Liposomal NAD+ Eternal Ingredients & Drug Interactions
by Codeage
What is this page for?
First and foremost: checking Liposomal NAD+ Eternal against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Liposomal NAD+ Eternal is a dietary supplement by Codeage with 2 active ingredients. Its ingredients are commonly taken for high homocysteine levels, liver health (fatty liver), exercise performance and strength.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Liposomal NAD+ Eternal by Codeage
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 2 active ingredients. Betaine anhydrous is an amino acid derivative that your body uses to help regulate a compound called homocysteine and support cellular processes.
Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme found naturally in your cells that's involved in energy production and cellular metabolism. The remaining ingredients are inactive — methylcellulose, microcrystalline cellulose, and sunflower lecithin — which serve as capsule materials and binders.
Does it work?
Strong evidence
Betaine anhydrous is effective for homocystinuria (a rare genetic condition affecting homocysteine metabolism) and possibly effective for hyperhomocysteinemia (elevated homocysteine in the blood). For other uses listed — nonalcoholic steatohepatitis (NASH), colorectal adenoma prevention, depression, and GERD — the evidence isn't strong enough to rate it either way.
We don't hold effectiveness data in our system for NAD+ itself, so we can't speak to what the research shows on that ingredient.
How safe is it?
Well-documented data
Betaine anhydrous is generally well tolerated at studied doses, though some people experience body odor, nausea, vomiting, diarrhea, GI distress, elevated cholesterol, or other mild digestive effects. Serious side effects are rare but can include brain swelling (cerebral edema).
There isn't enough reliable safety data overall, so talk with a doctor before starting this supplement. Safety while breastfeeding isn't well established, so caution is advised if you're nursing.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. Even so, if you take any prescription medications, use the interaction checker on this page with your exact drug names before starting.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.
Betaine anhydrous has solid evidence for homocystinuria and some support for elevated homocysteine. If you're pregnant, breastfeeding, or taking any medications, check with your pharmacist or doctor first — especially since we couldn't verify safety data for NAD+ or rule out interactions completely.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Liposomal NAD+ Eternal, straight from the product label.
| Brand | Codeage |
|---|---|
| Barcode (UPC) | 850049609029 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2025 |
| DSLD ID | 328898 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Liposomal NAD+ Eternal by Codeage, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Betaine Anhydrous | 102.5 mg | -- |
| Nicotinamide Adenine Dinucleotide | 500 mg | -- |
Other ingredients: Methylcellulose, Microcrystalline Cellulose, Sunflower Lecithin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Bioavailable NAD + Trimethylglycine Essential Phospholipids
Nicotinamide Adenine Dinucleotide Trimethylglycine
Formulation
Vegan
Non-GMO Soy-free Dairy-free Gluten-free
cGMP Certified Manufacturing
Enhanced absorption
General Statements
Ln 22.2302.05L Feel Different
HDPE BPS-Free Please recycle Bottle & Cap Please take off the label Scan for info
Questions? Codeage.com
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested use: Adults take 2 capsules daily, or as recommended by your healthcare practitioner, with 8 ounces of water or your favorite beverage. May be taken with or without food.
Brand IP Statement(s)
Copyright Codeage LLC. All rights reserved.
Precautions
Caution: Do not exceed recommended dose. Discontinue use two weeks prior to surgery.
Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children and pets.
Please use caution if you have allergies or sensitivities to any of the listed ingredients. This product is manufactured in a facility that processes fish and tree nuts.
Do not use if product has been opened or tampered with in any way. Keep out of reach of children and pets.
Keep out of reach of children and pets.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Liposomal NAD+ Eternal by Codeage label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Liposomal NAD+ Eternal by Codeage
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Betaine Anhydrous
No knowninteractions
Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and a...
Betaine Anhydrous monograph & interactionsNicotinamide Adenine Dinucleotide
Other (inactive) ingredients: Methylcellulose, Microcrystalline Cellulose, Sunflower Lecithin. These complete the product’s ingredient list but are not active constituents.
Liposomal NAD+ Eternal by Codeage Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Liposomal NAD+ Eternal. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Liposomal NAD+ Eternal, from the product label.
Codeage
See all Codeage products- Name
- Codeage LLC
- Street Address
- 5628 Washington Blvd
- City
- Los Angeles
- State
- CA
- ZipCode
- 90016
- Web Address
- www.codeage.com
Liposomal NAD+ Eternal by Codeage: Common Questions
Does Liposomal NAD+ Eternal by Codeage interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does betaine anhydrous actually do?
Is it safe to take if I'm pregnant?
Can it cause stomach problems?
Is there enough data to know NAD+ actually works?
What are the inactive ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Liposomal NAD+ Eternal is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Liposomal NAD+ Eternal’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Liposomal NAD+ Eternal's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Betaine Anhydrous 11 references
- Cystadane (betaine anhydrous for oral solution) Package insert. Orphan Medical, Inc. Minnetonka, MN. November 2005.
- Abdelmalek MF, Angulo P, Jorgensen RA, et al. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 2001;96:2711-7.. PubMed
- Schwab U, Torronen A, Toppinen L, et al. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr 2002;76:961-7. PubMed
- McGregor DO, Dellow WJ, Robson RA, et al. Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure. Kidney Int 2002;61:1040-6. PubMed
- Olthof MR, van Vliet T, Verhoef P, et al. Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans. PloS Med 2005;2:e135. PubMed
- Knopman, D. and Patterson, M. An open-label, 24-week pilot study of the methyl donor betaine in Alzheimer disease patients. Alzheimer Dis.Assoc.Disord. 2001;15(3):162-165. PubMed
- Moat, S. J., Madhavan, A., Taylor, S. Y., Payne, N., Allen, R. H., Stabler, S. P., Goodfellow, J., McDowell, I. F., Lewis, M. J., and Lang, D. High- but not low-dose folic acid improves endothelial function in coronary artery disease. Eur J Clin Invest 2 PubMed
- Abdelmalek, M. F., Sanderson, S. O., Angulo, P., Soldevila-Pico, C., Liu, C., Peter, J., Keach, J., Cave, M., Chen, T., McClain, C. J., and Lindor, K. D. Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial. Hepa PubMed
- Ashtary-Larky D, Bagheri R, Ghanavati M, et al. Effects of betaine supplementation on cardiovascular markers: a systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2021 Mar 25:1-18. PubMed
- Zawieja EE, Zawieja B, Chmurzynska A. Betaine supplementation moderately increases total cholesterol levels: a systematic review and meta-analysis. J Diet Suppl. 2021;18(1):105-117. PubMed
- Imbard A, Toumazi A, Magréault S, et al. Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial. Orphanet J Rare Dis 2022;17(1):417. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC