LJ-100 200 mg Ingredients & Drug Interactions
by SuperSmart
What is this page for?
First and foremost: checking LJ-100 200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
LJ-100 200 mg is a dietary supplement by SuperSmart with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are LJ-100. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against LJ-100 200 mg by SuperSmart
Ask about any prescription or over-the-counter medication and we check it for interactions with LJ-100 200 mg by SuperSmart — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of LJ-100 200 mg by SuperSmart
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
LJ-100 contains one active ingredient: Eurycoma longifolia, a plant extract at 200 mg per capsule. It also includes two inactive ingredients — acacia gum and white rice flour — which are binders and fillers that hold the capsule together.
Does it work?
Moderate evidence
The evidence for Eurycoma longifolia is mixed and limited. It's rated possibly effective for increasing sexual desire, but possibly ineffective for athletic performance.
For back pain, osteoporosis, and diabetes, there isn't enough reliable evidence in our data to rate whether it works. If you're considering this supplement for one of those uses, talk with your doctor about whether the current evidence supports it for your situation.
How safe is it?
Well-documented data
Eurycoma longifolia is generally well tolerated in short-term studies, but long-term safety and the quality of products on the market remain uncertain. One concern is that it may raise testosterone levels, and if your testosterone goes too high, you could experience testosterone-related side effects like acne, insulin resistance, or liver damage.
Because of possible hormonal effects and limited safety data, this supplement is not recommended during pregnancy or while breastfeeding — talk with your doctor or pharmacist if you're pregnant, planning pregnancy, or nursing and interested in this product.
Meds to double-check
Moderate interaction found
Before taking LJ-100, double-check with your doctor or pharmacist if you take propranolol (Inderal) or any other beta-blocker — Eurycoma longifolia can weaken its effects. Also flag any testosterone products you're on, and any medications broken down by your liver's CYP1A2, CYP2C19, or CYP2A6 enzymes, since levels of those drugs might rise.
Use the interaction checker below to confirm your exact medications.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
LJ-100 might appeal to someone interested in sexual desire support, but the evidence for other uses is weak or unknown. The main caution is its interaction with propranolol and its potential to raise testosterone — if you take heart medications, hormones, or drugs processed by certain liver enzymes, you'll need to check with your doctor or pharmacist before adding this.
Long-term safety isn't well established, so it's worth discussing your individual situation with your healthcare provider.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about LJ-100 200 mg, straight from the product label.
| Brand | SuperSmart |
|---|---|
| Barcode (UPC) | 5453003823339 |
| Net contents | 60 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2023 |
| DSLD ID | 285285 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for LJ-100 200 mg by SuperSmart, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| LJ-100 | 200 mg | -- |
Other ingredients: Acacia Gum, White Rice Flour
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Dietary Supplement
Formula
LJ-100 200 mg per day
Each capsule contains 100 mg of LJ-100.
LJ-100 - HP Ingredients.
Suggested/Recommended/Usage/Directions
Recommended Use: Adults. As a maintenance dose, take one or two vegetarian capsules a day at a convenient time, and/or one hour before sexual activity.
Precautions
Precautions: Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet.
Keep out of childrens' reach.
As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.
Storage
Store away from direct light, heat and humidity.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
LJ-100 200 mg by SuperSmart label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in LJ-100 200 mg by SuperSmart
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
LJ-100
Interacts with248 drugs
Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...
LJ-100 monograph & interactionsOther (inactive) ingredients: Acacia Gum, White Rice Flour. These complete the product’s ingredient list but are not active constituents.
LJ-100 200 mg by SuperSmart Drug Interactions
HelloPharmacist Interaction Report
LJ-100 by SuperSmart contains Eurycoma longifolia, which interacts with medications in several important ways.
The most serious concern is with propranolol (Inderal), a beta-blocker for heart and blood pressure — Eurycoma longifolia can reduce how well your body keeps this drug on board, cutting its levels by roughly 29% in a small study and potentially weakening its effects.
Read the full breakdown — every affected drug type, severity by severity
Eurycoma longifolia may also increase blood levels of drugs broken down by three liver enzymes: CYP1A2 substrates, CYP2C19 substrates, and CYP2A6 substrates. These effects were seen in lab studies only and haven't been confirmed in people, but the concern is theoretical.
Additionally, if you take testosterone therapy or supplements, Eurycoma longifolia might push levels higher — a clinical study showed it raised testosterone in aging men with low levels.
Altogether, these interactions span 248 individual medications. Before you start this supplement, run your current medications through the interaction checker on this page, and talk with your doctor or pharmacist about whether it's right for you — especially if you're on propranolol, testosterone products, or any drug metabolized by those liver pathways.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against LJ-100 200 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in LJ-100 200 mg interact with 248 drugs. Click any drug to see the details.
1 of the 1 ingredient in LJ-100 200 mg interact with drugs. Each result below shows which ingredient is responsible. LJ-100
Hydrochlorothiazide, PropranololInderide
How Hydrochlorothiazide, Propranolol interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Propranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Lj-100 + Hydrochlorothiazide, Propranolol interactionPropranololAngilol, Bedranol SR, Beta Prograne, Half Beta Prograne, Half-Inderal LA, Inderal +6 more
How Propranolol interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Propranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Lj-100 + Propranolol interactionPropranolol HydrochlorideHemangeol
How Propranolol Hydrochloride interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Propranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Lj-100 + Propranolol Hydrochloride interactionAbrocitinibCibinqo
How Abrocitinib interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Lj-100 + Abrocitinib interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with LJ-100 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj-100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj-100 + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in LJ-100 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
LJ-100
Propranolol (Inderal)
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.
Cytochrome P450 2A6 (Cyp2A6) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.
Testosterone
Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.
Brand information
Manufacturer and brand details for LJ-100 200 mg, from the product label.
SuperSmart
See all SuperSmart products- Name
- SN Worldwide Unipessoal, Lda
- Street Address
- Avenida Do Infante 66, Edificio Quinta Avenida 1 C
- City
- Funchal
- ZipCode
- 9000-015
LJ-100 200 mg by SuperSmart: Common Questions
Does LJ-100 200 mg by SuperSmart interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is LJ-100 and what is it supposed to do?
Can I take this if I'm pregnant or breastfeeding?
What are the side effects I should watch for?
Does this interact with a lot of medications?
Is this supplement safe to take long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if LJ-100 200 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind LJ-100 200 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
LJ-100 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Eurycoma Longifolia 4 references
- Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
- Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
- Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
- Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC