through regulating both innate and adaptive immune responses. Cancer Immunol.Immunother. 2006;55(10):1258-1266. PubMed
  10. Ritz, B. W., Nogusa, S., Ackerman, E. A., and Gardner, E. M. Supplementation with active hexose correlated compound increases the innate immune response of young mice to primary influenza infection. J Nutr. 2006;136(11):2868-2873. PubMed
  11. Aviles, H., O'Donnell, P., Sun, B., and Sonnenfeld, G. Active hexose correlated compound (AHCC) enhances resistance to infection in a mouse model of surgical wound infection. Surg.Infect.(Larchmt.) 2006;7(6):527-535. PubMed
  12. Spierings, E. L., Fujii, H., Sun, B., and Walshe, T. A Phase I study of the safety of the nutritional supplement, active hexose correlated compound, AHCC, in healthy volunteers. J Nutr Sci Vitaminol.(Tokyo) 2007;53(6):536-539. PubMed
  13. Aviles, H., O'Donnell, P., Orshal, J., Fujii, H., Sun, B., and Sonnenfeld, G. Active hexose correlated compound activates immune function to decrease bacterial load in a murine model of intramuscular infection. Am J Surg. 2008;195(4):537-545. PubMed
  14. Ritz, B. W. Supplementation with active hexose correlated compound increases survival following infectious challenge in mice. Nutr.Rev. 2008;66(9):526-531. PubMed
  15. Terakawa, N., Matsui, Y., Satoi, S., Yanagimoto, H., Takahashi, K., Yamamoto, T., Yamao, J., Takai, S., Kwon, A. H., and Kamiyama, Y. Immunological effect of active hexose correlated compound (AHCC) in healthy volunteers: a double-blind, placebo-controll
  16. Mach, C. M., Fugii, H., Wakame, K., and Smith, J. Evaluation of active hexose correlated compound hepatic metabolism and potential for drug interactions with chemotherapy agents. J Soc Integr.Oncol. 2008;6(3):105-109.
  17. Wang, S., Welte, T., Fang, H., Chang, G. J., Born, W. K., O'Brien, R. L., Sun, B., Fujii, H., Kosuna, K., and Wang, T. Oral administration of active hexose correlated compound enhances host resistance to West Nile encephalitis in mice. J Nutr. 2009;139(3 PubMed
  18. Sumiyoshi, Y., Hashine, K., Kakehi, Y., Yoshimura, K., Satou, T., Kuruma, H., Namiki, S., and Shinohara, N. Dietary administration of mushroom mycelium extracts in patients with early stage prostate cancers managed expectantly: a phase II study. Jpn.J Cl PubMed
  19. Yin, Z., Fujii, H., and Walshe, T. Effects of active hexose correlated compound on frequency of CD4+ and CD8+ T cells producing interferon-gamma and/or tumor necrosis factor-alpha in healthy adults. Hum.Immunol. 2010;71(12):1187-1190.
  20. Lee, W. W., Lee, N., Fujii, H., and Kang, I. Active Hexose Correlated Compound promotes T helper (Th) 17 and 1 cell responses via inducing IL-1beta production from monocytes in humans. Cell Immunol. 2012;275(1-2):19-23.
  21. Daddaoua, A., Martinez-Plata, E., Ortega-Gonzalez, M., Ocon, B., Aranda, C. J., Zarzuelo, A., Suarez, M. D., de Medina, F. S., and Martinez-Augustin, O. The nutritional supplement Active Hexose Correlated Compound (AHCC) has direct immunomodulatory actio
  22. Roman, B. E., Beli, E., Duriancik, D. M., and Gardner, E. M. Short-term supplementation with active hexose correlated compound improves the antibody response to influenza B vaccine. Nutr Res. 2013;33(1):12-17. PubMed
  23. Uno, K., Kosuna, K., Sun, B., Fujii, H., Wakame, K., Chikumaru, S., Hosokawa, G., and Ueda, Y. Active Hexose Correlated Compound (AHCC) Improves Immunological Parameters and Performance Status of Patients with Solid Tumors. Biotherapy 2000;14(3):303-309.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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