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Dietary supplement

Lyc-O-Mato 20 mg Ingredients & Drug Interactions

by Protocol For Life Balance

Lyc-O-Mato 20 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lyc-O-Mato 20 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lyc-O-Mato 20 mg is a dietary supplement by Protocol For Life Balance with 1 active ingredient. Its ingredients are commonly taken for heart health, prostate health, antioxidant support.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lycopene. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lyc-O-Mato 20 mg by Protocol For Life Balance

Ask about any prescription or over-the-counter medication and we check it for interactions with Lyc-O-Mato 20 mg by Protocol For Life Balance — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lyc-O-Mato 20 mg by Protocol For Life Balance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Lyc-O-Mato contains one active ingredient: lycopene, a naturally occurring carotenoid (plant pigment) sourced here in a softgel form. The softgel capsule also contains rice bran oil as an inactive ingredient to help with absorption.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Supports Prostate Health.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Prostate cancer.
  • The strongest evidence on file: Lycopene is rated "Possibly Effective" for Prostate cancer (Natural Medicines).
  • Also on file: Lycopene is rated "Insufficient Reliable Evidence To Rate" for Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS).

The evidence for lycopene varies by condition. It's rated possibly effective for prostate cancer.

For bladder cancer and diabetes, the evidence suggests it's probably not effective. For high cholesterol (hyperlipidemia), exercise-induced asthma, and ALS (Lou Gehrig's disease), there isn't enough reliable evidence yet to know whether it works.

The evidence, ingredient by ingredient Lycopene

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lycopene from food is considered safe, and supplement doses are generally well tolerated. The most common side effects are gastrointestinal—diarrhea, gas, bloating, nausea, vomiting, upset stomach, or loss of appetite.

One case of chest pain was reported in a pregnant woman taking a different lycopene product at a much lower dose, though lycopene's role in that event wasn't confirmed. For pregnancy and breastfeeding, the safety data is limited for supplements, though lycopene from food is fine.

Talk with your doctor or pharmacist about whether this supplement is right for you if you're pregnant or nursing.

Side effects, ingredient by ingredient Lycopene

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lycopene.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this product, double-check your medications with your doctor or pharmacist if you take any blood thinners or antiplatelet drugs (such as warfarin, apixaban, dabigatran, aspirin, or clopidogrel). Lycopene may increase bleeding risk when combined with these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Lyc-O-Mato may be worth considering if you're interested in prostate health support, though the evidence is modest. If you take any blood thinners or antiplatelet medications, you'll need to check with your doctor or pharmacist before adding this supplement—the interaction risk is real.

Gastrointestinal side effects are possible, especially at higher doses. Chat with your own healthcare provider to see if it's a fit for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lyc-O-Mato 20 mg, straight from the product label.

Brand Protocol For Life Balance
Barcode (UPC) 707359130623
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Jul 25, 2013
DSLD ID 23737
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lyc-O-Mato 20 mg by Protocol For Life Balance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
707359130623
IngredientAmount% DV
Lycopene20 mg--

Other ingredients: Rice Bran Oil, Softgel Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

CAUTIONS/INTERACTIONS: There are no known drug interactions.

Produced in a GMP facility that processes other ingredients containing these allergens.

Do not eat Packet.

General

CODE P3062 V4

Formula

• Natural Lycopene

- Supports Prostate Health*

FDA Statement of Identity

A Dietary Supplement

Seals/Symbols

GMP

Brand IP Statement(s)

One softgel of Protocol For Life Balance(R) LYC-O-MATO(R) supplies 20 mg of Lycopene (from Natural Tomato Extract).

LYC-O-MATO(R) is a registered trademark of LycoRed Natural Products Ltd.

This bottle contains an AGELESS(R) oxygen absorbing packet to ensure fresshness.

Storage

Store in a cool, dry place after opening.

General Statements

Please Recycle.

HOW IT WORKS: Natural Lycopene is a powerful carotenoid and the pigment that gives tomatoes, watermelon, and pink grapefruit their characteristic red color. Clinical studies have indicated that natural Lycopene works through a number of mechanisms to support cardiovascular health and healthy immune function.* In addition, epidemiological studies have determined that natural Lycopene may be particularly important for the support of prostate health, as well as for the health of the digestive tract.*

Formulated by doctors and clinical scientists exclusively for licensed healthcare practitioners.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

SUGGESTED USAGE: As a dietary supplement, take 1 softgel daily, perferably with a meal, or as directed by your healthcare practitioner.

Formulation

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lyc-O-Mato 20 mg by Protocol For Life Balance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lyc-O-Mato 20 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lyc-O-Mato 20 mg by Protocol For Life Balance

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Lycopene

Interacts with
122 drugs
20 mg per serving Form: natural Tomato extract

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...

Lycopene monograph & interactions

Other (inactive) ingredients: Rice Bran Oil, Softgel Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lyc-O-Mato 20 mg by Protocol For Life Balance Drug Interactions

Want to check YOUR meds against Lyc-O-Mato 20 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Lycopene 122

Individual Drug Interactions

The ingredients in Lyc-O-Mato 20 mg interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lyc-O-Mato 20 mg interact with drugs. Each result below shows which ingredient is responsible. Lycopene

Each ingredient & the kinds of drugs it affects

For each ingredient in Lyc-O-Mato 20 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lycopene1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.

Likelihood Possible Evidence D
Lycopene full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lyc-O-Mato 20 mg, from the product label.

Protocol For Life Balance

See all Protocol For Life Balance products
Name
Protocol For Life Balance(R)
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Pharmacist Counseling Corner

Lyc-O-Mato 20 mg by Protocol For Life Balance: Common Questions

Does Lyc-O-Mato 20 mg by Protocol For Life Balance interact with any medications?
Yes. Based on its ingredients, Lyc-O-Mato 20 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lyc-O-Mato 20 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Lyc-O-Mato if I'm pregnant?
The safety data on lycopene supplements during pregnancy is limited. While lycopene from food is fine, talk with your doctor before taking a supplement to see if it's right for you and your pregnancy.
Can I take this while breastfeeding?
There isn't enough safety data on lycopene supplements while breastfeeding. Lycopene from food is fine, but check with your doctor or pharmacist before using the supplement.
What side effects might I experience?
Gastrointestinal effects are the most common: diarrhea, gas, bloating, nausea, vomiting, upset stomach, or loss of appetite. These are usually mild, but let your doctor know if they're bothersome or don't settle down.
Does lycopene really help with prostate health?
The evidence suggests it may help, which is why it's rated possibly effective for prostate cancer. The data isn't rock-solid, though, so it shouldn't replace standard medical care or screening.
Why does this product contain rice bran oil?
Rice bran oil is included as an inactive ingredient in the softgel to help your body absorb the lycopene better.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lyc-O-Mato 20 mg label
Go deeper

The Full Monographs Behind Lyc-O-Mato 20 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lycopene

Interacts with 122 drugs

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...

Read the full Lycopene monograph →
Sources

Sources & How We Checked

Lyc-O-Mato 20 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lycopene 10 references
  1. Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
  2. Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
  3. Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
  4. O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
  5. Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
  6. Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J.Urol. 2009;181(3):1098-1103. PubMed
  7. Banerjee, S., Jeyaseelan, S., and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J.Obstet.Gynaecol.Res. 2009;35(3):477-482. PubMed
  8. Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
  9. Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
  10. Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed

See these in context on the Lycopene monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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