Microsomal Glucose Oxidase Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Microsomal Glucose Oxidase against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Microsomal Glucose Oxidase is a dietary supplement by Global Healing with 3 active ingredients. Its ingredients are commonly taken for cough and sore throat, wound and burn care, soothing minor skin irritation.Based on those ingredients, 736 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Honey, Raw, Bee Pollen, Raw. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Microsomal Glucose Oxidase by Global Healing
Ask about any prescription or over-the-counter medication and we check it for interactions with Microsomal Glucose Oxidase by Global Healing — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Microsomal Glucose Oxidase by Global Healing
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This liquid contains 3 active ingredients. Raw honey and bee pollen are traditional bee-derived substances used in herbal medicine.
Glucose oxidase is an enzyme. The product also contains several inactive ingredients—glycerin, water, oils (extra virgin olive and avocado), and a mineral preparation—which serve as carriers and preservatives.
Does it work?
Not established
Raw honey is possibly effective for cold sores, cough, mouth sores from cancer treatment (oral mucositis), burns, and dry eye. Bee pollen's effectiveness isn't well established in the data we hold; claims about athletic performance are rated possibly ineffective, while other uses lack sufficient reliable evidence to rate.
The effectiveness of glucose oxidase itself is not documented in our data.
How safe is it?
Well-documented data
Raw honey is generally safe as a food for adults and children over 1 year of age, though you should check with your doctor before using it as a medicine. When taken by mouth, honey is generally well tolerated, but nausea, stomach pain, and vomiting occur in some people.
Topically, burning, pain, and stinging can happen. Honey from the Black Sea coast of Turkey is unsafe—it sometimes contains toxins from rhododendrons that cause heart problems and low blood pressure.
Bee pollen is generally tolerated by most people but can trigger allergic reactions, sometimes severe, especially in those with pollen allergies. Rare serious effects include liver inflammation, kidney problems, and anaphylaxis.
Bee pollen safety during pregnancy is unknown, so it should be avoided; it is also best avoided while breastfeeding. Raw honey is rated likely safe in pregnancy and is considered fine when eaten by a breastfeeding mother, though medicinal use should be discussed with your provider.
Meds to double-check
Moderate interaction found
Talk to your pharmacist before using this product if you take phenytoin (Dilantin) for seizures—honey may raise its levels (Moderate). Blood thinners like warfarin (Coumadin) and other anticoagulant or antiplatelet drugs are a concern with both ingredients (Moderate for bee pollen, Minor for honey).
If you take drugs metabolized by the liver enzyme CYP3A4, check first—honey's effect is unclear.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This product is for people interested in bee-derived supplements for specific conditions like cough or cold sores. If you take anti-seizure medications, blood thinners, or drugs metabolized by your liver, you need to check this with your pharmacist or doctor before starting—interactions are documented.
If you have a history of pollen allergies, be cautious with the bee pollen component.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Microsomal Glucose Oxidase, straight from the product label.
| Brand | Global Healing |
|---|---|
| Barcode (UPC) | 811839032960 |
| Net contents | 2 Fluid Ounce(s); 59.2 Milliliter(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2025 |
| DSLD ID | 339191 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Microsomal Glucose Oxidase by Global Healing, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Honey, Raw | 70 mg | -- |
| Glucose Oxidase | 300 mg | -- |
| Bee Pollen, Raw | 70 mg | -- |
Other ingredients: Glycerin, Water, Structured, Triple-Distilled, Extra Virgin Olive Oil, Extra Virgin Avocado Oil, Ormus Supercharged Minerals
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use Shake bottle well. Take 1 ml daily or as recommended by your healthcare provider.
Formula
Glucose Oxidase (GOD) converts glucose to hydrogen peroxide inside the cell.
Microsomal Glucose Oxidase with Raw Bee Pollen and Raw Honey
General Statements
Discover more
Inspired by Dr. Jana Schmidt
See bottle for best-by date and lot information.
Formulation
Vegan-friendly
Gluten-free Alcohol-free GMO-free Sugar-free
No animal testing
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Microsomal Glucose Oxidase by Global Healing label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Microsomal Glucose Oxidase by Global Healing
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Honey, Raw
Interacts with736 drugs
Honey is a natural food with some real, modest evidence for easing coughs and helping certain wounds, especially when special medical-grade or Manuka...
Honey, Raw monograph & interactionsGlucose Oxidase
Bee Pollen, Raw
Interacts with2 drugs
Bee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most...
Bee Pollen, Raw monograph & interactionsOther (inactive) ingredients: Glycerin, Water, Structured, Triple-Distilled, Extra Virgin Olive Oil, Extra Virgin Avocado Oil, Ormus Supercharged Minerals. These complete the product’s ingredient list but are not active constituents.
Microsomal Glucose Oxidase by Global Healing Drug Interactions
HelloPharmacist Interaction Report
Microsomal Glucose Oxidase by Global Healing contains two active ingredients with documented drug interactions.
Raw honey is the source of the most serious concern: it may increase levels of phenytoin (Dilantin), an anti-seizure medication, which is rated Moderate severity. Additionally, honey has Minor interactions with drugs metabolized by the liver enzyme CYP3A4—research on this is conflicting, with some studies showing honey speeds up their clearance and others showing no effect—and with blood thinners (anticoagulants) and antiplatelet drugs, where honey may theoretically raise bleeding risk.
Read the full breakdown — every affected drug type, severity by severity
Bee pollen carries a Moderate interaction with warfarin (Coumadin), a blood thinner. One case report documented a patient's blood-thinning level doubling after starting bee pollen, raising the risk of bleeding.
We could not check the third ingredient, glucose oxidase, as we hold no interaction data for it.
Altogether, these interactions span 726 individual medications. Use the medication checker below to look up your specific drugs before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Microsomal Glucose Oxidase?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Microsomal Glucose Oxidase interact with 736 drugs. Click any drug to see the details.
2 of the 3 ingredients in Microsomal Glucose Oxidase interact with drugs. Each result below shows which ingredient is responsible. Honey, Raw Bee Pollen, Raw
FosphenytoinCerebyx
How Fosphenytoin interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, honey might increase levels of phenytoin.
Read the full Honey, Raw + Fosphenytoin interactionFosphenytoin SodiumSesquient
How Fosphenytoin Sodium interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, honey might increase levels of phenytoin.
Read the full Honey, Raw + Fosphenytoin Sodium interactionMephenytoinMesantoin
How Mephenytoin interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, honey might increase levels of phenytoin.
Read the full Honey, Raw + Mephenytoin interactionPhenobarbital, PhenytoinDilantin with PB
How Phenobarbital, Phenytoin interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, honey might increase levels of phenytoin.
Read the full Honey, Raw + Phenobarbital, Phenytoin interactionPhenytoinDi-Phen, Dilantin, Dilantin Infatabs, Dilantin injection, Dilantin Kapseals, Phenytek
How Phenytoin interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, honey might increase levels of phenytoin.
Read the full Honey, Raw + Phenytoin interactionWarfarinWarfarin
How Warfarin interacts with Microsomal Glucose Oxidase — through 2 ingredients. Tap an ingredient for the detail:
Bee Pollen, RawWarfarin (coumadin) Moderate
Interaction Summary
There is some concern that bee pollen might interact with warfarin and increase the risk of bleeding.
Read the full Bee Pollen, Raw + Warfarin interactionHoney, RawCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Microsomal Glucose Oxidase — through 2 ingredients. Tap an ingredient for the detail:
Bee Pollen, RawWarfarin (coumadin) Moderate
Interaction Summary
There is some concern that bee pollen might interact with warfarin and increase the risk of bleeding.
Read the full Bee Pollen, Raw + Warfarin Sodium interactionHoney, RawCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Warfarin Sodium interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Honey, Raw + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Honey, Raw + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Honey, Raw + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Honey, Raw + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Honey, Raw + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Microsomal Glucose Oxidase — through 1 ingredient. Tap an ingredient for the detail:
Honey, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey, Raw + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Microsomal Glucose Oxidase with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Honey, Raw
Phenytoin (Dilantin)
Theoretically, honey might increase levels of phenytoin.
In an animal model, the rate and extent of absorption of phenytoin was increased by honey. This effect has not been reported in humans.
Anticoagulant/Antiplatelet Drugs
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro, honey inhibits platelet aggregation and increases the time to clotting. Furthermore, animal research suggests that feeding mice large doses of honey for 12 days increases bleeding time when compared with no intervention. However, these effects have not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Some clinical research shows that honey induces CYP3A4. However, other clinical studies found no effect on CYP3A4 activity. Different honey preparations may have different effects on CYP3A4.
Bee Pollen, Raw
Warfarin (Coumadin)
There is some concern that bee pollen might interact with warfarin and increase the risk of bleeding.
In one case report, a patient on warfarin had a stable international normalized ratio (INR) of 1.9-3.3 for 9 months. The patient's INR was found to be 7.1 after starting bee pollen granules one teaspoon twice daily for approximately one month. The patient's warfarin dose was decreased by approximately 11% in order to return the INR to the therapeutic range while continuing the bee pollen supplement.
Brand information
Manufacturer and brand details for Microsomal Glucose Oxidase, from the product label.
Global Healing
See all Global Healing products- Name
- Global Healing Center, LLC.
- City
- Houston
- State
- TX
- ZipCode
- 77055
- Phone Number
- 1.800.476.0016
- Web Address
- globalhealing.com
Microsomal Glucose Oxidase by Global Healing: Common Questions
Does Microsomal Glucose Oxidase by Global Healing interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is raw honey safe during pregnancy?
What about bee pollen—is it safe when I'm pregnant or breastfeeding?
What are the most common side effects of honey in this product?
Can bee pollen cause serious allergic reactions?
What is this product supposed to do?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Microsomal Glucose Oxidase is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Microsomal Glucose Oxidase’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Honey
Interacts with 736 drugsHoney is a natural food with some real, modest evidence for easing coughs and helping certain wounds, especially when special medical-grade or Manuka honey is used. It is generally safe for...
Read the full Honey monograph → Herb & supplement monographBee Pollen
Interacts with 2 drugsBee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most of these claims is lacking. It can caus...
Read the full Bee Pollen monograph →Sources & How We Checked
Microsomal Glucose Oxidase's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 55 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Honey 40 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Bose B. Honey or sugar in treatment of infected wounds? Lancet 1982;1:963. PubMed
- Ozhan H, Akdemir R, Yazici M, et al. Cardiac emergencies caused by honey ingestion: a single centre experience. Emerg Med J 2004;21:742-4. PubMed
- Centers for Disease Control. Botulism in the Unites Sates, 1899-1996. Handbook for epidemiologists, clinicians, and laboratory workers, 1998. Available online: http://www.cdc.gov/ncidod/dbmd/diseaseinfo/botulism.PDF.
- Simon A, Traynor K, Santos K, et al. Medical honey for wound care - still the 'latest resort'? Evid Based Complement Alternat Med 2009;6:165-73. PubMed
- Gethin G, Cowman S. Case series of use of Manuka honey in leg ulceration. Int Wound J 2005;2:10-15. PubMed
- Ingle R, Levin J, Polinder K. Wound healing with honey - a randomised controlled trial. S Afr Med J 2006;96:831-5.
- Johnson DW, van Eps C, Mudge DW, et al. Randomized, controlled trial of topical exit-site application of honey (Medihoney) versus mupirocin for the prevention of catheter-associated infections in hemodialysis patients. J Am Soc Nephrol 2005;16:1456-62. PubMed
- Sukriti and Garg, S. K. Influence of honey on the pharmacokinetics of phenytoin in rabbits. Ind J Pharmacol 2002;34(147).
- Jung, A. and Ottosson, J. [Infantile botulism caused by honey]. Ugeskr Laeger 2001;163(2):169.
- Gunduz, A., Turedi, S., Uzun, H., and Topbas, M. Mad honey poisoning. Am J Emerg.Med 2006;24(5):595-598.
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