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Dietary supplement

OptiFlow Ingredients & Drug Interactions

by Bricker Labs

OptiFlow label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking OptiFlow against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

OptiFlow is a dietary supplement by Bricker Labs with 2 active ingredients. Its ingredients are commonly taken for heart health support, prostate health, antioxidant support.Based on those ingredients, 822 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Resvida Trans Resveratrol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against OptiFlow by Bricker Labs

Ask about any prescription or over-the-counter medication and we check it for interactions with OptiFlow by Bricker Labs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of OptiFlow by Bricker Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

OptiFlow contains two active ingredients: tomato concentrate and Resvida Trans Resveratrol. Tomato concentrate is a concentrated form of tomato; the product provides 2 active ingredients total.

The other ingredients listed are inactive excipients—microcrystalline cellulose, vegetarian cellulose, vegetable magnesium stearate, and silica—which help form and stabilize the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: natural solution for healthy blood circulation.
  • We looked for evidence on: Cardiovascular disease (CVD), Hypercholesterolemia, Hyperlipidemia, Hypertension, Metabolic syndrome, peripheral circulation — and 3 related terms.
  • The closest evidence on file: Resveratrol is rated "Possibly Ineffective" for Cardiovascular disease (CVD) (Natural Medicines).
  • Also on file: Resveratrol is rated "Possibly Ineffective" for Hypercholesterolemia, Metabolic syndrome.
  • Also on file: Resveratrol is rated "Insufficient Reliable Evidence To Rate" for Hypertension.

The evidence for OptiFlow's ingredients is mixed and often limited. Tomato concentrate shows possibly ineffective ratings for bladder cancer, breast cancer, and diabetes; for benign prostate enlargement, high cholesterol, and exercise-induced asthma, there isn't enough reliable evidence to rate it.

Resveratrol is rated possibly effective for obesity and hay fever (allergic rhinitis), but possibly ineffective for heart disease and high cholesterol. For most conditions, the data on file doesn't establish clear benefit.

The evidence, ingredient by ingredient Tomato Resveratrol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tomato concentrate is generally well tolerated in typical food amounts and in extract form, though concentrated supplements are less studied than whole tomatoes. Rare serious side effects can occur with excessive consumption of tomatine (a compound in tomato leaves and unripe green tomatoes), including dizziness, headache, and digestive upset.

An airborne allergy to tomato stem proteins has been reported in one case. Resveratrol is generally well tolerated at typical supplement doses, though higher doses may cause digestive upset, diarrhea, or loose stools.

Safety is not fully established long-term. During pregnancy, resveratrol safety information is insufficient—the data advises against supplement use.

While breastfeeding, the data also advises against it due to insufficient safety information. One case of a skin rash was reported in a trial and resolved after stopping resveratrol.

Side effects, ingredient by ingredient Tomato Resveratrol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Resveratrol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 823 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting OptiFlow, double-check your medications against these drug types: blood thinners and antiplatelet drugs (warfarin, aspirin, clopidogrel), and any medication broken down by your liver via the CYP2C19, CYP1A2, CYP2E1, or CYP3A4 pathways. These are Moderate-severity interactions.

Use the medication search tool on this page to look up your specific drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

OptiFlow may appeal to people interested in tomato and resveratrol supplements for general wellness, but the evidence for specific health claims is limited or mixed. If you take blood thinners or antiplatelet medications, or any prescription drug, check with us first—resveratrol can affect how your liver handles many medications.

If you're pregnant or breastfeeding, talk to your doctor or pharmacist before taking this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about OptiFlow, straight from the product label.

Brand Bricker Labs
Barcode (UPC) 042239280303
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jan 25, 2020
DSLD ID 211610
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for OptiFlow by Bricker Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
042239280303
IngredientAmount% DV
Tomato concentrate150 mg--
Resvida Trans Resveratrol30 mg--

Other ingredients: Microcrystalline Cellulose, Vegetarian Cellulose, Vegetable Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Natural solution for healthy blood circulation Starts to work within 90 minutes Naturally supports healthy circulation and healthy platelet function Improves blood flow in approximately 97% of individuals

Promotes healthy cardiovascular circulation Fast acting cardiovascular breakthrough supporting healthy platelets and smooth blood flow

Free of: wheat, sugar, soy, dairy, fish, preservatives, artificial colors or flavors.

