Lumbrokinase Enzymes Delayed Release Ingredients & Drug Interactions
by Dr. Mercola
What is this page for?
First and foremost: checking Lumbrokinase Enzymes Delayed Release against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Lumbrokinase Enzymes Delayed Release is a dietary supplement by Dr. Mercola with 2 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Lumbrokinase Enzymes Delayed Release by Dr. Mercola
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains 2 active ingredients: protease and lumbrokinase, both fibrinolytic enzymes — meaning they're designed to help break down fibrin (a clotting protein) in your bloodstream. The delayed-release capsule is meant to deliver these enzymes to your small intestine rather than your stomach.
The rest of the ingredients are inactive — microcrystalline cellulose, hydroxypropyl methylcellulose, gellan gum, rice husk, and ascorbyl palmitate — which serve as fillers, binders, and preservatives to hold the capsule together.
Does it work?
Couldn't assess
We don't hold effectiveness ratings for protease or lumbrokinase in our data, so we can't tell you what the evidence shows for this product's intended purpose. If you're considering it, ask your pharmacist or doctor what the clinical evidence supports for fibrinolytic enzyme supplementation.
How safe is it?
Well-documented data
Protease is generally well tolerated in most adults, though digestive upset or allergic reactions are possible in some people. In rare cases, occupational exposure to airborne protease enzymes has triggered allergic reactions like hay fever symptoms or asthma in sensitive individuals — this isn't a typical risk from taking a supplement by mouth, but it's on the record.
Safety data during pregnancy advises against use unless prescribed by your doctor. During breastfeeding, there's little safety data, so medical advice is needed before using.
Meds to double-check
No known interactions
No interactions are documented for the ingredients we could check. That said, because this product contains enzymes that may affect clotting, anyone on blood thinners (anticoagulants), antiplatelet drugs, or medications that affect blood clotting should double-check with their pharmacist before starting.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This product is designed for people interested in fibrinolytic enzyme support, but the evidence we hold doesn't establish how well it works. If you're on blood thinners or any clotting-related medication, check with your pharmacist first.
Protease is generally well tolerated, but pregnant women should avoid it unless their doctor prescribes it, and nursing mothers should get personalized advice.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Lumbrokinase Enzymes Delayed Release, straight from the product label.
| Brand | Dr. Mercola |
|---|---|
| Barcode (UPC) | 810094213336 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 23, 2025 |
| DSLD ID | 327180 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Lumbrokinase Enzymes Delayed Release by Dr. Mercola, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Protease | 0 NP | -- |
| Lumbrokinase | 0 NP | -- |
| Dr. Mercola's Fibrinolytic Enzyme Blend | 11 mg | -- |
Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Gellan Gum, Rice Husk, Ascorbyl Palmitate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: Adults, as a dietary supplement, take one (1) capsule daily on an empty stomach.
Precautions
Keep out of reach of children.
Do not use if safety seal is broken.
If you are nursing, pregnant, have a blood coagulation or other medical condition, or are taking medications such as anticoagulants, consult your physician before taking this product.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
Blood flow support Delayed release Brain & Cognitive function
FDA Statement of Identity
Dietary Supplement
General Statements
Providing quality products since 2001.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Lumbrokinase Enzymes Delayed Release by Dr. Mercola label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Lumbrokinase Enzymes Delayed Release by Dr. Mercola
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dr. Mercola's Fibrinolytic Enzyme Blend
- › Protease
- › Lumbrokinase
Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Gellan Gum, Rice Husk, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.
Lumbrokinase Enzymes Delayed Release by Dr. Mercola Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Lumbrokinase Enzymes Delayed Release. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Lumbrokinase Enzymes Delayed Release, from the product label.
Dr. Mercola
See all Dr. Mercola products- Name
- NHP
- Street Address
- 125 SW 3rd Place
- City
- Cape Coral
- State
- FL
- ZipCode
- 33991
- Phone Number
- (877) 985-2696
Lumbrokinase Enzymes Delayed Release by Dr. Mercola: Common Questions
Does Lumbrokinase Enzymes Delayed Release by Dr. Mercola interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What exactly is protease, and what does it do in this product?
Can I take this while pregnant?
Is it safe to breastfeed while taking this?
Can protease cause allergic reactions?
Does this product contain any fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Lumbrokinase Enzymes Delayed Release is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Lumbrokinase Enzymes Delayed Release’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Lumbrokinase Enzymes Delayed Release's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC