Omega-3 Phospholipids Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Omega-3 Phospholipids against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Omega-3 Phospholipids is a dietary supplement by Nordic Naturals with 5 active ingredients. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Omega-3 Phospholipids by Nordic Naturals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 5 active ingredients: eicosapentaenoic acid and docosahexaenoic acid (two omega-3 fatty acids), other omega-3 fatty acids, phosphatidylcholine, and other phospholipids. Phospholipids are fat-like compounds that play a role in cell structure and may support liver and brain health.
The inactive ingredients are herring roe extract, purified deep sea fish oil, the soft gel capsule itself, vitamin E (D-alpha-tocopherol), and rosemary extract.
Does it work?
Not established
Phosphatidylcholine in this product is possibly effective for ulcerative colitis (a type of inflammatory bowel disease). For other conditions like nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer's disease, and anxiety, the evidence is insufficient to know whether it helps.
We don't have effectiveness data on file for the omega-3 fatty acids in this product.
How safe is it?
Well-documented data
Phosphatidylcholine is generally well tolerated at typical supplement doses. At very high doses (30 grams per day or more taken by mouth), it can cause digestive upset and diarrhea.
Smaller doses have sometimes caused bloating, altered taste, nausea, vomiting, and increased sweating. Choline (which comes from phosphatidylcholine) is needed during pregnancy, but we don't have enough data to know whether taking supplements beyond what you get from food is safe during pregnancy — talk with your doctor.
There also isn't enough reliable data on supplement use while breastfeeding; speak with your healthcare provider first.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. However, we hold no interaction information for the omega-3 fatty acids that make up most of this product, so check your exact medications with your doctor or pharmacist before taking it.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
If you're looking at this product for ulcerative colitis, phosphatidylcholine may be worth considering, though evidence is limited. The omega-3 content makes this a typical fish oil supplement, but we couldn't check those components for drug interactions.
Before you start, run your medications by your pharmacist or doctor, especially if you take blood thinners or are pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Omega-3 Phospholipids, straight from the product label.
| Brand | Nordic Naturals |
|---|---|
| Barcode (UPC) | 768990016219 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2020 |
| DSLD ID | 223169 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Omega-3 Phospholipids by Nordic Naturals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 15 Calorie(s) | -- |
| Total Fat | 1.5 Gram(s) | 2% |
| Eicosapentaenoic Acid | 190 mg | -- |
| Docosahexaenoic Acid | 200 mg | -- |
| Cholesterol | 40 mg | 13% |
| Total Omega-3 Fatty Acids | 500 mg | -- |
| Trans Fat | 0 Gram(s) | -- |
| Other Omega-3 Fatty Acids | 110 mg | -- |
| Saturated Fat | 0 Gram(s) | -- |
| Phosphatidylcholine | 300 mg | -- |
| Total Phospholipids | 350 mg | -- |
| other Phospholipids | 50 mg | -- |
Other ingredients: Herring Roe extract, purified deep sea Fish Oil, Soft Gel Capsule, D-Alpha-Tocopherol, Rosemary extract
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Molecularly distilled Guaranteed purity
It supports heart and cognitive health, and healthy cell development and maintenance.
Every batch of Nordic Naturals fish oils is tested by a third-party certified lab for environmental toxins, including heavy metals. All fish oils are in the triglyceride form and surpass the strictest international standards for purity and freshness. Certificates of Analysis available upon request.
Fish oil processed in Norway.
Healthy heart Brain health Cognitive function
The potent alternative to krill
Non GMO
No gluten, milk derivatives, or artificially derived colors or flavors.
Formula
Omega-3 Phospholipids combines one of our top-selling triglyceride-form fish oils with phospholipid-bound omega-3s from sustainably sourced herring roe. This unique formulation has naturally occurring phosphatidylcholine, and meets the expert-recommended dose of 500 mg omega-3 essential fatty acids per day.
500 mg omega-3 + 350 mg phospholipids
General Statements
Wild caught. Pure. No fishy aftertaste. Friend of the sea certified.
Nordic Naturals products are never sold under any store brand
Please recycle this content
Suggested/Recommended/Usage/Directions
Suggested Use: Two soft gels daily, or as directed by your health care professional or pharmacist.
Storage
Store in a cool, dry place, away from sunlight
Precautions
Do not take if tamper-evident seal is broken or missing
Keep out of the reach of children
Warning: Consult with your physician before using this product if you are allergic to iodine, or use blood thinners.
Warning: Consult with your physician before using this product if you are allergic to iodine, or use blood thinners.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
Non GMO Verified
Third-Party Purity Tested
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Omega-3 Phospholipids by Nordic Naturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Omega-3 Phospholipids by Nordic Naturals
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Total Omega-3 Fatty Acids
- › Eicosapentaenoic Acid
- › Docosahexaenoic Acid
- › Other Omega-3 Fatty Acids
Total Phospholipids
- › Phosphatidylcholine
- › Other Phospholipids
Other (inactive) ingredients: Herring Roe extract, Purified deep sea Fish Oil, Soft Gel Capsule, D-Alpha-Tocopherol, Rosemary extract. These complete the product’s ingredient list but are not active constituents.
Omega-3 Phospholipids by Nordic Naturals Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Omega-3 Phospholipids. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Omega-3 Phospholipids, from the product label.
Nordic Naturals
See all Nordic Naturals products- Name
- Nordic Naturals, Mfg.
- Street Address
- 111 Jennings Drive
- City
- Watsonville
- State
- CA
- ZipCode
- 95076
- Phone Number
- 800-662-2544
- Web Address
- nordicnaturals.com
Omega-3 Phospholipids by Nordic Naturals: Common Questions
Does Omega-3 Phospholipids by Nordic Naturals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this upset my stomach?
Can I take this if I'm pregnant?
Is it safe while I'm breastfeeding?
What is phosphatidylcholine supposed to do?
Does this product have any fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Omega-3 Phospholipids is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Omega-3 Phospholipids’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Omega-3 Phospholipids's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 15 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Phosphatidylcholine 15 references
- Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
- Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
- Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
- Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
- Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
- Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
- Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
- Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
- Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
- Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
- Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
- Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
- Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC