L-Tryptophan Peptide Ingredients & Drug Interactions
What is this page for?
First and foremost: checking L-Tryptophan Peptide against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Tryptophan Peptide is a dietary supplement by Jarrow Formulas with 1 active ingredient. Its ingredients are commonly taken for sleep problems, low mood and depression, anxiety.Based on those ingredients, 394 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are L-Tryptophan Peptides. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against L-Tryptophan Peptide by Jarrow Formulas
Ask about any prescription or over-the-counter medication and we check it for interactions with L-Tryptophan Peptide by Jarrow Formulas — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of L-Tryptophan Peptide by Jarrow Formulas
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains a single active ingredient: L-tryptophan peptides, which are chains of the amino acid L-tryptophan. L-tryptophan is an essential amino acid your body uses to make serotonin, a chemical messenger involved in mood, sleep, and other functions.
The product also contains several inactive ingredients — calcium phosphate, cellulose, stearic acid, silicon dioxide, magnesium stearate, and a food-grade coating — which serve as fillers and binders to form the tablet.
Does it work?
Not established
The evidence on L-tryptophan for the conditions it's marketed for is limited. For depression, the data we hold rates it as possibly ineffective.
For anxiety, athletic performance, teeth grinding (bruxism), and premenstrual dysphoric disorder (PMDD), there isn't enough reliable evidence to establish whether it works. If you're considering this product for any of these uses, talk it over with your doctor — they can help you weigh the limited evidence against other options.
How safe is it?
Well-documented data
L-tryptophan is generally well tolerated when taken by mouth. Common side effects include belching, diarrhea, drowsiness, dry mouth, flatulence, headache, heartburn, lightheadedness, nausea, stomach pain, blurred vision, and vomiting.
A serious rare concern is eosinophilia-myalgia syndrome (EMS), a neurological disorder — however, nearly all cases documented in the U.S. in the late 1980s were traced to a contaminated batch from a single Japanese manufacturer, and modern products are produced under stricter controls. The safety data advises against L-tryptophan during pregnancy and while breastfeeding.
Meds to double-check
Major interaction found
Before taking this product, check with your doctor or pharmacist if you take any CNS depressants — sedatives, sleep aids, opioids, alcohol, or other drugs that cause drowsiness — because L-tryptophan may boost their sedative effect. Also double-check if you're on serotonergic medications like antidepressants or migraine drugs, as combining them with L-tryptophan might increase serotonin-related side effects.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
L-Tryptophan Peptide is an option if you're exploring amino acid support for mood or sleep, but the evidence for depression is weak and evidence for other uses is lacking. The biggest concern is mixing it with sedating drugs or serotonin-based medications — if you take any of those, check first with your doctor or pharmacist before adding this.
Avoid it if you're pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Tryptophan Peptide, straight from the product label.
| Brand | Jarrow Formulas |
|---|---|
| Barcode (UPC) | 790011150671 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Dec 22, 2019 |
| DSLD ID | 212250 |
| Product type | Amino Acid/protein |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Tryptophan Peptide by Jarrow Formulas, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Tryptophan Peptides | 1350 mg | -- |
| L-Tryptophan | 500 mg | -- |
Other ingredients: Calcium Phosphate, Cellulose, Stearic Acid, Silicon Dioxide, Magnesium Stearate, food-grade Coating
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Usage: Take 2 tablets on an empty stomach 30 minutes before sleep with water or fruit juice or as directed by your qualified healthcare professional.
Precautions
Warning: Do not drive or operate machinery immediately following use of this product; Do not take this product if you are on any medications (especially antidepressents [e.g., SSRIs (selective serotonin reuptake inhibitors)]).
Warning: Do not drive or operate machinery immediately following use of this product; Do not take this product if you are on any medications (especially antidepressents [e.g., SSRIs (selective serotonin reuptake inhibitors)]). If you are pregnant breastfeeding, trying to conceive, under the age of 18, or have a medical condition, consult your qualified healthcare professional before using this product.
If you are pregnant breastfeeding, trying to conceive, under the age of 18, or have a medical condition, consult your qualified healthcare professional before using this product.
Keep out of the reach of children.
Contains: Milk.
No wheat, gluten, soybeans, egg, fish/shellfish, or peanuts/tree nuts.
Formulation
Jarrow Formulas L-Tryptophan Peptide uses PepForm technology.
For relaxation, positive mood & sleep
Veggie
No wheat, gluten, soybeans, egg, fish/shellfish, or peanuts/tree nuts.
Suitable for vegetarians.
Formula
L-tryptophan is an essential amino acid and must be obtained from food or supplements. L-tryptophan is metabolized to serotonin (5-hydroxytryptamine) and melatonin, which is important for relaxation, restful sleep and positive mood.
TRP PepForm Tryptophan Peptides
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
PepForm is a trademark of Glanbia plc.
2018 Jarrow Formulas
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Tryptophan Peptide by Jarrow Formulas label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Tryptophan Peptide by Jarrow Formulas
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.
L-Tryptophan Peptides
Interacts with394 drugs
L-tryptophan is an essential amino acid the body uses to make serotonin and melatonin, and people take it to support sleep and mood. The evidence for...
L-Tryptophan Peptides monograph & interactionsOther (inactive) ingredients: Calcium Phosphate, Cellulose, Stearic Acid, Silicon Dioxide, Magnesium Stearate, Food-grade Coating. These complete the product’s ingredient list but are not active constituents.
