No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

100% Pure L-Proline 2000 Milligrams Ingredients & Drug Interactions

by NutraBio

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

100% Pure L-Proline 2000 Milligrams is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for joint and connective tissue support, skin health and wound healing, collagen production.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of 100% Pure L-Proline 2000 Milligrams by NutraBio

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-Proline, an amino acid that's a building block for collagen in your body. You get 2,000 milligrams per serving.

The capsule itself is made from vegetable material.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Proline's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: collagen production and connective tissue support.
  • We looked for evidence on: Fractures, Osteopenia, Osteoporosis, Wound healing, Joint health, Skin elasticity.
  • The closest evidence on file: Proline is rated "Insufficient Reliable Evidence To Rate" for Osteoporosis (Natural Medicines).
  • Also on file: Proline is rated "Insufficient Reliable Evidence To Rate" for Fractures, Wound healing, Osteopenia.

The evidence on L-Proline for athletic performance, bone health (osteoporosis, osteopenia, fractures), and wound healing is currently insufficient to rate. That means we don't yet have reliable data showing it works for these uses — not that it doesn't work, but that rigorous studies are lacking.

If you're considering it for any of these reasons, talk with your pharmacist or doctor about what the science actually supports right now.

The evidence, ingredient by ingredient Proline

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Proline from food is generally considered low-risk. But supplement safety at higher doses hasn't been well studied, so the caution here is that you shouldn't take extra amounts unless your doctor specifically recommends it.

There's not enough reliable data on supplemental doses during breastfeeding, so use caution if you're nursing — talk with your doctor or pharmacist first.

Side effects, ingredient by ingredient Proline

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for L-Proline in our data. That doesn't mean they can't happen, so if you're on any regular medications, it's worth a quick check with your pharmacist before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and some safety-information gaps remain.

If you're curious about L-Proline for joint support or collagen production and your doctor or pharmacist gives the okay, this product carries no documented drug interactions. Just know the evidence for specific health claims isn't established yet, and supplemental doses aren't as well-studied as whole-food sources.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 100% Pure L-Proline 2000 Milligrams, straight from the product label.

Brand NutraBio
Barcode (UPC) 649908234256
Net contents 120 V-Cap(s)
Market status On market
Date entered into DSLD Sep 25, 2015
DSLD ID 51017
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 100% Pure L-Proline 2000 Milligrams by NutraBio, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Vegetable Capsule(s)
Maximum serving Sizes:
3 Vegetable Capsule(s)
Servings per container
40
UPC/BARCODE
649908234256
IngredientAmount% DV
L-Proline2000 mg--

Other ingredients: Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

3 capsules ~ 1-2X daily Suggested Use: As a dietary supplement, take 3 vegetable capsules (2000mg) 1 to 2 times daily, or as directed by your physician.

Brand IP Statement(s)

Amino Therapy

NUTRABIO WITHOUT COMPROMISE SINCE 1996

General Statements

Made in a GMP & FDA inspected facility

100% Pure

Free Form Amino Acid

Pharmaceutical Grade HPLC Lab tested for potency

40 Servings 2000 milligrams

Made in USA

Manufactured in our GMP & FDA inspected facility

Vegetable Capsule

Formulation

No Fillers No Excipients No Additives

Free of Harmful Impurities

Vegetarian

Non-GMO Gluten Free BSE/TSE Free

Seals/Symbols

TRUE LABEL FULL LABEL DISCLOSURE

OU

FDA Statement of Identity

Dietary Supplement

Storage

Store in cool dry place

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

23425-002 B20147-004

Formula

Allergen Free

Precautions

Warning: Not intended for use by persons under the age of 18. Keep out of the reach of children.

If you are pregnant, breast feeding, have known medical conditions or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.

See for yourself

100% Pure L-Proline 2000 Milligrams by NutraBio label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in 100% Pure L-Proline 2000 Milligrams by NutraBio

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Vegetable Capsule(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.

L-Proline

No known
interactions
2000 mg per serving

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of...

L-Proline monograph & interactions

Other (inactive) ingredients: Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

100% Pure L-Proline 2000 Milligrams by NutraBio Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in 100% Pure L-Proline 2000 Milligrams. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for 100% Pure L-Proline 2000 Milligrams, from the product label.

NutraBio

See all NutraBio products
Name
NutraBio Labs, Inc.
Street Address
564 Lincoln Blvd.
City
Middlesex
State
NJ
ZipCode
08846
Phone Number
732-748-8606
Web Address
www.nutrabio.com
Pharmacist Counseling Corner

100% Pure L-Proline 2000 Milligrams by NutraBio: Common Questions

Does 100% Pure L-Proline 2000 Milligrams by NutraBio interact with any medications?
We do not currently list a known interaction for the mapped ingredients in 100% Pure L-Proline 2000 Milligrams. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
100% Pure L-Proline 2000 Milligrams contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does L-Proline interact with any of my medications?
No interactions are documented in our data for L-Proline. That said, absence of documented interactions isn't a guarantee none exist — run your specific medications through the checker on this page or ask your pharmacist to be sure.
Is it safe to take this while breastfeeding?
There isn't enough reliable data on supplemental L-Proline doses during breastfeeding to say either way. Talk with your doctor or pharmacist for personalized advice before you start.
Does it actually help with joint health or collagen?
The evidence on L-Proline for wound healing and bone health (osteoporosis, fractures, osteopenia) is currently insufficient to rate — meaning we don't yet have reliable studies showing it works. Your pharmacist can point you toward what the science does support.
What is L-Proline?
It's an amino acid — one of the building blocks your body uses to make collagen, a structural protein found in skin, joints, and connective tissue.
Is this product safe at the 2,000 mg dose?
L-Proline from food is generally low-risk, but supplement safety at higher doses hasn't been well studied. It's best not to take extra amounts unless your doctor advises you to — talk with your doctor or pharmacist about whether this dose is right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 100% Pure L-Proline 2000 Milligrams is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

100% Pure L-Proline 2000 Milligrams label
Go deeper

The Full Monographs Behind 100% Pure L-Proline 2000 Milligrams’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

100% Pure L-Proline 2000 Milligrams's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proline 4 references
  1. Jennings A, MacGregor A, Spector T, Cassidy A. Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: Evidence from discordant monozygotic twins. J Bone Miner Res. 2016;31(2):326-35. PubMed
  2. Gracia-Marco L, Bel-Serrat S, Cuenca-Garcia M, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49(6):1041-1052. PubMed
  3. Jamdar J, Rao B, Netke S, et al. Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline. J Altern Complement Med. 2004;10(6):915-6.
  4. Mehl AA, Damião AO, Viana SD, Andretta CP. Hard-to-heal wounds: a randomised trial of an oral proline-containing supplement to aid repair. J Wound Care 2021;30(1):26-31. PubMed

See these in context on the Proline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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