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Dietary supplement

Lycopene With Lyc-O-Mato 10 mg Ingredients & Drug Interactions

by Doctor's Best

Lycopene With Lyc-O-Mato 10 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lycopene With Lyc-O-Mato 10 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lycopene With Lyc-O-Mato 10 mg is a dietary supplement by Doctor's Best with 1 active ingredient. Its ingredients are commonly taken for heart health, prostate health, antioxidant support.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lycopene. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lycopene With Lyc-O-Mato 10 mg by Doctor's Best

Ask about any prescription or over-the-counter medication and we check it for interactions with Lycopene With Lyc-O-Mato 10 mg by Doctor's Best — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lycopene With Lyc-O-Mato 10 mg by Doctor's Best

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: 10 mg of lycopene, a carotenoid (a plant pigment) found naturally in tomatoes and other red fruits. The remaining ingredients are inert carriers—rice bran oil, medium chain triglycerides, beeswax, and silica—that make up the softgel capsule itself.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lycopene's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support cardiovascular health and reduce blood pressure.
  • We looked for evidence on: Cardiovascular disease (CVD), Hypertension, Hyperlipidemia, Atherosclerosis, Cholesterol management, Vascular function — and 1 related terms.
  • The closest evidence on file: Lycopene is rated "Insufficient Reliable Evidence To Rate" for Atherosclerosis (Natural Medicines).
  • Also on file: Lycopene is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD), Hyperlipidemia, Hypertension.

Lycopene is possibly effective for prostate cancer based on available evidence. For other conditions in this product's marketing—bladder cancer, diabetes, high cholesterol (hyperlipidemia), ALS, and exercise-induced asthma—the evidence is either weak (possibly ineffective for bladder cancer and diabetes) or too sparse to evaluate (insufficient evidence for the others).

If you're considering it for a specific health goal, talk with your doctor about whether the current evidence supports that use.

The evidence, ingredient by ingredient Lycopene

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lycopene from food is considered safe, and supplement doses are generally well tolerated. The main side effects reported with lycopene supplements are gastrointestinal: diarrhea, gas, bloating, nausea, vomiting, indigestion, and loss of appetite.

A single case of chest pain was reported in a pregnant woman taking a lycopene product, though it's unclear whether lycopene was the cause. Pregnancy and breastfeeding safety data on supplements is limited; food amounts are fine, but the safety data advises against lycopene supplements during pregnancy and breastfeeding unless your doctor advises otherwise.

Side effects, ingredient by ingredient Lycopene

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lycopene.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs such as warfarin, aspirin, clopidogrel, or similar medications. Lycopene may increase bleeding risk when combined with these drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Lycopene may be worth considering if you're interested in prostate cancer support and have discussed it with your doctor. If you take any blood thinner or blood-thinning medication, check with your doctor or pharmacist before starting this product.

Gastrointestinal side effects are possible, and pregnant or breastfeeding women should avoid supplements unless cleared by their healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lycopene With Lyc-O-Mato 10 mg, straight from the product label.

Brand Doctor's Best
Barcode (UPC) 753950004245
Net contents 120 Softgel(s)
Market status On market
Date entered into DSLD Jul 25, 2016
DSLD ID 63244
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lycopene With Lyc-O-Mato 10 mg by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
60
UPC/BARCODE
753950004245
IngredientAmount% DV
Lycopene20 mg--

Other ingredients: Rice Bran Oil, Medium Chain Triglycerides, yellow Beeswax, Silica, Softgel Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Lycopene is a potent antioxidant, packed with phytonutrients, and the body’s most common carotenoid found in the liver, adrenal glands, lungs, prostate, colon, and skin.

Helps provide antioxidants that may be lacking in the diet* Helps support cardiovascular health by reducing blood pressure and cholesterol* Helps prevent oxidative damage in biological systems (DNA, lipids and proteins)*

Helps provide antioxidants that may be lacking in the diet* Helps support cardiovascular health by reducing blood pressure and cholesterol* Helps prevent oxidative damage in biological systems (DNA, lipids and proteins)*

HELPS SUPPORT CARDIOVASCULAR HEALTH*

10 mg

Brand IP Statement(s)

Doctor’s Best Lycopene with Lyc-O-Mato may help maintain healthy LDL oxidation and may protect against free radical activity at the arterial wall.* Lyco-O-Mato has been shown to help lower blood pressure and to help vascular function.*

Science-Based Nutrition

Lyc-O-Mato is a registered trademark of LycoRed, Natural Products Industries, Ltd.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

YDRB424

Formula

Lycopene With Lyc-O-Mato Tomato Nutrient Complex

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Adult Use: Take 2 softgels daily with or without food, or as recommended by a nutritionally-informed physician.

Formulation

Non-GMO / Gluten Free / Soy Free

Non-GMO / Gluten Free / Soy Free

Storage

Store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lycopene With Lyc-O-Mato 10 mg by Doctor's Best label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lycopene With Lyc-O-Mato 10 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lycopene With Lyc-O-Mato 10 mg by Doctor's Best

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Lycopene

Interacts with
122 drugs
20 mg per serving Form: Lyc-O-Mato

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...

Lycopene monograph & interactions

Other (inactive) ingredients: Rice Bran Oil, Medium Chain Triglycerides, Yellow Beeswax, Silica, Softgel Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lycopene With Lyc-O-Mato 10 mg by Doctor's Best Drug Interactions

Want to check YOUR meds against Lycopene With Lyc-O-Mato 10 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Lycopene 122

Individual Drug Interactions

The ingredients in Lycopene With Lyc-O-Mato 10 mg interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lycopene With Lyc-O-Mato 10 mg interact with drugs. Each result below shows which ingredient is responsible. Lycopene

Each ingredient & the kinds of drugs it affects

For each ingredient in Lycopene With Lyc-O-Mato 10 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lycopene1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.

Likelihood Possible Evidence D
Lycopene full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lycopene With Lyc-O-Mato 10 mg, from the product label.

Doctor's Best

See all Doctor's Best products
Name
Doctor's Best, Inc.
State
California
Phone Number
(800) 777-2474
Web Address
www.drbvitamins.com
Pharmacist Counseling Corner

Lycopene With Lyc-O-Mato 10 mg by Doctor's Best: Common Questions

Does Lycopene With Lyc-O-Mato 10 mg by Doctor's Best interact with any medications?
Yes. Based on its ingredients, Lycopene With Lyc-O-Mato 10 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lycopene With Lyc-O-Mato 10 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against lycopene supplements during pregnancy and breastfeeding. Food amounts are fine, but supplements aren't well studied in these situations. Talk with your doctor or pharmacist for personalized advice.
What side effects should I expect?
Most people tolerate it well, but some experience gastrointestinal effects like diarrhea, gas, bloating, nausea, or indigestion. If these occur, mention them to your pharmacist.
Does lycopene actually work for prostate cancer?
The evidence rates it as possibly effective for prostate cancer. For other conditions this product is sometimes marketed for—bladder cancer, diabetes, high cholesterol, and ALS—the evidence is either weak or not yet established.
Is this the same as eating tomatoes?
Lycopene is the active compound in tomatoes and other red fruits, but this is a concentrated supplement dose rather than whole food. If you eat plenty of tomatoes, you're already getting lycopene; a supplement adds to that.
Why do I need to check my blood thinner before taking this?
Lab research shows lycopene has mild blood-thinning properties. If you already take a blood thinner or antiplatelet drug, adding lycopene could increase your bleeding risk. Your doctor or pharmacist needs to review your specific medications first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lycopene With Lyc-O-Mato 10 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lycopene With Lyc-O-Mato 10 mg label
Go deeper

The Full Monographs Behind Lycopene With Lyc-O-Mato 10 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lycopene

Interacts with 122 drugs

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...

Read the full Lycopene monograph →
Sources

Sources & How We Checked

Lycopene With Lyc-O-Mato 10 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lycopene 10 references
  1. Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
  2. Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
  3. Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
  4. O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
  5. Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
  6. Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J.Urol. 2009;181(3):1098-1103. PubMed
  7. Banerjee, S., Jeyaseelan, S., and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J.Obstet.Gynaecol.Res. 2009;35(3):477-482. PubMed
  8. Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
  9. Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
  10. Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed

See these in context on the Lycopene monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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