L-Lysine HCl Ingredients & Drug Interactions
by Biotics Research Corporation
What is this page for?
First and foremost: checking L-Lysine HCl against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Lysine HCl is a dietary supplement by Biotics Research Corporation with 1 active ingredient. Its ingredients are commonly taken for cold sores (herpes labialis), genital herpes outbreaks, supporting protein and collagen formation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated minor. The ingredients most likely to interact are L-Lysine Hydrochloride. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against L-Lysine HCl by Biotics Research Corporation
Ask about any prescription or over-the-counter medication and we check it for interactions with L-Lysine HCl by Biotics Research Corporation — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of L-Lysine HCl by Biotics Research Corporation
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This supplement contains one active ingredient: L-lysine hydrochloride, an amino acid form of lysine. The capsule also holds gelatin, water, and glycerin as inactive ingredients to hold it together and make it swallowable.
Does it work?
Moderate evidence
L-lysine is possibly effective for cold sores (herpes labialis) — the evidence supports a role here, though it's not ironclad. For child growth, pressure ulcers, and diabetic foot ulcers, the evidence we hold is insufficient to say whether it works.
How safe is it?
Well-documented data
Lysine is generally well tolerated at typical doses. High amounts may cause stomach upset, and long-term safety hasn't been thoroughly studied.
The most common side effects from oral use are abdominal pain, diarrhea, and indigestion. There's one rare case report of kidney inflammation linked to lysine, but it's not a known pattern.
Lysine from food is safe in pregnancy, but supplement safety during pregnancy and breastfeeding hasn't been well studied — talk with your doctor before taking this if you're pregnant or nursing.
Meds to double-check
Minor interactions only
Before taking this product, double-check if you're on a 5-HT4 agonist — a medication that can improve certain bowel symptoms. Lysine may reduce how well it works.
If you're unsure whether your medication is in that class, ask your pharmacist or doctor to confirm before you start.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.
L-lysine is worth considering if you get frequent cold sores and want an amino acid supplement with some evidence behind it. If you take any digestive medications (especially 5-HT4 agonists), check with your doctor or pharmacist first.
Pregnant or breastfeeding — same thing: run it by your healthcare provider before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Lysine HCl, straight from the product label.
| Brand | Biotics Research Corporation |
|---|---|
| Net contents | 100 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2013 |
| DSLD ID | 21941 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Lysine HCl by Biotics Research Corporation, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Lysine Hydrochloride | 500 mg | -- |
Other ingredients: Gelatin, Water, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
CERTIFIED PURE
Suggested/Recommended/Usage/Directions
RECOMMENDATION: One (1) capsule (3) times each day as a dietary supplement or as otherwise directed by a healthcare professional.
Precautions
KEEP OUT OF REACH OF CHILDREN
Sealed with an imprinted safety seal for your protection.
Storage
Store in a cool, dry area.
General
Rev. 1/08
FDA Statement of Identity
Amino Acid Supplement
Brand IP Statement(s)
(C) Copyright 2010
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Lysine HCl by Biotics Research Corporation label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Lysine HCl by Biotics Research Corporation
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
L-Lysine Hydrochloride
Interacts with1 drug
Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...
L-Lysine Hydrochloride monograph & interactionsOther (inactive) ingredients: Gelatin, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.
L-Lysine HCl by Biotics Research Corporation Drug Interactions
HelloPharmacist Interaction Report
L-Lysine HCl by Biotics Research Corporation has one documented interaction — a Minor interaction with 5-HT4 agonists (a type of medication used for certain digestive and bowel conditions).
Animal research suggests lysine may work against how these drugs are supposed to function, potentially reducing their effects.
Read the full breakdown — every affected drug type, severity by severity
Altogether, these interactions span 1 individual medication.
If you take a 5-HT4 agonist, run it through the medication checker on this page before starting lysine. Your doctor or pharmacist can tell you whether the timing or dose needs adjusting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against L-Lysine HCl?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in L-Lysine HCl interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in L-Lysine HCl interact with drugs. Each result below shows which ingredient is responsible. L-Lysine Hydrochloride
TegaserodZelnorm
How Tegaserod interacts with L-Lysine HCl — through 1 ingredient. Tap an ingredient for the detail:
L-lysine Hydrochloride5-ht4 Agonists Minor
Interaction Summary
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Read the full L-lysine Hydrochloride + Tegaserod interactionEach ingredient & the kinds of drugs it affects
For each ingredient in L-Lysine HCl with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Lysine Hydrochloride
5-Ht4 Agonists
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.
Brand information
Manufacturer and brand details for L-Lysine HCl, from the product label.
Biotics Research Corporation
See all Biotics Research Corporation products- Name
- BIOTICS RESEARCH CORP.
- City
- Rosenberg
- State
- Texas
- Phone Number
- (281) 344-0909
L-Lysine HCl by Biotics Research Corporation: Common Questions
Does L-Lysine HCl by Biotics Research Corporation interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does L-lysine actually work for cold sores?
What are the side effects?
Is it safe to take L-lysine if I'm pregnant?
What about while breastfeeding?
Can I take this with other supplements or medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Lysine HCl is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Lysine HCl’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
L-Lysine HCl's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lysine 7 references
- Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
- McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
- DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
- Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
- Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
- Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
- Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC