Major interaction on record — check this product against your medications before combining. Based on 5 of 11 ingredients. Check your meds →
Dietary supplement

Master Blaster Sour Heads Ingredients & Drug Interactions

by Bang

Master Blaster Sour Heads label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Master Blaster Sour Heads against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Master Blaster Sour Heads is a dietary supplement by Bang with 11 active ingredients. Its ingredients are commonly taken for improving high-intensity exercise performance, building muscle strength and size, sports and athletic training.Based on those ingredients, 756 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Caffeine Anhydrous, L-Citrulline Malate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Master Blaster Sour Heads by Bang

Ask about any prescription or over-the-counter medication and we check it for interactions with Master Blaster Sour Heads by Bang — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Master Blaster Sour Heads by Bang

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 11 of its 11 active ingredients.
  • “Branched-Chain Amino Acids” is listed as a grouped ingredient — the label gives one combined amount (7,500 mg) without saying how much of each component you get.

Master Blaster Sour Heads is a 11-ingredient powder with three amino acid building blocks (L-leucine, L-isoleucine, L-valine), creatine monohydrate for muscle and strength, caffeine anhydrous for energy and focus, beta-alanine to support athletic performance, L-citrulline malate for blood flow, betaine anhydrous, branched-chain amino acids as a blend, highly branched cyclic dextrin (a carbohydrate), creatyl-L-leucine, and RS5. The product contains no inactive fillers — what you see is the active blend.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: potent brain and body fuel for athletic performance.
  • We looked for evidence on: Athletic performance, Physical performance, Cognitive function, Mental alertness, Muscle strength, Exercise-induced muscle soreness — and 3 related terms.
  • The strongest evidence on file: Caffeine is rated "Likely Effective" for Athletic performance (Natural Medicines).
  • Also on file: Caffeine is rated "Likely Effective" for Mental alertness.
  • Also on file: Creatine is rated "Possibly Effective" for Athletic performance, Muscle strength.

Creatine in this product is possibly effective for muscle strength, athletic performance, and sarcopenia (age-related muscle loss), and possibly effective for rare cerebral creatine deficiency syndromes; it's possibly ineffective for osteopenia and Huntington disease. Beta-alanine is possibly effective for athletic and physical performance, though evidence is insufficient for cognition, COPD, and menopausal symptoms.

L-citrulline is possibly effective for athletic performance. Caffeine is likely effective for mental alertness and athletic performance, and effective for neonatal apnea and postoperative headache.

Betaine is effective for homocystinuria and possibly effective for elevated homocysteine levels; evidence is insufficient for liver disease, colon polyps, depression, and reflux. Evidence for the other ingredients we checked is not established in our data.

The evidence, ingredient by ingredient Creatine Beta-alanine Caffeine Betaine Anhydrous L-citrulline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Creatine is generally well tolerated in healthy adults, though those with kidney problems should be careful — case reports mention kidney injury and muscle breakdown (rhabdomyolysis) as rare serious side effects. Common mild side effects include dehydration, diarrhea, muscle cramps, and water retention; about a quarter of people with ALS reported swelling with high-dose creatine.

Beta-alanine is generally well tolerated but commonly causes harmless skin tingling (paresthesia) and flushing, usually starting on the scalp within 20 minutes and lasting about an hour. Caffeine in moderate doses is generally safe for healthy adults but can cause anxiety, insomnia, jitteriness, tremors, nausea, and stomach upset; high doses carry rare risk of stroke.

L-citrulline is generally well tolerated with mild gastrointestinal discomfort or heartburn as the main side effects. Betaine is generally well tolerated but can cause body odor, nausea, diarrhea, and stomach upset; rarely, cerebral edema has been reported.

Side effects, ingredient by ingredient Creatine Beta-alanine Caffeine Betaine Anhydrous L-citrulline

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 5 matched ingredients can interact with medications — Caffeine, L-citrulline.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 756 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take ephedrine (major risk for dangerous stimulant effects), blood pressure medications, erectile dysfunction drugs (sildenafil, tadalafil), pentobarbital, phenobarbital, carbamazepine, clozapine, quinolone antibiotics, cimetidine, or dipyridamole. No interactions are documented for creatine, beta-alanine, or betaine among the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Master Blaster Sour Heads is aimed at people training for athletic performance and muscle building; caffeine and creatine in particular have evidence behind them. If you take blood pressure medication, erectile dysfunction drugs, stimulants, sedatives, anticonvulsants, antipsychotics, or certain antibiotics, you'll need to check your exact medications before using this product.

Anyone with kidney disease, pregnant or nursing, or with concerns about caffeine sensitivity should talk with their doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Master Blaster Sour Heads, straight from the product label.

Brand Bang
Net contents 1.21 lb(s); 548 Gram(s)
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 278503
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Master Blaster Sour Heads by Bang, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
27.4 Gram(s)
Maximum serving Sizes:
27.4 Gram(s)
Servings per container
20
IngredientAmount% DV
Calories8 Calorie(s)--
L-Leucine3000 mg--
L-Isoleucine3000 mg--
Creatine Monohydrate5000 mg--
L-Valine1500 mg--
Beta-Alanine2400 mg--
Caffeine Anhydrous350 mg--
Total Carbohydrate2 Gram(s)--
Branched-Chain Amino Acids7500 mg--
Betaine Anhydrous2500 mg--
L-Citrulline Malate6000 mg--
Highly Branched Cyclic Dextrin10 mg--
Creatyl-L-Leucine250 mg--
RS51990 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Potent Brain and Body Fuel Make no mistake- New Bang Master Blaster is not your stereotypical life-sucking / muscle destroying pre-workout "concentrate". The very definition of BANG screams scientific breakthrough!

GLUTEN FREE GMO FREE

Pre-workout

The Master Blaster to build muscle faster University proven performance enhancer

Formula

Infused with Patented water-stable super creatine -- Bang triggered a major paradigm shift among the performance and bodybuilding authorities and has now become the most disruptive scientific innovation in the 30-year history of sports nutrition! In a very short period, Bang beverage has risen to the top; consequently, generating unrelenting consumer demand for the Bang Master Blaster pre-workout. Bang Master Blaster is designed around the Patented Super Creatine-Amino acid di-Peptide that is far more soluble than regular Creatine and L-Leucine. Furthermore, the New Bang Master Blaster pre-workout contains massive doses of clean performance enhancing and bodybuilding ingredients designed to work in concert with Super Creatine. All ingredients are fully disclosed on the label because we are proud that Bang Master Blaster is the most potent, best tasting pre-workout supplement in history!

This product contains caffeine and should not be used with any other caffeine containing products.

Sour Heads Natural and artificial flavors

Brand IP Statement(s)

Infused with Patented water-stable super creatine -- Bang triggered a major paradigm shift among the performance and bodybuilding authorities and has now become the most disruptive scientific innovation in the 30-year history of sports nutrition! Bang Master Blaster is designed around the Patented Super Creatine-Amino acid di-Peptide that is far more soluble than regular Creatine and L-Leucine.

VPX Live powerfully US PATENT 8,445,466

Copyright 2017 Vital Pharmaceuticals, Inc. All Rights Reserved.

Precautions

Caution: Do not use this product if you are pregnant or nursing. Do not consume this product if you are taking any prescription drug and/or have any medical condition.

The user of this product assumes all liability if this product is used in a manner not consistent with label guidelines. This product contains caffeine and should not be used with any other caffeine containing products. This product is intended for use by healthy individuals only over 18 years of age.

To report a serious adverse event or obtain product information, contact Vital Pharmaceuticals, Inc. 1600 North Park Drive Weston, FL 33326 USA 954.641.0570 vpxsports.com

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Made in USA from Domestic & Imported Ingredients Manufactured for VPX

General Statements

Instagram BANGENERGY Facebook VPXSPORTS

Please recycle

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Master Blaster Sour Heads by Bang label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Master Blaster Sour Heads label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Master Blaster Sour Heads by Bang

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size27.4 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Creatine Monohydrate

No known
interactions
5000 mg per serving

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...

Creatine Monohydrate monograph & interactions

Beta-Alanine

No known
interactions
2400 mg per serving

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

Beta-Alanine monograph & interactions

Caffeine Anhydrous

Interacts with
655 drugs
350 mg per serving

Caffeine is a natural stimulant found in coffee, tea, and many other plants and products. In moderate amounts it can boost alertness and reduce tiredn...

Caffeine Anhydrous monograph & interactions

Branched-Chain Amino Acids

7500 mg per serving
  • › L-Leucine
  • › L-Isoleucine
  • › L-Valine

Betaine Anhydrous

No known
interactions
2500 mg per serving

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and a...

Betaine Anhydrous monograph & interactions

L-Citrulline Malate

Interacts with
178 drugs
6000 mg per serving

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. I...

L-Citrulline Malate monograph & interactions

Highly Branched Cyclic Dextrin

10 mg per serving

Creatyl-L-Leucine

250 mg per serving

RS5

1990 mg per serving Form: Hydroxypropyl Distarch Phosphate
Interaction report

Master Blaster Sour Heads by Bang Drug Interactions

Want to check YOUR meds against Master Blaster Sour Heads?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
756Drugs
8 Major 586 Moderate 162 Minor

Ingredients driving the most interactions

Caffeine Anhydrous 655
L-Citrulline Malate 178

Individual Drug Interactions

The ingredients in Master Blaster Sour Heads interact with 756 drugs. Click any drug to see the details.

2 of the 11 ingredients in Master Blaster Sour Heads interact with drugs. Each result below shows which ingredient is responsible. Caffeine Anhydrous L-Citrulline Malate

Each ingredient & the kinds of drugs it affects

For each ingredient in Master Blaster Sour Heads with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Caffeine Anhydrous41 drug types · 655 drugs

Ephedrine

Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Use of ephedrine with caffeine can increase the risk of stimulatory adverse effects. There is evidence that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction, stroke, seizures, and death.

Likelihood Probable Evidence D
Adenosine (Adenocard)

Theoretically, caffeine might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Some evidence shows that caffeine is a competitive inhibitor of adenosine and can reduce the vasodilatory effects of adenosine in humans. However, other research shows that caffeine does not seem to affect supplemental adenosine because high interstitial levels of adenosine overcome the antagonistic effects of caffeine. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. However, methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.

Likelihood Possible Evidence B
Anticoagulant/Antiplatelet Drugs

Theoretically, caffeine may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Caffeine is reported to have antiplatelet activity. Theoretically, it might increase the risk of bleeding when used concomitantly with these agents; however, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Beta-Adrenergic Agonists

Theoretically, large amounts of caffeine might increase the cardiac inotropic effects of beta-agonists.

Likelihood Probable Evidence D
Carbamazepine (Tegretol)

Theoretically, caffeine might reduce the effects of carbamazepine and increase the risk for convulsions.
Animal research suggests that taking caffeine can lower the anticonvulsant effects of carbamazepine and can induce seizures when taken in doses above 400 mg/kg. Human research has shown that taking caffeine 300 mg in three divided doses along with carbamazepine 200 mg reduces the bioavailability of carbamazepine by 32% and prolongs the plasma half-life of carbamazepine 2-fold in healthy individuals.

Likelihood Possible Evidence D
Cimetidine (Tagamet)

Theoretically, cimetidine might increase the levels and adverse effects of caffeine.
Cimetidine decreases the rate of caffeine clearance by 31% to 42%.

Likelihood Likely Evidence B
Clozapine (Clozaril)

Caffeine might increase the levels and adverse effects of clozapine and acutely exacerbate psychotic symptoms.
Caffeine might increase the effects and toxicity of clozapine. Caffeine doses of 400-1000 mg per day inhibit clozapine metabolism. Clozapine is metabolized by cytochrome P450 1A2 (CYP1A2). Although researchers speculate that caffeine might inhibit CYP1A2, there is no reliable evidence that caffeine affects CYP1A2. There is also speculation that genetic factors might make some patients more sensitive to an interaction between clozapine and caffeine. In one case report, severe, life-threatening clozapine toxicity and multiorgan system failure occurred in a patient with schizophrenia stabilized on clozapine who consumed caffeine 600 mg daily.

Likelihood Possible Evidence B
Dipyridamole (Persantine)

Theoretically, caffeine might decrease the vasodilatory effects of dipyridamole and interfere with its use prior to stress testing.
Caffeine inhibits dipyridamole-induced vasodilation. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. Methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.

Likelihood Probable Evidence B
Disulfiram (Antabuse)

Theoretically, disulfiram use might increase the levels and adverse effects of caffeine.
Disulfiram decreases the rate of caffeine clearance.

Likelihood Probable Evidence B
Diuretic Drugs

Theoretically, using caffeine with diuretic drugs might increase the risk of hypokalemia.
Caffeine, especially in excessive amounts, can reduce potassium levels due to stimulation of the sodium-potassium pump. Diuretics can also cause lower potassium levels.

Likelihood Possible Evidence D
Estrogens

Theoretically, estrogens might increase the levels and adverse effects of caffeine.
Estrogen inhibits caffeine metabolism.

Likelihood Probable Evidence B
Ethosuximide (Zarontin)

Theoretically, caffeine might reduce the effects of ethosuximide and increase the risk for convulsions.
Animal research suggests that caffeine 92.4 mg/kg can decrease the anticonvulsant activity of ethosuximide. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Felbamate (Felbatol)

Theoretically, caffeine might reduce the effects of felbamate and increase the risk for convulsions.
Animal research suggests that a high dose of caffeine 161.7 mg/kg can decreases the anticonvulsant activity of felbamate. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Flutamide (Eulexin)

Theoretically, caffeine might increase the levels and adverse effects of flutamide.
In vitro evidence suggests that caffeine can inhibit the metabolism of flutamide. However, this effect has not been reported in humans.

Likelihood Probable Evidence D
Fluvoxamine (Luvox)

Theoretically, fluvoxamine might increase the levels and adverse effects of caffeine.
Fluvoxamine reduces caffeine metabolism.

Likelihood Probable Evidence D
Lithium

Abrupt caffeine withdrawal might increase the levels and adverse effects of lithium.
Caffeine has diuretic activity. When abruptly discontinued, caffeine may alter the clearance of lithium. There are two case reports of lithium tremor that worsened upon abrupt coffee withdrawal and 6 case reports of elevated serum lithium levels after reducing or eliminating caffeine intake. In one case, a male with schizoaffective disorder stabilized on lithium had an elevated lithium level after reducing his caffeine intake by 87%. At a later date, he increased his caffeine intake by 6-fold, resulting in a subtherapeutic lithium level and a recurrence of psychiatric symptoms.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use might increase the risk of a hypertensive crisis.
Caffeine has been shown to inhibit monoamine oxidase (MAO) A and B in laboratory studies. Concomitant intake of large amounts of caffeine with MAOIs might precipitate a hypertensive crisis. In a case report, a patient that consumed 10-12 cups of caffeinated coffee and took the MAOI tranylcypromine presented with severe hypertension. Hypertension was resolved after the patient switched to drinking decaffeinated coffee.

Likelihood Possible Evidence D
Nicotine

Theoretically, concomitant use might increase the risk of hypertension.
Concomitant use of caffeine and nicotine has been shown to have additive cardiovascular effects, including increased heart rate and blood pressure. Blood pressure was increased by 10.8/12.4 mmHg when the agents were used concomitantly.

Likelihood Probable Evidence B
Pentobarbital (Nembutal)

Theoretically, caffeine might decrease the effects of pentobarbital.
Caffeine might negate the hypnotic effects of pentobarbital.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

Theoretically, caffeine might reduce the effects of phenobarbital and increase the risk for convulsions.
Animal research suggests that caffeine can decrease the anticonvulsant activity of phenobarbital. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Phenylpropanolamine

Theoretically, phenylpropanolamine might increase the risk of hypertension, as well as the levels and adverse effects of caffeine.
Concomitant use of phenylpropanolamine and caffeine might cause an additive increase in blood pressure. Phenylpropanolamine also seems to increase caffeine serum levels.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Theoretically, caffeine might reduce the effects of phenytoin and increase the risk for convulsions.
Animal research suggests that caffeine can decrease the anticonvulsant activity of phenytoin. The effect does not seem to be related to the seizure threshold-lowering effects of caffeine. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Pioglitazone (Actos)

Theoretically, caffeine might increase the levels and clinical effects of pioglitazone.
Animal research suggests that caffeine can modestly increase the maximum concentration, area under the curve, and half-life of pioglitazone, and also reduce its clearance. This increased the antidiabetic effects of pioglitazone. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.
Quinolones (also called fluoroquinolones) can decrease caffeine clearance by inhibiting cytochrome P450 1A2 (CYP1A2) enzyme.

Likelihood Probable Evidence B
Riluzole (Rilutek)

Theoretically, concomitant use might increase the levels and adverse effects of both caffeine and riluzole.
Caffeine and riluzole are both metabolized by cytochrome P450 1A2 (CYP1A2), and concomitant use might reduce the metabolism of one or both agents.

Likelihood Possible Evidence D
Caffeine Anhydrous full monograph & all 41 interactions

L-Citrulline Malate2 drug types · 178 drugs

Antihypertensive Drugs

Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.

Likelihood Possible Evidence B
Phosphodiesterase-5 Inhibitors

Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
L-Citrulline Malate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Master Blaster Sour Heads, from the product label.

Bang

See all Bang products
Name
Vital Pharmaceuticals, Inc.
Street Address
1600 North Park Drive
City
Weston
State
FL
ZipCode
33326
Phone Number
954.641.0570
Web Address
vpxsports.com
Pharmacist Counseling Corner

Master Blaster Sour Heads by Bang: Common Questions

Does Master Blaster Sour Heads by Bang interact with any medications?
Yes. Based on its ingredients, Master Blaster Sour Heads has a known interaction with 756 medications, including 8 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Master Blaster Sour Heads contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's the caffeine dose in this powder?
The product facts don't specify the exact amount of caffeine anhydrous per serving, so check the label or contact the manufacturer for that detail.
Will this cause the tingling sensation I've heard about with pre-workouts?
Yes — beta-alanine commonly causes harmless skin tingling and flushing, usually starting on the scalp within 20 minutes of taking it and lasting about an hour. This is a normal, temporary side effect that gets milder at lower doses.
Is this safe if I have kidney problems?
No — creatine is a main ingredient here, and people with kidney issues should be careful with it. Talk to your doctor or pharmacist before using this product if you have any kidney disease or concerns.
Does this product work for muscle building?
Creatine in this blend is possibly effective for muscle strength, and L-citrulline is possibly effective for athletic performance, so there's evidence behind some of its ingredients. Results vary and depend on your training and diet too.
Can I take this if I'm pregnant or breastfeeding?
No — creatine, beta-alanine, and L-citrulline all lack sufficient safety data during pregnancy and breastfeeding and are best avoided. Caffeine has mixed evidence in pregnancy. Talk with your doctor or pharmacist about whether it's right for you.
Will this keep me awake at night?
Caffeine is in this product and commonly causes insomnia and sleep disturbances, so if you're sensitive to caffeine or take it late in the day, you may have trouble sleeping. Start with less if sleep is a concern.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Master Blaster Sour Heads is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Master Blaster Sour Heads label
Go deeper

The Full Monographs Behind Master Blaster Sour Heads’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Creatine

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...

Read the full Creatine monograph → Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph → Herb & supplement monograph

Caffeine

Interacts with 655 drugs

Caffeine is a natural stimulant found in coffee, tea, and many other plants and products. In moderate amounts it can boost alertness and reduce tiredness for most healthy adults, but too muc...

Read the full Caffeine monograph → Herb & supplement monograph

Betaine Anhydrous

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and as a prescription medicine for a rare gen...

Read the full Betaine Anhydrous monograph → Herb & supplement monograph

L-citrulline

Interacts with 178 drugs

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...

Read the full L-citrulline monograph →
Sources

Sources & How We Checked

Master Blaster Sour Heads's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 354 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Creatine 86 references
  1. Koshy KM, Griswold E, Schneeberger EE. Interstitial nephritis in a patient taking creatine. N Engl J Med 1999;340:814-5. PubMed
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