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Dietary supplement

Organic Beetroot Ingredients & Drug Interactions

by Peak Performance

Organic Beetroot label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Beetroot against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Beetroot is a dietary supplement by Peak Performance with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beet Fruit Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Beetroot by Peak Performance

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Beetroot by Peak Performance — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Beetroot by Peak Performance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Peak Performance Organic Beetroot is a single-ingredient supplement containing beet fruit extract in capsule form. The extract delivers betanin, the pigment that gives beets their deep red color and is thought to be the active compound responsible for the supplement's effects.

The capsule also contains cellulose and water as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Beet's overall clinical evidence instead.

Moderate

Some clinical evidence supports Beet for:

Why this rating?
  • The label markets general wellness (“antioxidant support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Athletic performance — rated "Possibly Effective" (Natural Medicines).
  • On file: Exercise-induced muscle soreness — rated "Possibly Effective" (Natural Medicines).

The evidence for beet supplement is mixed. It's rated possibly effective for athletic performance and exercise-induced muscle soreness, meaning small studies suggest it may help, but the data isn't conclusive yet.

For other uses — cognitive function and dyslipidemia (cholesterol issues) — the evidence is insufficient to say one way or the other. Beet is rated possibly ineffective for chronic obstructive pulmonary disease (COPD).

The evidence, ingredient by ingredient Beet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beet as a food is widely eaten and well tolerated in most adults. However, concentrated supplements lack the long-term safety data we have for the whole food, so use caution.

The most common side effect is red or dark stools — harmless and temporary. Rare serious effects at very large doses include low blood calcium (hypocalcemia) and kidney damage.

One case reported black stools and gastrointestinal symptoms in an older patient taking beet pills alongside blood thinners, though the risk of serious bleeding was assessed as low.

Side effects, ingredient by ingredient Beet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beet.
  • The most serious interaction on file is rated Moderate.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Peak Performance Organic Beetroot, double-check with your doctor or pharmacist if you take any CYP3A4 substrates (a large group of drugs including certain statins, some cancer medications, and immunosuppressants) — beet may increase their levels and effects, which is a Moderate concern. Also flag any blood pressure medications you're on, since beet's nitrates can lower blood pressure further.

If you take medications that your liver breaks down via the CYP1A2 pathway, beet may reduce their effectiveness.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you're looking to support athletic performance or reduce exercise soreness, beet extract is possibly effective based on current evidence — but it's not a slam-dunk. The real consideration is whether it interacts with your medications: 862 drugs are theoretically affected, especially blood pressure medications and those your liver breaks down through the CYP3A4 pathway.

Talk with your doctor or pharmacist about your specific medications before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 11, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Beetroot, straight from the product label.

Brand Peak Performance
Barcode (UPC) X002IC8Z9H
Net contents 60 Vegan Capsule(s)
Market status On market
Date entered into DSLD Apr 11, 2022
DSLD ID 261836
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Beetroot by Peak Performance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegan Capsule(s)
Maximum serving Sizes:
2 Vegan Capsule(s)
Servings per container
30
UPC/BARCODE
X002IC8Z9H
IngredientAmount% DV
Beet Fruit Extract1200 mg--

Other ingredients: Cellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: For best results take 2 capsules daily or as recommended by your healthcare practitioner.

Formula

Peak Performance Organic Beetroot is rich in antioxidants including betaine.

Formulation

We grow our beets in clean and safe ecological environments in the USA. We carefully harvest and avoid artificial processing in order to preserve their maximum nutrients.

Benefits: Naturally cultivated + vegan friendly

Free of heavy metals, gluten, GMOs, additives, preservatives, artificial colors, flavors, pesticides, soy, dairy and fillers.

Not manufactured with yeast, wheat, gluten, milk, egg, fish, shellfish or tree nut ingredients.

Made with Non GMO Ingredients

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

General Statements

Save 20% BuyPeakPerformance.com

Storage

Store in a cool, dry place after opening.

Precautions

Caution: For adults only.

Consult a physician if you are pregnant/nursing, taking medication or have a medical condition.

Keep out of reach of children.

Seals/Symbols

GMP Good Manufacturing Practice Consistent Quality Formulated in the USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Beetroot by Peak Performance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Beetroot label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Beetroot by Peak Performance

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Vegan Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Beet Fruit Extract

Interacts with
861 drugs
1200 mg per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet Fruit Extract monograph & interactions

Other (inactive) ingredients: Cellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Beetroot by Peak Performance Drug Interactions

Want to check YOUR meds against Organic Beetroot?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
861Drugs
643 Moderate 218 Minor

Ingredients driving the most interactions

Beet Fruit Extract 861

Individual Drug Interactions

The ingredients in Organic Beetroot interact with 861 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Beetroot interact with drugs. Each result below shows which ingredient is responsible. Beet Fruit Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Beetroot with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beet Fruit Extract3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Beet Fruit Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Beetroot, from the product label.

Peak Performance

See all Peak Performance products
Name
Peak Performance Life LLC
City
Henderson
State
NV
ZipCode
89052
Web Address
www.BuyPeakPerformance.com
Pharmacist Counseling Corner

Organic Beetroot by Peak Performance: Common Questions

Does Organic Beetroot by Peak Performance interact with any medications?
Yes. Based on its ingredients, Organic Beetroot has a known interaction with 861 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Beetroot contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will my stools really turn red if I take this?
Yes, red or dark stools are the most common side effect and are completely harmless. It's just the beet pigment passing through your system. It usually clears up on its own.
Does this actually improve athletic performance?
It's rated possibly effective based on small studies, so there's some promise — but the evidence isn't strong enough to say it definitely will. Results vary from person to person.
Is beet supplement safe if I'm taking blood thinners?
There's a documented case of a patient on blood thinners who experienced black stools after taking beet pills, so this is worth discussing with your doctor or pharmacist before you start. They can assess your specific situation.
What is betanin, and why does it matter?
Betanin is the deep red pigment in beets and the compound thought to drive the supplement's effects. It's also what can interact with how your liver breaks down certain medications.
Is this safe if I'm pregnant or breastfeeding?
The product facts don't contain safety data for pregnancy or breastfeeding with concentrated beet supplements. Talk with your doctor or pharmacist before taking it if you're pregnant or nursing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Beetroot is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Beetroot label
Go deeper

The Full Monographs Behind Organic Beetroot’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beet

Interacts with 861 drugs

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...

Read the full Beet monograph →
Sources

Sources & How We Checked

Organic Beetroot's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 14 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
  3. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  4. Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
  5. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
  6. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  7. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  8. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
  9. Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
  10. Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
  11. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  12. Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
  13. Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
  14. Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed

See these in context on the Beet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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