Major interaction on record — check this product against your medications before combining. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Liquid D3 & MK-7 Ingredients & Drug Interactions

by Protocol For Life Balance

Liquid Category: Vitamin
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Liquid D3 & MK-7 is a dietary supplement by Protocol For Life Balance with 2 active ingredients. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Liquid D3 & MK-7 by Protocol For Life Balance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 2 active ingredients: vitamin D3 and vitamin K2 (MK-7). It's a liquid formula, so you get both fat-soluble vitamins in one bottle.

The other ingredients are medium-chain triglyceride oil and peppermint oil, which help deliver and flavor the liquid.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Bone and cardiovascular support.
  • We looked for evidence on: Cardiovascular disease (CVD), Osteoporosis, Wound healing, Hemorrhagic disease, Hypoprothrombinemia, Vitamin K-dependent clotting factors deficiency (VKCFD) — and 4 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Hemorrhagic disease (Natural Medicines).
  • Also on file: Vitamin K is rated "Effective" for Hypoprothrombinemia, Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.

Vitamin K2 is effective for treating vitamin K deficiency and supporting blood clotting factors your body needs. It's also possibly effective for bone health and osteoporosis — the evidence suggests it may help, though more research is still being done.

We don't have effectiveness data on file for vitamin D3 in this product.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin K2 is generally well tolerated when taken by mouth in the amounts you'd find in food and most supplements. The most common side effects are mild — nausea, stomach upset, and diarrhea in some people.

It's safe during pregnancy and breastfeeding. That said, if you're thinking about taking a vitamin K supplement, check with your doctor first, since it can interact with certain medications like blood thinners.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or any blood thinner, this is a must-check before you start — vitamin K2 can reduce how well your medication works. We couldn't check vitamin D3 for interactions, so run your full medication list through the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This is a solid choice if you're looking to support your vitamin D and K2 levels and you don't take blood thinners. If you're on warfarin or any other anticoagulant, talk to your pharmacist before you start — this product could interfere with how your medication works.

Everyone else should check their medications against our tool below.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Liquid D3 & MK-7, straight from the product label.

Brand Protocol For Life Balance
Barcode (UPC) 707359103795
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 337819
Product type Vitamin
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Halal, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Liquid D3 & MK-7 by Protocol For Life Balance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.18 mL
Maximum serving Sizes:
0.18 mL
Servings per container
163
UPC/BARCODE
707359103795
IngredientAmount% DV
Vitamin D362.5 mcg313%
Vitamin K2100 mcg--

Other ingredients: Medium Chain Triglyceride Oil, Peppermint Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Shake well. Take 5 drops daily, or as directed by your healthcare practitioner. Take directly or add to a beverage. Best when taken with a fat-containing meal.

Precautions

Caution/Interactions: For adults only. Not for use in infants or children.

Vitamin D should be used cautiously by those taking cardiac glycosides and anyone with hypercalcemia. Vitamin D supplements may interact with atorvastatin and thiazide diuretics. Vitamin K is contraindicated with warfarin or other anti-coagulant medications. If you are taking any of these prescription medications, consult your healthcare practitioner before using this product.

Keep out of reach of children.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

2,500 IU vitamin D3 & 100 mcg vitamin K2 per 5 drops MenaQ7 Vitamin K2 as MK-7

Crescent H (Halal)

Formulation

Bone & cardiovascular support

Non-GMO

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients.

FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

MenaQ7 is a registered trademark of NattoPharma ASA, Norway. Patents granted and pending.

Seals/Symbols

Crescent H (Halal)

See for yourself

Liquid D3 & MK-7 by Protocol For Life Balance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Liquid D3 & MK-7 by Protocol For Life Balance

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.18 mL Dosage formLiquid Servings per container163 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin D3

62.5 mcg per serving Form: Cholecalciferol

Vitamin K2

Interacts with
2 drugs
100 mcg per serving Form: Mena Q7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Other (inactive) ingredients: Medium Chain Triglyceride Oil, Peppermint Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Liquid D3 & MK-7 by Protocol For Life Balance Drug Interactions

Want to check YOUR meds against Liquid D3 & MK-7?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Liquid D3 & MK-7 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
The maker

Brand information

Manufacturer and brand details for Liquid D3 & MK-7, from the product label.

Protocol For Life Balance

See all Protocol For Life Balance products
Name
Protocol For Life Balance
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
protocolforlife.com
Pharmacist Counseling Corner

Liquid D3 & MK-7 by Protocol For Life Balance: Common Questions

Does Liquid D3 & MK-7 by Protocol For Life Balance interact with any medications?
Yes. Based on its ingredients, Liquid D3 & MK-7 has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Liquid D3 & MK-7 contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
Not without talking to your doctor or pharmacist first. Vitamin K2 in this product can block warfarin's blood-thinning effect, which is dangerous. Your provider can tell you whether it's safe for you or if you need a different approach to vitamin D and K.
Will this help my bones?
Vitamin K2 may help with bone health and osteoporosis — the evidence suggests it possibly works — but it's not proven yet. Talk to your doctor about whether this product fits your bone-health plan.
Is it safe during pregnancy?
Yes. Vitamin K2 is rated likely safe in pregnancy and breastfeeding. That said, any supplement decision in pregnancy or while nursing should be made with your doctor.
What side effects might I notice?
Most people tolerate it well. If you do notice something, nausea, stomach upset, or diarrhea are the most common — usually mild. Stop and talk to your pharmacist if they bother you.
Why is this a liquid instead of a capsule?
Both vitamin D3 and K2 are fat-soluble, meaning they work best when absorbed with fat. The liquid form with medium-chain triglyceride oil helps your body absorb them better than a capsule might.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Liquid D3 & MK-7 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Liquid D3 & MK-7 label
Sources

Sources & How We Checked

Liquid D3 & MK-7's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring