Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Multi Collagen Ingredients & Drug Interactions

by Codeage

Multi Collagen label
See full label image
Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Multi Collagen against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Multi Collagen is a dietary supplement by Codeage with 6 active ingredients. Its ingredients are commonly taken for skin health and wrinkles, joint pain and osteoarthritis, bone health.Based on those ingredients, 1,430 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Ashwagandha root extract, organic Amla berry powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Multi Collagen by Codeage

Ask about any prescription or over-the-counter medication and we check it for interactions with Multi Collagen by Codeage — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Multi Collagen by Codeage

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Multi Collagen Protein Complex” is a proprietary blend — the label gives one combined amount (2,000.10 mg) without saying how much of each component you get.

This capsule contains 6 active ingredients. The collagen content comes from three sources: hydrolyzed bovine collagen peptides, eggshell membrane collagen, and hydrolyzed collagen — all forms of the structural protein your body uses in skin, joints, and connective tissue.

You also get chicken bone broth, which is a traditional source of collagen and amino acids. The formula rounds out with organic ashwagandha root extract (an adaptogen herb traditionally used for stress and sleep) and organic amla berry powder (also called Indian gooseberry, a vitamin C-rich fruit).

The capsule itself is made from methylcellulose.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Joint and bone health with skin and hair support.
  • We looked for evidence on: Joint pain, Osteoarthritis, Brittle nails, Aging skin, Exercise-induced muscle damage, Exercise-induced muscle soreness — and 3 related terms.
  • The strongest evidence on file: Collagen Peptides is rated "Possibly Effective" for Aging skin (Natural Medicines).
  • Also on file: Eggshell Membrane is rated "Possibly Effective" for Osteoarthritis.
  • Also on file: Collagen Peptides is rated "Possibly Ineffective" for Muscle strength.

For aging skin, the hydrolyzed bovine collagen peptides are rated possibly effective — some evidence backs their use, though more research would help confirm the benefit. Eggshell membrane collagen is possibly effective for osteoarthritis.

Ashwagandha is possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder. Amla berry is possibly effective for acid reflux (GERD) and high cholesterol.

For muscle strength, the collagen peptides are rated possibly ineffective, and eggshell membrane has insufficient evidence. Acne, athletic performance, joint pain, and skin aging (from eggshell membrane alone) don't have enough reliable evidence to rate.

Ashwagandha for bipolar disorder and amla berry for hair loss also lack sufficient data in our records.

The evidence, ingredient by ingredient Collagen Peptides Eggshell Membrane Ashwagandha Indian Gooseberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hydrolyzed bovine collagen peptides are generally well tolerated as a dietary protein, though nausea, upset stomach, diarrhea, and gas are rare but possible. However, it's not well studied in pregnancy, so check with your doctor before using if you're pregnant; little safety data exists during breastfeeding, so caution is advised.

Eggshell membrane collagen is generally well tolerated in short-term studies but must be avoided by anyone allergic to eggs. The safety data advises against it during pregnancy and breastfeeding.

Ashwagandha is generally well tolerated short-term in healthy adults, but long-term and quality safety data are limited. Most common side effects — diarrhea, upset stomach, nausea, vomiting — are uncommon at typical doses.

Rare serious reports include acute hepatitis and liver failure; one case describes intracranial bleeding and blood vessel constriction. The safety data advises against ashwagandha in pregnancy (traditionally thought to risk miscarriage) and breastfeeding.

Amla berry is generally well tolerated as a food, though supplement safety is less studied. A small number of trial participants reported epigastric discomfort, fatigue, or musculoskeletal pain.

The safety data advises against it in pregnancy and breastfeeding due to insufficient data.

Side effects, ingredient by ingredient Collagen Peptides Eggshell Membrane Ashwagandha Indian Gooseberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 4 matched ingredients can interact with medications — Indian Gooseberry, Ashwagandha.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,431 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any sedatives, sleeping pills, or anti-anxiety medications (including benzodiazepines like Valium or Xanax), blood pressure medications, diabetes medications, blood thinners (anticoagulants) or aspirin-type drugs, thyroid hormones, immunosuppressants, or medications that stress your liver, talk with your doctor or pharmacist before taking this product. Ashwagandha and amla berry each carry Moderate interactions with several of these drug types.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines collagen from multiple sources with ashwagandha and amla berry — ingredients with some evidence for aging skin, joint health, stress, sleep, acid reflux, and cholesterol. If you don't take sedatives, blood pressure or diabetes drugs, blood thinners, benzodiazepines, thyroid hormones, immunosuppressants, or liver-stressing medications, and you're not pregnant or breastfeeding, it's worth discussing with your doctor or pharmacist.

Those on any of the medications mentioned above should check with their own healthcare provider before starting, since the interactions could be significant.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Multi Collagen, straight from the product label.

Brand Codeage
Barcode (UPC) X001M1WBIV
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 269366
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Multi Collagen by Codeage, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
X001M1WBIV
IngredientAmount% DV
hydrolyzed Bovine Collagen Peptides0 NP--
Multi Collagen Protein Complex2000.1 mg--
Eggshell Membrane Collagen0 NP--
Chicken Bone Broth0 NP--
organic Ashwagandha root extract0 NP--
Collagen, Hydrolyzed0 NP--
organic Amla berry powder0 NP--

Other ingredients: Methylcellulose Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

5 Types collagen

Type l, ll, lll, V & X

Formulation

Grass-fed + Pastured raised

Non GMO

Hydrolyzed

Contains no filler ingredients, artificial flavors, colors, sweeteners or preservatives.

Seals/Symbols

cGMP Certified

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Adults take 3 capsules daily with 8 ounces of water or your favorite beverage. May be taken with or without food.

Brand IP Statement(s)

Copyright Codeage LLC. All rights reserved.

Precautions

Contains: Fish (Cod, Snapper), Egg.

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Please use caution if you have allergies or sensitivities to any of the listed ingredients. This product is manufactured in a facility that processes fish and tree nuts. Allergen warning: Fish (Cod, Snapper), Egg.

Notice: Use this product as a food supplement only. Do not use for weight reduction.

Do not use if product has been opened or tampered with in any way. Keep out of reach of children and pets.

Keep out of reach of children and pets.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Multi Collagen by Codeage label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Multi Collagen label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Multi Collagen by Codeage

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Multi Collagen Protein Complex

2000.1 mg per serving

Other (inactive) ingredients: Methylcellulose Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Multi Collagen by Codeage Drug Interactions

Want to check YOUR meds against Multi Collagen?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,430Drugs
1,002 Moderate 428 Minor

Ingredients driving the most interactions

organic Ashwagandha root extract 1,372
organic Amla berry powder 208

Individual Drug Interactions

The ingredients in Multi Collagen interact with 1,430 drugs. Click any drug to see the details.

2 of the 6 ingredients in Multi Collagen interact with drugs. Each result below shows which ingredient is responsible. organic Ashwagandha root extract organic Amla berry powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Multi Collagen with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Ashwagandha root extract10 drug types · 1,372 drugs

Antidiabetes Drugs

Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.

Likelihood Possible Evidence D
Thyroid Hormone

Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Serotonergic Drugs

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]

Likelihood Possible Evidence C
organic Ashwagandha root extract full monograph & interactions

organic Amla berry powder4 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking Indian gooseberry 500 mg along with clopidogrel 75 mg or ecosprin 75 mg, as a single dose or for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg or ecosprin 75 mg alone. Until more is known, use caution when taking Indian gooseberry in combination with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking Indian gooseberry fruit or fruit extract alone or in conjunction with antidiabetes medications can lower blood glucose levels. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Aspirin

Theoretically, Indian gooseberry may increase the risk of bleeding if used with aspirin; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with ecosprin 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus ecosprin 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with ecosprin 75 mg alone.

Likelihood Possible Evidence B
Clopidogrel (Plavix)

Theoretically, Indian gooseberry may increase the risk of bleeding if used with clopidogrel; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with clopidogrel 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus clopidogrel 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg alone.

Likelihood Possible Evidence B
organic Amla berry powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Multi Collagen, from the product label.

Codeage

See all Codeage products
Name
Codeage LLC
Street Address
449 S. Beverly Dr.
City
Beverly Hills
State
CA
ZipCode
90212
Web Address
www.codeage.com
Pharmacist Counseling Corner

Multi Collagen by Codeage: Common Questions

Does Multi Collagen by Codeage interact with any medications?
Yes. Based on its ingredients, Multi Collagen has a known interaction with 1,430 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Multi Collagen contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy?
No. The safety data advises against both ashwagandha (traditionally thought to risk miscarriage) and eggshell membrane during pregnancy. Hydrolyzed bovine collagen is not well studied in pregnancy either. Talk with your doctor before using if you're pregnant or planning to become pregnant.
Is this safe while breastfeeding?
The safety data advises against ashwagandha and amla berry, and advises caution with hydrolyzed bovine collagen and eggshell membrane, during breastfeeding due to insufficient data. Check with your doctor or pharmacist for personalized advice.
Does collagen really help with wrinkles and aging skin?
The hydrolyzed bovine collagen in this product is rated possibly effective for aging skin and dry skin, meaning there's some evidence, but more research would strengthen confidence in the benefit.
What does ashwagandha do in this product?
Ashwagandha is possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder. It's included as an adaptogen herb to help with relaxation and sleep quality.
What's amla berry for?
Amla berry (Indian gooseberry) is possibly effective for acid reflux and high cholesterol. It's a vitamin C-rich fruit traditionally used to support digestive and metabolic health.
Can I take this if I'm on a blood thinner like warfarin?
No, not without checking with your doctor first. The amla berry in this product may increase bleeding risk when used with blood thinners or aspirin-type drugs. Your doctor or pharmacist needs to review it for your specific situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Multi Collagen label
Go deeper

The Full Monographs Behind Multi Collagen’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Collagen Peptides

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is still developing and results vary. They...

Read the full Collagen Peptides monograph → Herb & supplement monograph

Eggshell Membrane

Eggshell membrane is a natural source of collagen, hyaluronic acid, and other connective-tissue compounds that is marketed mainly for joint comfort and osteoarthritis. Some small studies sug...

Read the full Eggshell Membrane monograph → Herb & supplement monograph

Ashwagandha

Interacts with 1,372 drugs

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...

Read the full Ashwagandha monograph → Herb & supplement monograph

Indian Gooseberry

Interacts with 208 drugs

Indian gooseberry (amla) is a vitamin C-rich fruit used in Ayurvedic medicine for many purposes, from antioxidant support to cholesterol and digestion. Early research is promising for some u...

Read the full Indian Gooseberry monograph →
Sources

Sources & How We Checked

Multi Collagen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 43 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Collagen Peptides 2 references
  1. Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
  2. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed

See these in context on the Collagen Peptides monograph →

Eggshell Membrane 3 references
  1. Osteoarthritis — MedlinePlus (NIH) Source
  2. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  3. Using Dietary Supplements Wisely — NIH NCCIH Source

See these in context on the Eggshell Membrane monograph →

Ashwagandha 32 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Upton R, ed. Ashwagandha Root (Withania somnifera): Analytical, quality control, and therapuetic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia 2000:1-25.
  3. Davis L, Kuttan G. Effect of Withania somnifera on cyclophosphamide-induced urotoxicity. Cancer Lett 2000;148:9-17. PubMed
  4. Davis L, Kuttan G. Suppressive effect of cyclophosphamide-induced toxicity by Withania somnifera extract in mice. J Ethnopharmacol 1998;62:209-14. PubMed
  5. Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 2000;5:334-46. DOI
  6. Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root. Indian J Exp Biol 2000;38:607-9.
  7. Kulkarni RR, Patki PS, Jog VP, et al. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33:91-5. PubMed
  8. Ahumada F, Aspee F, Wikman G, Hancke J. Withania somnifera exract. Its effects on arterial blood pressure in anaesthetized dogs. Phytother Res 1991;5:111-14.
  9. Panda S, Kar A. Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice. J Ethnopharmacol 1999;67:233-39. PubMed
  10. Panda S, Kar A. Changes in thyroid hormone concentrations after administration of ashwagandha root extract to adult male mice. J Pharm Pharmacol 1998;50:1065-68. PubMed
  11. Sehgal, V. N., Verma, P., and Bhattacharya, S. N. Fixed-drug eruption caused by ashwagandha (Withania somnifera): a widely used Ayurvedic drug. Skinmed. 2012;10(1):48-49.
  12. Agnihotri AP, Sontakke SD, Thawani VR, Saoji A, Goswami VS. Effects of Withania somnifera in patients of schizophrenia: a randomized, double blind, placebo controlled pilot trial study. Indian J Pharmacol. 2013;45(4):417-8. PubMed
  13. Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KI. Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients. Integr Cancer Ther. 2013;12(4):312-22.
  14. Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed
  15. Durg S, Bavage S, Shivaram SB. Withania somnifera (Indian ginseng) in diabetes mellitus: A systematic review and meta-analysis of scientific evidence from experimental research to clinical application. Phytother Res. 2020;34(5):1041-1059.
  16. Björnsson HK, Björnsson ES, Avula B, et al. Ashwagandha-induced liver injury: A case series from Iceland and the US Drug-Induced Liver Injury Network. Liver Int. 2020;40(4):825-829. PubMed
  17. Tharakan A, Shukla H, Benny IR, Tharakan M, George L, Koshy S. Immunomodulatory Effect of Withania somnifera (Ashwagandha) Extract-A Randomized, Double-Blind, Placebo Controlled Trial with an Open Label Extension on Healthy Participants. J Clin Med 2021;1 PubMed
  18. Ireland PJ, Hardy T, Burt AD, Donnelly MC. Drug-induced hepatocellular injury due to herbal supplement ashwagandha. J R Coll Physicians Edinb. 2021;51(4):363-365. PubMed
  19. Kamal HI, Patel K, Brdak A, Heffernan J, Ahmad N. Ashwagandha as a unique cause of thyrotoxicosis presenting with supraventricular tachycardia. Cureus. 2022 Mar 25;14(3):e23494. PubMed
  20. Suryawanshi G, Abdallah M, Thomson M, Desai N, Chauhan A, Lim N. Ashwagandha-Associated Acute Liver Failure Requiring Liver Transplantation. Am J Ther 2023;30(1):e80-e83. PubMed
  21. Pusec CM, Wolsky R, Llerena C, Sura P. A Case of Supplement-Induced Hepatitis. Cureus 2022;14(10):e30433. PubMed
  22. Ajgaonkar A, Jain M, Debnath K. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract for Improvement of Sexual Health in Healthy Women: A Prospective, Randomized, Placebo-Controlled Study. Cureus 2022;14(10):e30787. PubMed
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See these in context on the Ashwagandha monograph →

Indian Gooseberry 6 references
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See these in context on the Indian Gooseberry monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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