No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pure L-Proline 500 Milligrams Ingredients & Drug Interactions

by Montiff

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

Pure L-Proline 500 Milligrams is a dietary supplement by Montiff with 1 active ingredient. Its ingredients are commonly taken for joint and connective tissue support, skin health and wound healing, collagen production.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pure L-Proline 500 Milligrams by Montiff

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-proline, an amino acid that your body uses to build and repair collagen — the main structural protein in skin, joints, bones, and connective tissue. The capsule itself is gelatin, and it also contains microcrystalline cellulose and magnesium stearate as inactive ingredients to help hold the capsule together and aid absorption.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Proline product and its label doesn't state a use — see Proline's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold rates L-proline's effectiveness as insufficient to make a reliable call for athletic performance, osteoporosis, fractures, wound healing, and osteopenia. That means the studies available aren't strong enough yet to say whether it works for those uses.

If you're thinking about taking it for one of these reasons, talk it over with your doctor — they can help you weigh what limited evidence exists alongside other options.

The evidence, ingredient by ingredient Proline

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-proline is generally well tolerated from food sources, but supplement safety at higher doses hasn't been well studied. The safety notes on file advise against taking extra amounts beyond what you'd get from food unless your doctor advises it.

There isn't enough reliable data on supplemental doses during breastfeeding, so caution is warranted if you're nursing — talk with your doctor or pharmacist about whether this product makes sense for you.

Side effects, ingredient by ingredient Proline

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for L-proline. Even so, check with your doctor or pharmacist before adding any new supplement to your routine, particularly if you take multiple medications or have underlying health conditions.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.

Pure L-Proline may appeal to you if you're interested in supporting collagen and connective tissue, though the evidence for specific health claims is not yet established. No interactions are documented for this ingredient, but it hasn't been as thoroughly studied at supplement doses as many other products.

Talk with your doctor or pharmacist before starting, especially if you're pregnant, breastfeeding, or have kidney or liver concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure L-Proline 500 Milligrams, straight from the product label.

Brand Montiff
Barcode (UPC) 683268104910
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2015
DSLD ID 42034
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure L-Proline 500 Milligrams by Montiff, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
100
UPC/BARCODE
683268104910
IngredientAmount% DV
L-Proline500 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

DO NOT REFRIGERATE.

STORE IN A COOL, DRY PLACE.

Precautions

KEEP OUT OF REACH OF CHILDREN.

General

Product#10491

Brand IP Statement(s)

(C) 1999 MONTIFF, INC. ALL RIGHTS RESERVED.

General Statements

MONTIFF - A DON TYSON COMPANY

Highest Quality Available

FDA Statement of Identity

Dietary Supplement

Formulation

Certified free of: Starch, corn, milk, wheat, yeast, sugar, eggs, salt, artificial colors, binders, flavors, preservatives and fish derivaties.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one (1) to three (3) capsules daily, or as recommended by a health care professional. To be used as a dietary supplement in a normal food program. It is recommended that this product be taken with vitamins and minerals.*

See for yourself

Pure L-Proline 500 Milligrams by Montiff label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pure L-Proline 500 Milligrams by Montiff

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

L-Proline

No known
interactions
500 mg per serving

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of...

L-Proline monograph & interactions

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure L-Proline 500 Milligrams by Montiff Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pure L-Proline 500 Milligrams. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pure L-Proline 500 Milligrams, from the product label.

Montiff

See all Montiff products
Name
Montiff, Inc.
City
LA County
State
CA
ZipCode
90404
Pharmacist Counseling Corner

Pure L-Proline 500 Milligrams by Montiff: Common Questions

Does Pure L-Proline 500 Milligrams by Montiff interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pure L-Proline 500 Milligrams. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pure L-Proline 500 Milligrams contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-proline and what does it do in my body?
L-proline is an amino acid — a building block of protein — that your body uses to make and repair collagen. Collagen is the main structural protein in your skin, joints, bones, and connective tissues. Your body can make some L-proline on its own, and you also get it from protein-rich foods like bone broth, gelatin, and meat.
Does this supplement actually work for bone health or wound healing?
The evidence we hold rates L-proline as having insufficient reliable data to say whether it works for osteoporosis, fractures, wound healing, or osteopenia. That means more research is needed before we can make a confident claim. If you're dealing with bone or wound concerns, your doctor can give you personalized advice.
Are there any side effects I should know about?
We have no adverse effects listed in our data for L-proline. That said, the safety of supplemental doses — amounts higher than you'd get from food — hasn't been well studied, so the caution is to avoid extra amounts unless your doctor advises otherwise.
Is it safe to take while breastfeeding?
There isn't enough reliable data on supplemental L-proline doses during breastfeeding to say either way. If you're nursing and interested in taking this product, talk with your doctor or pharmacist for personalized advice.
Will this interact with my medications?
No interactions are documented in our data for L-proline. Even so, it's always smart to check with your doctor or pharmacist before starting any new supplement, especially if you take multiple medications or have health conditions — they can review your full picture.
What else is in the capsule besides L-proline?
The capsule is made of gelatin, and it also contains microcrystalline cellulose and magnesium stearate — common inactive ingredients that help hold the capsule together and aid absorption.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure L-Proline 500 Milligrams is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure L-Proline 500 Milligrams label
Go deeper

The Full Monographs Behind Pure L-Proline 500 Milligrams’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pure L-Proline 500 Milligrams's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proline 4 references
  1. Jennings A, MacGregor A, Spector T, Cassidy A. Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: Evidence from discordant monozygotic twins. J Bone Miner Res. 2016;31(2):326-35. PubMed
  2. Gracia-Marco L, Bel-Serrat S, Cuenca-Garcia M, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49(6):1041-1052. PubMed
  3. Jamdar J, Rao B, Netke S, et al. Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline. J Altern Complement Med. 2004;10(6):915-6.
  4. Mehl AA, Damião AO, Viana SD, Andretta CP. Hard-to-heal wounds: a randomised trial of an oral proline-containing supplement to aid repair. J Wound Care 2021;30(1):26-31. PubMed

See these in context on the Proline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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