Longjack 300 Tongkat Ali 300 mg Ingredients & Drug Interactions
by LuckyHerbs
What is this page for?
First and foremost: checking Longjack 300 Tongkat Ali 300 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Longjack 300 Tongkat Ali 300 mg is a dietary supplement by LuckyHerbs with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tongkat Ali Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Longjack 300 Tongkat Ali 300 mg by LuckyHerbs
Ask about any prescription or over-the-counter medication and we check it for interactions with Longjack 300 Tongkat Ali 300 mg by LuckyHerbs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Longjack 300 Tongkat Ali 300 mg by LuckyHerbs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This supplement contains one active ingredient: Tongkat Ali root extract at 300 mg per capsule. Tongkat Ali, also called Eurycoma longifolia, is a Southeast Asian plant root traditionally used for sexual function and general vitality.
The capsule itself is filled with inactive ingredients — cellulose, silica, and magnesium stearate — which are standard binders and flow agents.
Does it work?
Moderate evidence
The evidence for Tongkat Ali is mixed and limited. For sexual desire, there's some clinical backing — it's rated possibly effective based on available studies.
For athletic performance, the evidence suggests it's probably not helpful (possibly ineffective). For back pain, osteoporosis, and diabetes, there simply isn't enough reliable research to say whether it works or doesn't.
If sexual function is your reason for trying it, the data leans cautiously in your favor, but talk it over with your doctor first.
How safe is it?
Well-documented data
Tongkat Ali is generally well tolerated in short-term studies, but long-term safety data is thin and product quality can vary widely — that's a gap worth knowing. There's one notable caution: because this supplement may raise testosterone levels, if your testosterone goes above the normal range, you could develop testosterone-related side effects like acne, insulin resistance, or liver toxicity.
Because of possible hormonal effects and limited safety data, the evidence advises against use during pregnancy and breastfeeding.
Meds to double-check
Moderate interaction found
Check your medications before taking this supplement if you take propranolol (Inderal) or any other blood pressure medicine — Tongkat Ali can reduce how well they work. You'll also want to confirm with your doctor or pharmacist if you're on any drug that your liver breaks down using CYP1A2, CYP2C19, or CYP2A6 enzymes, or if you're taking testosterone replacement.
No interactions are documented for other types of drugs, but the search tool on this page lets you verify your exact medications.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Tongkat Ali may help with sexual desire based on current evidence, but it's not proven for athletic performance or other uses. The real question is how it'll interact with your specific medications — especially propranolol and other drugs your liver processes.
If you're pregnant, breastfeeding, or taking hormonal medications, this isn't the right choice. Talk with your doctor or pharmacist before starting it to make sure it fits your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Longjack 300 Tongkat Ali 300 mg, straight from the product label.
| Brand | LuckyHerbs |
|---|---|
| Barcode (UPC) | 810026422720 |
| Net contents | 60 Veg Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2023 |
| DSLD ID | 283224 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Women (not pregnant or lactating), Adult Male (18-50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Longjack 300 Tongkat Ali 300 mg by LuckyHerbs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Tongkat Ali Root Extract | 300 mg | -- |
Other ingredients: Cellulose, Powder, Cellulose, Silica, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested usage: Take 1 capsule daily as needed, or as recommended by your healthcare practitioner.
Formula
Eurycoma longifolia Jack is the scientific name for what is more commonly known as Tongkat Ali, Malaysian Ginseng, or Longjack. Although every part of the tongkat ali plant is used by traditional herbalists of Southeast Asia, its root is especially prized. Tongkat ali is known to possess various naturally occurring bioactive compounds, including Eurypeptides and Saponins.
This product delivers 300 mg non-GMO tongkat ali extract per capsule.
Men's support formula
Eurycoma longifolia Jack extract
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Caution: For adults only.
This product is not intended for those with a serious medical condition or pregnant/nursing women. Consult your physician if taking any medication.
Keep out of reach of children.
Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Do not eat freshness packet.
General Statements
1 year happiness guarantee
Please recycle.
Brand IP Statement(s)
Lucky Herbs Herbal Supplements by Lucky Vitamin
FDA Statement of Identity
Dietary Supplement
Formulation
Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.
Produced in a GMP facility that processes other ingredients containing these allergens. Natural color variation may occur in this product.
V Vegan
Storage
Keep in bottle. Store in a cool, dry place after opening.
Seals/Symbols
Guaranteed quality & potency
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Longjack 300 Tongkat Ali 300 mg by LuckyHerbs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Longjack 300 Tongkat Ali 300 mg by LuckyHerbs
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Veg Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Tongkat Ali Root Extract
Interacts with248 drugs
Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...
Tongkat Ali Root Extract monograph & interactionsOther (inactive) ingredients: Cellulose, Powder, Cellulose, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Longjack 300 Tongkat Ali 300 mg by LuckyHerbs Drug Interactions
HelloPharmacist Interaction Report
Longjack 300 by LuckyHerbs contains Tongkat Ali root extract, which does interact with medications.
The most serious concern is with propranolol (Inderal), a heart and blood pressure medication — Tongkat Ali can reduce how well it works, lowering its levels in your blood by about 29% in a small study.
Read the full breakdown — every affected drug type, severity by severity
Tongkat Ali may also affect how your body processes several other medication types. It can theoretically increase levels of drugs broken down by CYP1A2 enzymes, CYP2C19 enzymes, and CYP2A6 enzymes — though these effects have only been seen in lab studies so far, not yet confirmed in people.
Additionally, because Tongkat Ali may raise testosterone levels, it could add to the effect if you're already taking testosterone replacement therapy.
Altogetherther, these interactions span 248 individual medications. Before you start this supplement, check your exact prescription and over-the-counter drugs with the search tool on this page, and talk with your doctor or pharmacist — especially if you take propranolol or any blood pressure medicine.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Longjack 300 Tongkat Ali 300 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Longjack 300 Tongkat Ali 300 mg interact with 248 drugs. Click any drug to see the details.
1 of the 1 ingredient in Longjack 300 Tongkat Ali 300 mg interact with drugs. Each result below shows which ingredient is responsible. Tongkat Ali Root Extract
Hydrochlorothiazide, PropranololInderide
How Hydrochlorothiazide, Propranolol interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Tongkat Ali Root Extract + Hydrochlorothiazide, Propranolol interactionPropranololAngilol, Bedranol SR, Beta Prograne, Half Beta Prograne, Half-Inderal LA, Inderal +6 more
How Propranolol interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Tongkat Ali Root Extract + Propranolol interactionPropranolol HydrochlorideHemangeol
How Propranolol Hydrochloride interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Tongkat Ali Root Extract + Propranolol Hydrochloride interactionAbrocitinibCibinqo
How Abrocitinib interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Tongkat Ali Root Extract + Abrocitinib interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Longjack 300 Tongkat Ali 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Longjack 300 Tongkat Ali 300 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Tongkat Ali Root Extract
Propranolol (Inderal)
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.
Cytochrome P450 2A6 (Cyp2A6) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.
Testosterone
Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.
Brand information
Manufacturer and brand details for Longjack 300 Tongkat Ali 300 mg, from the product label.
LuckyHerbs
See all LuckyHerbs products- Name
- Lucky Health Group Inc.
- City
- Conshohocken
- State
- PA
- ZipCode
- 19428
- Phone Number
- 1-888-635-0474
- Web Address
- www.LuckyVitamin.com
Longjack 300 Tongkat Ali 300 mg by LuckyHerbs: Common Questions
Does Longjack 300 Tongkat Ali 300 mg by LuckyHerbs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does Tongkat Ali actually improve sexual function?
Can I take this if I'm pregnant or breastfeeding?
What are the side effects?
Will this work for back pain or osteoporosis?
What's the difference between this and other Tongkat Ali products?
Can I use this if I'm on testosterone replacement?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Longjack 300 Tongkat Ali 300 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Longjack 300 Tongkat Ali 300 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Longjack 300 Tongkat Ali 300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
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The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Eurycoma Longifolia 4 references
- Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
- Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
- Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
- Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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