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Dietary supplement

Longjack 100:1 Tongkat Ali extract Ingredients & Drug Interactions

by Hard Rhino

Longjack 100:1 Tongkat Ali extract label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Longjack 100:1 Tongkat Ali extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Longjack 100:1 Tongkat Ali extract is a dietary supplement by Hard Rhino with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Longjack Tongkat Ali. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Longjack 100:1 Tongkat Ali extract by Hard Rhino

Ask about any prescription or over-the-counter medication and we check it for interactions with Longjack 100:1 Tongkat Ali extract by Hard Rhino — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Longjack 100:1 Tongkat Ali extract by Hard Rhino

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Longjack Tongkat Ali, a 100:1 extract of the Eurycoma longifolia root — meaning the extract is concentrated to be 100 times stronger than the raw plant material. Maltodextrin is included as an inactive ingredient to carry the extract in powder form.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: male sexual function and testosterone support.
  • We looked for evidence on: Age-related testosterone deficiency, Athletic performance, Erectile dysfunction (ED), Male Infertility, Muscle strength, Sexual desire — and 3 related terms.
  • The strongest evidence on file: Eurycoma Longifolia is rated "Possibly Effective" for Sexual desire (Natural Medicines).
  • Also on file: Eurycoma Longifolia is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Eurycoma Longifolia is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Muscle strength, Age-related testosterone deficiency, Male Infertility.

The evidence we hold shows Longjack Tongkat Ali is possibly effective for sexual desire. For athletic performance, the data suggests it's possibly ineffective.

For back pain, osteoporosis, and diabetes, there isn't enough reliable evidence yet to say one way or the other.

The evidence, ingredient by ingredient Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use in studies appears to be generally well tolerated, but long-term safety and the quality of products on the market aren't well established. Because this extract may raise testosterone levels, the safety data advises against use during pregnancy and while breastfeeding.

If elevated testosterone does develop, there's a risk of testosterone-related side effects including acne, insulin resistance, and liver stress.

Side effects, ingredient by ingredient Eurycoma Longifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you use propranolol (Inderal) or any other beta-blocker — this extract can reduce how well it works. You'll also want to confirm any prescription medications processed by your liver (your pharmacist can tell you if yours are), since this extract may theoretically raise their levels.

If you take testosterone therapy, mention this supplement too.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Longjack Tongkat Ali may help with sexual desire, but it's not proven for athletic performance or pain. If you take propranolol or other heart medications, or if you're on any prescription drug, check with your doctor or pharmacist before starting — this extract can interfere with how your body processes many medications.

Avoid it if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Longjack 100:1 Tongkat Ali extract, straight from the product label.

Brand Hard Rhino
Barcode (UPC) 798711500345
Net contents 5 kg; 11 lbs
Market status On market
Date entered into DSLD Apr 25, 2017
DSLD ID 72168
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Longjack 100:1 Tongkat Ali extract by Hard Rhino, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.3 Gram(s)
Maximum serving Sizes:
0.3 Gram(s)
Servings per container
16666
UPC/BARCODE
798711500345
IngredientAmount% DV
Longjack Tongkat Ali300 mg--

Other ingredients: Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

-Non-GMO -Gluten free -Allergen free

Allergens: This product contains no soy, dairy, dairy byproducts, eggs, shellfish, wheat, gluten, tree nuts, or sesame seeds.

General Statements

Bulk pail - Best value - Scoop inside - 16666 servings

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 scant scoop (~300 mg) mixed with 6-8 ounces of water or suitable beverage. Taken 1-3 times daily, preferably with meals or as directed by your qualified health professional. Consider taking in cycles, 1-day “on” and 2-days “off”. A micro scale is recommended to ensure accurate and precise measurements.

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases.

Precautions

Warning: Keep out of the reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions and/or taking prescription drug(s) or OTC medication(s).

Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions and/or taking prescription drug(s) or OTC medication(s).

Always consult with a qualified health physician before taking any new dietary supplement.

Do not use or consume if seal is broken.

FDA Statement of Identity

Dietary Supplement

Storage

Storage: Store in a cool, dry place. Re-seal inner bag immediately after use to preserve freshness.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Longjack 100:1 Tongkat Ali extract by Hard Rhino label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Longjack 100:1 Tongkat Ali extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Longjack 100:1 Tongkat Ali extract by Hard Rhino

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.3 Gram(s) Dosage formPowder Servings per container16666 Amounts shown are per serving.

Longjack Tongkat Ali

Interacts with
248 drugs
300 mg per serving

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

Longjack Tongkat Ali monograph & interactions

Other (inactive) ingredients: Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Longjack 100:1 Tongkat Ali extract by Hard Rhino Drug Interactions

Want to check YOUR meds against Longjack 100:1 Tongkat Ali extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
3 Moderate 245 Minor

Ingredients driving the most interactions

Longjack Tongkat Ali 248

Individual Drug Interactions

The ingredients in Longjack 100:1 Tongkat Ali extract interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in Longjack 100:1 Tongkat Ali extract interact with drugs. Each result below shows which ingredient is responsible. Longjack Tongkat Ali

Each ingredient & the kinds of drugs it affects

For each ingredient in Longjack 100:1 Tongkat Ali extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Longjack Tongkat Ali5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
Longjack Tongkat Ali full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Longjack 100:1 Tongkat Ali extract, from the product label.

Hard Rhino

See all Hard Rhino products
Name
Guardian Wholesale
City
Phoenix
State
AZ
ZipCode
85085
Phone Number
(866)961-8378
Web Address
HardRhino.com
Pharmacist Counseling Corner

Longjack 100:1 Tongkat Ali extract by Hard Rhino: Common Questions

Does Longjack 100:1 Tongkat Ali extract by Hard Rhino interact with any medications?
Yes. Based on its ingredients, Longjack 100:1 Tongkat Ali extract has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Longjack 100:1 Tongkat Ali extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Longjack Tongkat Ali actually work for sexual desire?
The evidence we hold rates it as possibly effective for sexual desire, meaning there's some support but it's not definitive. Talk with your doctor about whether it makes sense for your situation.
Can I take this while I'm pregnant or breastfeeding?
No — the safety data advises against it during both pregnancy and breastfeeding. Not enough is known about how it affects the baby or nursing infant, and its potential to raise hormone levels adds to the concern.
What are the side effects?
Short-term studies show it's generally well tolerated. However, if it raises your testosterone levels too high, you could develop acne, insulin resistance, liver stress, or other testosterone-related effects. Long-term safety isn't well established.
Can it really affect how many medications work?
Yes — this extract can interfere with how your liver processes drugs, and many common medications (248 individual ones across several categories) are handled that way. That's why checking your specific medications is so important.
What's inside — is there anything else I should know?
The product is Longjack Tongkat Ali extract plus maltodextrin, a powder carrier. It's a single-ingredient active supplement.
Is this safe to take long-term?
The research we have covers short-term use. Long-term safety and the consistency of product quality across brands aren't well established, so this isn't something to assume is safe indefinitely without talking to your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Longjack 100:1 Tongkat Ali extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Longjack 100:1 Tongkat Ali extract label
Go deeper

The Full Monographs Behind Longjack 100:1 Tongkat Ali extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Eurycoma Longifolia

Interacts with 248 drugs

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....

Read the full Eurycoma Longifolia monograph →
Sources

Sources & How We Checked

Longjack 100:1 Tongkat Ali extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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