100% Pure L-Histidine Ingredients & Drug Interactions
by NutraBio
What is this page for?
First and foremost: checking 100% Pure L-Histidine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
100% Pure L-Histidine is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for skin conditions like eczema, anemia related to kidney disease, allergy and inflammation support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of 100% Pure L-Histidine by NutraBio
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: L-histidine hydrochloride, an amino acid your body uses for various functions including immune response and stomach acid regulation. There are no inactive fillers — it's the amino acid and nothing else.
Does it work?
Moderate evidence
L-histidine appears possibly effective for cholera according to the data we hold. For atopic dermatitis (eczema), rheumatoid arthritis, and kidney failure, the evidence is insufficient — we simply don't have enough reliable research to say whether it works.
If you're considering it for one of those conditions, talk with your doctor about what the broader clinical picture shows.
How safe is it?
Some data gaps
L-histidine from food sources is likely safe, but supplement doses — especially the concentrated amounts in a powder — haven't been well studied. The safety notes caution that we don't have solid data on higher doses, so it's best taken only if your doctor or pharmacist advises it.
L-histidine is likely safe in pregnancy and lactation, though supplement-dose safety in those states hasn't been formally established.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredient we checked. That's not a guarantee none exist, so run your exact medications through the checker below if you want extra peace of mind.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and some safety-information gaps remain.
This is a straightforward single-ingredient amino acid powder with no documented drug interactions. It's best suited for people whose doctor has recommended L-histidine supplementation for a specific reason.
Because higher supplement doses haven't been thoroughly studied, check with your pharmacist or doctor first — especially if you have kidney problems.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about 100% Pure L-Histidine, straight from the product label.
| Brand | NutraBio |
|---|---|
| Barcode (UPC) | 649908242213 |
| Net contents | 500 Gram(s); 1.1 lbs |
| Market status | On market |
| Date entered into DSLD | Oct 22, 2015 |
| DSLD ID | 51065 |
| Product type | Amino Acid/protein |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for 100% Pure L-Histidine by NutraBio, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Histidine Hydrochloride | 500 mg | -- |
Other ingredients: Absolutely None
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
1-2 servings Mixed with 8-16 oz. Favorite Beverage 1-2x daily between meals Suggested Use: As a dietary supplement, take 1-2 servings up to two times daily between meals, or as directed by your physician.
Formula
ALLERGEN FREE
Kosher, Hypoallergenic, Non-GMO, Gluten Free and BSE/TSE Free.
Kosher, Hypoallergenic, Non-GMO, Gluten Free and BSE/TSE Free.
Formulation
ALLERGEN FREE ~ NON-GMO ~ GLUTEN FREE ~ BSE/TSE FREE
ZERO Fillers or Excipients Inferior ingredients Banned substances Added sugars Proprietary Blends Hidden ingredients
No fillers No excipients No additives
Free of Harmful Impurities.
Kosher, Hypoallergenic, Non-GMO, Gluten Free and BSE/TSE Free. No added sugars, salt, preservatives, salicylates, or artificial color, flavor or fragrance.
Precautions
Warning: NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18. KEEP OUT OF THE REACH OF CHILDREN.
If you are pregnant, breast feeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.
There are no reported side effects with L-Histidine, but overly high levels of it may lead to stress and mental disorders such as anxiety. People with schizophrenia have been found to have high levels of L-Histidine.
People suffering from schizophrenia or bipolar (manic) depression should not take an L-Histidine supplement without the approval of their medical professional.
General Statements
Manufactured in a GMP & FDA inspected facility
Made in a GMP & FDA inspected facility
Free Form Amino Acid
Pharmaceutical Grade. HPLC Lab Tested for Potency.
Powder
1000 servings
SERVING SCOOP INCLUDED (MAY SETTLE TO THE BOTTOM DURING SHIPPING.)
Since 1996
Quality and purity since 1996. NutraBio manufactures in our own FDA registered & inspected GMP facility complying with FDA 21 CFR Part 111 regulations.
Brand IP Statement(s)
Amino Therapy
Seals/Symbols
TRUE LABEL FULL LABEL DISCLOSURE
OU
FDA Statement of Identity
Dietary Supplement
Storage
STORE IN A COOL DRY PLACE.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
24221-007 B20213-002
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
100% Pure L-Histidine by NutraBio label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in 100% Pure L-Histidine by NutraBio
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.5 Gram(s) Dosage formPowder Servings per container1000 Amounts shown are per serving.
L-Histidine Hydrochloride
No knowninteractions
Histidine is an essential amino acid your body needs to build proteins and to make compounds like histamine and carnosine. Most people get enough from...
L-Histidine Hydrochloride monograph & interactionsOther (inactive) ingredients: Absolutely None. These complete the product’s ingredient list but are not active constituents.
100% Pure L-Histidine by NutraBio Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in 100% Pure L-Histidine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for 100% Pure L-Histidine, from the product label.
NutraBio
See all NutraBio products- Name
- NutraBio Labs, Inc.
- Street Address
- 564 Lincoln Blvd.
- City
- Middlesex
- State
- NJ
- ZipCode
- 08846
- Phone Number
- 732-748-8606
- Web Address
- www.nutrabio.com
100% Pure L-Histidine by NutraBio: Common Questions
Does 100% Pure L-Histidine by NutraBio interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will L-histidine interact with my medications?
Is this safe to take while pregnant or breastfeeding?
Does L-histidine actually work?
What does L-histidine do in your body?
Why does the label warn about supplement doses?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if 100% Pure L-Histidine is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind 100% Pure L-Histidine’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
100% Pure L-Histidine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC