Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Creacore Lemon Lime Ingredients & Drug Interactions

by MuscleTech Concentrated Series

Creacore Lemon Lime label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Creacore Lemon Lime against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Creacore Lemon Lime is a dietary supplement by MuscleTech Concentrated Series with 2 active ingredients. Its ingredients are commonly taken for improving high-intensity exercise performance, building muscle strength and size, sports and athletic training.Based on those ingredients, 389 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fenugreek extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Creacore Lemon Lime by MuscleTech Concentrated Series

Ask about any prescription or over-the-counter medication and we check it for interactions with Creacore Lemon Lime by MuscleTech Concentrated Series — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Creacore Lemon Lime by MuscleTech Concentrated Series

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients: creatine HCl and fenugreek extract. Creatine helps your muscles produce energy during lifting and high-intensity exercise.

Fenugreek is a plant seed traditionally used for sexual function, menstrual comfort, and blood sugar support. The rest is inactive ingredients — flavoring, thickeners, acids, and sweeteners that give the powder its taste and texture.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Increased muscle growth and strength.
  • We looked for evidence on: Athletic performance, Muscle breakdown, Muscle cramps, Muscle strength, Physical performance, Sarcopenia — and 4 related terms.
  • The strongest evidence on file: Creatine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Creatine is rated "Possibly Effective" for Muscle strength, Sarcopenia.
  • Also on file: Fenugreek is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Muscle strength.

Creatine is possibly effective for building muscle strength, supporting athletic performance, and helping with sarcopenia (age-related muscle loss). It's also possibly effective for certain rare brain disorders, cerebral creatine deficiency syndromes.

The data shows it's not effective for Huntington disease or for building bone density. Fenugreek extract is possibly effective for sexual function and arousal, dysmenorrhea (menstrual pain), and diabetes — though for diabetes, the evidence is solid enough that clinical trials have shown it can lower blood sugar.

For other uses beyond these, the evidence we hold is not established.

The evidence, ingredient by ingredient Creatine Fenugreek

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Creatine is generally well tolerated in healthy adults. The most common side effects are dehydration, diarrhea, stomach upset, muscle cramps, and water retention.

People with kidney problems should be cautious. Creatine should be avoided during pregnancy and breastfeeding because safety data isn't available.

Fenugreek seed is generally well tolerated at food doses, but supplement amounts may cause stomach pain, bloating, diarrhea, nausea, and flatulence. Rare but serious allergic reactions — including swelling of the throat, difficulty breathing, and shock — have been reported.

Fenugreek should be avoided in pregnancy because it may affect the uterus. If you're nursing and considering fenugreek to boost milk supply, the evidence is limited; talk with your doctor or pharmacist first.

Side effects, ingredient by ingredient Creatine Fenugreek

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Fenugreek.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 389 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check if you're on blood thinners (anticoagulants) or antiplatelet drugs, diabetes medications, theophylline, phenytoin, metoprolol, clopidogrel, or sildenafil — fenugreek in this product interacts with all of these. These are Moderate-severity interactions.

If you take any of these drugs, run them through the checker on this page first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Creacore is designed for muscle building and athletic performance, thanks mainly to the creatine. It's suitable if you're training hard and tolerate creatine well.

If you take blood thinners, diabetes meds, or asthma or seizure medications, check with your pharmacist before starting — fenugreek can interact with these. Anyone with kidney concerns or pregnant or nursing should talk with their provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Creacore Lemon Lime, straight from the product label.

Brand MuscleTech Concentrated Series
Barcode (UPC) 631656703375
Net contents 9.81 oz.; 278 g
Market status On market
Date entered into DSLD Feb 25, 2015
DSLD ID 42690
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Creacore Lemon Lime by MuscleTech Concentrated Series, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3.5 Gram(s)
Maximum serving Sizes:
7 Gram(s)
Servings per container
80
UPC/BARCODE
631656703375
IngredientAmount% DV
Creatine HCl3500 mg, 1750 mg--
Fenugreek extract900 mg, 450 mg--

Other ingredients: Natural and Artificial flavors, Calcium Silicate, Citric Acid, Malic Acid, Sucralose, Acesulfame-Potassium, FD&C Yellow No. 5, FD&C Blue No. 1

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

More Creatine per Serving

For lot no. and expiry date: see bottle. Made in the U.S.A. from domestic and international ingredients.

World's First Double-Strength Concentrated Creatine

Increased Muscle Growth and Strength

In a 2011 published clinical study, subjects supplementing with this combination significantly increased their bench press one-rep max, leg press one-rep max and lean mass – all without having to add extra carbohydrates. Taylor et al., 2011. Journal of Sports Science and Medicine. 10:254-260.

Improved Creatine Uptake Researchers believe that ingesting fenugreek in combination with creatine may be an effective way for improving creatine uptake similarly to dextrose, without having to ingest large amounts of simple carbohydrates. Super-Concentrated Formula – No Cycling, No Loading and No Bloating

NEW & IMPROVED FLAVOR

Double-Strength Concentrated Creatine

Muscle - Strength - Power

OVER 2X MORE POTENT

POWERED BY CLINICALLY RESEARCHED DOSES

80 Super Concentrated Doses

Capture this QR code with a smartphone QR code reader to learn more about CreaCore. {QR code}

Brand IP Statement(s)

(C) 2013.

Choose CreaCore(TM).

Unlike the other concentrated creatine powder that recommends a “micro-dosing” protocol that can have you taking up to 4 scoops a day, CreaCore(R) delivers more creatine HCl in just 2 concentrated scoops. Not only does every bottle of CreaCore(R) deliver more value, it also delivers results supported by scientific research.

CreaCore(R) is formulated with a precise ratio of creatine and fenugreek extract (3500mg:900mg).

CreaCore(R) is manufactured according to cGMP standards, as is required for all dietary supplements.

Protected by U.S. patent #5,968,554.

Formula

CreaCore(R) represents the evolution of the concentrated creatine powder. Dosed with over 2x more creatine HCl per scoop, CreaCore(R) is also the first and only creatine formula to utilize a scientifically studied dose of fenugreek extract for improved effects. Don’t just take any creatine, choose one with superior ingredients.

Delivers 3.5g Creatine HCl Plus Fenugreek Extract 2-scoop serving

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Mix 1 serving (1 scoop) with 6-8 oz. of water once daily. For full effects, mix 2 scoops with 12-16 oz. of water. On workout days, consume immediately after your workout. Read the entire label before use and follow directions provided. As with all creatine products, maintain an adequate state of hydration during use.

Precautions

PROCESSED IN A FACILITY THAT ALSO PROCESSES MILK, EGG, WHEAT, SOY, PEANUT, AND TREE NUT, FISH AND SHELLFISH INGREDIENTS.

WARNING: Not intended for use by persons under 18.

Do not use if pregnant or nursing.

Discontinue use and consult a medical doctor if you experience unusual symptoms.

Consult a medical doctor before use if you have been treated for, or diagnosed with, or have a family history of any medical condition, or if you are using any prescription or over-the-counter drug(s), including blood thinners.

Consult a medical doctor before starting any diet or exercise program. Do not exceed recommended serving. Improper use of this product will not improve results and is not advised. Use only as directed. Do not use if packaging has been tampered with.

KEEP OUT OF REACH OF CHILDREN.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

8700US 0413

Storage

Store in a cool, dry place (60(0)F to 80(0)F).

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Creacore Lemon Lime by MuscleTech Concentrated Series label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Creacore Lemon Lime label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Creacore Lemon Lime by MuscleTech Concentrated Series

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size3.5 Gram(s) Dosage formPowder Servings per container80 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Creatine HCl

No known
interactions
3500 mg per serving

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...

Creatine HCl monograph & interactions

Fenugreek extract

Interacts with
389 drugs
900 mg per serving Form: Trigonella foenum-graecum

Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. So...

Fenugreek extract monograph & interactions

Other (inactive) ingredients: Natural and Artificial flavors, Calcium Silicate, Citric Acid, Malic Acid, Sucralose, Acesulfame-Potassium, FD&C Yellow No. 5, FD&C Blue No. 1. These complete the product’s ingredient list but are not active constituents.

Interaction report

Creacore Lemon Lime by MuscleTech Concentrated Series Drug Interactions

Want to check YOUR meds against Creacore Lemon Lime?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
389Drugs
224 Moderate 165 Minor

Ingredients driving the most interactions

Fenugreek extract 389

Individual Drug Interactions

The ingredients in Creacore Lemon Lime interact with 389 drugs. Click any drug to see the details.

1 of the 2 ingredients in Creacore Lemon Lime interact with drugs. Each result below shows which ingredient is responsible. Fenugreek extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Creacore Lemon Lime with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Fenugreek extract9 drug types · 389 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .

Likelihood Unlikely Evidence B
Antidiabetes Drugs

Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.

Likelihood Probable Evidence B
Clopidogrel (Plavix)

Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.

Likelihood Possible Evidence D
Metoprolol (Toprol)

Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Theophylline

Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.

Likelihood Possible Evidence D
Antihypertensive Drugs

Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.

Likelihood Possible Evidence C
Fenugreek extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Creacore Lemon Lime, from the product label.

MuscleTech Concentrated Series

See all MuscleTech Concentrated Series products
Name
Iovate Health Sciences U.S.A. Inc.
Street Address
1105 N. Market St., Ste. 1330
City
Wilmington
State
DE
ZipCode
19801
Pharmacist Counseling Corner

Creacore Lemon Lime by MuscleTech Concentrated Series: Common Questions

Does Creacore Lemon Lime by MuscleTech Concentrated Series interact with any medications?
Yes. Based on its ingredients, Creacore Lemon Lime has a known interaction with 389 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Creacore Lemon Lime contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does creatine do?
Creatine helps your muscles produce energy during heavy lifting and intense exercise, which can boost strength and athletic performance over time. The evidence shows it's possibly effective for building muscle and may help with age-related muscle loss.
Can I take this if I'm pregnant or breastfeeding?
No — creatine should be avoided during pregnancy because safety hasn't been established, and also during breastfeeding. Fenugreek should also be avoided during pregnancy. If you're nursing and interested in fenugreek for milk supply, the evidence is limited; talk with your doctor or pharmacist.
What are the most common side effects?
From creatine: dehydration, diarrhea, stomach upset, muscle cramps, and water retention. From fenugreek: stomach pain, bloating, diarrhea, nausea, and gas. Most people tolerate both well, but these can happen.
Is this safe if I have kidney problems?
People with kidney issues should be cautious with creatine. Talk with your doctor or pharmacist before starting — they can advise whether it's right for you and monitor you if you do take it.
Does fenugreek actually work for sexual function?
The evidence shows fenugreek is possibly effective for sexual dysfunction and arousal, so there's some research backing it. That said, results vary person to person, and it's not a cure.
Can fenugreek affect my blood sugar?
Yes — fenugreek can lower blood sugar, which is why it's possibly effective for diabetes. If you take diabetes medications, this could add up to a bigger drop; check with your pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Creacore Lemon Lime is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Creacore Lemon Lime label
Go deeper

The Full Monographs Behind Creacore Lemon Lime’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Creatine

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...

Read the full Creatine monograph → Herb & supplement monograph

Fenugreek

Interacts with 389 drugs

Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. Some early research is encouraging for blo...

Read the full Fenugreek monograph →
Sources

Sources & How We Checked

Creacore Lemon Lime's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 116 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Creatine 86 references
  1. Koshy KM, Griswold E, Schneeberger EE. Interstitial nephritis in a patient taking creatine. N Engl J Med 1999;340:814-5. PubMed
  2. Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
  3. Greenhaff P. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;352:233-4. PubMed
  4. Vandenberghe K, Goris M, Van Hecke P, et al. Long-term creatine intake is beneficial to muscle performance during resistance training (abstract). J Appl Physiol 1997;83:2055-63. PubMed
  5. Hultman E, Soderlund K, Timmons JA, et al. Muscle creatine loading in men. J Appl Physiol 1996;81:232-7. PubMed
  6. Pritchard NR, Kalra PA. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;351:1252-3. PubMed
  7. Poortmans JR, Auquier H, Renaut V, et al. Effect of short-term creatine supplementation on renal responses in men (abstract). Eur J Appl Physiol Occup Physiol 1997;76:566-7. PubMed
  8. Poortmans JR, Francaux M. Long-term oral creatine supplementation does not impair renal function in healthy athletes. Med Sci Sports Exerc 1999;31:1108-10. PubMed
  9. Mihic S, MacDonald JR, McKenzie S, Tarnopolsky MA. Acute creatine loading increases fat-free mass, but does not affect blood pressure, plasma creatinine, or CK activity in men and women. Med Sci Sports Exerc 2000;32:291-6. PubMed
  10. Rawson ES, Wehnert ML, Clarkson PM. Effects of 30 days of creatine ingestion in older men. Eur J Appl Physiol Occup Physiol 1999;80:139-44. PubMed
  11. Earnest CP, Almada AL, Mitchell TL. High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women. Clin Sci (Colch) 1996;91:113-8. PubMed
  12. Juhn MS. Oral creatine supplementation. Separating fact from hype. Phys Sportsmed 1999;27:47-50,53-54,56,61,89. PubMed
  13. Juhn MS, O'Kane JW, Vinci DM. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am Diet Assoc 1999;99:593-5.
  14. Green AL, Hultman E, Macdonald IA, et al. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am J Physiol 1996;271:E821-6. PubMed
  15. Balsom PD, Soderlund K, Sjodin B, Ekblom B. Skeletal muscle metabolism during short duration high-intensity exercise: influence of creatine supplementation. Acta Physiol Scand 1995;154:303-10. PubMed
  16. Snow RJ, McKenna MJ, Selig SE, et al. Effect of creatine supplementation on sprint exercise performance and muscle metabolism. (abstract) J Appl Physiol 1998;84:1667-73. PubMed
  17. McNaughton LR, Dalton B, Tarr J. The effects of creatine supplementation on high-intensity exercise performance in elite performers. (abstract) Eur J Appl Physiol Occup Physiol 1998;78:236-40. PubMed
  18. Groeneveld GJ, Veldink JH, van der Tweel I, et al. A randomized sequential trial of creatine in amyotrophic lateral sclerosis. Ann Neurol 2003;53:437-45. . PubMed
  19. Robinson SJ. Acute quadriceps compartment syndrome and rhabdomyolysis in a weight lifter using high-dose creatine supplementation. J Am Board Fam Pract 2000;13:134-7. PubMed
  20. Kammer RT. Lone atrial fibrillation associated with creatine monohydrate supplementation. Pharmacotherapy 2005;25:762-4. PubMed
  21. Gualano B, Ugrinowitsch C, Novaes RB, et al. Effects of creatine supplementation on renal function: a randomized, double-blind, placebo-controlled clinical trial. Eur J Appl Physiol 2008;103:33-40. PubMed
  22. Pfeffer, G., Majamaa, K., Turnbull, D. M., Thorburn, D., and Chinnery, P. F. Treatment for mitochondrial disorders. Cochrane Database.Syst.Rev. 2012;4:CD004426. PubMed
  23. Boos, C. J., White, S. H., Bland, S. A., and McAllister, P. D. Dietary supplements and military operations: caution is advised. J R.Army Med Corps 2010;156(1):41-43. PubMed
  24. Kreider, R. B. Dietary supplements and the promotion of muscle growth with resistance exercise. Sports Med 1999;27(2):97-110. PubMed
  25. Juhn, M. S., O'Kane, J. W., and Vinci, D. M. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am.Diet.Assoc 1999;99(5):593-595.
  26. Volek, J. S., Duncan, N. D., Mazzetti, S. A., Putukian, M., Gomez, A. L., and Kraemer, W. J. No effect of heavy resistance training and creatine supplementation on blood lipids. Int J Sport Nutr.Exerc.Metab 2000;10(2):144-156. PubMed
  27. Robinson, T. M., Sewell, D. A., Casey, A., Steenge, G., and Greenhaff, P. L. Dietary creatine supplementation does not affect some haematological indices, or indices of muscle damage and hepatic and renal function. Br.J Sports Med 2000;34(4):284-288. PubMed
  28. Tarnopolsky, M. A. Potential benefits of creatine monohydrate supplementation in the elderly. Curr.Opin.Clin Nutr.Metab Care 2000;3(6):497-502. PubMed
  29. Tarnopolsky, M. A. and MacLennan, D. P. Creatine monohydrate supplementation enhances high-intensity exercise performance in males and females. Int J Sport Nutr.Exerc.Metab 2000;10(4):452-463. PubMed
  30. Arciero, P. J., Hannibal, N. S., III, Nindl, B. C., Gentile, C. L., Hamed, J., and Vukovich, M. D. Comparison of creatine ingestion and resistance training on energy expenditure and limb blood flow. Metabolism 2001;50(12):1429-1434. PubMed
  31. Chrusch, M. J., Chilibeck, P. D., Chad, K. E., Davison, K. S., and Burke, D. G. Creatine supplementation combined with resistance training in older men. Med Sci.Sports Exerc. 2001;33(12):2111-2117. PubMed
  32. Cox, G., Mujika, I., Tumilty, D., and Burke, L. Acute creatine supplementation and performance during a field test simulating match play in elite female soccer players. Int J Sport Nutr.Exerc.Metab 2002;12(1):33-46. PubMed
  33. Kilduff, L. P., Vidakovic, P., Cooney, G., Twycross-Lewis, R., Amuna, P., Parker, M., Paul, L., and Pitsiladis, Y. P. Effects of creatine on isometric bench-press performance in resistance-trained humans. Med Sci.Sports Exerc. 2002;34(7):1176-1183. PubMed
  34. Brose, A., Parise, G., and Tarnopolsky, M. A. Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults. J Gerontol A Biol.Sci.Med Sci. 2003;58(1):11-19. PubMed
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  36. Tyler, T. F., Nicholas, S. J., Hershman, E. B., Glace, B. W., Mullaney, M. J., and McHugh, M. P. The effect of creatine supplementation on strength recovery after anterior cruciate ligament (ACL) reconstruction: a randomized, placebo-controlled, double-b DOI
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