Vegetarian

Gluten-free Non-GMO

Precautions

Consult your healthcare professional prior to use if you are pregnant, nursing, taking any medication, or have any medical conditions.

Keep out of reach of children.

Storage

Store product in cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Made in the USA with globally sourced ingredients

Science that makes sense

Brand IP Statement(s)

Fruitflow and Resvida are a trademark of DSM

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule daily between a meal or as directed by your health care professional.

Formula

Resvida FruitFlow

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

OptiFlow by Bricker Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

OptiFlow label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in OptiFlow by Bricker Labs

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Tomato concentrate

No known
interactions
150 mg per serving

Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people...

Tomato concentrate monograph & interactions

Resvida Trans Resveratrol

Interacts with
822 drugs
30 mg per serving

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While...

Resvida Trans Resveratrol monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Vegetarian Cellulose, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

OptiFlow by Bricker Labs Drug Interactions

Want to check YOUR meds against OptiFlow?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
822Drugs
822 Moderate

Ingredients driving the most interactions

Resvida Trans Resveratrol 822

Individual Drug Interactions

The ingredients in OptiFlow interact with 822 drugs. Click any drug to see the details.

1 of the 2 ingredients in OptiFlow interact with drugs. Each result below shows which ingredient is responsible. Resvida Trans Resveratrol

Each ingredient & the kinds of drugs it affects

For each ingredient in OptiFlow with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Resvida Trans Resveratrol5 drug types · 822 drugs

Anticoagulant/Antiplatelet Drugs

Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Resveratrol seems to have antiplatelet effects.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that resveratrol can inhibit CYP1A2 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that resveratrol can inhibit CYP2C19 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Resveratrol might increase levels of drugs metabolized by CYP2E1.
In vitro research suggests that resveratrol inhibits CYP2E1 isoenzyme. Also, a pharmacokinetic study shows that taking resveratrol 500 mg daily for 10 days prior to taking a single dose of chlorzoxazone 250 mg increases the maximum concentration of chlorzoxazone by about 54%, the area under the curve of chlorzoxazone by about 72%, and the half-life of chlorzoxazone by about 35%. Chlorzoxazone is used as a probe drug for CYP2E1.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that resveratrol can inhibit the CYP3A4 enzyme. However, clinical research shows that taking resveratrol 3000 mg daily for 8 weeks does not necessitate dose adjustments to medications metabolized by CYP3A4.

Likelihood Possible Evidence D
Resvida Trans Resveratrol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for OptiFlow, from the product label.

Bricker Labs

See all Bricker Labs products
Name
BrickerLabs
City
Chandler
State
AZ
ZipCode
85225
Phone Number
800 274 2537
Web Address
BrickerLabs.com
Pharmacist Counseling Corner

OptiFlow by Bricker Labs: Common Questions

Does OptiFlow by Bricker Labs interact with any medications?
Yes. Based on its ingredients, OptiFlow has a known interaction with 822 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
OptiFlow contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take OptiFlow if I'm pregnant or breastfeeding?
For tomato concentrate, the data rates it likely safe in pregnancy and lactation. However, for resveratrol, there isn't enough safety information—the data advises against supplement use during pregnancy and while breastfeeding. Talk with your doctor or pharmacist to weigh your individual situation and decide what's right for you.
What side effects might I experience?
Resveratrol most commonly causes diarrhea, gastrointestinal discomfort, or loose stools. Tomato concentrate is well tolerated in typical amounts. Rare serious side effects from excessive tomatine (found in tomato leaves and green tomatoes) include dizziness, headache, and digestive upset, though these would be unlikely at normal supplement doses.
Does OptiFlow actually work for weight loss or hay fever?
Resveratrol is rated possibly effective for obesity and hay fever based on the evidence we have on file. That means there's some supporting research, but it's not conclusive. Results vary, and this product isn't a substitute for medical treatment if you have a diagnosed condition.
Is this safe if I'm on other medications?
Resveratrol can interact with blood thinners and antiplatelet drugs, raising your bleeding risk. It may also affect how your liver processes many other prescription medications. Check your exact drugs with our medication tool on this page before you start.
Why does OptiFlow have so many medication interactions listed?
Resveratrol can theoretically inhibit several liver enzymes (CYP2C19, CYP1A2, CYP2E1, CYP3A4) that break down hundreds of different medications. This affects a large number of drugs across many categories. Most of these interactions haven't been seen in actual patients, but they're flagged because the potential exists.
What are the inactive ingredients for?
Microcrystalline cellulose, vegetarian cellulose, vegetable magnesium stearate, and silica are excipients—they bind the active ingredients together, form the capsule, and help the product stay stable on the shelf. They're not therapeutic ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

OptiFlow label
Go deeper

The Full Monographs Behind OptiFlow’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tomato

Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people. Concentrated tomato or lycopene supple...

Read the full Tomato monograph → Herb & supplement monograph

Resveratrol

Interacts with 822 drugs

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While lab and animal studies are promising, s...

Read the full Resveratrol monograph →
Sources

Sources & How We Checked

OptiFlow's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tomato 3 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Asero R, Mistrello G, Amato S. Airborne allergy to tomato proteins. Allergy. 2010;65(12):1626-7. PubMed
  3. Friedman M. Tomato Glycoalkaloids: Role in the Plant and in the Diet. J Agric Food Chem. 2002;50(21):5751-80. PubMed

See these in context on the Tomato monograph →

Resveratrol 24 references
  1. Soleas GJ, Diamandis EP, Goldberg DM. Resveratrol: a molecule whose time has come? And gone? Clin Biochem 1997;30:91-113.
  2. Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
  3. Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
  4. Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
  5. Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
  6. Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
  7. Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
  8. Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
  9. Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
  10. Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
  11. Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
  12. Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
  13. Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
  14. Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
  15. la, Porte C., Voduc, N., Zhang, G., Seguin, I., Tardiff, D., Singhal, N., and Cameron, D. W. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Cli PubMed
  16. Brown, V. A., Patel, K. R., Viskaduraki, M., Crowell, J. A., Perloff, M., Booth, T. D., Vasilinin, G., Sen, A., Schinas, A. M., Piccirilli, G., Brown, K., Steward, W. P., Gescher, A. J., and Brenner, D. E. Repeat dose study of the cancer chemopreventive
  17. Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
  18. Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Resveratrol does not benefit patients with nonalcoholic fatty
  19. Bedada SK, Neerati P. Resveratrol Pretreatment Affects CYP2E1 Activity of Chlorzoxazone in Healthy Human Volunteers. Phytother Res. 2016;30(3):463-8. PubMed
  20. Lin CT, Sun XY, Lin AX. Supplementation with high-dose trans-resveratrol improves ultrafiltration in peritoneal dialysis patients: a prospective, randomized, double-blind study. Ren Fail. 2016;38(2):214-21. PubMed
  21. Li Q, Yang G, Xu H, Tang S, Lee WY. Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Med Ther 2021;21(1):214. PubMed
  22. McCreary MR, Schnell PM, Rhoda DA. Randomized double-blind placebo-controlled proof-of-concept trial of resveratrol for outpatient treatment of mild coronavirus disease (COVID-19). Sci Rep 2022;12(1):10978. PubMed
  23. Abdelhaleem IA, Brakat AM, Adayel HM, Asla MM, Rizk MA, Aboalfetoh AY. The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and meta-analysis. Med Clin (Barc) 2022;158(12):576-585. PubMed
  24. Badaoui A. Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product. Contact Dermatitis 2022.

See these in context on the Resveratrol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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