No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Proline Ingredients & Drug Interactions

by NutraBio

Powder Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Proline is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for joint and connective tissue support, skin health and wound healing, collagen production.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Proline by NutraBio

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-proline, an amino acid your body uses to build and repair connective tissue, including collagen in skin, joints, and bone. It's naturally present in protein-rich foods, and this powder form lets you add extra amounts to your routine if you choose.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Proline product and its label doesn't state a use — see Proline's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for L-proline on athletic performance, bone health (osteoporosis, osteopenia, and fractures), and wound healing is insufficient right now — we don't have reliable data showing it works for any of these. That doesn't mean it doesn't; it means the studies aren't there yet to confirm benefit.

The evidence, ingredient by ingredient Proline

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-proline from food sources is generally well tolerated. The safety of supplemental doses, though, hasn't been well studied, so the facts suggest avoiding extra amounts unless your doctor recommends them.

If you're pregnant, there isn't enough data to know whether supplemental doses are safe — talk with your doctor or pharmacist about whether this is right for you. The same goes for breastfeeding: safety data on supplemental doses isn't established, so use caution and check with your doctor or pharmacist first.

Side effects, ingredient by ingredient Proline

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for L-proline. Still, check your exact medications with the search tool on this page or with your doctor or pharmacist before adding any new supplement to your routine.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.

L-Proline is a single amino acid with no documented drug interactions. If you're interested in it for joint or connective-tissue support, keep in mind the evidence isn't strong enough yet to confirm it works.

Talk with your doctor or pharmacist about whether it's a good fit for you, especially if you're pregnant, breastfeeding, or taking any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Proline, straight from the product label.

Brand NutraBio
Barcode (UPC) 649908234294
Net contents 5.3 Ounce(s); 150 Gram(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 309343
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Proline by NutraBio, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
2 Gram(s)
Servings per container
75
UPC/BARCODE
649908234294
IngredientAmount% DV
L-Proline2 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, add 1 scoop (2 grams) to your favorite beverage 1-2 times daily, or as directed by a physician.

Formulation

Vegetarian

Non-GMO Gluten free Lactose free No excipients, no fillers, allergen free, no artificial color, flavor or sweetener, no preservatives, no starch, no sugar, no soy, no wheat, no yeast, no fish, no milk, sodium free.

Supports healthy joints Supports cardiovascular function Supports collagen production

Precautions

Warning: Not intended for use by persons under the age of 18. Keep out of the reach of children.

If you are pregnant, breast feeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.

Discontinue use two weeks prior to surgery.

General Statements

NutraBio Since 1996

Seals/Symbols

Manufactured in our GMP & FDA Inspected facility FDA Registration: 16906175560

Made in USA With ingredients sourced worldwide

OU (Kosher)

Formula

Pure grade amino acid

OU (Kosher)

FDA Statement of Identity

Amino Acid Supplement

Storage

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

L-Proline by NutraBio label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Proline by NutraBio

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Servings per container75 Amounts shown are per serving.

L-Proline

No known
interactions
2 Gram(s) per serving

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of...

L-Proline monograph & interactions
Interaction report

L-Proline by NutraBio Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Proline. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Proline, from the product label.

NutraBio

See all NutraBio products
Name
NutraBio Labs, Inc.
Street Address
564 Lincoln Blvd.
City
Middlesex
State
NJ
ZipCode
08846
Phone Number
732-748-8606
Web Address
www.nutrabio.com
Pharmacist Counseling Corner

L-Proline by NutraBio: Common Questions

Does L-Proline by NutraBio interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Proline. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Proline contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is L-proline safe to take if I'm pregnant?
There isn't enough data on supplemental L-proline in pregnancy to know whether it's safe or not. Talk with your doctor or pharmacist about your specific situation before you start.
Can I take this while breastfeeding?
Safety data on supplemental doses of L-proline during breastfeeding isn't established. Use caution and check with your doctor or pharmacist first to decide if it's right for you.
Does L-proline actually help with joint health or wound healing?
The evidence isn't strong enough yet to confirm L-proline works for either of those. More reliable studies are needed.
What does L-proline do in my body?
L-proline is an amino acid your body uses to build and repair connective tissue, especially collagen in skin, joints, and bone. You get it naturally from protein-rich foods.
Are there any side effects?
No adverse effects are listed in the data we have. That said, the safety of supplemental doses hasn't been well studied, so follow the guidance to avoid extra amounts unless your doctor advises otherwise.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Proline is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Proline label
Go deeper

The Full Monographs Behind L-Proline’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Proline's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proline 4 references
  1. Jennings A, MacGregor A, Spector T, Cassidy A. Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: Evidence from discordant monozygotic twins. J Bone Miner Res. 2016;31(2):326-35. PubMed
  2. Gracia-Marco L, Bel-Serrat S, Cuenca-Garcia M, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49(6):1041-1052. PubMed
  3. Jamdar J, Rao B, Netke S, et al. Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline. J Altern Complement Med. 2004;10(6):915-6.
  4. Mehl AA, Damião AO, Viana SD, Andretta CP. Hard-to-heal wounds: a randomised trial of an oral proline-containing supplement to aid repair. J Wound Care 2021;30(1):26-31. PubMed

See these in context on the Proline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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