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Dietary supplement

L-Tyrosine 500 mg Ingredients & Drug Interactions

by Jarrow Formulas

Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

L-Tyrosine 500 mg is a dietary supplement by Jarrow Formulas with 1 active ingredient. Its ingredients are commonly taken for mental focus and alertness, coping with stress, fatigue and sleep loss.Based on those ingredients, 21 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Tyrosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of L-Tyrosine 500 mg by Jarrow Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-tyrosine, an amino acid your body uses to make neurotransmitters and thyroid hormone. The capsule also holds inactive ingredients — bovine gelatin, microcrystalline cellulose, magnesium stearate, and silicon dioxide — that serve as the capsule shell and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: brain support and neurotransmitter production.
  • We looked for evidence on: Attention deficit-hyperactivity disorder (ADHD), Cognitive function, Depression, Fatigue, Memory, Narcolepsy — and 4 related terms.
  • The strongest evidence on file: Tyrosine is rated "Possibly Effective" for Cognitive function (Natural Medicines).
  • Also on file: Tyrosine is rated "Possibly Effective" for Memory.
  • Also on file: Tyrosine is rated "Insufficient Reliable Evidence To Rate" for Attention deficit-hyperactivity disorder (ADHD), Depression, Fatigue, Sleep deprivation, and more.

L-tyrosine is effective for phenylketonuria (PKU), a genetic condition. For cognitive function and memory, the evidence suggests it may help, though the data isn't conclusive.

For athletic performance, current evidence suggests it doesn't work. For alcohol use disorder and dementia, we don't have enough reliable evidence yet to say whether it's effective.

The evidence, ingredient by ingredient Tyrosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-tyrosine is generally well tolerated in healthy adults, but there isn't enough safety data to recommend regular use without talking to your doctor first. The most common side effects from oral use are fatigue, headache, heartburn, and nausea — these tend to show up at higher doses.

No serious side effects have been documented, though we don't have a complete safety evaluation. During pregnancy, there isn't enough data; during breastfeeding, caution is advised — talk with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Tyrosine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tyrosine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: Parkinson's medications.
  • For scale: 21 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take levodopa (Parkinson's medication) or thyroid hormones. Both have documented Moderate-severity interactions with L-tyrosine.

If you do take one of these, they can help you with timing and dose to minimize the risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have PKU, L-tyrosine is established as an effective treatment. If you're interested in it for memory or thinking, the science is still preliminary.

Anyone taking levodopa or thyroid medication should check with their doctor or pharmacist first, and if you're pregnant or breastfeeding, run this by your healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Tyrosine 500 mg, straight from the product label.

Brand Jarrow Formulas
Barcode (UPC) 790011150015
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 307643
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Tyrosine 500 mg by Jarrow Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
790011150015
IngredientAmount% DV
L-Tyrosine500 mg--

Other ingredients: Bovine Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Adults take 1 capsule once a day on an empty stomach, immediately after arising in the morning, preferably with juice or as directed by your qualified healthcare professional.

Formula

Jarrow Formulas L-Tyrosine is pure crystalline L-Tyrosine. L-Tyrosine, a constituent of dietary protein, is a precursor to the catecholamine neurotransmitters norepinephrine, epinephrine and dopamine, the levels of which can be affected by the amount of tyrosine consumed.

Precautions

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication (especially MAO inhibitors) or have a medical condition (especially bipolar or a history of malignant melanoma); if adverse reactions occur, discontinue use.

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication (especially MAO inhibitors) or have a medical condition (especially bipolar or a history of malignant melanoma); if adverse reactions occur, discontinue use. Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Brain support Supports production of neurotransmitters

Non-GMO Gluten free

No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Copyright 2022 Jarrow Formulas

General Statements

Amino acid

See for yourself

L-Tyrosine 500 mg by Jarrow Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Tyrosine 500 mg by Jarrow Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

L-Tyrosine

Interacts with
21 drugs
500 mg per serving

L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performan...

L-Tyrosine monograph & interactions

Other (inactive) ingredients: Bovine Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Tyrosine 500 mg by Jarrow Formulas Drug Interactions

Want to check YOUR meds against L-Tyrosine 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
21Drugs
21 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Tyrosine 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Tyrosine2 drug types · 21 drugs

Levodopa

Theoretically, tyrosine might decrease the effectiveness of levodopa.
Tyrosine and levodopa compete for absorption in the proximal duodenum by the large neutral amino acid (LNAA) transport system. Advise patients to separate doses of tyrosine and levodopa by at least 2 hours.

Likelihood Probable Evidence D
Thyroid Hormone

Theoretically, tyrosine might have additive effects with thyroid hormone medications.
Tyrosine is a precursor to thyroxine and might increase levels of thyroid hormones.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for L-Tyrosine 500 mg, from the product label.

Jarrow Formulas

See all Jarrow Formulas products
Name
Jarrow Formulas, Inc.
City
Sherman Oaks
State
CA
ZipCode
91403
Phone Number
1-866-459-4154
Pharmacist Counseling Corner

L-Tyrosine 500 mg by Jarrow Formulas: Common Questions

Does L-Tyrosine 500 mg by Jarrow Formulas interact with any medications?
Yes. Based on its ingredients, L-Tyrosine 500 mg has a known interaction with 21 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Tyrosine 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-tyrosine used for?
L-tyrosine is an amino acid your body needs to make neurotransmitters (brain chemicals) and thyroid hormone. It's proven effective for PKU, a genetic condition, and some evidence suggests it may support cognitive function and memory, though that data isn't conclusive.
What are the most common side effects?
The most common side effects from L-tyrosine are fatigue, headache, heartburn, and nausea. These tend to happen at higher doses, and lowering your dose can help reduce them. No serious side effects have been documented.
Can I take this while pregnant or breastfeeding?
During pregnancy, there isn't enough safety data to say either way. During breastfeeding, caution is advised. Talk with your doctor or pharmacist — they can weigh the pros and cons for your situation and give you personalized advice.
Does L-tyrosine help with athletic performance?
No. Current evidence suggests L-tyrosine doesn't improve athletic performance.
Is this safe to take long-term?
L-tyrosine is generally well tolerated, but there isn't enough long-term safety data to recommend regular use on your own. Before taking it regularly, talk with your healthcare provider to make sure it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Tyrosine 500 mg label
Go deeper

The Full Monographs Behind L-Tyrosine 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Tyrosine 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tyrosine 4 references
  1. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
  2. DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
  3. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
  4. van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed

See these in context on the Tyrosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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