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Dietary supplement

Lycopene 15 mg Ingredients & Drug Interactions

by Wonder Laboratories

Lycopene 15 mg label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lycopene 15 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lycopene 15 mg is a dietary supplement by Wonder Laboratories with 2 active ingredients. Its ingredients are commonly taken for high cholesterol, digestive health and fiber, heart health support.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lycopene. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lycopene 15 mg by Wonder Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Lycopene 15 mg by Wonder Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lycopene 15 mg by Wonder Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains 2 active ingredients: lycopene (15 mg) and rice bran oil. Lycopene is a red-orange carotenoid found naturally in tomatoes and other fruits; rice bran oil is a plant oil derived from the outer layer of rice grain.

Both are included for their potential health effects. The softgel also contains several inactive ingredients — gelatin, glycerin, purified water, medium-chain triglycerides, yellow beeswax, and silica — that make up the capsule shell and help deliver the contents.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: heart and prostate function support.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Cardiovascular disease (CVD), Dyslipidemia, Hyperlipidemia, Prostate cancer, Cardiovascular health — and 1 related terms.
  • The strongest evidence on file: Lycopene is rated "Possibly Effective" for Prostate cancer (Natural Medicines).
  • Also on file: Rice Bran is rated "Possibly Effective" for Dyslipidemia.
  • Also on file: Lycopene is rated "Insufficient Reliable Evidence To Rate" for Benign prostatic hyperplasia (BPH), Cardiovascular disease (CVD), Hyperlipidemia.

Lycopene shows possibly effective evidence for prostate cancer, but the data on other conditions — including bladder cancer, diabetes, high cholesterol, ALS, and exercise-induced asthma — is either possibly ineffective or not strong enough to rate. Rice bran oil is possibly effective for managing abnormal blood lipid levels (dyslipidemia), but shows possibly ineffective evidence for colorectal cancer prevention, and insufficient evidence for alopecia areata (hair loss).

Neither ingredient has strong proof for the other conditions studied.

The evidence, ingredient by ingredient Rice Bran Lycopene

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lycopene supplements are generally well tolerated. Rice bran oil is generally safe as a food, but concentrated supplement doses have less safety data and may cause digestive side effects like abdominal discomfort, gas, and loose stools — especially when you first start or increase the amount.

Both ingredients rarely trigger allergic reactions; rice bran can cause hives, swelling, wheezing, or in very rare cases, anaphylaxis. Stop and seek emergency help if you develop difficulty breathing or severe swelling.

For pregnancy, rice bran oil is likely safe, and lycopene from food and supplements both appear likely safe — though supplement lycopene in pregnancy hasn't been extensively studied, so confirm with your doctor. During breastfeeding, lycopene supplement safety isn't well established; check with your healthcare provider.

Side effects, ingredient by ingredient Rice Bran Lycopene

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Lycopene.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take any blood thinners or antiplatelet drugs (such as warfarin, aspirin, clopidogrel, or dabigatran) — lycopene may increase bleeding risk. Also confirm you've never had an allergic reaction to rice or rice products.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may interest you if you're looking into lycopene for prostate health or rice bran oil for cholesterol support, and you don't take blood thinners or antiplatelet medications. If you do take those drugs, or you have a rice bran allergy, talk with your doctor or pharmacist before starting.

Digestive side effects like gas and loose stools are common early on — they usually settle down.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lycopene 15 mg, straight from the product label.

Brand Wonder Laboratories
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Dec 18, 2021
DSLD ID 262753
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lycopene 15 mg by Wonder Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
IngredientAmount% DV
Rice Bran Oil230 mg--
Lycopene15 mg--

Other ingredients: Gelatin, Glycerin, purified Water, Medium Chain Triglycerides, yellow Beeswax, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Lycopene nutritionally supports healthy heart and prostate function. Lycopene also possesses antioxidant properties that neutralize cell-damaging free radicals.

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Antioxidant neutralizes free radicals

Gluten free

Made in USA

Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing, consult your physician before taking this product.

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Formula 638

Formula

LYC-O-MATO Natural tomato

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

LYC-O-MATO is a trademark of LycoRed. LYC-O-MATO Natural tomato Lycopene

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 softgel daily.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lycopene 15 mg by Wonder Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lycopene 15 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lycopene 15 mg by Wonder Laboratories

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Rice Bran Oil

No known
interactions
230 mg per serving

Rice bran is the nutrient-rich outer layer of the rice grain and is a good source of fiber, healthy fats, and plant compounds. It is most studied for...

Rice Bran Oil monograph & interactions

Lycopene

Interacts with
122 drugs
15 mg per serving Form: Lyc-O-Mato Natural Tomato

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...

