No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Proline 2,000 mg Ingredients & Drug Interactions

by Nutricost

Powder Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Proline 2,000 mg is a dietary supplement by Nutricost with 1 active ingredient. Its ingredients are commonly taken for joint and connective tissue support, skin health and wound healing, collagen production.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Proline 2,000 mg by Nutricost

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-proline, an amino acid your body uses to build and repair connective tissue like collagen. You're getting 2,000 mg per serving.

There are no inactive fillers or binders — it's proline powder only.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Proline product and its label doesn't state a use — see Proline's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we have doesn't establish that L-proline reliably works for athletic performance, bone strength (osteoporosis, fractures, or osteopenia), or wound healing. That's not to say it does nothing — it means the reliable studies simply aren't there yet in the data we hold.

The evidence, ingredient by ingredient Proline

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-proline from food sources is generally well tolerated. Supplement safety at higher doses hasn't been well studied, so it's wise to stick with the dose on the label unless your doctor tells you otherwise.

There isn't enough reliable data on supplemental doses during breastfeeding, so if you're nursing, talk it over with your doctor or pharmacist before taking extra amounts.

Side effects, ingredient by ingredient Proline

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the medications we checked. Still, run your specific prescriptions and over-the-counter drugs through the search tool on this page before you start, or ask your pharmacist.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.

L-Proline is an amino acid that plays a role in collagen, but we don't have solid evidence it works for the conditions it's often sold for. If you're thinking about adding it to support joints, bone, or recovery, it's worth discussing with your doctor or pharmacist to see if it makes sense for you.

Don't exceed the label dose without medical guidance.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Proline 2,000 mg, straight from the product label.

Brand Nutricost
Barcode (UPC) 810014671376
Net contents 8.8 oz; 250 Gram(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 270519
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Proline 2,000 mg by Nutricost, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
2 Gram(s)
Servings per container
125
UPC/BARCODE
810014671376
IngredientAmount% DV
L-Proline2000 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Use: As a dietary supplement, mix 1 scoop daily with 6-10 oz of water or as directed by your healthcare professional.

Precautions

Warning: For healthy individuals 18 years and older.

Consult a healthcare professional prior to use if you are pregnant or nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do not use if safety seal is broken or missing.

Storage

Notice: Store in a cool, dry place.

General Statements

Contents are sold by weight, not volume. Some settling may occur.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

2,000 mg per serving

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Quality Guaranteed Nutricost

Formulation

Third Party Tested

Non GMO Gluten Free Product

See for yourself

L-Proline 2,000 mg by Nutricost label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Proline 2,000 mg by Nutricost

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Servings per container125 Amounts shown are per serving.

L-Proline

No known
interactions
2000 mg per serving

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of...

L-Proline monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Proline 2,000 mg by Nutricost Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Proline 2,000 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Proline 2,000 mg, from the product label.

Nutricost

See all Nutricost products
Name
Nutricost
Street Address
351 E 1750 N
City
Vineyard
State
UT
ZipCode
84059
Phone Number
(866) 438-3694
Web Address
www.nutricost.com
Pharmacist Counseling Corner

L-Proline 2,000 mg by Nutricost: Common Questions

Does L-Proline 2,000 mg by Nutricost interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Proline 2,000 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Proline 2,000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does L-proline do in the body?
L-proline is an amino acid that your body uses to build and maintain collagen, the main protein in connective tissue, skin, joints, and bones. It's found naturally in protein-rich foods and in the supplements.
Will this help my joints or bones?
The research we have doesn't establish that L-proline reliably strengthens bones or improves joint health. The evidence for those uses is marked as insufficient, so we can't say yes or no based on what's in our data.
Is it safe to take while breastfeeding?
We don't have enough reliable data on supplemental doses of L-proline during breastfeeding. Talk it over with your doctor or pharmacist before taking it — they can advise based on your situation.
Can I take more than the label dose?
The safety of doses higher than what's recommended hasn't been well studied, so it's best to stick with the label dose unless your doctor advises differently.
Does this powder have fillers or other ingredients?
No — it's L-proline powder with no inactive fillers or binders added.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Proline 2,000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Proline 2,000 mg label
Go deeper

The Full Monographs Behind L-Proline 2,000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Proline 2,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proline 4 references
  1. Jennings A, MacGregor A, Spector T, Cassidy A. Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: Evidence from discordant monozygotic twins. J Bone Miner Res. 2016;31(2):326-35. PubMed
  2. Gracia-Marco L, Bel-Serrat S, Cuenca-Garcia M, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49(6):1041-1052. PubMed
  3. Jamdar J, Rao B, Netke S, et al. Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline. J Altern Complement Med. 2004;10(6):915-6.
  4. Mehl AA, Damião AO, Viana SD, Andretta CP. Hard-to-heal wounds: a randomised trial of an oral proline-containing supplement to aid repair. J Wound Care 2021;30(1):26-31. PubMed

See these in context on the Proline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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