Pure L-Lysine 500 Milligrams Ingredients & Drug Interactions
by Montiff
What is this page for?
First and foremost: checking Pure L-Lysine 500 Milligrams against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pure L-Lysine 500 Milligrams is a dietary supplement by Montiff with 1 active ingredient. Its ingredients are commonly taken for cold sores (herpes labialis), genital herpes outbreaks, supporting protein and collagen formation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated minor. The ingredients most likely to interact are L-Lysine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Pure L-Lysine 500 Milligrams by Montiff
Ask about any prescription or over-the-counter medication and we check it for interactions with Pure L-Lysine 500 Milligrams by Montiff — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Pure L-Lysine 500 Milligrams by Montiff
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: L-lysine, an amino acid your body uses to build and repair proteins. L-lysine is found naturally in foods like chicken, cheese, and beans.
The capsule also holds inactive ingredients — gelatin, cellulose, magnesium stearate, and silicon dioxide — which help form and preserve the supplement.
Does it work?
Moderate evidence
L-lysine is possibly effective for cold sores (herpes labialis) when taken orally or applied topically, according to the data we hold. For other uses listed — child growth, pressure ulcers, and diabetic foot ulcers — the evidence isn't strong enough yet to say whether it works.
How safe is it?
Well-documented data
L-lysine is generally well tolerated at typical doses. High amounts may cause stomach upset like abdominal pain, diarrhea, or indigestion, and long-term safety at high doses hasn't been well studied.
There's one rare case report of oral lysine linked to kidney inflammation and chronic kidney failure, though this is uncommon. Lysine from food is safe in pregnancy, but supplement safety during pregnancy and breastfeeding isn't well studied — talk with your doctor or pharmacist before taking it if you're pregnant or nursing.
Meds to double-check
Minor interactions only
If you take a 5-HT4 agonist — a medication for digestive disorders — double-check with your pharmacist before adding this supplement, as L-lysine may reduce its effectiveness.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Only minor medication interactions are documented, and safety information is well characterized.
L-lysine is a reasonable option if you're looking for support with cold sores and you don't take 5-HT4 agonists for digestive issues. If you're pregnant, breastfeeding, or on any medications, check with your pharmacist first.
At high doses, watch for stomach upset.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pure L-Lysine 500 Milligrams, straight from the product label.
| Brand | Montiff |
|---|---|
| Barcode (UPC) | 683268104217 |
| Net contents | 200 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2024 |
| DSLD ID | 322093 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pure L-Lysine 500 Milligrams by Montiff, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Lysine | 500 mg | -- |
Other ingredients: Gelatin, Cellulose, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take one to three capsules daily, or as recommended by a health care professional. To be used as a dietary supplement in a normal food program. It is recommended that this product be taken with vitamins and minerals.
Formulation
Contains no starch, corn, milk, wheat, yeast, sugar, eggs, salt, artificial colors, binders, flavors, preservatives and fish derivatives. Soy and gluten free.
Highest Quality Available
Storage
Do not refrigerate. Keep in cool, dry place.
Precautions
Keep out of reach of children.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
Copyright 1999 Montiff, Inc. All Rights Reserved.
General Statements
Montiff A Don Tyson Company NDC: 65883-420-17
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pure L-Lysine 500 Milligrams by Montiff label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pure L-Lysine 500 Milligrams by Montiff
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container200 Amounts shown are per serving.
L-Lysine
Interacts with1 drug
Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...
L-Lysine monograph & interactionsOther (inactive) ingredients: Gelatin, Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Pure L-Lysine 500 Milligrams by Montiff Drug Interactions
HelloPharmacist Interaction Report
Pure L-Lysine 500 Milligrams by Montiff contains one ingredient, L-lysine, which has a documented interaction with 5-HT4 agonists — a class of medications used mainly for digestive disorders.
L-lysine may reduce how well these drugs work, based on animal research suggesting it acts as a partial blocker of the serotonin receptor these medications target.
Read the full breakdown — every affected drug type, severity by severity
Altogether, these interactions span 1 individual medication.
If you take a 5-HT4 agonist, run it through the checker below before starting this supplement so we can see your exact drug and advise you on timing or whether an adjustment makes sense.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Pure L-Lysine 500 Milligrams?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Pure L-Lysine 500 Milligrams interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in Pure L-Lysine 500 Milligrams interact with drugs. Each result below shows which ingredient is responsible. L-Lysine
TegaserodZelnorm
How Tegaserod interacts with Pure L-Lysine 500 Milligrams — through 1 ingredient. Tap an ingredient for the detail:
L-lysine5-ht4 Agonists Minor
Interaction Summary
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Read the full L-lysine + Tegaserod interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Pure L-Lysine 500 Milligrams with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Lysine
5-Ht4 Agonists
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.
Brand information
Manufacturer and brand details for Pure L-Lysine 500 Milligrams, from the product label.
Montiff
See all Montiff products- Name
- Montiff, Inc.
- Street Address
- 3205 Santa Monica Blvd.
- City
- Santa Monica
- State
- CA
- ZipCode
- 90404
Pure L-Lysine 500 Milligrams by Montiff: Common Questions
Does Pure L-Lysine 500 Milligrams by Montiff interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does L-lysine actually help with cold sores?
What side effects might I get from L-lysine?
Is L-lysine safe to take during pregnancy?
Is L-lysine safe while breastfeeding?
What exactly is L-lysine and why is it in supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Pure L-Lysine 500 Milligrams is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pure L-Lysine 500 Milligrams’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Pure L-Lysine 500 Milligrams's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lysine 7 references
- Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
- McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
- DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
- Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
- Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
- Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
- Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC