No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

NutraFlora FOS Powder Ingredients & Drug Interactions

by The Vitamin Shoppe

Powder Category: Fiber And Other Nutrients
No known interaction
The interaction bottom line No known interaction

NutraFlora FOS Powder is a dietary supplement by The Vitamin Shoppe with 1 active ingredient. Its ingredients are commonly taken for digestive and gut health, prebiotic to support good bacteria, constipation relief.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of NutraFlora FOS Powder by The Vitamin Shoppe

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product has one active ingredient: NutraFlora FOS, a type of fructo-oligosaccharide. FOS are short-chain carbohydrates that act as a prebiotic — they're meant to feed the good bacteria in your gut.

The product contains no inactive ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Fructo-oligosaccharides (fos)'s own graded uses on its monograph.

Why this rating?
  • The label markets this product for: prebiotic to nourish probiotics and digestive health.
  • We looked for evidence on: Constipation, Travelers' diarrhea, Gut microbiota, Intestinal health, Dysbiosis.
  • The closest evidence on file: Fructo-oligosaccharides (fos) is rated "Insufficient Reliable Evidence To Rate" for Constipation (Natural Medicines).
  • Also on file: Fructo-oligosaccharides (fos) is rated "Insufficient Reliable Evidence To Rate" for Travelers' diarrhea.

The evidence we hold on FOS doesn't establish that it works for osteoporosis, constipation, diabetes, travelers' diarrhea, or high cholesterol. For each of these uses, the data shows insufficient reliable evidence to rate it.

If you're considering FOS for one of these reasons, talk with your pharmacist or doctor about what the current research actually supports.

The evidence, ingredient by ingredient Fructo-oligosaccharides (fos)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

FOS are generally well tolerated, especially at the amounts you'd eat in food. At supplement-level doses, though, the safety data is limited, so it's worth checking with your doctor before starting.

The most common side effects are abdominal pain, bloating, and gas — especially at higher doses. Interestingly, a review of eight small studies found that FOS at doses of 2.5 to 15 grams daily for up to 8 weeks didn't actually increase these symptoms any more than placebo did, though some people do experience them.

Side effects, ingredient by ingredient Fructo-oligosaccharides (fos)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Run your exact medications through the checker on this page to be thorough.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

If you're interested in supporting your gut bacteria with a prebiotic, FOS is generally well tolerated and has no documented medication interactions. Just be aware that the evidence for specific health claims is weak, and start with a lower dose to see how your digestion handles it.

Talk with your pharmacist if you have ongoing bloating or gas, or if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about NutraFlora FOS Powder, straight from the product label.

Brand The Vitamin Shoppe
Barcode (UPC) 766536021529
Net contents 4 oz.; 113 Gram(s)
Market status On market
Date entered into DSLD Jul 25, 2014
DSLD ID 35868
Product type Fiber And Other Nutrients
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for NutraFlora FOS Powder by The Vitamin Shoppe, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 tsp
Maximum serving Sizes:
1 tsp
Servings per container
28
UPC/BARCODE
766536021529
IngredientAmount% DV
NutraFlora(R) FOS4 Gram(s)--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

specialty

prebiotic to nourish probiotics in your body digestive health

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

{QRC} learn more at vsquality.net

FDA Statement of Identity

dietary supplement

Formulation

gluten free dairy free soy free nut free

Does not contain: Yeast, Corn, Wheat, Gluten, Salt, Soy, Dairy, Citrus, Fish, Preservatives, Artificial Colors or Flavors.

Seals/Symbols

V SUITABLE FOR MOST VEGETARIANS

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

DIRECTIONS: As a dietary supplement, take one (1) teaspoon daily. NutraFlora(R) mixes easily with water or your favorite beverage.

Precautions

WARNING: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

KEEP OUT OF REACH OF CHILDREN.

TAMPER EVIDENT Do not use if outer seal is broken or missing.

Storage

STORE IN A COOL, DRY PLACE.

General

Item No. VS-2152 1075603 DO 1

Brand IP Statement(s)

Nutraflora(R) is a registered trademark of Golden Technologies Company, Inc.

See for yourself

NutraFlora FOS Powder by The Vitamin Shoppe label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in NutraFlora FOS Powder by The Vitamin Shoppe

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 tsp Dosage formPowder Servings per container28 Amounts shown are per serving.

NutraFlora(R) FOS

No known
interactions
4 Gram(s) per serving Form: Fructo-Oligosaccharides

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are gener...

NutraFlora(R) FOS monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

NutraFlora FOS Powder by The Vitamin Shoppe Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in NutraFlora FOS Powder. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for NutraFlora FOS Powder, from the product label.

The Vitamin Shoppe

See all The Vitamin Shoppe products
Name
Vitamin Shoppe, Inc.
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-800-223-1216
Web Address
www.vitaminshoppe.com
Pharmacist Counseling Corner

NutraFlora FOS Powder by The Vitamin Shoppe: Common Questions

Does NutraFlora FOS Powder by The Vitamin Shoppe interact with any medications?
We do not currently list a known interaction for the mapped ingredients in NutraFlora FOS Powder. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
NutraFlora FOS Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will FOS give me gas or bloating?
It can, especially when you first start or at higher doses. The most common side effects are gas, bloating, and abdominal pain. Interestingly, when researchers tested FOS at 2.5 to 15 grams daily in clinical trials, it didn't cause these symptoms any more often than placebo did — so your experience may vary. Starting with a lower dose can help.
Is FOS safe if I'm pregnant or breastfeeding?
The safety data we hold doesn't include pregnancy and lactation information for FOS. There isn't enough data to know either way, so talk with your doctor or pharmacist for personalized advice.
Does FOS actually help with constipation or cholesterol?
The evidence we hold shows insufficient reliable evidence to rate FOS for constipation, high cholesterol, diabetes, or osteoporosis. If you're looking to use it for one of these reasons, chat with your pharmacist about what research actually supports.
What is FOS and why would I take it?
FOS is a prebiotic — a type of carbohydrate that feeds the good bacteria in your gut. The idea is that a healthier gut microbiome may support digestion and overall health, though the evidence for specific claims is still limited.
Can I take this with my other medications?
No interactions are documented in our data for FOS. That said, it's always smart to run your exact medications through the checker on this page before you start anything new.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if NutraFlora FOS Powder is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

NutraFlora FOS Powder label
Sources

Sources & How We Checked

NutraFlora FOS Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fructo-oligosaccharides (fos) 6 references
  1. Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
  2. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
  5. Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
  6. Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed

See these in context on the Fructo-oligosaccharides (fos) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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