Lycopene monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Purified Water, Medium Chain Triglycerides, Yellow Beeswax, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lycopene 15 mg by Wonder Laboratories Drug Interactions

Want to check YOUR meds against Lycopene 15 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Lycopene 122

Individual Drug Interactions

The ingredients in Lycopene 15 mg interact with 122 drugs. Click any drug to see the details.

1 of the 2 ingredients in Lycopene 15 mg interact with drugs. Each result below shows which ingredient is responsible. Lycopene

Each ingredient & the kinds of drugs it affects

For each ingredient in Lycopene 15 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lycopene1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.

Likelihood Possible Evidence D
Lycopene full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lycopene 15 mg, from the product label.

Wonder Laboratories

See all Wonder Laboratories products
Name
Wonder Laboratories
Street Address
115 S.C.T. Ct.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Lycopene 15 mg by Wonder Laboratories: Common Questions

Does Lycopene 15 mg by Wonder Laboratories interact with any medications?
Yes. Based on its ingredients, Lycopene 15 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lycopene 15 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me diarrhea?
Gastrointestinal side effects like diarrhea, gas, bloating, and nausea can happen with lycopene supplements. Rice bran can also cause loose stools, gas, and abdominal discomfort, especially at first. These effects are usually mild and temporary, but if they're severe or don't improve, stop and talk with your pharmacist.
Is this safe during pregnancy?
Rice bran oil appears likely safe in pregnancy, and lycopene from food or supplements looks likely safe too. That said, lycopene supplements haven't been studied extensively in pregnant people, so run this past your doctor before taking it to make sure it's right for your situation.
Can I take this while breastfeeding?
Rice bran oil is likely safe while breastfeeding. Lycopene from food is fine, but there isn't much safety data on lycopene supplements during breastfeeding, so check with your doctor or pharmacist first.
What is lycopene actually for?
Lycopene is a red carotenoid from tomatoes and similar fruits. It's possibly effective for prostate cancer prevention or management, but the evidence for other uses — like bladder cancer, diabetes, or high cholesterol — is weak or not established. It's a popular supplement for general antioxidant support, though proof is limited.
Does rice bran oil really help with cholesterol?
Rice bran oil is possibly effective for managing abnormal blood lipid levels. However, the evidence for preventing colorectal cancer is weak, and there's not enough data on its effects for hair loss. It's one tool among many if you're working on cholesterol.
Can I be allergic to this?
Yes. Rice bran can trigger allergic reactions ranging from hives and itching to swelling and wheezing, and very rarely anaphylaxis. If you've never eaten rice bran before or suspect an allergy, start cautiously or ask your doctor first. Stop immediately and seek emergency help if you develop breathing trouble or severe swelling.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lycopene 15 mg label
Go deeper

The Full Monographs Behind Lycopene 15 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rice Bran

Rice bran is the nutrient-rich outer layer of the rice grain and is a good source of fiber, healthy fats, and plant compounds. It is most studied for helping lower cholesterol, but for most...

Read the full Rice Bran monograph → Herb & supplement monograph

Lycopene

Interacts with 122 drugs

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...

Read the full Lycopene monograph →
Sources

Sources & How We Checked

Lycopene 15 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rice Bran 7 references
  1. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  2. Fujiwaki T, Furusho K. The effects of rice bran broth bathing in patients with atopic dermatitis. Acta Paediatr Jpn 1992;34:505-10.
  3. Uenotsuchi T, Satoh E, Kiryu H, Yano Y. Pyemotes dermatitis caused by indirect contact with husk rice. Br J Dermatol 2000;143:680-2. DOI
  4. Satoh R, Tsuge I, Tokuda R, Teshima R. Analysis of the distribution of rice allergens in brown rice grains and of the allergenicity of products containing rice bran. Food Chem. 2019;276:761-767. PubMed
  5. Togashi Y, Inomata N, Suzuki A, Hakuta A, Aihara M. Pediatric case with rice bran allergy induced by epicutaneous sensitization in a family rice shop. Allergol Int. 2019;68(1):117-118. PubMed
  6. So WKW, Chan JYW, Law BMH, et al. Effects of a Rice Bran Dietary Intervention on the Composition of the Intestinal Microbiota of Adults with a High Risk of Colorectal Cancer: A Pilot Randomised-Controlled Trial. Nutrients 2021;13(2):526. PubMed
  7. Haneda Y, Kadowaki S, Furui M, Taketani T. A pediatric case of food-dependent exercise-induced anaphylaxis due to rice bran. Asia Pac Allergy 2021;11(1):e4. PubMed

See these in context on the Rice Bran monograph →

Lycopene 10 references
  1. Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
  2. Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
  3. Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
  4. O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
  5. Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
  6. Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J.Urol. 2009;181(3):1098-1103. PubMed
  7. Banerjee, S., Jeyaseelan, S., and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J.Obstet.Gynaecol.Res. 2009;35(3):477-482. PubMed
  8. Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
  9. Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
  10. Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed

See these in context on the Lycopene monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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