Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

NitroVasc Boost Berry Flavor Ingredients & Drug Interactions

by Life Extension

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

NitroVasc Boost Berry Flavor is a dietary supplement by Life Extension with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, heart and blood vessel health, blood pressure support.Based on those ingredients, 811 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Aronia. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of NitroVasc Boost Berry Flavor by Life Extension

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

NitroVasc Boost is a 2-ingredient powder. The active components are inositol-stabilized arginine silicate and aronia (chokeberry), a dark purple berry.

The powder also contains inactive ingredients: berry flavor, citric acid, silica, and stevia.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Chokeberry's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: nitric oxide production and vascular health.
  • We looked for evidence on: Cardiovascular disease (CVD), Hypertension, endothelial function, vasodilation, circulatory health.
  • The closest evidence on file: Chokeberry is rated "Possibly Ineffective" for Cardiovascular disease (CVD) (Natural Medicines).
  • Also on file: Chokeberry is rated "Insufficient Reliable Evidence To Rate" for Hypertension.

The evidence for aronia in this product is thin. For heart disease (cardiovascular disease), the data suggests it's possibly ineffective.

For age-related cognitive decline, age-related macular degeneration (AMD), athletic performance, and cancer, there isn't enough reliable evidence to rate whether it works. We hold no effectiveness data for inositol-stabilized arginine silicate.

The evidence, ingredient by ingredient Chokeberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chokeberry is generally well tolerated as a food, but safety of concentrated supplements hasn't been well studied, so use caution with supplement amounts. The most common side effects from chokeberry are constipation, diarrhea, nausea, stomach cramps, and vomiting.

In one small trial, about 14% of people reported these gastrointestinal issues at lower doses, and in another, about 53% reported them at higher doses over 6 weeks. For lactation, safety data isn't on file — talk with your doctor or pharmacist about whether this product is right for you if you're breastfeeding.

Side effects, ingredient by ingredient Chokeberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chokeberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 812 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking NitroVasc Boost, check with your doctor or pharmacist if you take trabectedin (a cancer drug), blood thinners or antiplatelet drugs like warfarin or aspirin, or diabetes medications that lower blood sugar. Chokeberry may affect how your body processes dozens of other common drugs through liver enzyme inhibition, so confirm your full medication list is safe with it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

NitroVasc Boost contains ingredients with unclear effectiveness for heart health or cognitive function, but aronia carries moderate interaction risks — especially with cancer drugs, blood thinners, and diabetes medicine. If you take any of those or have frequent gastrointestinal issues, discuss this product with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about NitroVasc Boost Berry Flavor, straight from the product label.

Brand Life Extension
Barcode (UPC) 737870232032
Net contents 30 Stick Pack(s); 94.2 Gram(s); 3.32 Oz(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 232772
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for NitroVasc Boost Berry Flavor by Life Extension, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3.14 Gram(s)
Maximum serving Sizes:
3.14 Gram(s)
UPC/BARCODE
737870232032
IngredientAmount% DV
Inositol-stabilized Arginine Silicate1500 mg--
Aronia500 mg--

Other ingredients: Berry flavor, Citric Acid, Silica, Stevia

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

NitroVasc Boost combines an innovative source of arginine with polyphenols from the aronia berry to promote healthy vasodilation and circulatory health. This tasty drink mix encourages endothelial nitric oxide (NO) production in your vascular endothelium, the delicate inner lining of your blood vessels that is responsible for the healthy function of your vital arteries and veins.

Suggested/Recommended/Usage/Directions

Read the entire label and follow the directions carefully prior to use. Directions: Mix one (1) stick pack in 8 oz of water. Drink on an empty stomach, or as recommended by a healthcare practitioner.

Precautions

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Brand IP Statement(s)

Nitrosigine is a registered trademark of Nutrition 21, LLC. Nitrosigine is patent protected.

Seals/Symbols

Non GMO LE Certified

Formulation

Non GMO LE Certified

Support for nitric oxide production and vascular health

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

NitroVasc Boost Berry Flavor by Life Extension label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in NitroVasc Boost Berry Flavor by Life Extension

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size3.14 Gram(s) Dosage formPowder Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Inositol-stabilized Arginine Silicate

1500 mg per serving

Aronia

Interacts with
811 drugs
500 mg per serving Form: total Polyphenols

Chokeberry (aronia) is a dark berry rich in antioxidants called polyphenols, and it's widely eaten as juice, jam, and supplements. Early research hint...

Aronia monograph & interactions

Other (inactive) ingredients: Berry flavor, Citric Acid, Silica, Stevia. These complete the product’s ingredient list but are not active constituents.

Interaction report

NitroVasc Boost Berry Flavor by Life Extension Drug Interactions

Want to check YOUR meds against NitroVasc Boost Berry Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
811Drugs
811 Moderate

Ingredients driving the most interactions

Aronia 811

Each ingredient & the kinds of drugs it affects

For each ingredient in NitroVasc Boost Berry Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Aronia4 drug types · 811 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Clinical and in vitro research suggests that chokeberry extract can temporarily inhibit platelet aggregation and decrease clot formation.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, chokeberry might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Some clinical research shows that chokeberry decreases levels of blood glucose in some patients with diabetes. However, other clinical research suggests that chokeberry has no significant effect on blood glucose levels.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that chokeberry inhibits CYP3A4. In humans, there is one case report of a drug interaction with trabectedin, a CYP3A4 substrate, which is hypothesized to have been caused by chokeberry inhibition of CYP3A4.

Likelihood Possible Evidence D
Trabectedin (Yondelis)

Theoretically, chokeberry might increase the effects and adverse effects of trabectedin.
In one case report, a patient drinking chokeberry juice developed rhabdomyolysis induced by trabectedin, a cytochrome P450 3A4 (CYP3A4) substrate. It is possible that inhibition of CYP3A4 by chokeberry juice might have inhibited the metabolism of trabectedin and increased trabectedin levels in this patient.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for NitroVasc Boost Berry Flavor, from the product label.

Life Extension

See all Life Extension products
Name
Quality Supplements and Vitamins, Inc.
City
Ft. Lauderdale
State
FL
ZipCode
33309
Phone Number
1-866-280-2852
Web Address
LifeExtension.com
Pharmacist Counseling Corner

NitroVasc Boost Berry Flavor by Life Extension: Common Questions

Does NitroVasc Boost Berry Flavor by Life Extension interact with any medications?
Yes. Based on its ingredients, NitroVasc Boost Berry Flavor has a known interaction with 811 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
NitroVasc Boost Berry Flavor contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does aronia actually help with heart health or circulation?
The research suggests aronia is possibly ineffective for heart disease prevention or management. For other claims like cognitive decline or eye health, there isn't enough reliable evidence yet to say whether it works.
What are the most common side effects?
Constipation, diarrhea, nausea, stomach cramps, and vomiting are the main ones reported. In small trials, gastrointestinal side effects showed up in roughly 14% to 53% of people depending on the dose, so stomach upset is fairly common.
Is this safe to take long-term?
Chokeberry is well tolerated as a food, but safety data for concentrated supplement amounts over the long term isn't well established. Use caution and talk with your pharmacist about your individual situation.
Can I take this while breastfeeding?
We don't have safety information on file for aronia during lactation. Talk with your doctor or pharmacist — they can help you decide what's right for you and your baby.
What does inositol-stabilized arginine silicate do?
We hold no effectiveness or interaction data for this ingredient, so we can't tell you what role it plays in this product. Your pharmacist may have additional information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if NitroVasc Boost Berry Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

NitroVasc Boost Berry Flavor label
Go deeper

The Full Monographs Behind NitroVasc Boost Berry Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

NitroVasc Boost Berry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chokeberry 8 references
  1. Sikora J, Broncel M, Markowicz M, Chalubinski M, Wojdan K, Mikiciuk-Olasik E. Short-term supplementation with Aronia melanocarpa extract improves platelet aggregation, clotting, and fibrinolysis in patients with metabolic syndrome. Eur J Nutr. 2012 Aug;51 PubMed
  2. Simeonov SB, Botushanov NP, Karahanian EB, Pavlova MB, Husianitis HK, Troev DM. Effects of Aronia melanocarpa juice as part of the dietary regimen in patients with diabetes mellitus. Folia Med (Plovdiv). 2002;44(3):20-3.
  3. Savikin K, Menkovic N, Zdunic G, Pljevljakusic D, Spasic S, Kardum N, Konic-Ristic A. Dietary supplementation with polyphenol-rich chokeberry juice improves skin morphology in cellulite. J Med Food. 2014 May;17(5):582-7. PubMed
  4. Bräunlich M, Christensen H, Johannesen S, Slimestad R, Wangensteen H, Malterud KE, Barsett H. In vitro inhibition of cytochrome P450 3A4 by Aronia melanocarpa constituents. Planta Med. 2013 Jan;79(2):137-41. PubMed
  5. Strippoli S, Lorusso V, Albano A, Guida M. Herbal-drug interaction induced rhabdomyolysis in a liposarcoma patient receiving trabectedin. BMC Complement Altern Med. 2013 Jul 30;13:199. PubMed
  6. Ryszawa N, Kawczynska-Drózdz A, Pryjma J, Czesnikiewicz-Guzik M, Adamek-Guzik T, Naruszewicz M, Korbut R, Guzik TJ. Effects of novel plant antioxidants on platelet superoxide production and aggregation in atherosclerosis. J Physiol Pharmacol. 2006 Dec;57(
  7. Milutinovic M, Velickovic Radovanovic R, Savikin K, et al. Chokeberry juice supplementation in type 2 diabetic patients - impact on health status. J Appl Biomed 2019;17(4):218-224. PubMed
  8. Lackner S, Sconocchia T, Ziegler T, et al. Immunomodulatory effects of aronia juice polyphenols-results of a randomized placebo-controlled human intervention study and cell culture experiments. Antioxidants (Basel) 2022;11(7):1283. PubMed

See these in context on the Chokeberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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