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Dietary supplement

L-Lysine 1000 mg Ingredients & Drug Interactions

by Viva Vitamins

Tablet Or Pill Category: Amino Acid/protein
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

L-Lysine 1000 mg is a dietary supplement by Viva Vitamins with 1 active ingredient. Its ingredients are commonly taken for cold sores (herpes labialis), genital herpes outbreaks, supporting protein and collagen formation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated minor. The ingredients most likely to interact are L-Lysine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of L-Lysine 1000 mg by Viva Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-lysine, an amino acid your body needs for protein synthesis, immune function, and tissue repair. Each tablet delivers 1000 mg.

The tablet also includes several inactive ingredients — cellulose, stearin, cellulose gum, magnesium stearate, and silica — which are fillers and binders that help form and stabilize the pill.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Skin support, immune function, and bone health.
  • We looked for evidence on: Herpes labialis (cold sores), Collagen synthesis, Wound healing, Immune support.
  • The strongest evidence on file: Lysine is rated "Possibly Effective" for Herpes labialis (cold sores) (Natural Medicines).

L-lysine is possibly effective for cold sores (herpes labialis). For other uses — child growth, pressure ulcers, and diabetic foot ulcers — we don't have enough reliable evidence to rate how well it works.

Talk with your doctor about whether it fits your situation.

The evidence, ingredient by ingredient Lysine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-lysine from food is fine, but at high supplement doses it may cause stomach upset, diarrhea, or indigestion. Long-term safety from supplements isn't well studied.

Supplement use in pregnancy and breastfeeding hasn't been well researched, so check with your doctor or pharmacist before taking it if you're pregnant or nursing. There is one rare case report of kidney damage linked to oral lysine, though this is not common.

Side effects, ingredient by ingredient Lysine

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lysine.
  • The most serious interaction on file is rated Minor.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take a 5-HT4 agonist (a medication for stomach or bowel conditions), check with your pharmacist before starting L-lysine — it may reduce how well that drug works. For any other medications, run them through the checker below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

L-lysine may help with cold sores if you're willing to try a supplement with modest evidence. If you're pregnant, breastfeeding, or take any medications — especially stomach medications — talk to your pharmacist first.

Otherwise, it's generally well tolerated at regular doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Lysine 1000 mg, straight from the product label.

Brand Viva Vitamins
Barcode (UPC) 812720015697
Net contents 100 Tablet(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 316307
Product type Amino Acid/protein
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Lysine 1000 mg by Viva Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
100
UPC/BARCODE
812720015697
IngredientAmount% DV
L-Lysine1000 mg--

Other ingredients: Cellulose, Stearin, Cellulose Gum, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one (1) tablet daily. For extra skin support during these stressful times, take one (1) tablet, three (3) times daily, or as directed by a health care professional.

Formula

Lysine is required for collagen synthesis (which benefits the skin). It also plays a role in immune function, and may be important to bone health.

Free Form Amino Acid

Our L-Lysine is a pure crystalline, free form amino acid.

Storage

Store in a cool dry place. Do not refrigerate.

General Statements

Please Recycle

For more information visit www.vivavitamins.com In God We Trust

Precautions

Do not use if safety seal under cap is broken or missing.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Copyright 2013

Formulation

Made in the USA GMP Compliant Manufacturing

Supports immune function & collagen synthesis/skin health

Contains No: Gluten, sugar, salt, yeast, corn, wheat, lactose, citrus, milk, egg, fish products, artificial coloring, flavoring or preservatives.

FDA Statement of Identity

Dietary Supplement

See for yourself

L-Lysine 1000 mg by Viva Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Lysine 1000 mg by Viva Vitamins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container100 Amounts shown are per serving.

L-Lysine

Interacts with
1 drug
1000 mg per serving Form: L-Lysine Hydrochloride

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...

L-Lysine monograph & interactions

Other (inactive) ingredients: Cellulose, Stearin, Cellulose Gum, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Lysine 1000 mg by Viva Vitamins Drug Interactions

Want to check YOUR meds against L-Lysine 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Lysine 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Lysine1 drug type · 1 drug

5-Ht4 Agonists

Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for L-Lysine 1000 mg, from the product label.

Viva Vitamins

Name
Viva Vitamins
Street Address
25908 McBean Pkwy
City
Valencia
State
CA
ZipCode
91355
Web Address
www.vivavitamins.com
Pharmacist Counseling Corner

L-Lysine 1000 mg by Viva Vitamins: Common Questions

Does L-Lysine 1000 mg by Viva Vitamins interact with any medications?
Yes. Based on its ingredients, L-Lysine 1000 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Lysine 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will L-lysine help my cold sores?
L-lysine is possibly effective for cold sores, so there's some evidence it may help — but it's not proven to work for everyone. You may want to try it and see if you notice improvement, or talk to your doctor about whether it makes sense for you.
What side effects should I watch for?
Most people tolerate L-lysine well, but some report stomach pain, diarrhea, or indigestion, especially at higher doses. Long-term safety from supplements hasn't been deeply studied, so if you take it regularly and feel off, let your pharmacist know.
Is it safe to take while pregnant?
Lysine from food is fine, but we don't have enough data on supplement safety in pregnancy. Talk with your doctor before starting it — they can weigh the pros and cons for your situation.
What about breastfeeding?
There isn't enough reliable information on L-lysine supplements during breastfeeding, so caution is advised. Check with your doctor or pharmacist before taking it if you're nursing.
What does L-lysine actually do in my body?
L-lysine is an amino acid your body uses to build and repair proteins, support your immune system, and maintain healthy tissues. You get it from food like meat, dairy, and legumes, but some people take it as a supplement for specific uses like cold sores.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Lysine 1000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Lysine 1000 mg label
Go deeper

The Full Monographs Behind L-Lysine 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Lysine 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lysine 7 references
  1. Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
  2. McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
  3. DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
  4. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
  5. Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
  6. Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
  7. Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.

See these in context on the Lysine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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