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Dietary supplement

MK-7 Vitamin K2 300 mcg Ingredients & Drug Interactions

by Protocol For Life Balance

Capsule Category: Vitamin
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

MK-7 Vitamin K2 300 mcg is a dietary supplement by Protocol For Life Balance with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of MK-7 Vitamin K2 300 mcg by Protocol For Life Balance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: Vitamin K2, a form of vitamin K at 300 mcg per capsule. The other ingredients — microcrystalline cellulose, hypromellose, and silicon dioxide — are inactive components that help form and stabilize the capsule.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Bone health and vascular elasticity support.
  • We looked for evidence on: Osteoporosis, Cardiovascular disease (CVD), Hemorrhagic disease, Vitamin K-dependent clotting factors deficiency (VKCFD), Warfarin anticoagulation, Bone mineral density — and 2 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Hemorrhagic disease (Natural Medicines).
  • Also on file: Vitamin K is rated "Effective" for Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.

Vitamin K2 is effective for correcting vitamin K-dependent clotting factor deficiency (VKCFD) and hypoprothrombinemia (a blood clotting disorder). It's also shown to be effective in managing the anticoagulation effects of warfarin when clinically appropriate.

For osteoporosis, the evidence is more limited — vitamin K2 is possibly effective, meaning the data suggests a benefit but isn't definitive yet.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When taken by mouth, vitamin K2 is generally well tolerated in healthy people at the amounts in this supplement. The most common side effects are mild: some people experience nausea, diarrhea, stomach upset, or abdominal pain, but these tend to be mild to moderate.

The safety notes remind you that dietary amounts are fine, but it's a good idea to check with your doctor before taking supplements, especially if you have any health conditions.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Blood thinners — especially warfarin (Coumadin) — need a Major-severity check before you start. Vitamin K2 can reduce how well warfarin works at preventing clots.

Talk to your pharmacist or doctor before adding this product if you're on anticoagulation therapy.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This supplement makes sense if you need vitamin K2 for clotting support or are exploring it for bone health — but if you take warfarin or any blood thinner, check with your pharmacist first. Otherwise, it's generally well tolerated.

Your doctor should know you're taking it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MK-7 Vitamin K2 300 mcg, straight from the product label.

Brand Protocol For Life Balance
Barcode (UPC) 707359109940
Net contents 60 Veg Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 326455
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Halal, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MK-7 Vitamin K2 300 mcg by Protocol For Life Balance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veg Capsule(s)
Maximum serving Sizes:
1 Veg Capsule(s)
Servings per container
60
UPC/BARCODE
707359109940
IngredientAmount% DV
Vitamin K2300 mcg--

Other ingredients: Microcrystalline Cellulose, Hypromellose, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Take 1 capsule daily with a meal, or as directed by your healthcare practitioner.

Formula

How it works: Vitamin K is well known for its role in blood clotting, but has also been found to play an important role in normal bone formation and the preservation of bone strength. Vitamin K2 more specifically is a significant regulator of tissue calcification and is critical for the maintenance of arterial elasticity and cardiovascular health. Vitamin K2 includes two of the most studied subtypes. MK-7 (menaquinone-7) and MK-4 (menatetrenone). MK-7, the most readily absorbed and bioactive form of K2, has no common dietary sources. Unlike Vitamin K1, which is stored in the liver, MK-7 is transported directly to tissues and has a longer half-life than either K1 or MK-4.

Halal

MenaQ7 Vitamin K-2 as MK-7

This extra strength product (300 mcg) has more Vitamin K2 than our regular strength product (160 mcg).

Precautions

Cautions/interactions: If you are taking warfarin or other anti-coagulant medications, consult your healthcare practitioner before taking this product.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation

Natural color variation may occur in this product.

Extra strength Supports bone health Supports vascular elasticity

Non-GMO

Vegetarian/vegan

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients.

Seals/Symbols

Halal

FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

MenaQ7 is a registered trademark of NattoPharma ASA, Norway. Patents granted and pending.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

MK-7 Vitamin K2 300 mcg by Protocol For Life Balance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in MK-7 Vitamin K2 300 mcg by Protocol For Life Balance

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veg Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Vitamin K2

Interacts with
2 drugs
300 mcg per serving Form: MenaQ7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

MK-7 Vitamin K2 300 mcg by Protocol For Life Balance Drug Interactions

Want to check YOUR meds against MK-7 Vitamin K2 300 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in MK-7 Vitamin K2 300 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
The maker

Brand information

Manufacturer and brand details for MK-7 Vitamin K2 300 mcg, from the product label.

Protocol For Life Balance

See all Protocol For Life Balance products
Name
Protocol For Life Balance
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
protocolforlife.com
Pharmacist Counseling Corner

MK-7 Vitamin K2 300 mcg by Protocol For Life Balance: Common Questions

Does MK-7 Vitamin K2 300 mcg by Protocol For Life Balance interact with any medications?
Yes. Based on its ingredients, MK-7 Vitamin K2 300 mcg has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
MK-7 Vitamin K2 300 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this interact with my warfarin?
Yes, this is a serious interaction. Vitamin K2 can reduce warfarin's ability to thin your blood, which could affect your clot protection. Don't start this supplement without talking to your doctor — they may need to adjust your warfarin dose or watch you more carefully.
What are the side effects?
When taken by mouth, vitamin K2 is generally well tolerated. The most common side effects are mild and include nausea, diarrhea, stomach upset, and abdominal pain. Serious side effects are very rare.
Is it safe to take during pregnancy or breastfeeding?
Yes, vitamin K2 is rated likely safe during pregnancy and breastfeeding. That said, any supplement decision in pregnancy or lactation should be made with your doctor, who knows your full health picture.
Does this actually work for osteoporosis?
The evidence is not yet conclusive. Vitamin K2 is possibly effective for osteoporosis, meaning research suggests a benefit, but we don't have proof that it prevents fractures or major bone loss. Talk with your doctor about whether it's right for your situation.
What is MK-7?
MK-7 is a form of vitamin K2 — it's one of several types of K2 found in foods like fermented soy and some cheeses. This supplement provides it in a concentrated dose at 300 mcg per capsule.
How many active ingredients are in this?
One — vitamin K2. The rest of the capsule is made of inactive ingredients like cellulose and silica that help hold it together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if MK-7 Vitamin K2 300 mcg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MK-7 Vitamin K2 300 mcg label
Go deeper

The Full Monographs Behind MK-7 Vitamin K2 300 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

MK-7 Vitamin K2 300 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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