Mandarin Fruit Powder Ingredients & Drug Interactions
by TerraVita Premium Collection
What is this page for?
First and foremost: checking Mandarin Fruit Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Mandarin Fruit Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for source of vitamin c, digestive support, aromatherapy and relaxation.Based on those ingredients, 643 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Mandarin, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Mandarin Fruit Powder by TerraVita Premium Collection
Ask about any prescription or over-the-counter medication and we check it for interactions with Mandarin Fruit Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Mandarin Fruit Powder by TerraVita Premium Collection
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: mandarin powder. That's it — there are no other active ingredients or fillers listed.
Does it work?
Couldn't assess
The evidence we hold rates mandarin for cancer prevention as insufficient to establish effectiveness. We have no data on other uses for this product.
How safe is it?
Well-documented data
Mandarin fruit as food is generally well tolerated with very few reported side effects. However, a complete safety review has not been done, and the facts note that concentrated extracts and essential oils carry more caution and should be used only under medical advice.
Topically, mandarin essential oil has been linked to contact dermatitis (skin irritation) in isolated reports. This product is a powder, not an essential oil or concentrated extract, which is a meaningful difference.
The safety data on this product during pregnancy and lactation is not on file. If you're pregnant or breastfeeding, talk with your doctor or pharmacist for personalized advice.
Meds to double-check
Minor interactions only
If you take midazolam (Versed) or other medications metabolized by the CYP3A4 enzyme system in your liver, check with your pharmacist before adding this product. The interaction is Minor in severity, but it's worth confirming your specific drugs aren't affected.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.
Mandarin Fruit Powder is a single-ingredient product made from the whole fruit. If you don't take midazolam or CYP3A4-metabolized drugs, the documented interaction risk is low.
If you do take medications processed by your liver, check them against the tool below first. Talk to your pharmacist if you're unsure.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Mandarin Fruit Powder, straight from the product label.
| Brand | TerraVita Premium Collection |
|---|---|
| Barcode (UPC) | 064435207649 |
| Net contents | 4 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2023 |
| DSLD ID | 291187 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Mandarin Fruit Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Mandarin, Powder | 1000 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
A Dietary Supplement
Brand IP Statement(s)
Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Suggested/Recommended/Usage/Directions
Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.
General Statements
TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.
Please recycle!
FDA Disclaimer Statement
Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Mandarin Fruit Powder by TerraVita Premium Collection label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Mandarin Fruit Powder by TerraVita Premium Collection
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container113 Amounts shown are per serving.
Mandarin, Powder
Interacts with643 drugs
Tangerine is a sweet citrus fruit that is a good source of vitamin C and other nutrients, and is widely enjoyed as food. While the peel and essential...
Mandarin, Powder monograph & interactionsMandarin Fruit Powder by TerraVita Premium Collection Drug Interactions
HelloPharmacist Interaction Report
TerraVita Premium Collection Mandarin Fruit Powder contains one active ingredient — mandarin powder — which has documented interactions with certain medications.
The most serious concern is with midazolam (Versed), a sedative used during medical procedures. In lab studies, tangeretin (a compound in mandarin) appeared to speed up how your body breaks down midazolam by up to 52%.
However, human studies using 200 mL of tangerine juice showed only a slight delay in absorption with no actual change in how the body metabolized the drug.
Read the full breakdown — every affected drug type, severity by severity
Beyond midazolam, mandarin may theoretically affect other medications metabolized by the CYP3A4 enzyme system in your liver — a large group of drugs. The interaction is rated Minor in severity.
The key caveat is that most evidence comes from lab work; real-world effects in people appear modest or absent, as the juice study demonstrated.
If you take any prescription medication, especially sedatives or other drugs processed through CYP3A4, check your exact medications with the search tool below before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Mandarin Fruit Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Mandarin Fruit Powder interact with 643 drugs. Click any drug to see the details.
1 of the 1 ingredient in Mandarin Fruit Powder interact with drugs. Each result below shows which ingredient is responsible. Mandarin, Powder
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Abiraterone Acetate interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acalabrutinib interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Mandarin Fruit Powder — through 1 ingredient. Tap an ingredient for the detail:
Mandarin, PowderCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Mandarin, Powder + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Mandarin Fruit Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Mandarin, Powder
Cytochrome P450 3A4 (Cyp3A4) Substrates
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4). This suggests that tangeretin may stimulate CYP3A4 activity. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam, a CYP3A4 substrate. Theoretically, tangerine juice might increase CYP3A4 activity and decrease levels of drugs metabolized by this enzyme. However, this effect is unlikely.
Some drugs metabolized by CYP3A4 include amitriptyline (Elavil), amiodarone (Cordarone), citalopram (Celexa), felodipine (Plendil), lansoprazole (Prevacid), ondansetron (Zofran), prednisone (Deltasone, Orasone), sertraline (Zoloft), sibutramine (Meridia), and many others.
Midazolam (Versed)
In vitro, tangeretin, a constituent of tangerine, appears to increase the metabolism of midazolam in human liver microsomes by up to 52%. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam. Theoretically, tangerine juice might increase the metabolism and reduce the effects of midazolam. However, this effect is unlikely.
Brand information
Manufacturer and brand details for Mandarin Fruit Powder, from the product label.
TerraVita Premium Collection
See all TerraVita Premium Collection products- Name
- TerraVita Fine Whole Herbs
- City
- Brampton
- State
- Ontario
Mandarin Fruit Powder by TerraVita Premium Collection: Common Questions
Does Mandarin Fruit Powder by TerraVita Premium Collection interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe to take with my blood pressure or cholesterol medication?
Will this work for cancer prevention?
Are there fillers or other junk in this powder?
Is the powdered form safer than mandarin essential oil?
Can I take this while pregnant?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Mandarin Fruit Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Mandarin Fruit Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Mandarin Fruit Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Tangerine 3 references
- Yuan, J. M., Wang, X. L., Xiang, Y. B., Gao, Y. T., Ross, R. K., and Yu, M. C. Preserved foods in relation to risk of nasopharyngeal carcinoma in Shanghai, China. Int J Cancer 2000;85(3):358-363. DOI
- Backman, J. T., Maenpaa, J., Belle, D. J., Wrighton, S. A., Kivisto, K. T., and Neuvonen, P. J. Lack of correlation between in vitro and in vivo studies on the effects of tangeretin and tangerine juice on midazolam hydroxylation. Clin Pharmacol Ther 2000; PubMed
- Vilaplana, J. and Romaguera, C. Contact dermatitis from the essential oil of tangerine in fragrance. Contact Dermatitis 2002;46(2):108. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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