No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Proline Ingredients & Drug Interactions

by Earthborn Elements

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Proline is a dietary supplement by Earthborn Elements with 1 active ingredient. Its ingredients are commonly taken for joint and connective tissue support, skin health and wound healing, collagen production.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Proline by Earthborn Elements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-Proline, an amino acid your body uses to build and repair connective tissue, including collagen in skin, joints, and bones. The capsule itself is made of gelatin, an inert ingredient used to hold the powder.

L-Proline is found naturally in foods like bone broth, meat, and dairy, and your body can also make small amounts on its own.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Proline product and its label doesn't state a use — see Proline's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for L-Proline's effectiveness isn't well established yet. The data we hold rates it as having insufficient reliable evidence to support claims about athletic performance, bone health (osteoporosis, osteopenia, fractures), and wound healing.

That doesn't mean it doesn't work — it means quality studies haven't proven it one way or the other.

The evidence, ingredient by ingredient Proline

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Proline from food sources is generally well tolerated. Supplement safety at higher doses, though, hasn't been studied much, so we don't know how much extra is actually safe.

The safety data during breastfeeding is also limited — there isn't enough reliable information to know either way. No adverse effects (side effects) are documented in the data we hold.

If you're pregnant or breastfeeding, talk with your doctor or pharmacist before starting this supplement, since personalized advice matters here.

Side effects, ingredient by ingredient Proline

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for L-Proline in our data.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.

L-Proline is a basic amino acid with no documented drug interactions, so it won't clash with your medications. But the evidence that it actually works for joints, bone health, or healing isn't strong yet.

If you're curious about it, there's no safety red flag — just know you're taking it on limited proof of benefit.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Proline, straight from the product label.

Brand Earthborn Elements
Net contents 200 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 319616
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Proline by Earthborn Elements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
200
IngredientAmount% DV
L-Proline410 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 capsule, preferably with meals. Take with at least 8 oz of liquid.

Precautions

If pregnant, nursing, or taking medications, consult your physician.

General Statements

Questions? Concerns? Scan this code with your phone's camera to chat with us online and get 20% coupon for your next Amazon Earthborn Elements order!

FDA Statement of Identity

Dietary Supplement

See for yourself

L-Proline by Earthborn Elements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Proline by Earthborn Elements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container200 Amounts shown are per serving.

L-Proline

No known
interactions
410 mg per serving

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of...

L-Proline monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Proline by Earthborn Elements Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Proline. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Proline, from the product label.

Earthborn Elements

See all Earthborn Elements products
Name
Earthborn Elements
Street Address
9450 SW Gemini Dr #49936
City
Beaverton
State
Oregon
ZipCode
97008
Web Address
Earthbornelements.com
Pharmacist Counseling Corner

L-Proline by Earthborn Elements: Common Questions

Does L-Proline by Earthborn Elements interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Proline. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Proline contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will L-Proline interact with my blood pressure or heart medications?
No interactions are documented between L-Proline and any medications in our data. Still, run your exact drugs through the checker on this page to be sure.
Is L-Proline safe to take while breastfeeding?
There isn't enough reliable data to know whether supplemental doses are safe while breastfeeding. Talk with your doctor or pharmacist before starting — they can give you personalized advice.
Does L-Proline actually help joints or skin?
The evidence isn't strong enough yet to say for sure. The data rates it as having insufficient reliable evidence for joint health, bone health, and wound healing.
What does L-Proline do in my body?
L-Proline is an amino acid your body uses to make and repair collagen, the protein that gives structure to skin, tendons, ligaments, and bones. You get small amounts from foods like bone broth and meat.
Are there any side effects?
No adverse effects are documented in the data we hold. L-Proline from food is generally well tolerated, though supplement safety at higher doses hasn't been well studied.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Proline is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Proline label
Go deeper

The Full Monographs Behind L-Proline’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Proline's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proline 4 references
  1. Jennings A, MacGregor A, Spector T, Cassidy A. Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: Evidence from discordant monozygotic twins. J Bone Miner Res. 2016;31(2):326-35. PubMed
  2. Gracia-Marco L, Bel-Serrat S, Cuenca-Garcia M, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49(6):1041-1052. PubMed
  3. Jamdar J, Rao B, Netke S, et al. Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline. J Altern Complement Med. 2004;10(6):915-6.
  4. Mehl AA, Damião AO, Viana SD, Andretta CP. Hard-to-heal wounds: a randomised trial of an oral proline-containing supplement to aid repair. J Wound Care 2021;30(1):26-31. PubMed

See these in context on the Proline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring