Maximum Strength Celery Seed Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Maximum Strength Celery Seed Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Maximum Strength Celery Seed Extract is a dietary supplement by Swanson Superior Herbs with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, fluid retention (diuretic), joint pain and inflammation.Based on those ingredients, 651 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Celery seed extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Maximum Strength Celery Seed Extract by Swanson Superior Herbs
Ask about any prescription or over-the-counter medication and we check it for interactions with Maximum Strength Celery Seed Extract by Swanson Superior Herbs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Maximum Strength Celery Seed Extract by Swanson Superior Herbs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: celery seed extract. It's made from the seeds of the celery plant, which have been used traditionally for various purposes.
The supplement also contains microcrystalline cellulose, gelatin, and dicalcium phosphate as inactive ingredients to form and hold the capsule together.
Does it work?
Couldn't assess
The evidence we hold doesn't establish that celery seed extract is effective for sexual dysfunction, anxiety, headache, depression, diabetes, or indigestion — the data rates all of these as having insufficient reliable evidence to judge. That doesn't mean it doesn't work; it means the research available to us hasn't confirmed it yet.
If you're considering this product for a specific health goal, talk it over with your doctor or pharmacist about what the current evidence shows.
How safe is it?
Well-documented data
Orally, celery seed extract is generally well tolerated in most people. The main concerns are photosensitivity (increased sun sensitivity) and allergic reactions, which range from mild — itching or burning in the mouth — to rare but serious ones like anaphylaxis.
Symptoms of celery allergy can include throat swelling, skin reactions, nasal congestion, hives, and in severe cases, difficulty breathing or shock. During pregnancy, medicinal amounts of celery seed are considered likely unsafe because they may affect the uterus — though food amounts are probably fine.
There isn't enough reliable information about celery supplements while breastfeeding, so it's best avoided. If you're pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist before taking this product.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you take blood thinners (anticoagulants or antiplatelet drugs), blood pressure medications, thyroid medication (levothyroxine), psychiatric medications (venlafaxine or others metabolized by CYP1A2), lithium, photosensitizing drugs, or acetaminophen. Moderate and Minor interactions are documented for all of these drug types.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Celery seed extract may be worth considering if you're interested in traditional herbal support — and it's generally well tolerated by most people. However, if you take blood thinners, blood pressure medications, thyroid medication, psychiatric drugs, lithium, or acetaminophen, you need to check with your doctor or pharmacist first because interactions are documented.
Anyone with a known celery allergy should avoid this product. Pregnancy and breastfeeding also call for a conversation with your healthcare provider before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Maximum Strength Celery Seed Extract, straight from the product label.
| Brand | Swanson Superior Herbs |
|---|---|
| Barcode (UPC) | 087614142029 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2018 |
| DSLD ID | 177372 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Maximum Strength Celery Seed Extract by Swanson Superior Herbs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Celery seed extract | 150 mg | -- |
Other ingredients: Microcrystalline Cellulose, Gelatin, Dicalcium Phosphate, May contain one or both of the following
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Standardized Herbal Supplement
Formula
42.5% total phthalides
Seals/Symbols
Guaranteed purity & potency
Precautions
Do not use if seal is broken.
Keep out of reach of children.
Warning: Do not take this product if you are pregnant or nursing. Consult your healthcare provider before use if you are taking prescription medications or have kidney disease.
Storage
Store in a cool, dry place.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take one capsule two times per day with water.
General Statements
To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com
General
SWH202 Rev 1 05 19 17
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Maximum Strength Celery Seed Extract by Swanson Superior Herbs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Maximum Strength Celery Seed Extract by Swanson Superior Herbs
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Celery seed extract
Interacts with651 drugs
Celery is a common vegetable that is also taken as a seed extract or oil supplement, mainly for blood pressure, fluid retention, and joint discomfort....
Celery seed extract monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Gelatin, Dicalcium Phosphate, May contain one or both of the following. These complete the product’s ingredient list but are not active constituents.
Maximum Strength Celery Seed Extract by Swanson Superior Herbs Drug Interactions
HelloPharmacist Interaction Report
Swanson Superior Herbs Maximum Strength Celery Seed Extract has documented interactions with multiple medication types.
The celery seed extract in this product may interact most seriously with blood thinners (anticoagulants/antiplatelet drugs), blood pressure medications, heart and psychiatric drugs, thyroid medication, and some pain relievers — through effects on how your body processes or uses these drugs, or by adding to their effects.
Read the full breakdown — every affected drug type, severity by severity
Moderate interactions are documented with CYP1A2 substrates (a group of drugs your liver metabolizes in a particular way), lithium (a mood stabilizer), levothyroxine (thyroid hormone), venlafaxine (an antidepressant), and blood pressure medications. Celery seed extract may slow how your body clears these drugs or amplify their effects.
In rare cases, people stabilized on levothyroxine have developed low thyroid hormone levels after starting celery seed tablets. There's also a single case report of someone taking celery root extract with venlafaxine and St.
John's wort who experienced mood and cognitive symptoms.
A Minor interaction exists with photosensitizing drugs — celery contains compounds that may increase sun sensitivity. Minor concern also applies to acetaminophen, though the effect hasn't been confirmed in humans.
Before you start this product, run your exact medications through the interaction checker on this page. If you take any blood thinner, blood pressure medication, thyroid medication, antidepressant, lithium, or acetaminophen regularly, check with your doctor or pharmacist first.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Maximum Strength Celery Seed Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Maximum Strength Celery Seed Extract interact with 651 drugs. Click any drug to see the details.
1 of the 1 ingredient in Maximum Strength Celery Seed Extract interact with drugs. Each result below shows which ingredient is responsible. Celery seed extract
Acetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractPhotosensitizing Drugs, Acetaminophen (tylenol, Others) +1 Moderate
Interaction Summary
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, ChlorzoxazoneAcetazone Forte, Extra Strength Tylenol Aches & Strains, Parafon Forte
How Acetaminophen, Chlorzoxazone interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Chlorzoxazone interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dexbrompheniramine, PseudoephedrineSinadrin Plus
How Acetaminophen, Dexbrompheniramine, Pseudoephedrine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Photosensitizing Drugs +1 Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Dexbrompheniramine, Pseudoephedrine interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Dichlorophenazone, Isometheptane interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) +1 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractPhotosensitizing Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Read the full Celery Seed Extract + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, Doxylamine, PseudoephedrineEx Strength Tylenol Sinus Nighttime
How Acetaminophen, Doxylamine, Pseudoephedrine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Doxylamine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +2 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Ibuprofen interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Meperidine interactionAcetaminophen, MethocarbamolRobaxacet
How Acetaminophen, Methocarbamol interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Methocarbamol interactionAcetaminophen, OrphenadrineOrfenagesic
How Acetaminophen, Orphenadrine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Orphenadrine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Oxycodone interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Pentazocine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Maximum Strength Celery Seed Extract — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Phenylephrine, Chlorpheniramine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Maximum Strength Celery Seed Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Celery seed extract
Anticoagulant/Antiplatelet Drugs
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Celery root contains the constituents falcarinol and falcarindiol. Laboratory research suggests that these constituents can inhibit platelet aggregation. This effect has not been reported in humans.
Antihypertensive Drugs
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Clinical research suggests that taking celery seed extract may reduce daytime systolic blood pressure by about 12 mmHg compared to less than 1 mmHg with placebo.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
In vitro and animal research suggests that constituents of celery can inhibit CYP1A2. This effect has not been reported in humans.
Levothyroxine (Synthroid, Others)
Theoretically, celery seed might decrease the effects of levothyroxine.
Several cases of hypothyroidism with low T4 levels have been reported in people who were previously stabilized on levothyroxine and then started taking celery seed tablets. They presented with symptoms such as lethargy, bloating, and dry skin, and recovered when celery seed was stopped. However, celery stem and leaf has been associated with case reports of hyperthyroidism in patients with no pre-existing thyroid disorders.
Lithium
Theoretically, celery might reduce excretion and increase levels of lithium due to potential diuretic effects.
Celery is thought to have diuretic properties. However, this effect has not been confirmed in humans.
Venlafaxine (Effexor)
Theoretically, celery root extract might increase blood levels of venlafaxine.
There is one case report of a patient who experienced medication-induced bipolar disorder after beginning to take celery root extract 1000 mg daily along with venlafaxine 75 mg and St. John's wort 600 mg daily. Symptoms included confusion, speech abnormalities, manic affect, and visual hallucinations. The plasma level of venlafaxine was 476.8 ng/mL (normal range 195-400 ng/mL). It is theorized that celery root increased venlafaxine levels by inhibiting cytochrome P450 2D6.
Acetaminophen (Tylenol, Others)
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Animal research suggests that concomitant use of celery juice plus acetaminophen prolongs the effects of acetaminophen. This effect has been attributed to a decrease in hepatic cytochrome P450 activity. However, other animal research shows that pretreatment with celery root extract protects against acetaminophen-induced acute liver failure. These effects have not been reported in humans.
Photosensitizing Drugs
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Laboratory research shows that celery contains photosensitizing agents such as phenols and psoralens.
Brand information
Manufacturer and brand details for Maximum Strength Celery Seed Extract, from the product label.
Swanson Superior Herbs
See all Swanson Superior Herbs products- Name
- Swanson Health Products
- City
- Fargo
- State
- ND
- ZipCode
- 58104
- Phone Number
- 1-800-437-4148
- Web Address
- www.swansonvitamins.com
Maximum Strength Celery Seed Extract by Swanson Superior Herbs: Common Questions
Does Maximum Strength Celery Seed Extract by Swanson Superior Herbs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on blood thinners?
Will this affect my thyroid medication?
What are the side effects?
Can I take this while pregnant?
Is there enough evidence that this works?
Is this safe to take long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Maximum Strength Celery Seed Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Maximum Strength Celery Seed Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Maximum Strength Celery Seed Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 48 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Celery 48 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Gral N, Beani JC, Bonnot D, et al. [Plasma levels of psoralens after celery ingestion]. Ann Dermatol Venereol 1993;120:599-603.
- Moses, G. Thyroxine interacts with celery seed tablets? Australian Prescriber 2001;24:6-7. DOI
- Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
- Jakovljevic, V., Raskovic, A., Popovic, M., and Sabo, J. The effect of celery and parsley juices on pharmacodynamic activity of drugs involving cytochrome P450 in their metabolism. Eur.J Drug Metab Pharmacokinet. 2002;27(3):153-156. PubMed
- Wang, L., Sterling, B., and Don, P. Berloque dermatitis induced by "Florida water". Cutis 2002;70(1):29-30.
- Weber, I. C., Davis, C. P., and Greeson, D. M. Phytophotodermatitis: the other "lime" disease. J Emerg.Med 1999;17(2):235-237. PubMed
- Rueff, F., Eberlein-Konig, B., and Przybilla, B. Oral hyposensitization with celery juice. Allergy 2001;56(1):82-83. PubMed
- Lombaert, G. A., Siemens, K. H., Pellaers, P., Mankotia, M., and Ng, W. Furanocoumarins in celery and parsnips: method and multiyear Canadian survey. J AOAC Int 2001;84(4):1135-1143. DOI
- Ballmer-Weber, B. K., Hoffmann, A., Wuthrich, B., Luttkopf, D., Pompei, C., Wangorsch, A., Kastner, M., and Vieths, S. Influence of food processing on the allergenicity of celery: DBPCFC with celery spice and cooked celery in patients with celery allergy PubMed
- Hoerler, S. and Ukiwe, J. Laryngeal edema from celery allergic reaction. Am.J.Emerg.Med. 1992;10(6):613. PubMed
- DeLeo, V. A. Photocontact dermatitis. Dermatol Ther 2004;17(4):279-288. PubMed
- Groot, B. J., Belinfante-van Gelder, M. E., and Jans, H. W. [An epidemic of dermatitis caused by blanched celery]. Ned.Tijdschr.Geneeskd. 6-20-1992;136(25):1210-1213.
- Erdmann, S. M., Sachs, B., Schmidt, A., Merk, H. F., Scheiner, O., Moll-Slodowy, S., Sauer, I., Kwiecien, R., Maderegger, B., and Hoffmann-Sommergruber, K. In vitro analysis of birch-pollen-associated food allergy by use of recombinant allergens in the b
- Jeanmougin, M., Varroud-Vial, C., and Dubertret, L. [Phototoxic side-effect following celery ingestion during puvatherapy]. Ann.Dermatol Venereol 2005;132(6-7 Pt 1):566-567.
- Christensen, L. P. and Brandt, K. Bioactive polyacetylenes in food plants of the Apiaceae family: occurrence, bioactivity and analysis. J Pharm.Biomed.Anal. 6-7-2006;41(3):683-693. PubMed
- Gorgus, E., Lohr, C., Raquet, N., Guth, S., and Schrenk, D. Limettin and furocoumarins in beverages containing citrus juices or extracts. Food Chem.Toxicol. 2010;48(1):93-98. PubMed
- Maso, M. J., Ruszkowski, A. M., Bauerle, J., DeLeo, V. A., and Gasparro, F. P. Celery phytophotodermatitis in a chef. Arch.Dermatol. 1991;127(6):912-913. DOI
- Ljunggren, B. Severe phototoxic burn following celery ingestion. Arch.Dermatol. 1990;126(10):1334-1336. DOI
- Held, J. L. Phytophotodermatitis. Am Fam.Physician 1989;39(4):143-146.
- Silverstein, S. R., Frommer, D. A., Dobozin, B., and Rosen, P. Celery-dependent exercise-induced anaphylaxis. J.Emerg.Med. 1986;4(3):195-199. PubMed
- Rose, M. H. and Altman, L. C. Anaphylaxis after ingestion of raw celery. Ann.Allergy 1985;54(2):166.
- Forsbeck, M. and Ros, A. M. Anaphylactoid reaction to celery. Contact Dermatitis 1979;5(3):191. PubMed
- DeChamp, C., Michel, J., Deviller, P., and Perrin, L. F. [Anaphylactic shock to celery and sensitization to ragweed and mugwort. Crossed or concomitant allergy?]. Presse Med. 3-31-1984;13(14):871-874.
- Johansson, S. G., Dannaeus, A., and Lilja, G. The relevance of anti-food antibodies for the diagnosis of food allergy. Ann.Allergy 1984;53(6 Pt 2):665-672.
- Beier, R. C., Ivie, G. W., Oertli, E. H., and Holt, D. L. HPLC analysis of linear furocoumarins (psoralens) in healthy celery (Apium graveolens). Food Chem.Toxicol. 1983;21(2):163-165. PubMed
- Kidd, J. M., III, Cohen, S. H., Sosman, A. J., and Fink, J. N. Food-dependent exercise-induced anaphylaxis. J Allergy Clin Immunol 1983;71(4):407-411. PubMed
- Moneret-Vautrin, D. A. and Kanny, G. [Food-induced anaphylaxis. A new French multicenter survey]. Ann.Gastroenterol Hepatol (Paris) 1995;31(4):256-263.
- Bonnin, J. P., Grezard, P., Colin, L., and Perrot, H. [A very significant case of allergy to celery]. Allerg.Immunol.(Paris) 1995;27(6):209.
- Bonnin, J. P., Grezard, P., Colin, L., and Perrot, H. [A very significant case of allergy to celery cross-reacting with ragweed]. Allerg.Immunol.(Paris) 1995;27(3):91-93.
- Moneret-Vautrin, D. A. and Kanny, G. [Food-induced anaphylaxis. A new French multicenter study]. Bull.Acad.Natl.Med 1995;179(1):161-184.
- Puig, L. and de Moragas, J. M. Enhancement of PUVA phototoxic effects following celery ingestion: cool broth also can burn. Arch.Dermatol. 1994;130(6):809-810. DOI
- Egan, C. L. and Sterling, G. Phytophotodermatitis: a visit to Margaritaville. Cutis 1993;51(1):41-42.
- Boffa, M. J., Gilmour, E., and Ead, R. D. Celery soup causing severe phototoxicity during PUVA therapy. Br.J.Dermatol. 1996;135(2):334.
- Wuthrich, B., Borga, A., and Yman, L. Oral allergy syndrome to a jackfruit (Artocarpus integrifolia). Allergy 1997;52(4):428-431.
- Peterson, S., Lampe, J. W., Bammler, T. K., Gross-Steinmeyer, K., and Eaton, D. L. Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1. Food Chem.Toxicol. 2006;44(9):147 PubMed
- Baek CH, Bae YJ, Cho YS, Moon HB, Kim TB. Food-dependent exercise-induced anaphylaxis in the celery-mugwort-birch-spice syndrome. Allergy. 2010;65(6):792-3. PubMed
- Khalid Z, Osuagwu FC, Shah B, Roy N, Dillon JE, Bradley R. Celery root extract as an inducer of mania induction in a patient on venlafaxine and St John's Wort. Postgrad Med. 2016;128(7):682-3. PubMed
- Palgan K, Götz-Zbikowska M, Tykwinska M, Napiórkowska K, Bartuzi Z. Celery-cause of severe anaphylactic shock. Postepy Hig Med Dosw (Online). 2012;66:132-4.
- Maljaei MB, Moosavian SP, Mirmosayyeb O, Rouhani MH, Namjoo I, Bahreini A. Effect of celery extract on thyroid function; is herbal therapy safe in obesity? Int J Prev Med 2019;10:55. doi: 10.4103/ijpvm.IJPVM_209_17. PubMed
- Rouhi-Boroujeni H, Hosseini M, Gharipour M, Rouhi-Boroujeni H. Is herbal therapy safe in obesity? A case of Apium graveolens (Celery) induced hyperthyroidism. ARYA Atheroscler 2016;12(5):248-9.
- Emad AM, Ali SF, Abdel-Rahman EA, et al. Anti-inflammatory and antioxidant effects of Apium graveolens L. extracts mitigate against fatal acetaminophen-induced acute liver toxicity. J Food Biochem 2020:e13399. Online ahead of print.
- Shayani Rad M, Moohebati M, Mohajeri SA. Effect of celery (Apium graveolens) seed extract on hypertension: A randomized, triple-blind, placebo-controlled, cross-over, clinical trial. Phytother Res 2022.
- Azimi M, Zahedi MJ, Raeiszadeh M, Iraji A, Cramer H, Pasalar M. Efficacy and Safety of a Persian Medicine Formula on Functional Dyspepsia Symptoms: A Randomized Double-Blind Active-Control Clinical Trial. Complement Med Res 2023;30(3):238-247. PubMed
- Ukleja-Sokolowska N, Lis K, Graczyk M, Bartuzi M, Bartuzi Z. The use of inhibition assay in Api g 7 suspected allergy in a female patient with anaphylaxis: A case report. Int J Immunopathol Pharmacol 2024;38:3946320231223004. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC