L-Lysine Basics Ingredients & Drug Interactions
by MRM
What is this page for?
First and foremost: checking L-Lysine Basics against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Lysine Basics is a dietary supplement by MRM with 1 active ingredient. Its ingredients are commonly taken for cold sores (herpes labialis), genital herpes outbreaks, supporting protein and collagen formation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated minor. The ingredients most likely to interact are L-Lysine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against L-Lysine Basics by MRM
Ask about any prescription or over-the-counter medication and we check it for interactions with L-Lysine Basics by MRM — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of L-Lysine Basics by MRM
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
L-Lysine Basics contains one active ingredient: L-lysine, an amino acid your body needs to build protein. The capsule also contains rice flour as an inactive ingredient.
Does it work?
Moderate evidence
L-lysine is possibly effective for cold sores (herpes labialis). For other uses listed — child growth, pressure ulcers, and diabetic foot ulcers — the evidence isn't established well enough to rate it.
How safe is it?
Well-documented data
L-lysine is generally well tolerated at normal doses. High amounts may cause stomach upset, and long-term safety at high levels isn't well studied.
The most common side effects from taking it by mouth are abdominal pain, diarrhea, and indigestion. There's one reported case of kidney damage linked to oral lysine use, though it's rare.
Lysine from food is fine during pregnancy, but supplement safety during pregnancy isn't well studied — talk with your doctor before taking this as a supplement if you're pregnant. There also isn't enough reliable information on supplement use while breastfeeding, so caution is advised and it's worth discussing with your doctor or pharmacist.
Meds to double-check
Minor interactions only
Check with your doctor or pharmacist if you take a 5-HT4 agonist — lysine may reduce how well it works. No other medication interactions are documented in our data for L-lysine.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.
L-Lysine Basics may help with cold sores. If you take a 5-HT4 agonist, check with your doctor or pharmacist first — this supplement may interfere with it.
Otherwise, it's generally well tolerated at typical doses, though high amounts can upset your stomach.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 26, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Lysine Basics, straight from the product label.
| Brand | MRM |
|---|---|
| Barcode (UPC) | 60949285005 |
| Net contents | 60 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 26, 2014 |
| DSLD ID | 36938 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Lysine Basics by MRM, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
DIETARY SUPPLEMENT
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure or prevent any disease.
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Suggested/Recommended/Usage/Directions
Suggested Usage: Take 1 capsule up to 3 times a day or as directed by your qualified healthcare provider.
Formulation
Contains NO milk, egg, peanut, tree nut, fish, shellfish, soy, wheat, gluten or yeast.
~Excellent L-Lysine Source for Vegans/Vegetarians
General Statements
MADE IN THE USA
L-Lysine is an essential amino acid, which means that it cannot be manufactured by the body and must be obtained through the diet or by supplementation. Some vegans/vegetarians or athletic individuals have an increased need for essential amino acids. L-Lysine is a necessary building block for the production of hormones, enzymes, collagen and immune system proteins, while also playing a role in calcium bioavailability
~Supports Healthy Immune Function ~Essential Amino Acid
~500mg Per Capsule ~Essential Amino Acid
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Lysine Basics by MRM label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Lysine Basics by MRM
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
L-Lysine
Interacts with1 drug
Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...
L-Lysine monograph & interactionsOther (inactive) ingredients: Rice Flour, Capsule. These complete the product’s ingredient list but are not active constituents.
L-Lysine Basics by MRM Drug Interactions
HelloPharmacist Interaction Report
L-Lysine Basics by MRM contains L-lysine, which has one documented interaction — a Minor interaction with 5-HT4 agonists (medications that work through serotonin receptor 4).
Animal research suggests lysine may reduce how well these drugs work by partially blocking that receptor.
Read the full breakdown — every affected drug type, severity by severity
If you take a 5-HT4 agonist, mention this product to your doctor or pharmacist before starting. They can let you know if the interaction matters for your specific situation.
You can use the medication checker below to see if any of your prescriptions fall into that category.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against L-Lysine Basics?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in L-Lysine Basics interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in L-Lysine Basics interact with drugs. Each result below shows which ingredient is responsible. L-Lysine
TegaserodZelnorm
How Tegaserod interacts with L-Lysine Basics — through 1 ingredient. Tap an ingredient for the detail:
L-lysine5-ht4 Agonists Minor
Interaction Summary
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Read the full L-lysine + Tegaserod interactionEach ingredient & the kinds of drugs it affects
For each ingredient in L-Lysine Basics with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Lysine
5-Ht4 Agonists
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.
Brand information
Manufacturer and brand details for L-Lysine Basics, from the product label.
MRM
See all MRM products- Name
- MRM
- Street Address
- 2665 Vista Pacific Dr.
- City
- Oceanside
- State
- CA
- ZipCode
- 92056
- Phone Number
- 1-800-948-6296
- Web Address
- www.mrm-usa.com
L-Lysine Basics by MRM: Common Questions
Does L-Lysine Basics by MRM interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does L-lysine actually work for cold sores?
What are the side effects of L-lysine?
Is it safe to take L-lysine while pregnant?
Can I take L-lysine while breastfeeding?
What is L-lysine and what does it do?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Lysine Basics is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Lysine Basics’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
L-Lysine Basics's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lysine 7 references
- Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
- McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
- DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
- Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
- Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
- Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
- Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC