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Dietary supplement

Mullein Ingredients & Drug Interactions

by Nature's Answer

Mullein label
See full label image
Liquid Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Mullein against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Mullein is a dietary supplement by Nature's Answer with 1 active ingredient. Its ingredients are commonly taken for cough and chest congestion, sore throat, bronchitis and respiratory irritation.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Mullein leaf (Verbascum thapsus) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Mullein by Nature's Answer

Ask about any prescription or over-the-counter medication and we check it for interactions with Mullein by Nature's Answer — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Mullein by Nature's Answer

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Nature's Answer Mullein is a straightforward product: one active ingredient, mullein leaf extract from Verbascum thapsus. The liquid form also contains purified water, vegetable glycerin, and certified organic alcohol (12–15%) as inactive ingredients to preserve and deliver the extract.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Mullein's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports healthy respiratory function.
  • We looked for evidence on: Asthma, Bronchitis, Cough, Influenza, Pneumonia, chest congestion — and 2 related terms.
  • The closest evidence on file: Mullein is rated "Insufficient Reliable Evidence To Rate" for Bronchitis (Natural Medicines).
  • Also on file: Mullein is rated "Insufficient Reliable Evidence To Rate" for Asthma, Cough, Influenza, Pneumonia.

The evidence we hold on mullein for common uses — cough, bronchitis, asthma, migraine headache, and diarrhea — is insufficient to rate it one way or another. That means studies haven't been solid or plentiful enough yet to say whether it works for these purposes.

If you're considering it for one of these reasons, talk it over with your doctor or pharmacist about what the current evidence suggests and whether it fits your situation.

The evidence, ingredient by ingredient Mullein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mullein is generally well tolerated for short-term use, though human safety data are limited. A small number of case reports have described skin irritation (dermatitis) after direct contact with the whole plant or inhaling plant dust; one person who had this reaction also tested positive to other plants, suggesting possible overlap.

Because there isn't enough data during pregnancy and breastfeeding, the safety information advises against use in these periods. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Mullein

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Mullein.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take a blood thinner or antiplatelet drug (such as warfarin, clopidogrel, or aspirin), double-check with your doctor or pharmacist before adding this product — mullein has a documented mild blood-thinning effect. If you don't take any of these medications, no interactions are documented for the ingredient we checked.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Mullein leaf extract is generally well tolerated, but it does have a mild blood-thinning effect that matters if you take blood thinners or antiplatelet drugs. The evidence for it working on cough, bronchitis, asthma, migraines, or diarrhea isn't established in the data we hold.

If you take a blood thinner or are pregnant or breastfeeding, check with your own doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mullein, straight from the product label.

Brand Nature's Answer
Barcode (UPC) 083000004155
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Feb 25, 2019
DSLD ID 187451
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mullein by Nature's Answer, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
30
UPC/BARCODE
083000004155
IngredientAmount% DV
Mullein leaf (Verbascum thapsus) extract435 mg--

Other ingredients: purified Water, Vegetable Glycerin, 12-15% certified organic Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Gluten Free

K Parve

Bio-Chelated Cold Extraction Process

Formula

K Parve

Verbascum thapsus Made from 1,300mg Mullein Leaves

Low Alcohol

General

9265A Rev. 817

General Statements

Since 1972 Supports healthy respiratory function

Brand IP Statement(s)

Discover Nature's Answer

Our alcohol extracts are produced using our cold Bio-Chelated proprietary extraction process, yielding a Holistically Balanced Advanced Botanical Fingerprint extract in the same synergistic ratios as in the plant.

2017 Nature's Answer

Formulation

Gluten Free

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement take 2 mL (56 drops) three (3) times a day in a small amount of water. Shake well.

Precautions

Keep out of reach of children

Warning: Do not use if pregnant or nursing.

Do not use if safety seal is damaged or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Mullein by Nature's Answer label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Mullein label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Mullein by Nature's Answer

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Mullein leaf (Verbascum thapsus) extract

Interacts with
122 drugs
435 mg per serving

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality huma...

Mullein leaf (Verbascum thapsus) extract monograph & interactions

Other (inactive) ingredients: Purified Water, Vegetable Glycerin, 12-15% certified organic Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mullein by Nature's Answer Drug Interactions

Want to check YOUR meds against Mullein?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Minor

Ingredients driving the most interactions

Mullein leaf (Verbascum thapsus) extract 122

Individual Drug Interactions

The ingredients in Mullein interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Mullein interact with drugs. Each result below shows which ingredient is responsible. Mullein leaf (Verbascum thapsus) extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Mullein with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Mullein leaf (Verbascum thapsus) extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot. This is likely due to at least one of the known constituents of muellein, triterpenoid saponins. However, the effects appear to be mild and results have been inconsistent. Extracts from different plant parts have been show to have varying anticoagulant strengths, with water-based ones being more potent than alcohol-based extracts.

Likelihood Unlikely Evidence A
Mullein leaf (Verbascum thapsus) extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Mullein, from the product label.

Nature's Answer

See all Nature's Answer products
Name
Nature's Answer
Street Address
85 Commerce Drive
City
Hauppauge
State
NY
ZipCode
11788
Phone Number
(800) 439-2324
Web Address
www.naturesanswer.com
Pharmacist Counseling Corner

Mullein by Nature's Answer: Common Questions

Does Mullein by Nature's Answer interact with any medications?
Yes. Based on its ingredients, Mullein has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mullein contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take mullein if I'm on a blood thinner like warfarin or aspirin?
Mullein does have a mild blood-thinning effect of its own, so combining it with a blood thinner or antiplatelet drug could add to that effect. This is documented as a minor interaction, but it's important enough to discuss with your doctor or pharmacist — they can assess your specific dose and situation and advise whether it's okay to use together or if you should skip it.
Is mullein safe during pregnancy or breastfeeding?
No — there isn't enough safety data to recommend it during either pregnancy or breastfeeding, so it's best avoided in both periods. Talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or breastfeeding and interested in mullein.
What can mullein actually help with?
The evidence we hold on mullein for cough, bronchitis, asthma, migraine headache, and diarrhea is insufficient to rate — meaning studies haven't been solid or complete enough to say whether it works for these uses. Your doctor or pharmacist can discuss what the current research suggests and whether it makes sense for your situation.
Are there any side effects from mullein?
Mullein is generally well tolerated for short-term use. A small number of case reports have described skin irritation after direct contact with the whole plant or inhaling plant dust. Human safety data are limited overall, so if you use it and notice any unusual symptoms, let your doctor or pharmacist know.
What is mullein leaf extract used for?
Mullein has a traditional history of use for respiratory and digestive complaints, though the scientific evidence on how well it works isn't established in the data we hold. Your doctor or pharmacist can tell you more about whether it might be right for what you're dealing with.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mullein label
Go deeper

The Full Monographs Behind Mullein’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Mullein

Interacts with 122 drugs

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality human studies are lacking, so its benefits a...

Read the full Mullein monograph →
Sources

Sources & How We Checked

Mullein's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mullein 2 references
  1. Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
  2. Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.

See these in context on the Mullein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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