L-Tryptophan Peptide by Jarrow Formulas Drug Interactions
HelloPharmacist Interaction Report
L-Tryptophan Peptide by Jarrow Formulas interacts with two major drug categories through its L-tryptophan content.
The most serious concern is with CNS depressants (sedatives, sleep aids, opioids, alcohol, and similar drugs that slow the central nervous system) — combining them with L-tryptophan may cause additive sedative effects and increase drowsiness and fatigue.
Read the full breakdown — every affected drug type, severity by severity
L-tryptophan also has documented moderate-severity interactions with serotonergic drugs — antidepressants, migraine medications, and similar drugs that work through serotonin. Because L-tryptophan is a building block for serotonin, combining it with these medications might increase serotonergic side effects, including the rare but serious condition serotonin syndrome.
Altogether, these interactions span 394 individual medications. Before you start this product, check your exact medications with the tool on this page or ask your doctor or pharmacist whether any of your prescriptions or over-the-counter drugs fall into these categories.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against L-Tryptophan Peptide?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in L-Tryptophan Peptide interact with 394 drugs. Click any drug to see the details.
1 of the 1 ingredient in L-Tryptophan Peptide interact with drugs. Each result below shows which ingredient is responsible. L-Tryptophan Peptides
Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAlmotriptanAlmogran, Axert
How Almotriptan interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Almotriptan interactionAlosetronLotronex
How Alosetron interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Alosetron interactionAmoxapineAsendin
How Amoxapine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Amoxapine interactionAmphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine SulfateAdderall, Adderall XR
How Amphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Amphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAtropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, PhenylAtrosept
How Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl interactionAtropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl SalicylateUrinary Antiseptic 2, Urised
How Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl Salicylate interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl Salicylate interactionAtropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, ScopolamineAtrohist Plus, Pro Tuss, Ru-tuss, Stahist
How Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interactionBelladonna Alkaloids, Chlorpheniramine, Phenylephrine, PhenylpropanolamineRespa ARM
How Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interactionBenzocaine, DextromethorphanTetra-Formula
How Benzocaine, Dextromethorphan interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Benzocaine, Dextromethorphan interactionBrexpiprazoleRexulti
How Brexpiprazole interacts with L-Tryptophan Peptide — through 1 ingredient. Tap an ingredient for the detail:
L-tryptophanSerotonergic Drugs Moderate
Interaction Summary
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
Read the full L-tryptophan + Brexpiprazole interactionEach ingredient & the kinds of drugs it affects
For each ingredient in L-Tryptophan Peptide with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Tryptophan Peptides
Cns Depressants
Theoretically, concomitant use of L-tryptophan with CNS depressants might cause additive sedative effects.
Clinical research shows that L-tryptophan can cause fatigue and drowsiness.
Serotonergic Drugs
Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.
L-tryptophan is a precursor to serotonin. Theoretically, combining serotonergic drugs with L-tryptophan might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders.
Brand information
Manufacturer and brand details for L-Tryptophan Peptide, from the product label.
Jarrow Formulas
See all Jarrow Formulas products- Name
- Jarrow Formulas Superior Nutrition and Formulation
- Street Address
- P.O. Box 35994
- City
- Los Angeles
- State
- CA
- ZipCode
- 90035-4317
- Web Address
- www.Jarrow.com
L-Tryptophan Peptide by Jarrow Formulas: Common Questions
Does L-Tryptophan Peptide by Jarrow Formulas interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What are L-tryptophan peptides, and why are they in this product?
Does this really help with depression or anxiety?
What are the most common side effects?
I've heard about a contamination scare with L-tryptophan. Should I be worried?
Can I take this while pregnant or breastfeeding?
Can I take this with my sleep medication or antidepressant?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Tryptophan Peptide is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Tryptophan Peptide’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
L-Tryptophan Peptide's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 18 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
L-tryptophan 18 references
- Messiha FS. Fluoxetine: adverse effects and drug-drug interactions. J Toxicol Clin Toxicol 1993;31:603-30. PubMed
- Devoe LD, Castillo RA, Searle NS. Maternal dietary substrates and human fetal biophysical activity. The effects of tryptophan and glucose on fetal breathing movements. Am J Obstet Gynecol 1986;155:135-9. DOI
- Lieberman HR, Corkin S, Spring BJ. The effects of dietary neurotransmitter precursors on human behavior. Am J Clin Nutr 1985;42:366-70. PubMed
- U. S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, Office of Nutritional Products, Labeling, and Dietary Supplements. Information Paper on L-Tryptophan and 5-hydroxy-L-tryptophan, February 2001.
- Sullivan EA, Kamb ML, Jones JL, et al. The natural history of eosinophilia-myalgia syndrome in a tryptophan-exposed cohort in South Carolina. Arch Intern Med 1996;156:973-9. DOI
- Philen RM, Hill RH, Flanders WD, et al. Tryptophan contaminants associated with eosinophilia-myalgia syndrome. Am J Epidemiol 1993;138:154-9. PubMed
- Bohme A, Wolter M, Hoelzer D. L-tryptophan-related eosinophilia-myalgia syndrome possibly associated with a chronic B-lymphocytic leukemia. Ann Hematol 1998;77:235-8. PubMed
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